Automated Sample Preparation

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Automated Sample Preparation

Author : Hans-Joachim Hubschmann
Publisher : John Wiley & Sons
Page : 482 pages
File Size : 55,7 Mb
Release : 2022-02-22
Category : Science
ISBN : 9783527345076

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Automated Sample Preparation by Hans-Joachim Hubschmann Pdf

An essential guide to the proven automated sample preparation process While the measurement step in sample preparation is automated, the sample handling step is manual and all too often open to risk and errors. The manual process is of concern for accessing data quality as well as producing limited reproducibility and comparability. Handbook of Automated Sample Preparation for CG-MS and LC-MS explores the advantages of implementing automated sample preparation during the handling phase for CG-MS and LC-MS. The author, a noted expert on the topic, includes information on the proven workflows that can be put in place for many routine and regulated analytical methods. This book offers a guide to automated workflows for both on-line and off-line sample preparation. This process has proven to deliver consistent and comparable data quality, increased sample amounts, and improved cost efficiency. In addition, the process follows Standard Operation Procedures that are essential for audited laboratories. This important book: Provides the information and tools needed for the implementation of instrumental sample preparation workflows Offers proven and detailed examples that can be adapted in analytical laboratories Shows how automated sample preparation can reduce cost per sample, increase sample amounts, and produce faster results Includes illustrative examples from various fields such as chemistry to food safety and pharmaceuticals Written for personnel in analytical industry, pharmaceutical, and medical laboratories, Handbook of Automated Sample Preparation for CG-MS and LC-MS offers the much-needed tools for implementing the automated sample preparation for analytical laboratories.

High Throughput Bioanalytical Sample Preparation

Author : David A. Wells
Publisher : Elsevier
Page : 0 pages
File Size : 44,7 Mb
Release : 2023-11-01
Category : Science
ISBN : 0444637583

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High Throughput Bioanalytical Sample Preparation by David A. Wells Pdf

High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies, Second Edition, is the go-to resource for industrial analytical chemists and others seeking the latest techniques for optimizing sample preparation in their everyday workflow. Outlining the latest preparation techniques from around the globe, this helpful guide provides answers to questions, including 'How do I automate a procedure?', 'How do I work to reduce matrix interferences?' 'Could I do this procedure online instead of in a manual batch?' 'What sorbent materials are available in the market?' 'How do I use a cation exchange resin?' 'What has been published on micro-sampling techniques?', and more. Featuring detailed coverage of the newer techniques that have emerged since the first edition was published, the book includes discussions on micro sampling and molecularly imprinted polymers, addresses the workflow pain points associated with extraction process efficiency, and outlines exactly how to optimize productivity through enhanced method development. Combining a step-by-step approach with a thorough explanation of the technology, this new edition features 40% new content and 60% revised content, accurately and thoroughly capturing the latest developments in research since the previous edition published in 2003.

Automation Solutions for Analytical Measurements

Author : Heidi Fleischer,Kerstin Thurow
Publisher : John Wiley & Sons
Page : 160 pages
File Size : 51,6 Mb
Release : 2017-08-30
Category : Science
ISBN : 9783527805327

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Automation Solutions for Analytical Measurements by Heidi Fleischer,Kerstin Thurow Pdf

The first book dedicated specifically to automated sample preparation and analytical measurements, this timely and systematic overview not only covers biological applications, but also environmental measuring technology, drug discovery, and quality assurance. Following a critical review of realized automation solutions in biological sciences, the book goes on to discuss special requirements for comparable systems for analytical applications, taking different concepts into consideration and with examples chosen to illustrate the scope and limitations of each technique.

