Apoptotic And Non Apoptotic Cell Death

Author : Shigekazu Nagata,Hiroyasu Nakano
Publisher : Springer
Page : 183 pages
File Size : 52,6 Mb
Release : 2017-04-07
Category : Medical
ISBN : 9783319239132

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Apoptotic and Non-apoptotic Cell Death by Shigekazu Nagata,Hiroyasu Nakano Pdf

This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skin diseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells. Offering insights into cell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.

Author : Evangelos Giampazolias
Publisher : Unknown
Page : 0 pages
File Size : 40,7 Mb
Release : 2016
Category : Apoptosis
ISBN : OCLC:990622380

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Investigating Non-apoptotic Cell Death in Cancer by Evangelos Giampazolias Pdf

Author : Tobias Ntuli
Publisher : BoD – Books on Demand
Page : 448 pages
File Size : 46,6 Mb
Release : 2015-12-16
Category : Science
ISBN : 9789535122364

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Cell Death by Tobias Ntuli Pdf

This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Author : James A. Radosevich
Publisher : John Wiley & Sons
Page : 784 pages
File Size : 52,5 Mb
Release : 2018-09-18
Category : Science
ISBN : 9781119432357

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Apoptosis and Beyond by James A. Radosevich Pdf

These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

Author : George Studzinski
Publisher : OUP Oxford
Page : 267 pages
File Size : 48,6 Mb
Release : 1999-12-09
Category : Science
ISBN : 9780191566004

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Apoptosis by George Studzinski Pdf

This text is designed to provide conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis as distinguished from necrosis and nonspecific cell DNA damage, are followed by a systematic examination of the established and the principal novel methodologies utilized by some leading laboratories conducting research on apoptosis. The organization is on the lines of signalling for apoptosis, the apoptotic cascade, and the execution of apoptosis. A wide variety of procedures are provided which will enable the reader to participate in cutting-edge research.

Author : Christopher D. Gregory
Publisher : Springer
Page : 247 pages
File Size : 46,5 Mb
Release : 2016-08-24
Category : Medical
ISBN : 9783319394060

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Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy by Christopher D. Gregory Pdf

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.

Author : Lawrence B. Shultz
Publisher : Nova Publishers
Page : 228 pages
File Size : 50,7 Mb
Release : 2007
Category : Apoptosis
ISBN : 1600215084

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Cell Apoptosis by Lawrence B. Shultz Pdf

Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book deals with cell apoptosis regulation and environmental factors.

Author : Victor R. Preedy
Publisher : CRC Press
Page : 650 pages
File Size : 52,9 Mb
Release : 2010-07-19
Category : Medical
ISBN : 9781439845431

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Apoptosis by Victor R. Preedy Pdf

Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced liver disease, chronic back pain, and cardiovascular health. With 40 chapters written by highly respected authorities, this single source reference provides researchers and scientists with the foundation they need.

Author : Estee Kurant,Amiram Ariel,Kirsten Lauber
Publisher : Frontiers Media SA
Page : 294 pages
File Size : 45,6 Mb
Release : 2018-12-27
Category : Electronic
ISBN : 9782889456888

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Apoptotic Cell Clearance in Health and Disease by Estee Kurant,Amiram Ariel,Kirsten Lauber Pdf

Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event for phagocytes. Particularly, efferocytosis has an important impact on the inflammation-resolution axis as well as embryonic development and tissue morphogenesis. Deficiencies in these processes can result in health threats, such as autoimmunity, atherosclerosis, bone loss, obesity, infertility, neurodegeneration, fibrosis and cancer. This eBook brings together 24 original research and review manuscripts that cover various aspects of apoptotic cell removal during normal development and homeostasis as well as in tumorigenesis and regenerative processes following injury.

