Bioadhesive Drug Delivery Systems

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Bioadhesive Drug Delivery Systems

Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr
Bioadhesive Drug Delivery Systems Book PDF

Author : Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr
Publisher : CRC Press
Page : 704 pages
File Size : 55,7 Mb
Release : 1999-07-13
Category : Medical
ISBN : 1420001345

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Bioadhesive Drug Delivery Systems by Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr Pdf

This invaluable reference presents a comprehensive review of the basic methods for characterizing bioadhesive materials and improving vehicle targeting and uptake-offering possibilities for reformulating existing compounds to create new pharmaceuticals at lower development costs. Evaluates the unique carrier characteristics of bioadhesive polymers and their power to enhance localization of delivered agents, local bioavailability, and drug absorption and transport! Written by over 50 international experts and reflecting broad knowledge of both traditional bioadhesive strategies and novel clinical applications, Bioadhesive Drug Delivery Systems discusses mechanical and chemical bonding, polymer-mucus interactions, the effect of surface energy in bioadhesion, polymer hydration, and mucus rheology analyzes biochemical properties of mucus and glycoproteins, cell adhesion molecules, and cellular interaction with two- and three-dimensional surfaces covers microbalances and magnetic force transducers, atomic force microscopy, direct measurements of molecular level adhesions, and methods to measure cell-cell interactions examines bioadhesive carriers, diffusion or penetration enhancers, and lectin-targeted vehicles describes vaginal, nasal, buccal, ocular, and transdermal drug delivery reviews bioadhesive interactions with the mucosal tissues of the eye and mouth, and those in the respiratory, urinary, and gastrointestinal tracts explores issues of product development, clinical testing, and production and more! Amply referenced with over 1400 bibliographic citations, and illustrated with more than 300 drawings, photographs, tables, and display equations, Bioadhesive Drug Delivery Systems serves as a sound basis for innovation in bioadhesive systems and an excellent introduction to the subject. This unique reference is ideal for pharmaceutical scientists and technologists; chemical, polymer, and plastics engineers; biochemists; physical, surface, and colloid chemists; biologists; and upper-level undergraduate and graduate students in these disciplines.

Bioadhesives in Drug Delivery

K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang
Bioadhesives in Drug Delivery Book PDF

Author : K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 47,9 Mb
Release : 2020-05-26
Category : Technology & Engineering
ISBN : 9781119640264

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Bioadhesives in Drug Delivery by K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang Pdf

This important and unique book comprises 12 chapters divided into three parts examining the fundamental aspects, bioadhesive formulations, and drug delivery applications. Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the delivery system to the site of interest and thus offers a useful and efficient technique for targeting a drug to the desired location for a prolonged duration. This book addresses the various relevant aspects of bioadhesives in drug delivery in an easily accessible and unified manner. The book containing 12 chapters written by eminent researchers from many parts of the globe is divided into three parts: Part 1: Fundamental Aspects; Part 2: Bioadhesive Formulations; Part 3: Drug Delivery Applications. The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; bioadhesive hydrogels and applications; ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.

Bioadhesive Drug Delivery Systems

Vincent M. Lenaerts,Robert Gurny
Bioadhesive Drug Delivery Systems Book PDF

Author : Vincent M. Lenaerts,Robert Gurny
Publisher : CRC Press
Page : 244 pages
File Size : 55,9 Mb
Release : 1989-11-30
Category : Medical
ISBN : 084935367X

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Bioadhesive Drug Delivery Systems by Vincent M. Lenaerts,Robert Gurny Pdf

This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is progressively released. Included in this book are descriptions of the different mucosae in healthy and pathological situations, a theoretical approach of polymers-mucin interactions, and a comparative description of the methods used to evaluate bioadhesion. Up-to-date reviews of pharmaceutical applications are also given - subdivided according to the route of administration and type of system. It also contains a chapter devoted to the fundamentals of bioadhesion. This reference is an indispensable guide for researchers in the pharmaceutical field as well as academic researchers.