Sample Preparation of Pharmaceutical Dosage Forms

Author : Beverly Nickerson
Publisher : Springer Science & Business Media
Page : 400 pages
File Size : 53,7 Mb
Release : 2011-08-05
Category : Medical
ISBN : 9781441996312

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Sample Preparation of Pharmaceutical Dosage Forms by Beverly Nickerson Pdf

This book is intended to serve as a resource for analysts in developing and troubleshooting sample preparation methods. These are critical activities in providing accurate and reliable data throughout the lifecycle of a drug product. This book is divided into four parts: • Part One covers dosage form and diluent properties that impact sample preparation of pharmaceutical dosage forms and the importance of sampling considerations in generating data representative of the drug product batch. • Part Two reviews specific sample preparation techniques typically used with pharmaceutical dosage forms. • Part Three discusses sample preparation method development for different types of dosage forms including addressing drug excipient interactions and post extraction considerations, as well as method validation and applying Quality by Design (QbD) principles to sample preparation methods. • Part Four examines additional topics in sample preparation including automation, investigating aberrant potency results, green chemistry considerations for sample preparation and the ideal case where no sample preparation is required for sample analysis.

Acceleration and Automation of Solid Sample Treatment

Author : J.L. Luque García,M.D. Luque de Castro
Publisher : Elsevier
Page : 556 pages
File Size : 51,6 Mb
Release : 2002-08-09
Category : Science
ISBN : 0080525865

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Acceleration and Automation of Solid Sample Treatment by J.L. Luque García,M.D. Luque de Castro Pdf

This book aims to provide scientists with information about a series of techniques that can be used with a view to facilitating the transformation of the sample to an appropriate state for subsequent detection or quantitation of its components of interest. The techniques dealt with range from the very simple ones (e.g. freeze-drying) to other more complex ones (e.g. glow discharge and laser-induced breakdown sampling). This is the first compilation ever on the subjects of acceleration of solid sample pretreatment; automation of solid sample pretreatment; and integration of solid sample pretreatment and detection. Readers will find here the information required to compare and select the best choice for each sample treatment need and ways to facilitate or automate the most complex and time-consuming step of the analytical process when solid samples are involved.

Sampling and Sample Preparation in Field and Laboratory

Author : Janusz Pawliszyn
Publisher : Elsevier
Page : 1170 pages
File Size : 52,7 Mb
Release : 2002-09-09
Category : Science
ISBN : 0444505113

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Sampling and Sample Preparation in Field and Laboratory by Janusz Pawliszyn Pdf

This title is the first comprehensive book on sampling and modern sample preparation techniques and has several main objectives: to facilitate recognition of sample preparation as both an integral part of the analytical process; to present a fundamental basis and unified theoretical approach for the professional development of sample preparation; to emphasize new developments in sample preparation technology; and to highlight the future impact of sample preparation on new directions in analytical science, particularly automation, miniaturization and field implementation. Until recently, there has been relatively little scientific interest in sampling and sample preparation, however this situation is presently changing as sampling and sample preparation become integral parts of the analytical process with their own unique challenges and research opportunities. Sampling and Sample Preparation for Field and Laboratory is an essential resource for all analytical chemists, and in particular those involved in method development. Not only does it cover the fundamental aspects of extraction, it also covers applications in various matrices and includes sampling strategies and equipment and how these can be integrated into the analytical process for maximum efficiency.

Comprehensive Sampling and Sample Preparation

Author : Josep M. Bayona,Paola Dugo,X. Chris Le,Hian Kee Lee,Xing-Fang Li,Heather Lord
Publisher : Academic Press
Page : 2998 pages
File Size : 50,9 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780123813749

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Comprehensive Sampling and Sample Preparation by Josep M. Bayona,Paola Dugo,X. Chris Le,Hian Kee Lee,Xing-Fang Li,Heather Lord Pdf