Author : MingLi Li
Publisher : Unknown
Page : 0 pages
File Size : 53,6 Mb
Release : 2017
Category : Electronic
ISBN : OCLC:1181600970

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Regulation of Apoptosis-induced Proliferation and Non-apoptotic Cell Death in Drosophila by MingLi Li Pdf

Author : Anonim
Publisher : Academic Press
Page : 352 pages
File Size : 45,9 Mb
Release : 2014-07-24
Category : Science
ISBN : 9780128016190

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Regulated Cell Death Part B by Anonim Pdf

Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Regulated Cell Death Part A & Part B contains sections on such topics as apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches

Author : Anonim
Publisher : Elsevier
Page : 570 pages
File Size : 55,6 Mb
Release : 2001-05-30
Category : Science
ISBN : 9780080496610

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Apoptosis by Anonim Pdf

Apoptosis provides a current and comprehensive collection of methods for the study of cell death. Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics from the cellular and organismal to the molecular and anatomical. The methods are illustrated with user-friendly recipes and over 100 tables, halftones, and diagrams. Current methodologies for studying cell death Wide range of model systems Molecular, biochemical, cellular, and genetic approaches Complements the original Cell Death volume Up-to-date methodology for a fast moving field Designed with the needs of both basic scientists and clinicians in mind Authors are leaders in their respective fields

Author : P. Erhard,Ambrus Toth
Publisher : Humana Press
Page : 400 pages
File Size : 54,6 Mb
Release : 2009-07-15
Category : Science
ISBN : 1603270167

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Apoptosis by P. Erhard,Ambrus Toth Pdf

The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research. In Apoptosis: Methods and Protocols, Second Edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. Presented from several different research perspectives, the volume contains sections covering detection of apoptosis, detection of non-apoptotic cell death, modifications of apoptotic proteins during apoptosis, the analysis of its major regulators, as well as analysis of apoptosis in different organs and in model organisms. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Apoptosis: Methods and Protocols, Second Edition constitutes a key technical reference to the significant methodologies used in the field, and offers beginners and experienced researchers powerful tools to illuminate the phenomena of programmed cell death.

Author : Hugo Barcenilla,David Diaz
Publisher : Springer Nature
Page : 215 pages
File Size : 55,9 Mb
Release : 2022-09-10
Category : Medical
ISBN : 9781071625538

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Apoptosis and Cancer by Hugo Barcenilla,David Diaz Pdf

This volume discusses methods used in the fields of molecular and cellular biology for detecting and studying cell death, especially in cancer and cancer therapy. Chapters in this book cover topics such as non-destructive, real-time Annexin V apoptosis assay; assessment of the immune response to tumor cell apoptosis and efferocytosis; mass cytometry assessment of cell phenotypes and signaling states in human whole blood; cell cycle analysis of ER stress and autophagy; and simultaneous detection of inflammasome activation and membrane damage during pyroptosis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Apoptosis and Cancer: Methods and Protocols is a valuable resource and practical guide for both novice and expert researchers looking into the “meaning of death.”

Author : Seamus J. Martin
Publisher : S. Karger AG (Switzerland)
Page : 0 pages
File Size : 53,9 Mb
Release : 1997
Category : Apoptosis
ISBN : 3805565798

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Apoptosis and Cancer by Seamus J. Martin Pdf

The past five years have witnessed an explosion of research efforts in the study of how cells die. This book provides an up-to-date overview of our current knowledge of apoptosis and how discoveries in this area impact on our understanding of cancer. By synthesizing many of the recent developments in this area and placing them in perspective, it fulfills an important need. All the contributions are written by experts in their respective fields. The first two chapters give a basic introduction to the cell death machinery and its role in tumor development and progression; subsequent chapters cover current aspects of apoptosis research, including the involvement of cell cycle-related proteins (e.g. cyclin-dependent kinases) in apoptosis, the role of Bcl-2, Bcr-Abl, Rb, p53 and myc in the regulation of cell death, and apoptosis in the context of specific neoplasms such as cancer of the prostate, kidney, leukemia and neuroblastoma. It is also discussed how insights into the regulation of apoptosis may be exploited for designing new drugs aimed at eliminating malignant cells. Compiling the most recent research results on the relationship between apoptosis and cancer in one handy volume, this book will provide a valuable reference for scientists working in cancer research as well as newcomers to the field.