Bioinformatics Challenges At The Interface Of Biology And Computer Science

Author : Teresa K. Attwood,Stephen R. Pettifer,David Thorne
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 40,5 Mb
Release : 2016-10-03
Category : Science
ISBN : 9780470035504

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Bioinformatics Challenges at the Interface of Biology and Computer Science by Teresa K. Attwood,Stephen R. Pettifer,David Thorne Pdf

This innovative book provides a completely fresh exploration of bioinformatics, investigating its complex interrelationship with biology and computer science. It approaches bioinformatics from a unique perspective, highlighting interdisciplinary gaps that often trap the unwary. The book considers how the need for biological databases drove the evolution of bioinformatics; it reviews bioinformatics basics (including database formats, data-types and current analysis methods), and examines key topics in computer science (including data-structures, identifiers and algorithms), reflecting on their use and abuse in bioinformatics. Bringing these disciplines together, this book is an essential read for those who wish to better understand the challenges for bioinformatics at the interface of biology and computer science, and how to bridge the gaps. It will be an invaluable resource for advanced undergraduate and postgraduate students, and for lecturers, researchers and professionals with an interest in this fascinating, fast-moving discipline and the knotty problems that surround it.

Author : Teresa K. Attwood,Stephen R. Pettifer,David Thorne
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 54,8 Mb
Release : 2016-09-26
Category : Science
ISBN : 9780470035481

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Bioinformatics Challenges at the Interface of Biology and Computer Science by Teresa K. Attwood,Stephen R. Pettifer,David Thorne Pdf

This innovative book provides a completely fresh exploration of bioinformatics, investigating its complex interrelationship with biology and computer science. It approaches bioinformatics from a unique perspective, highlighting interdisciplinary gaps that often trap the unwary. The book considers how the need for biological databases drove the evolution of bioinformatics; it reviews bioinformatics basics (including database formats, data-types and current analysis methods), and examines key topics in computer science (including data-structures, identifiers and algorithms), reflecting on their use and abuse in bioinformatics. Bringing these disciplines together, this book is an essential read for those who wish to better understand the challenges for bioinformatics at the interface of biology and computer science, and how to bridge the gaps. It will be an invaluable resource for advanced undergraduate and postgraduate students, and for lecturers, researchers and professionals with an interest in this fascinating, fast-moving discipline and the knotty problems that surround it.

Author : National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Frontiers at the Interface of Computing and Biology
Publisher : National Academies Press
Page : 469 pages
File Size : 50,6 Mb
Release : 2006-01-01
Category : Science
ISBN : 9780309096126

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Catalyzing Inquiry at the Interface of Computing and Biology by National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Frontiers at the Interface of Computing and Biology Pdf

Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

Author : Bryan P. Bergeron
Publisher : Prentice Hall Professional
Page : 472 pages
File Size : 51,9 Mb
Release : 2003
Category : Computers
ISBN : 0131008250

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Bioinformatics Computing by Bryan P. Bergeron Pdf

Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level.

Author : Zoé Lacroix,Terence Critchlow
Publisher : Academic Press
Page : 466 pages
File Size : 49,6 Mb
Release : 2003-07-18
Category : Computers
ISBN : 9781558608290

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Bioinformatics by Zoé Lacroix,Terence Critchlow Pdf

The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable. * Provides a clear overview of the state-of-the-art in data integration and interoperability in genomics, highlighting a variety of systems and giving insight into the strengths and weaknesses of their different approaches.-

Author : Albert Y. Zomaya
Publisher : John Wiley & Sons
Page : 814 pages
File Size : 43,5 Mb
Release : 2006-04-14
Category : Computers
ISBN : 9780471756491

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Parallel Computing for Bioinformatics and Computational Biology by Albert Y. Zomaya Pdf

Discover how to streamline complex bioinformatics applications with parallel computing This publication enables readers to handle more complex bioinformatics applications and larger and richer data sets. As the editor clearly shows, using powerful parallel computing tools can lead to significant breakthroughs in deciphering genomes, understanding genetic disease, designing customized drug therapies, and understanding evolution. A broad range of bioinformatics applications is covered with demonstrations on how each one can be parallelized to improve performance and gain faster rates of computation. Current parallel computing techniques and technologies are examined, including distributed computing and grid computing. Readers are provided with a mixture of algorithms, experiments, and simulations that provide not only qualitative but also quantitative insights into the dynamic field of bioinformatics. Parallel Computing for Bioinformatics and Computational Biology is a contributed work that serves as a repository of case studies, collectively demonstrating how parallel computing streamlines difficult problems in bioinformatics and produces better results. Each of the chapters is authored by an established expert in the field and carefully edited to ensure a consistent approach and high standard throughout the publication. The work is organized into five parts: * Algorithms and models * Sequence analysis and microarrays * Phylogenetics * Protein folding * Platforms and enabling technologies Researchers, educators, and students in the field of bioinformatics will discover how high-performance computing can enable them to handle more complex data sets, gain deeper insights, and make new discoveries.

Author : Stephen Misener,Stephen A. Krawetz
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 43,9 Mb
Release : 2008-02-02
Category : Science
ISBN : 9781592591923

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Bioinformatics Methods and Protocols by Stephen Misener,Stephen A. Krawetz Pdf

Computers have become an essential component of modern biology. They help to manage the vast and increasing amount of biological data and continue to play an integral role in the discovery of new biological relationships. This in silico approach to biology has helped to reshape the modern biological sciences. With the biological revolution now among us, it is imperative that each scientist develop and hone today’s bioinformatics skills, if only at a rudimentary level. Bioinformatics Methods and Protocols was conceived as part of the Methods in Molecular Biology series to meet this challenge and to provide the experienced user with useful tips and an up-to-date overview of current developments. It builds upon the foundation that was provided in the two-volume set published in 1994 entitled Computer Analysis of Sequence Data. We divided Bioinformatics Methods and Protocols into five parts, including a thorough survey of the basic sequence analysis software packages that are available at most institutions, as well as the design and implemen- tion of an essential introductory Bioinformatics course. In addition, we included sections describing specialized noncommercial software, databases, and other resources available as part of the World Wide Web and a stimul- ing discussion of some of the computational challenges biologists now face and likely future solutions.