Mucoadhesive Materials and Drug Delivery Systems

Vitaliy V. Khutoryanskiy
Mucoadhesive Materials and Drug Delivery Systems Book PDF

Author : Vitaliy V. Khutoryanskiy
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 55,9 Mb
Release : 2014-06-12
Category : Science
ISBN : 9781118794395

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Mucoadhesive Materials and Drug Delivery Systems by Vitaliy V. Khutoryanskiy Pdf

Mucoadhesion defined as attachment of synthetic or natural materials to mucosal tissues has been widely exploited in pharmaceutical forms. This multi-author book provides an up-to-date account of current research on mucoadhesive materials and drug delivery systems. The introductory section describes the structure and physiology of various mucosal surfaces (oral, nasal, ocular, gastrointestinal and vaginal mucosa). This is followed by chapters on the various methods used to study mucoadhesion and to characterise mucoadhesive properties of various dosage forms. The final section will summarise information on traditional and novel types of mucoadhesive materials, such as chitosan, thiomers, and liposome-based formulations. This book is unique as there is currently no modern book considering mucoadhesion - all other existing books on the topic are either narrowly focused or more than 10 years old. Furthermore, each contributor offers specialist perspectives from a variety of global locations in both industrial and academic research centres.

Nanopharmaceutical Advanced Delivery Systems

Vivek Dave,Nikita Gupta,Srija Sur
Nanopharmaceutical Advanced Delivery Systems Book PDF

Author : Vivek Dave,Nikita Gupta,Srija Sur
Publisher : John Wiley & Sons
Page : 467 pages
File Size : 44,7 Mb
Release : 2020-12-29
Category : Computers
ISBN : 9781119711681

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Nanopharmaceutical Advanced Delivery Systems by Vivek Dave,Nikita Gupta,Srija Sur Pdf

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes Book PDF

Author : Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
Publisher : Academic Press
Page : 552 pages
File Size : 47,8 Mb
Release : 2017-05-23
Category : Medical
ISBN : 9780128097182

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Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes by Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer Pdf

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Chitosan in Drug Delivery

Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Chitosan in Drug Delivery Book PDF

Author : Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Publisher : Academic Press
Page : 557 pages
File Size : 51,6 Mb
Release : 2021-10-26
Category : Medical
ISBN : 9780128193372

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Chitosan in Drug Delivery by Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak Pdf

Chitosan in Drug Delivery provides thorough insights into chitosan chemistry, collection, chemical modifications, characterization and applications in the pharmaceutical industry and healthcare fields. The book explores molecular weight, degree of deacetylation and molecular geometry, emphasizing recent advances in the field as written by academic, industry and regulatory scientists. It will be a useful resource for pharmaceutical scientists, including industrial pharmacists, analytical scientists, postgraduate students, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development in natural polymers containing drug delivery. Provides methodologies for the design, development and selection of chitosan in drug delivery for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of chitosan Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan

Recent Advances in Novel Drug Carrier Systems

Ali Demir Sezer
Recent Advances in Novel Drug Carrier Systems Book PDF

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Page : 516 pages
File Size : 41,9 Mb
Release : 2012-10-31
Category : Medical
ISBN : 9789535108108

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Recent Advances in Novel Drug Carrier Systems by Ali Demir Sezer Pdf

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Herbal Bioactive-Based Drug Delivery Systems

Inderbir Singh Bakshi,Rajni Bala,Reecha Madaan,Rakesh K. Sindhu
Herbal Bioactive Based Drug Delivery Systems Book PDF

Author : Inderbir Singh Bakshi,Rajni Bala,Reecha Madaan,Rakesh K. Sindhu
Publisher : Academic Press
Page : 495 pages
File Size : 49,9 Mb
Release : 2022-03-13
Category : Business & Economics
ISBN : 9780323859103

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Herbal Bioactive-Based Drug Delivery Systems by Inderbir Singh Bakshi,Rajni Bala,Reecha Madaan,Rakesh K. Sindhu Pdf

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments. Explores standardization, regulation and enhancement issues in herbal bioactives Discusses novel developments, herbal cosmetics and toxicity/interaction issues Provides a comprehensive reference on all aspects of herbal bioactives

Fundamentals of Drug Delivery

Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Fundamentals of Drug Delivery Book PDF

Author : Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang
Publisher : John Wiley & Sons
Page : 580 pages
File Size : 46,9 Mb
Release : 2021-10-12
Category : Medical
ISBN : 9781119769606

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Fundamentals of Drug Delivery by Heather A. E. Benson,Michael S. Roberts,Adrian C. Williams,Xiaowen Liang Pdf

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Bioadhesion and Biomimetics

Havazelet Bianco-Peled,Maya Davidovich-Pinhas
Bioadhesion and Biomimetics Book PDF