Comprehensive Sampling and Sample Preparation is a complete treatment of the theory and methodology of sampling in all physical phases and the theory of sample preparation for all major extraction techniques. It is the perfect starting point for researchers and students to design and implement their experiments and support those experiments with quality-reviewed background information. In its four volumes, fundamentals of sampling and sample preparation are reinforced through broad and detailed sections dealing with Biological and Medical, Environmental and Forensic, and Food and Beverage applications. The contributions are organized to reflect the way in which analytical chemists approach a problem. It is intended for a broad audience of analytical chemists, both educators and practitioners of the art and can assist in the preparation of courses as well in the selection of sampling and sample preparation techniques to address the challenges at hand. Above all, it is designed to be helpful in learning more about these topics, as well as to encourage an interest in sampling and sample preparation by outlining the present practice of the technology and by indicating research opportunities. Sampling and Sample preparation is a large and well-defined field in Analytical Chemistry, relevant for many application areas such as medicine, environmental science, biochemistry, pharmacology, geology, and food science. This work covers all these aspects and will be extremely useful to researchers and students, who can use it as a starting point to design and implement their experiments and for quality-reviewed background information There are limited resources that Educators can use to effectively teach the fundamental aspects of modern sample preparation technology. Comprehensive Sampling and Sample Preparation addresses this need, but focuses on the common principles of new developments in extraction technologies rather than the differences between techniques thus facilitating a more thorough understanding Provides a complete overview of the field. Not only will help to save time, it will also help to make correct assessments and avoid costly mistakes in sampling in the process Sample and sample preparation are integral parts of the analytical process but are often less considered and sometimes even completely disregarded in the available literature. To fill this gap, leading scientists have contributed 130 chapters, organized in 4 volumes, covering all modern aspects of sampling and liquid, solid phase and membrane extractions, as well as the challenges associated with different types of matrices in relevant application areas

Development of Alternative Green Sample Preparation Techniques

Author : Emanuela Gionfriddo
Publisher : MDPI
Page : 230 pages
File Size : 46,9 Mb
Release : 2020-11-23
Category : Science
ISBN : 9783039434688

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Development of Alternative Green Sample Preparation Techniques by Emanuela Gionfriddo Pdf

The Special Issue of Separations, “Development of Alternative Green Sample Preparation Techniques”, provides an overview on recent trends in green sample preparation. This Special Issue of Separations collates 11 impressive contributions that describe the state-of-the-art in the development of green extraction technologies, from green materials for microextraction to the development of new sampling devices geometries for enhanced extraction efficiency and analysis throughput.

Proteomics Sample Preparation

Author : Jörg von Hagen
Publisher : John Wiley & Sons
Page : 498 pages
File Size : 40,7 Mb
Release : 2011-08-24
Category : Science
ISBN : 9783527644698

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Proteomics Sample Preparation by Jörg von Hagen Pdf

This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences. By addressing the topic from three different angles -- sample, method and aim of the study -- this practical reference has something for every proteomics researcher. Following an introduction to the field, the book looks at sample preparation for specific techniques and applications and finishes with a section on the preparation of sample types. For each method described, a summary of the pros and cons is given, as well as step-by-step protocols adaptable to any specific proteome analysis task.

Sample Preparation in Chromatography

Author : S.C. Moldoveanu,V. David
Publisher : Elsevier
Page : 949 pages
File Size : 47,7 Mb
Release : 2002-05-08
Category : Science
ISBN : 9780080540702

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Sample Preparation in Chromatography by S.C. Moldoveanu,V. David Pdf

Sample preparation is an essential step in many analyses. This book approaches the topic of sample preparation in chromatography in a methodical way, viewing it as a logical connection between sample collection and analytical chromatography. Providing a guide for choosing the appropriate sample preparation for a given analysis, this book describes various ways to process the sample, explaining the principle, discussing the advantages and disadvantages, describing the applicability to different types of samples, and showing the fitness to specific chromatographic determinations. The first part of the book contains an overview of sample preparation showing its relation to sample collection and to the core chromatographic analysis. The second part covers procedures that do not use chemical modifications of the analyte and includes methods for sample dissolution, concentration and cleanup designed mainly for modifying the initial matrix of the sample. This part starts with conventional separations such as filtration and distillation and finishes with more advanced techniques such as solid phase extraction and electroseparations. The third part gives a description of the chemical modifications that can be performed on a sample either for fractionation purposes or to improve a specific property of the analyte. This part includes derivatizations, polymer chemical degradations, and pyrolysis.

