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Author : Maria-Domenica Cappellini
Publisher : Unknown
Page : 128 pages
File Size : 55,5 Mb
Release : 2008
Category : Electronic
ISBN : 9963623700
Author : David J. Weatherall,J. B. Clegg
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 53,9 Mb
Release : 2008-04-30
Category : Medical
ISBN : 9780470695944
In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.
Author : D. J. Weatherall
Publisher : Unknown
Page : 186 pages
File Size : 42,9 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015009544357
Author : Marwa Zakaria,Tamer Hassan
Publisher : BoD – Books on Demand
Page : 176 pages
File Size : 40,5 Mb
Release : 2020-09-23
Category : Medical
ISBN : 9781838805869
Beta thalassemia is a common blood disorder worldwide. Thousands of infants with beta thalassemia are born each year. This book covers most of the aspects related to this disease and greatly helps in understanding this disease and its complications. Of interest are clinical studies as well as basic and translational research reports regarding pathogenesis, genetics, diagnosis as well as standard and novel therapies. This book intends to provide the reader with a comprehensive overview of today’s practices and tomorrow’s possibilities about beta thalassemia.
Author : David Weatherall
Publisher : Oxford University Press
Page : 258 pages
File Size : 40,5 Mb
Release : 2010-08-26
Category : Medical
ISBN : 9780199565603
Presents a history of thalassemia, a genetic disorder in which the body destroys abnormally-shaped hemoglobin cells at a rate that leads to anemia.
Author : Chaim Hershko
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461505938
Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).
Author : Arthur Bozikas
Publisher : Next Chapter
Page : 297 pages
File Size : 52,8 Mb
Release : 2022-02-16
Category : Biography & Autobiography
ISBN : PKEY:6610000345533
If you ask people about their earliest memories, most will recall holidays and family parties. But for Arthur, many of his earliest memories include going with his parents to regular hospital visits and staying overnight for blood transfusions. These treatments have been a frequent part of his life since birth because he has beta-thalassemia major: a rare genetic disorder that reduces his body's ability to produce enough healthy red blood cells. When reaching adolescence, most teenagers want more freedom, independence and control in their lives. For Arthur, it was the opposite, as he discovered that his lifespan would only last up to adulthood. After becoming an adult, Arthur was waiting for his death. It was at the eleventh hour, at the age of twenty-one, when Arthur was introduced to a miracle treatment, but only after the damage of iron overload from all the blood transfusion was done to his body. Grateful to be given a chance to survive for a few more years, Arthur decided to do something with his life; to get married, buy a house and also to have children, knowing he had no prospect of any future for himself.
Author : Isam Jaber Al-Zwaini
Publisher : BoD – Books on Demand
Page : 140 pages
File Size : 44,7 Mb
Release : 2018-07-11
Category : Medical
ISBN : 9781789233667
Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.
Author : Galanello Renzo,Thalassaemia International Federation
Publisher : Unknown
Page : 190 pages
File Size : 46,9 Mb
Release : 2003
Category : Electronic
ISBN : 9963623395
Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.
Author : Martin H. Steinberg
Publisher : Cambridge University Press
Page : 883 pages
File Size : 55,5 Mb
Release : 2009-08-17
Category : Medical
ISBN : 9780521875196
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Author : Antonio Piga
Publisher : Karger Medical and Scientific Publishers
Page : 50 pages
File Size : 48,9 Mb
Release : 2023-03-22
Category : Medical
ISBN : 9783318071535
Author : Anonim
Publisher : ScholarlyEditions
Page : 61 pages
File Size : 49,8 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464906442
Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Beta Thalassemia in a concise format. The editors have built Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Beta Thalassemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : National Organization for Rare Disorders
Publisher : Lippincott Williams & Wilkins
Page : 982 pages
File Size : 40,5 Mb
Release : 2003
Category : Medical
ISBN : 0781730635
NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.
Author : Robert Wynn,Rukhmi Bhat,Paul Monagle
Publisher : Cambridge University Press
Page : 299 pages
File Size : 53,7 Mb
Release : 2017-02-16
Category : Medical
ISBN : 9781107439368
A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.
Author : Anonim
Publisher : ScholarlyEditions
Page : 47 pages
File Size : 49,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464906459
Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Beta Thalassemia in a concise format. The editors have built Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Beta Thalassemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Beta Thalassemia: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.