Bioadhesion

Author : Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr
Publisher : CRC Press
Page : 704 pages
File Size : 42,5 Mb
Release : 1999-07-13
Category : Medical
ISBN : 1420001345

Get Book

Bioadhesive Drug Delivery Systems by Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr Pdf

This invaluable reference presents a comprehensive review of the basic methods for characterizing bioadhesive materials and improving vehicle targeting and uptake-offering possibilities for reformulating existing compounds to create new pharmaceuticals at lower development costs. Evaluates the unique carrier characteristics of bioadhesive polymers and their power to enhance localization of delivered agents, local bioavailability, and drug absorption and transport! Written by over 50 international experts and reflecting broad knowledge of both traditional bioadhesive strategies and novel clinical applications, Bioadhesive Drug Delivery Systems discusses mechanical and chemical bonding, polymer-mucus interactions, the effect of surface energy in bioadhesion, polymer hydration, and mucus rheology analyzes biochemical properties of mucus and glycoproteins, cell adhesion molecules, and cellular interaction with two- and three-dimensional surfaces covers microbalances and magnetic force transducers, atomic force microscopy, direct measurements of molecular level adhesions, and methods to measure cell-cell interactions examines bioadhesive carriers, diffusion or penetration enhancers, and lectin-targeted vehicles describes vaginal, nasal, buccal, ocular, and transdermal drug delivery reviews bioadhesive interactions with the mucosal tissues of the eye and mouth, and those in the respiratory, urinary, and gastrointestinal tracts explores issues of product development, clinical testing, and production and more! Amply referenced with over 1400 bibliographic citations, and illustrated with more than 300 drawings, photographs, tables, and display equations, Bioadhesive Drug Delivery Systems serves as a sound basis for innovation in bioadhesive systems and an excellent introduction to the subject. This unique reference is ideal for pharmaceutical scientists and technologists; chemical, polymer, and plastics engineers; biochemists; physical, surface, and colloid chemists; biologists; and upper-level undergraduate and graduate students in these disciplines.

Author : Vincent M. Lenaerts,Robert Gurny
Publisher : CRC Press
Page : 244 pages
File Size : 52,6 Mb
Release : 1989-11-30
Category : Medical
ISBN : 084935367X

Get Book

Bioadhesive Drug Delivery Systems by Vincent M. Lenaerts,Robert Gurny Pdf

This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is progressively released. Included in this book are descriptions of the different mucosae in healthy and pathological situations, a theoretical approach of polymers-mucin interactions, and a comparative description of the methods used to evaluate bioadhesion. Up-to-date reviews of pharmaceutical applications are also given - subdivided according to the route of administration and type of system. It also contains a chapter devoted to the fundamentals of bioadhesion. This reference is an indispensable guide for researchers in the pharmaceutical field as well as academic researchers.

Author : Havazelet Bianco-Peled,Maya Davidovich-Pinhas
Publisher : CRC Press
Page : 314 pages
File Size : 50,9 Mb
Release : 2015-03-02
Category : Medical
ISBN : 9789814463997

Get Book

Bioadhesion and Biomimetics by Havazelet Bianco-Peled,Maya Davidovich-Pinhas Pdf

Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientists—including chemists, physicists, biologists, and medical experts—materials’ producers, and manufacturers combine their knowledge. From the practical point of view, bioadhesive systems have been used for several years for medical applications such as dentistry and orthopedics and are now entering new fields, for example, tissue sealing and directed drug delivery systems. Understanding bioadhesion mechanisms is of prime importance while exploring desired adhesion for bioadhesion applications such as sealants as well as successful prevention of undesired adhesion of biomolecules, cells, or organisms. Controlling the occurrence of bioadhesion events is also an important problem in the design and use of medical devices, biosensors, membranes, ships, and oil rigs. This book provides a comprehensive view of bioadhesion and highlights different aspects of this phenomenon. The first section of the book presents fundamentals aspects of bioadhesion. It also summarizes various direct and indirect methods used to investigate and characterize bioadhesion. The second section describes studies of natural adhesives. These include "wet" adhesives that are produced and secreted by sessile marine organisms such as mussels and sand tubes and "dry" adhesives such as the one characterizing the gecko foot. The third section focuses on biomimetic adhesives. These man-made materials are fabricated on the basis of the lessons learned from nature emphasizing the correlation between nature understanding and biomimetics. Finally, the last section reviews medical applications of adhesive materials, which include surgical sealants, mucoadhesive drug delivery vehicles, and prevention of adhesion on medical devices.

Author : K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 48,5 Mb
Release : 2020-06-16
Category : Technology & Engineering
ISBN : 9781119640196

Get Book

Bioadhesives in Drug Delivery by K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang Pdf

This important and unique book comprises 12 chapters divided into three parts examining the fundamental aspects, bioadhesive formulations, and drug delivery applications. Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the delivery system to the site of interest and thus offers a useful and efficient technique for targeting a drug to the desired location for a prolonged duration. This book addresses the various relevant aspects of bioadhesives in drug delivery in an easily accessible and unified manner. The book containing 12 chapters written by eminent researchers from many parts of the globe is divided into three parts: Part 1: Fundamental Aspects; Part 2: Bioadhesive Formulations; Part 3: Drug Delivery Applications. The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; bioadhesive hydrogels and applications; ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.

Author : Stanislav N. Gorb,Ken Nakano
Publisher : Frontiers Media SA
Page : 163 pages
File Size : 43,8 Mb
Release : 2021-11-01
Category : Technology & Engineering
ISBN : 9782889714209

Get Book

Bioadhesion by Stanislav N. Gorb,Ken Nakano Pdf

Author : Peter J. Tarcha
Publisher : CRC Press
Page : 298 pages
File Size : 42,5 Mb
Release : 2023-06-14
Category : Medical
ISBN : 9781000941111

Get Book

Polymers for Controlled Drug Delivery by Peter J. Tarcha Pdf

Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.

Author : Severian Dumitriu
Publisher : CRC Press
Page : 1192 pages
File Size : 40,8 Mb
Release : 2001-11-29
Category : Science
ISBN : 0203904672

Get Book

Polymeric Biomaterials, Revised and Expanded by Severian Dumitriu Pdf

Offering nearly 7000 references-3900 more than the first edition-Polymeric Biomaterials, Second Edition is an up-to-the-minute source for plastics and biomedical engineers, polymer scientists, biochemists, molecular biologists, macromolecular chemists, pharmacists, cardiovascular and plastic surgeons, and graduate and medical students in these disciplines. Completely revised and updated, it includes coverage of genetic engineering, synthesis of biodegradable polymers, hydrogels, and mucoadhesive polymers, as well as polymers for dermacosmetic treatments, burn and wound dressings, orthopedic surgery, artificial joints, vascular prostheses, and in blood contacting systems.

Author : Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
Publisher : John Wiley & Sons
Page : 304 pages
File Size : 43,6 Mb
Release : 2020-06-03
Category : Science
ISBN : 9781119655046

Get Book

Green Adhesives by Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri Pdf

Green Adhesives: Preparation, Properties and Applications deals with the fabrication methods, characterization, and applications of green adhesives. It also includes the collective properties of waterborne, bio, and wound-healing green adhesives. Exclusive attention is devoted to discussing the applications of green adhesives in biomedical coatings, food, and industrial applications.

Author : Robert Gurny,Hans E. Junginger
Publisher : Medpharm Scientific Publishers
Page : 224 pages
File Size : 43,6 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015017721310

Get Book

Bioadhesion by Robert Gurny,Hans E. Junginger Pdf

Author : G. Buckton
Publisher : CRC Press
Page : 320 pages
File Size : 52,9 Mb
Release : 2000-02-11
Category : Medical
ISBN : 3718656337

Get Book

Interfacial Phenomena in Drug Delivery and Targeting by G. Buckton Pdf

This book series aims to provide a comprehensive survey for senior undergraduates, graduates and established workers carrying out research in drug delivery and targeting in its many facets.

Author : Tapan Kumar Giri,Bijaya Ghosh,Hemant Badwaik
Publisher : Elsevier
Page : 312 pages
File Size : 53,6 Mb
Release : 2023-09-15
Category : Science
ISBN : 9780323957946

Get Book

Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine by Tapan Kumar Giri,Bijaya Ghosh,Hemant Badwaik Pdf

Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine is an archival reference for researchers, students and scientists working on hydrogels based on microbial and animal sources. The book contains Information regarding their synthesis, characterization, and applications in the field of drug delivery and regenerative medicine. Each chapter addresses a separate polysaccharide hydrogel and its suitability in drug delivery and/or regenerative medicine. This is a novel resource that brings together a panel of highly accomplished experts in the field of natural polysaccharides to discuss basic causes and specific problems related to drug delivery and regenerative medicine. Presents detailed practical and theoretical concepts Includes fundamentals and methodologies for hydrogel preparation Covers all hydrogels and specific applications in the field of drug delivery and tissue engineering

Author : Vivek Dave,Nikita Gupta,Srija Sur
Publisher : John Wiley & Sons
Page : 467 pages
File Size : 47,5 Mb
Release : 2020-12-29
Category : Computers
ISBN : 9781119711681

Get Book

Nanopharmaceutical Advanced Delivery Systems by Vivek Dave,Nikita Gupta,Srija Sur Pdf

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Author : Ferdyansyah Mahyudin,Hendra Hermawan
Publisher : Springer
Page : 242 pages
File Size : 46,5 Mb
Release : 2016-02-26
Category : Technology & Engineering
ISBN : 9783319148458

Get Book

Biomaterials and Medical Devices by Ferdyansyah Mahyudin,Hendra Hermawan Pdf

This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.

Author : Janek Byern,Ingo Grunwald
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 54,7 Mb
Release : 2011-01-27
Category : Technology & Engineering
ISBN : 9783709102862

Get Book

Biological Adhesive Systems by Janek Byern,Ingo Grunwald Pdf

J. Herbert Waite Like many graduate students before and after me I was There are so many species about which nothing is known, mesmerized by a proposition expressed years earlier by and the curse of not knowing is apathy. Krogh (1929) – namely that “for many problems there is Bioadhesion is the adaptation featured in this book, an animal on which it can be most conveniently studied”. and biology has many adhesive practitioners. Indeed, This opinion became known as the August Krogh Prin- every living organism is adhesively assembled in the ciple and remains much discussed to this day, particu- most exquisite way. Clearly, speci? c adhesion needs to larly among comparative physiologists (Krebs, 1975). be distinguished from the opportunistic variety. I think The words “problems” and “animal” are key because of speci? c adhesion as the adhesion between cells in the they highlight the two fundamental and complementary same tissue, whereas opportunistic adhesion might be the foci of biological research: (1) expertise about an animal adhesion between pathogenic microbes and the urinary (zoo-centric), which is mostly observational and (2) a tract, or between a slug and the garden path. If oppor- mechanistic analysis of some problem in the animal’s life nistic bioadhesion is our theme, then there are still many history or physiology (problem-centric), which is usually practitioners but the subset is somewhat more select than a hypothesis-driven investigation. before.

Author : Nimit Worakul
Publisher : Unknown
Page : 158 pages
File Size : 51,5 Mb
Release : 2001
Category : Colloids
ISBN : WISC:89078143039

Get Book

Mechanistic Studies of Bioadhesion by Nimit Worakul Pdf