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Author : Itzhak Ofek,David L. Hasty,Ronald J. Doyle
Publisher : Unknown
Page : 440 pages
File Size : 45,9 Mb
Release : 2003
Category : Bacteria
ISBN : UOM:39015056846515
Author : Itzhak Ofek,Ronald J. Doyle
Publisher : Springer Science & Business Media
Page : 585 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468464351
Attachment to host cells or tissues is often the first step in the establishment of bacterial infections. A complex array of recognition, attachment, and virulence factors is involved in this process, which recent research has greatly illuminated. This comprehensive and authoritative volume discusses the specific cell and tissue-specific affinities of pathogenic microorganisms, including bioinorganic surfaces such as teeth, and is an essential reference for researchers and students of host-pathogen interactions.
Author : Michael Wilson
Publisher : Cambridge University Press
Page : 358 pages
File Size : 44,9 Mb
Release : 2010-01-28
Category : Science
ISBN : 9781139437639
This book is about the adhesion of bacteria to their human hosts. Although adhesion is essential for maintaining members of the normal microflora in/on their host, it is also the crucial first stage in any infectious disease. It is important, therefore, to fully understand the mechanisms underlying bacterial adhesion so that we may be able to develop methods of maintaining our normal (protective) microflora, and of preventing pathogenic bacteria from initiating an infectious process. These topics are increasingly important because of the growing prevalence of antibiotic-resistant bacteria and, consequently, the need to develop alternative approaches for the prevention and treatment of infectious diseases. This book describes the bacterial structures responsible for adhesion and the molecular mechanisms underlying the adhesion process. It also deals with the consequences of adhesion for both the adherent bacterium and the host cell/tissue to which it has adhered.
Author : M. Fletcher,D.C. Savage
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 54,9 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461565147
Study of the phenomena of bacterial adhesion to surfaces has accelerated considerably over the past 10 to 15 years. During this period, microbiologists have become increasingly aware that attachment to a substratum influences considerably the activities and structures of microbial cells. Moreover, in many cases attached communities of cells have important effects on their substratum and the surrounding environment. Such phenomena are now known to be important in plant and animal hosts, water and soil ecosystems, and man-made structures and industrial processes. Much work on microbial adhesion in the early 1970s was descriptive. Those studies were important for detecting and describing the phenomena of bacterial adhesion to substrata in various environments; the findings have been presented in numerous recently published, excellent books and reviews. In some studies, attempts were made to elucidate some funda mental principles controlling adhesion processes in different environments containing a variety of microorganisms. Common threads have been observed occasionally in different studies. Taken as a whole, however, the information has revealed that many disparate factors are involved in adhesion processes. Whether a particular microorganism can adhere to a certain substratum depends on the properties of the microbial strain itself and on charac teristics of the substratum and of the environment.
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Edwin H. Beachey
Publisher : Springer
Page : 486 pages
File Size : 52,6 Mb
Release : 1980-06-30
Category : Medical
ISBN : UOM:39015000283641
General concepts and principles of bacterial adherence in animals and man; Adherence of normal flora to mucosal surfaces; Bacterial adherence and the formation of dental plaques; Mechanisms of adherence of Streptococcus mutans to smooth surfaces in vitro; Structure and cell membrane-binding properties of bacterial lipoteichoic acids and their possible role in adhesion of Streptococci to eukaryotic cells; Attachment of Mycoplasma pneumoniae to respiratory epithelium; Adhesive properties of Enterobacteriaceae; The adhesive properties of Vibrio cholerae and other Vibrio species; Adherence of Neisseria gonorrhoeae and other Neisseria species to mammalian cells;Structure and cell membrane-binding properties of bacterial fimbriae: Adherence of marine micro-organisms to smooth surfaces; Microbial adherence in plants; Cell recognition systems in eukaryotic cells; Prospects for preventing the association of harmful bacteria with host mucosal surfaces.
Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 47,9 Mb
Release : 2008-10-14
Category : Technology & Engineering
ISBN : 0080920799
Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Contributions detail scientific developments in the broad areas of food science and nutrition and are intended to provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences. The latest in important information for food scientists and nutritionists Articles are peer-reviewed by a panel of respected scientists The go-to series since 1948
Author : Thisbe K. Lindhorst,Stefan Oscarson,Julie Bouckaert
Publisher : Springer Science & Business Media
Page : 194 pages
File Size : 51,8 Mb
Release : 2009-06-23
Category : Science
ISBN : 9783642013034
bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on ?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.