Modern Sample Preparation for Chromatography

Author : Serban C. Moldoveanu,Victor David
Publisher : Elsevier
Page : 698 pages
File Size : 42,5 Mb
Release : 2021-02-24
Category : Science
ISBN : 9780323898201

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Modern Sample Preparation for Chromatography by Serban C. Moldoveanu,Victor David Pdf

Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure’s advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. Presents numerous techniques applied for sample preparation for chromatographic analysis Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis

SME Mineral Processing and Extractive Metallurgy Handbook

Author : Courtney A. Young
Publisher : Society for Mining, Metallurgy & Exploration
Page : 2258 pages
File Size : 41,7 Mb
Release : 2019-02-01
Category : Technology & Engineering
ISBN : 9780873353854

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SME Mineral Processing and Extractive Metallurgy Handbook by Courtney A. Young Pdf

This landmark publication distills the body of knowledge that characterizes mineral processing and extractive metallurgy as disciplinary fields. It will inspire and inform current and future generations of minerals and metallurgy professionals. Mineral processing and extractive metallurgy are atypical disciplines, requiring a combination of knowledge, experience, and art. Investing in this trove of valuable information is a must for all those involved in the industry—students, engineers, mill managers, and operators. More than 192 internationally recognized experts have contributed to the handbook’s 128 thought-provoking chapters that examine nearly every aspect of mineral processing and extractive metallurgy. This inclusive reference addresses the magnitude of traditional industry topics and also addresses the new technologies and important cultural and social issues that are important today. Contents Mineral Characterization and AnalysisManagement and ReportingComminutionClassification and WashingTransport and StoragePhysical SeparationsFlotationSolid and Liquid SeparationDisposalHydrometallurgyPyrometallurgyProcessing of Selected Metals, Minerals, and Materials

Biochemical Analysis Tools

Author : Oana-Maria Boldura,Cornel Balta,Prof Nasser Awwad
Publisher : BoD – Books on Demand
Page : 207 pages
File Size : 54,9 Mb
Release : 2020-06-24
Category : Science
ISBN : 9781789848564

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Biochemical Analysis Tools by Oana-Maria Boldura,Cornel Balta,Prof Nasser Awwad Pdf

This book explores the role of nucleic acid analysis and the advances it has led to in the field of life sciences. The first section is a collection of chapters covering experimental methods used in molecular biology, the techniques adjacent to these methods, and the steps of analysis before and after obtaining raw DNA data. The second section deals with the principles of chromatography, method development, sample preparation, and industrial applications.

A Handbook of Bioanalysis and Drug Metabolism

Author : Gary Evans
Publisher : CRC Press
Page : 412 pages
File Size : 42,7 Mb
Release : 2004-03-29
Category : Medical
ISBN : 0203642538

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A Handbook of Bioanalysis and Drug Metabolism by Gary Evans Pdf

Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.

Devices and Systems for Laboratory Automation

Author : Kerstin Thurow,Steffen Junginger
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 45,5 Mb
Release : 2022-08-03
Category : Science
ISBN : 9783527829439

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Devices and Systems for Laboratory Automation by Kerstin Thurow,Steffen Junginger Pdf

Devices and Systems for Laboratory Automation Structured Overview on the Available Systems and Devices for Laboratory Automation Choosing the right systems and devices for the automation in any given laboratory is an essential part for the process to succeed. As relevant information to make an informed choice is not always readily available, a structured overview is essential for modern scientists. This book provides an introduction into laboratory automation and an overview of the necessary devices and systems. Sample topics discussed by the two well-qualified authors include: Specific requirements the automation needs to fulfill such as liquid delivery, low volume delivery, solid delivery, and sample preparation An overview on robots and mobile robots Common interfaces in laboratory automation For scientists and all individuals working in laboratories, the work serves as an indispensable resource in helping to make laboratory processes more streamlined, effective, and efficient.