Author : Matthew He,Sergey Petoukhov
Publisher : John Wiley & Sons
Page : 231 pages
File Size : 43,5 Mb
Release : 2011-03-16
Category : Computers
ISBN : 9781118099520

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Mathematics of Bioinformatics by Matthew He,Sergey Petoukhov Pdf

Mathematics of Bioinformatics: Theory, Methods, and Applications provides a comprehensive format for connecting and integrating information derived from mathematical methods and applying it to the understanding of biological sequences, structures, and networks. Each chapter is divided into a number of sections based on the bioinformatics topics and related mathematical theory and methods. Each topic of the section is comprised of the following three parts: an introduction to the biological problems in bioinformatics; a presentation of relevant topics of mathematical theory and methods to the bioinformatics problems introduced in the first part; an integrative overview that draws the connections and interfaces between bioinformatics problems/issues and mathematical theory/methods/applications.

Author : Pavel Pevzner,Ron Shamir
Publisher : Cambridge University Press
Page : 478 pages
File Size : 48,9 Mb
Release : 2011-09-15
Category : Science
ISBN : 9781139501613

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Bioinformatics for Biologists by Pavel Pevzner,Ron Shamir Pdf

The computational education of biologists is changing to prepare students for facing the complex datasets of today's life science research. In this concise textbook, the authors' fresh pedagogical approaches lead biology students from first principles towards computational thinking. A team of renowned bioinformaticians take innovative routes to introduce computational ideas in the context of real biological problems. Intuitive explanations promote deep understanding, using little mathematical formalism. Self-contained chapters show how computational procedures are developed and applied to central topics in bioinformatics and genomics, such as the genetic basis of disease, genome evolution or the tree of life concept. Using bioinformatic resources requires a basic understanding of what bioinformatics is and what it can do. Rather than just presenting tools, the authors - each a leading scientist - engage the students' problem-solving skills, preparing them to meet the computational challenges of their life science careers.

Author : Gautam B. Singh
Publisher : Springer
Page : 345 pages
File Size : 47,7 Mb
Release : 2014-09-24
Category : Technology & Engineering
ISBN : 9783319114033

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Fundamentals of Bioinformatics and Computational Biology by Gautam B. Singh Pdf

This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolboxTM. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.

Author : Anonim
Publisher : National Academies Press
Page : 59 pages
File Size : 47,6 Mb
Release : 2005
Category : Science
ISBN : 9780309100298

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Frontiers of Bioinformatics by Anonim Pdf

Author : Miguel Rocha,Florentino Fdez-Riverola,Mohd Saberi Mohamad,Roberto Casado-Vara
Publisher : Springer Nature
Page : 188 pages
File Size : 50,7 Mb
Release : 2021-08-27
Category : Technology & Engineering
ISBN : 9783030862589

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Practical Applications of Computational Biology & Bioinformatics, 15th International Conference (PACBB 2021) by Miguel Rocha,Florentino Fdez-Riverola,Mohd Saberi Mohamad,Roberto Casado-Vara Pdf

This book features novel research papers spanning many different subfields in bioinformatics and computational biology, presenting the latest research on the practical applications to promote fruitful interactions between young researchers in different areas related to the field. Clearly, biology is increasingly becoming a science of information, requiring tools from the computational sciences. To address these challenges, we have seen the emergence of a new generation of interdisciplinary scientists with a strong background in the biological and computational sciences. PACBB'21 expects to contribute to this effort by encouraging a successful collaboration of researchers in different areas related to bioinformatics. The PACBB'21 technical program included 17 papers covering many different subfields in bioinformatics and computational biology. Therefore, this conference, held in Salamanca (Spain), definitely promotes the collaboration of scientists from different research groups and with different backgrounds (computer scientists, mathematicians, biologists) to reach breakthrough solutions for these challenges.

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 54,9 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Author : Stephen A. Krawetz,David D. Womble
Publisher : Springer Science & Business Media
Page : 776 pages
File Size : 50,9 Mb
Release : 2003-01-31
Category : Computers
ISBN : 1588290646

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Introduction to Bioinformatics by Stephen A. Krawetz,David D. Womble Pdf

CD-ROM contains: chapter illustrations -- full and trial versions of programs.

Author : Corrado Priami,Emanuela Merelli,Pedro Pablo Gonzalez,Andrea Omicini
Publisher : Springer Science & Business Media
Page : 177 pages
File Size : 40,9 Mb
Release : 2005-12-12
Category : Computers
ISBN : 9783540308836

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Transactions on Computational Systems Biology III by Corrado Priami,Emanuela Merelli,Pedro Pablo Gonzalez,Andrea Omicini Pdf

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems-oriented point of view of biological phenomena. This, the third Transactions on Computational Systems Biology volume, edited by Emanuela Merelli, Pedro Pablo Gonzalez and Andrea Omicini, is devoted to considerably extended versions of selected papers presented at the International Workshop on Network Tools and Applications in Biology (NETTAB 2004), held at the University of Camerino, in Camerino, Italy, in September 2004. Dedicated especially to models and metaphors from biology to bioinformatics tools, the 10 papers selected for the special issue cover a wide range of bioinformatics research such as data visualisation, protein/RNA structure prediction, motif finding, modelling and simulation of protein interaction, genetic linkage analysis, and notations and models for systems biology.