Author : D. Neil Granger,Elena Senchenkova
Publisher : Morgan & Claypool Publishers
Page : 99 pages
File Size : 43,6 Mb
Release : 2010
Category : Medical
ISBN : 9781615041657
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Author : Anonim
Publisher : Academic Press
Page : 620 pages
File Size : 53,6 Mb
Release : 1998-07-01
Category : Science
ISBN : 0080860567
Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control
Author : Kateryna Kon,Mahendra Rai
Publisher : Elsevier
Page : 324 pages
File Size : 45,5 Mb
Release : 2014-03-18
Category : Science
ISBN : 9780124116429
Microbiology for Surgical Infections: Diagnosis, Prognosis and Treatment explores current trends in etiology and antibiotic resistance of pathogens responsible for devastating and complex surgical infections. Clinicians and researchers report the most recent advances in diagnostic approaches to bacterial and non-bacterial surgical infections, including invasive fungal infections. Current guidelines for prophylaxis of community-acquired and nosocomial infections, complications in surgery, and improvement of diagnosis and treatment of these devastating surgical infections are also discussed. The work gives specific attention to intra-abdominal and wound infections, as well as infections in cardiac surgery and neurosurgery. Taken together, these explorations inform the work of specialists in different surgical arenas, as well as those working in microbiology. Microbiology for Surgical Infections provides a resource to those working to improve outcomes in this complicated arena by discussing prospects for future study and identifying targets for future research. Provides a multi-dimensional view of myriad topics pertinent to surgical infections, including questions of etiology, pathogenesis, host-microbial interactions, diagnosis, prognosis, treatment and prophylaxis Delivers cutting-edge commentary from eminent surgeons, microbiologists, and infectious disease specialists, with global contributions from both the developed and developing worlds Presents comprehensive research informed by the most recent technological and scientific advances in the field
Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 46,5 Mb
Release : 1999
Category : Medical
ISBN : 0879696818
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Yuehuei H. An,Richard J. Friedman
Publisher : Springer Science & Business Media
Page : 647 pages
File Size : 54,6 Mb
Release : 2000-01-21
Category : Science
ISBN : 9781592592241
Research on bacterial adhesion and its significance is a major field involving many different aspects of nature and human life, such as marine science, soil and plant ecology, most importantly, the biomedical field. The adhesion ofbacteria to the food industry, and human tissue surfaces and implanted biomaterial surfaces is an important step in the patho genesis of infection. Handbook 0/ Bacterial Adhesion: Principles, Methods, and Applications is an outgrowth of the editors' own quest for information on laboratory techniques for studying bacte rial adhesion to biomaterials, bone, and other tissues and, more importantly, a response to significant needs in the research community. This book is designed to be an experimental guide for biomedical scientists, biomaterials scientists, students, laboratory technicians, or anyone who plans to conduct bacterial adhesion studies. More specifically, it is intended for all those researchers facing the chal lenge of implant infections in such devices as orthopedic prostheses, cardiovascular devices or catheters, cerebrospinal fluid shunts or extradural catheters, thoracic or abdominal catheters, portosystemic shunts or bile stents, urological catheters or stents, plastic surgical implants, oral or maxillofacial implants, contraceptive implants, or even contact lenses. It also covers research methods for the study of bacterial adhesion to tis sues such as teeth, respiratory mucosa, intestinal mucosa, and the urinary tract. In short, it constitutes a handbook for biomechanical and bioengineering researchers and students at all levels.
Author : Michael Wilson,Brian Henderson,Rod McNab
Publisher : Cambridge University Press
Page : 698 pages
File Size : 51,9 Mb
Release : 2002-04-18
Category : Medical
ISBN : 052179689X
Introductory textbook describing the ways in which bacteria cause disease at the molecular and cellular level.
Author : Carole A Bewley
Publisher : Royal Society of Chemistry
Page : 264 pages
File Size : 51,8 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847555335
Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true for host-pathogen interactions that lead to infectious diseases; as the surfaces of cells and pathogens display complex carbohydrate structures and carbohydrate binding proteins on their surface. Protein-Carbohydrate Interactions in Infectious Disease is part of the Biomolecular Science Series and provides a comprehensive overview of the subject, with contributions from leading experts in the field. Beginning with a general introduction, subsequent sections include: Atomic basis of protein-carbohydrate interactions, Structures and roles of Pseudomonas areuginosa lectins, Protein-carbohydrate interactions in enterobacterial infections, Retrocyclins: miniature lectins with potent antiviral activity, C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates, Synthetic carbohydrate-based anti-malarial vaccines and glycobiology. With full colour throughout and an extensive bibliography this book is ideal for researchers interested in the area.