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Author : Maria-Domenica Cappellini
Publisher : Unknown
Page : 128 pages
File Size : 48,7 Mb
Release : 2008
Category : Electronic
ISBN : 9963623700
Author : Anonim
Publisher : Unknown
Page : 111 pages
File Size : 53,6 Mb
Release : 2000
Category : Thalassemia
ISBN : 9963623301
Author : Ali Taher,Khaled Musallam,Maria-Domenica Cappellini
Publisher : Unknown
Page : 114 pages
File Size : 47,8 Mb
Release : 2017
Category : Iron deficiency anemia
ISBN : 996371711X
Author : Chaim Hershko
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461505938
Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).
Author : Sue Pavord,Beverley Hunt
Publisher : Cambridge University Press
Page : 128 pages
File Size : 54,8 Mb
Release : 2010-04-15
Category : Medical
ISBN : 9781139487092
Obstetric hematology is a fast-growing area of medicine covering the diagnosis and management of hematological problems of pregnancy. Comprehensive in approach, The Obstetric Hematology Manual addresses the many hematological conditions that can cause serious problems in pregnancy, delivery and the post-partum period for both mother and baby. Written by a team of international authorities, this text provides up-to-date, evidence-based guidelines on best care, as well as sound advice based on the experience and opinion of experts. Where appropriate, basic principles are discussed to clarify the rationale for management, and systems and procedures for disease prevention are highlighted. Many conditions and cases are discussed, including venous thromboembolism, pre-eclampsia, anemia, thrombocytopenia and inherited disorders. This book will appeal to both trainees and practitioners in obstetrics, obstetric medicine, obstetric anesthesia and hematology. It is also an accessible text for midwives, nurses, and laboratory staff.
Author : John Porter (Hematologist),Ali Taher,Afif Mufarrij,Manolis Gavalas
Publisher : Unknown
Page : 128 pages
File Size : 43,6 Mb
Release : 2012
Category : Electronic
ISBN : 9963717004
The multi-organ pathology of the thalassaemias means that the most successful patient treatment programmes involve a number of medical staff, led by paediatricians and haematologists, but including other specialists in a multidisciplinary approach. However, this means that medical professionals not involved in such multidisciplinary groups, including primary care physicians and the staff of Accident and Emergency departments, rarely treat patients with thalassaemia. As a result, their knowledge of how to address acute complications in such patients is extremely limited. This handbook aims to provide a brief evaluation of the situations in which a thalassaemia patient may seek help beyond the specialized environment he/she is used to. The layout of the handbook is intended to enable the medical professional in a busy clinical setting to draw essential information at a glance, supporting rapid, accurate as possible, decisions on how to proceed.
Author : Isam Jaber Al-Zwaini
Publisher : BoD – Books on Demand
Page : 140 pages
File Size : 42,8 Mb
Release : 2018-07-11
Category : Medical
ISBN : 9781789233667
Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.
Author : D. J. Weatherall
Publisher : Unknown
Page : 184 pages
File Size : 43,8 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015009544357
Author : Barbara J. Bain
Publisher : John Wiley & Sons
Page : 331 pages
File Size : 49,9 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9780470994238
This unique book is written by Barbara Bain, a leadinghaematologist with a reputation for her educational prowess in thefield. It provides a concise overview of the haemoglobinopathies andfocuses on the selection, performance, and interpretation ofrelevant laboratory tests. The tests dealt with are mainly thosedone regularly in diagnostic haematology laboratories. Where morespecialist tests are required, the reader is given an overview ofwhat the specialist centre will do, with guidance on what theresult will imply. This book is extremely practical in orientation and is anessential reference volume in the haematology laboratory. Haemoglobinopathy Diagnosis is ideal for: Trainees and residents in haematology Hematologists in practice Laboratory scientists Why Buy This Book? New Edition - Fully updated, with 43 new pictures and 37 pagesof illustrated clinical cases to use for teaching andself-evaluation Essential reference volume for the haematology laboratory Focuses on diagnosis Very practical in its approach In addition to the self-assessment case studies, contains "testyour knowledge" sections at the end of every chapter Remarkably comprehensive for a compact book
Author : Kenneth Kaushansky,Marshall A. Lichtman,Josef Prchal,Marcel M. Levi,Oliver W Press,Linda J Burns,Michael Caligiuri
Publisher : McGraw Hill Professional
Page : 2528 pages
File Size : 42,9 Mb
Release : 2015-12-23
Category : Medical
ISBN : 9780071833011
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2019! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
Author : Galanello Renzo,Thalassaemia International Federation
Publisher : Unknown
Page : 190 pages
File Size : 51,9 Mb
Release : 2003
Category : Electronic
ISBN : 9963623395
Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.
Author : Anjana Munshi
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 52,7 Mb
Release : 2015-11-11
Category : Medical
ISBN : 9789535121985
The book, Inherited Hemoglobin Disorders, describes the genetic defects of hemoglobins, disease complications, and therapeutic strategies. This book has two distinct sections. The first theme includes seven chapters devoted to the types of hemoglobinopathies, mutation spectrum, diagnostic methods, and disease complications, and the second theme includes three chapters focusing on various treatment strategies. The content of the chapters presented in the book is guided by the knowledge and experience of the contributing authors. This book serves as an important resource and review to the researchers in the field of hemoglobinopathies.
Author : David J. Weatherall,J. B. Clegg
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 40,5 Mb
Release : 2008-04-30
Category : Medical
ISBN : 9780470695944
In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.
Author : National Blood Authority (Australia)
Publisher : Unknown
Page : 168 pages
File Size : 40,6 Mb
Release : 2012
Category : Health & Fitness
ISBN : 0977529878
Author : Martin H. Steinberg
Publisher : Cambridge University Press
Page : 883 pages
File Size : 53,9 Mb
Release : 2009-08-17
Category : Medical
ISBN : 9780521875196
Completely revised new edition of the definitive reference on disorders of hemoglobin.