Author : Havazelet Bianco-Peled,Maya Davidovich-Pinhas
Publisher : CRC Press
Page : 314 pages
File Size : 48,6 Mb
Release : 2015-03-02
Category : Medical
ISBN : 9789814463997

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Bioadhesion and Biomimetics by Havazelet Bianco-Peled,Maya Davidovich-Pinhas Pdf

Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientists—including chemists, physicists, biologists, and medical experts—materials’ producers, and manufacturers combine their knowledge. From the practical point of view, bioadhesive systems have been used for several years for medical applications such as dentistry and orthopedics and are now entering new fields, for example, tissue sealing and directed drug delivery systems. Understanding bioadhesion mechanisms is of prime importance while exploring desired adhesion for bioadhesion applications such as sealants as well as successful prevention of undesired adhesion of biomolecules, cells, or organisms. Controlling the occurrence of bioadhesion events is also an important problem in the design and use of medical devices, biosensors, membranes, ships, and oil rigs. This book provides a comprehensive view of bioadhesion and highlights different aspects of this phenomenon. The first section of the book presents fundamentals aspects of bioadhesion. It also summarizes various direct and indirect methods used to investigate and characterize bioadhesion. The second section describes studies of natural adhesives. These include "wet" adhesives that are produced and secreted by sessile marine organisms such as mussels and sand tubes and "dry" adhesives such as the one characterizing the gecko foot. The third section focuses on biomimetic adhesives. These man-made materials are fabricated on the basis of the lessons learned from nature emphasizing the correlation between nature understanding and biomimetics. Finally, the last section reviews medical applications of adhesive materials, which include surgical sealants, mucoadhesive drug delivery vehicles, and prevention of adhesion on medical devices.

Novel Drug Delivery Systems and Regulatory Affairs

Sudhakar Yajaman & Jayaveera K.N.
Novel Drug Delivery Systems and Regulatory Affairs Book PDF

Author : Sudhakar Yajaman & Jayaveera K.N.
Publisher : S. Chand Publishing
Page : 128 pages
File Size : 44,5 Mb
Release : 2014
Category : Medical
ISBN : 9788121942577

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Novel Drug Delivery Systems and Regulatory Affairs by Sudhakar Yajaman & Jayaveera K.N. Pdf

Novel Drug Delivery Systems | Transdermal Drug Delivery Systems | Mucoadhesive Drug Delivery Systems | Targeted Drugdelivery Systems | Regulatory Agencies | Quality Assurance | Good Manufacturing Practices | Validation

Green Adhesives

Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
Green Adhesives Book PDF

Author : Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
Publisher : John Wiley & Sons
Page : 304 pages
File Size : 55,7 Mb
Release : 2020-06-03
Category : Science
ISBN : 9781119655046

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Green Adhesives by Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri Pdf

Green Adhesives: Preparation, Properties and Applications deals with the fabrication methods, characterization, and applications of green adhesives. It also includes the collective properties of waterborne, bio, and wound-healing green adhesives. Exclusive attention is devoted to discussing the applications of green adhesives in biomedical coatings, food, and industrial applications.

Advances in Drug Delivery Systems, 6

James M. Anderson,Sung Wan Kim,Jindrich Kopeček
Advances in Drug Delivery Systems 6 Book PDF

Author : James M. Anderson,Sung Wan Kim,Jindrich Kopeček
Publisher : Elsevier
Page : 372 pages
File Size : 41,9 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483161570

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Advances in Drug Delivery Systems, 6 by James M. Anderson,Sung Wan Kim,Jindrich Kopeček Pdf

Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology. The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes. The book examines the factors on in vitro micelle stability of adriamycin-block copolymer conjugates; vaginal and reproductive system treatments using a bioadhesive polymer; and control of the disposition profiles of proteins in the kidney via chemical modification. The publication also takes a look at drug delivery using biodegradable microspheres; approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer; and biodegradable microspheres for the delivery of oral vaccines. The selection is a valuable source material for scientists and readers interested in the advances in the systems of drug delivery.

Strategies to Modify the Drug Release from Pharmaceutical Systems

Marcos Luciano Bruschi
Strategies to Modify the Drug Release from Pharmaceutical Systems Book PDF

Author : Marcos Luciano Bruschi
Publisher : Woodhead Publishing
Page : 208 pages
File Size : 44,9 Mb
Release : 2015-06-16
Category : Medical
ISBN : 9780081001127

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Strategies to Modify the Drug Release from Pharmaceutical Systems by Marcos Luciano Bruschi Pdf

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications