Catalyzing Inquiry At The Interface Of Computing And Biology

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Catalyzing Inquiry at the Interface of Computing and Biology

National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Frontiers at the Interface of Computing and Biology
Catalyzing Inquiry at the Interface of Computing and Biology Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Frontiers at the Interface of Computing and Biology
Publisher : National Academies Press
Page : 469 pages
File Size : 53,9 Mb
Release : 2006-01-01
Category : Science
ISBN : 9780309096126

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Catalyzing Inquiry at the Interface of Computing and Biology by National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Frontiers at the Interface of Computing and Biology Pdf

Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

The Role of Theory in Advancing 21st-Century Biology

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century
The Role of Theory in Advancing 21st Century Biology Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century
Publisher : National Academies Press
Page : 208 pages
File Size : 53,6 Mb
Release : 2008-01-22
Category : Science
ISBN : 9780309134170

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The Role of Theory in Advancing 21st-Century Biology by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century Pdf

Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.

Positioning Synthetic Biology to Meet the Challenges of the 21st Century

National Research Council,National Academy of Engineering,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Technology, and Law
Positioning Synthetic Biology to Meet the Challenges of the 21st Century Book PDF

Author : National Research Council,National Academy of Engineering,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Technology, and Law
Publisher : National Academies Press
Page : 80 pages
File Size : 51,7 Mb
Release : 2013-08-05
Category : Science
ISBN : 9780309225861

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Positioning Synthetic Biology to Meet the Challenges of the 21st Century by National Research Council,National Academy of Engineering,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Technology, and Law Pdf

Synthetic biology -- unlike any research discipline that precedes it -- has the potential to bypass the less predictable process of evolution to usher in a new and dynamic way of working with living systems. Ultimately, synthetic biologists hope to design and build engineered biological systems with capabilities that do not exist in natural systems -- capabilities that may ultimately be used for applications in manufacturing, food production, and global health. Importantly, synthetic biology represents an area of science and engineering that raises technical, ethical, regulatory, security, biosafety, intellectual property, and other issues that will be resolved differently in different parts of the world. As a better understanding of the global synthetic biology landscape could lead to tremendous benefits, six academies -- the United Kingdom's Royal Society and Royal Academy of Engineering, the United States' National Academy of Sciences and National Academy of Engineering, and the Chinese Academy of Science and Chinese Academy of Engineering -- organized a series of international symposia on the scientific, technical, and policy issues associated with synthetic biology. Positioning Synthetic Biology to Meet the Challenges of the 21st Century summarizes the symposia proceedings.

Computational Technology for Effective Health Care

National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Engaging the Computer Science Research Community in Health Care Informatics
Computational Technology for Effective Health Care Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Engaging the Computer Science Research Community in Health Care Informatics
Publisher : National Academies Press
Page : 121 pages
File Size : 48,5 Mb
Release : 2009-02-24
Category : Computers
ISBN : 9780309155847

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Computational Technology for Effective Health Care by National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Engaging the Computer Science Research Community in Health Care Informatics Pdf

Despite a strong commitment to delivering quality health care, persistent problems involving medical errors and ineffective treatment continue to plague the industry. Many of these problems are the consequence of poor information and technology (IT) capabilities, and most importantly, the lack cognitive IT support. Clinicians spend a great deal of time sifting through large amounts of raw data, when, ideally, IT systems would place raw data into context with current medical knowledge to provide clinicians with computer models that depict the health status of the patient. Computational Technology for Effective Health Care advocates re-balancing the portfolio of investments in health care IT to place a greater emphasis on providing cognitive support for health care providers, patients, and family caregivers; observing proven principles for success in designing and implementing IT; and accelerating research related to health care in the computer and social sciences and in health/biomedical informatics. Health care professionals, patient safety advocates, as well as IT specialists and engineers, will find this book a useful tool in preparation for crossing the health care IT chasm.

Mathematics and 21st Century Biology

National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on Mathematical Sciences Research for DOE's Computational Biology
Mathematics and 21st Century Biology Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on Mathematical Sciences Research for DOE's Computational Biology
Publisher : National Academies Press
Page : 163 pages
File Size : 43,8 Mb
Release : 2005-07-16
Category : Science
ISBN : 9780309095846

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Mathematics and 21st Century Biology by National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on Mathematical Sciences Research for DOE's Computational Biology Pdf

The exponentially increasing amounts of biological data along with comparable advances in computing power are making possible the construction of quantitative, predictive biological systems models. This development could revolutionize those biology-based fields of science. To assist this transformation, the U.S. Department of Energy asked the National Research Council to recommend mathematical research activities to enable more effective use of the large amounts of existing genomic information and the structural and functional genomic information being created. The resulting study is a broad, scientifically based view of the opportunities lying at the mathematical science and biology interface. The book provides a review of past successes, an examination of opportunities at the various levels of biological systemsâ€" from molecules to ecosystemsâ€"an analysis of cross-cutting themes, and a set of recommendations to advance the mathematics-biology connection that are applicable to all agencies funding research in this area.

Encyclopedia of Biology

Don Rittner,Timothy Lee McCabe
Encyclopedia of Biology Book PDF

Author : Don Rittner,Timothy Lee McCabe
Publisher : Infobase Publishing
Page : 417 pages
File Size : 46,7 Mb
Release : 2004-08
Category : Biology
ISBN : 9781438109992

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Encyclopedia of Biology by Don Rittner,Timothy Lee McCabe Pdf

Contains approximately 800 alphabetical entries, prose essays on important topics, line illustrations, and black-and-white photographs.

Computational Methods in Molecular Biology

S.L. Salzberg,D.B. Searls,S. Kasif
Computational Methods in Molecular Biology Book PDF

Author : S.L. Salzberg,D.B. Searls,S. Kasif
Publisher : Elsevier
Page : 368 pages
File Size : 49,9 Mb
Release : 1998-06-19
Category : Computers
ISBN : 0080860931

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Computational Methods in Molecular Biology by S.L. Salzberg,D.B. Searls,S. Kasif Pdf

Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities. This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms. The primary audience for this volume are molecular biologists working either in biotechnology companies or academic research environments, individual researchers and the institutions they work for, and students. Any biologist who relies on computers should want this book. A secondary audience will be computer scientists developing techniques with applications in biology. An excellent reference for leading techniques, it will also help introduce computer scientists to the biology problems. This is an outstanding work which will be ideal for the increasing number of scientists moving into computational biology.

Evolution of Translational Omics

Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Evolution of Translational Omics Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Publisher : National Academies Press
Page : 354 pages
File Size : 40,8 Mb
Release : 2012-09-13
Category : Science
ISBN : 9780309224185

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Evolution of Translational Omics by Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials Pdf

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Convergence

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Key Challenge Areas for Convergence and Health
Convergence Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Key Challenge Areas for Convergence and Health
Publisher : National Academies Press
Page : 152 pages
File Size : 44,6 Mb
Release : 2014-06-16
Category : Political Science
ISBN : 9780309301640

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Convergence by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Key Challenge Areas for Convergence and Health Pdf

Convergence of the life sciences with fields including physical, chemical, mathematical, computational, engineering, and social sciences is a key strategy to tackle complex challenges and achieve new and innovative solutions. However, institutions face a lack of guidance on how to establish effective programs, what challenges they are likely to encounter, and what strategies other organizations have used to address the issues that arise. This advice is needed to harness the excitement generated by the concept of convergence and channel it into the policies, structures, and networks that will enable it to realize its goals. Convergence investigates examples of organizations that have established mechanisms to support convergent research. This report discusses details of current programs, how organizations have chosen to measure success, and what has worked and not worked in varied settings. The report summarizes the lessons learned and provides organizations with strategies to tackle practical needs and implementation challenges in areas such as infrastructure, student education and training, faculty advancement, and inter-institutional partnerships.

Mathematical Challenges from Theoretical/Computational Chemistry

National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Mathematical Challenges from Computational Chemistry
Mathematical Challenges from Theoretical Computational Chemistry Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Mathematical Challenges from Computational Chemistry
Publisher : National Academies Press
Page : 143 pages
File Size : 43,6 Mb
Release : 1995-03-29
Category : Mathematics
ISBN : 9780309176620

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Mathematical Challenges from Theoretical/Computational Chemistry by National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Mathematical Challenges from Computational Chemistry Pdf

Computational methods are rapidly becoming major tools of theoretical, pharmaceutical, materials, and biological chemists. Accordingly, the mathematical models and numerical analysis that underlie these methods have an increasingly important and direct role to play in the progress of many areas of chemistry. This book explores the research interface between computational chemistry and the mathematical sciences. In language that is aimed at non-specialists, it documents some prominent examples of past successful cross-fertilizations between the fields and explores the mathematical research opportunities in a broad cross-section of chemical research frontiers. It also discusses cultural differences between the two fields and makes recommendations for overcoming those differences and generally promoting this interdisciplinary work.

Report of a Workshop on the Pedagogical Aspects of Computational Thinking

National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee for the Workshops on Computational Thinking
Report of a Workshop on the Pedagogical Aspects of Computational Thinking Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee for the Workshops on Computational Thinking
Publisher : National Academies Press
Page : 176 pages
File Size : 46,6 Mb
Release : 2011-09-05
Category : Education
ISBN : 9780309214742

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Report of a Workshop on the Pedagogical Aspects of Computational Thinking by National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee for the Workshops on Computational Thinking Pdf

In 2008, the Computer and Information Science and Engineering Directorate of the National Science Foundation asked the National Research Council (NRC) to conduct two workshops to explore the nature of computational thinking and its cognitive and educational implications. The first workshop focused on the scope and nature of computational thinking and on articulating what "computational thinking for everyone" might mean. A report of that workshop was released in January 2010. Drawing in part on the proceedings of that workshop, Report of a Workshop of Pedagogical Aspects of Computational Thinking, summarizes the second workshop, which was held February 4-5, 2010, in Washington, D.C., and focuses on pedagogical considerations for computational thinking. This workshop was structured to gather pedagogical inputs and insights from educators who have addressed computational thinking in their work with K-12 teachers and students. It illuminates different approaches to computational thinking and explores lessons learned and best practices. Individuals with a broad range of perspectives contributed to this report. Since the workshop was not intended to result in a consensus regarding the scope and nature of computational thinking, Report of a Workshop of Pedagogical Aspects of Computational Thinking does not contain findings or recommendations.

Fueling Innovation and Discovery

National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on the Mathematical Sciences in 2025
Fueling Innovation and Discovery Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on the Mathematical Sciences in 2025
Publisher : National Academies Press
Page : 64 pages
File Size : 42,7 Mb
Release : 2012-08-02
Category : Mathematics
ISBN : 9780309254731

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Fueling Innovation and Discovery by National Research Council,Division on Engineering and Physical Sciences,Board on Mathematical Sciences and Their Applications,Committee on the Mathematical Sciences in 2025 Pdf

The mathematical sciences are part of everyday life. Modern communication, transportation, science, engineering, technology, medicine, manufacturing, security, and finance all depend on the mathematical sciences. Fueling Innovation and Discovery describes recent advances in the mathematical sciences and advances enabled by mathematical sciences research. It is geared toward general readers who would like to know more about ongoing advances in the mathematical sciences and how these advances are changing our understanding of the world, creating new technologies, and transforming industries. Although the mathematical sciences are pervasive, they are often invoked without an explicit awareness of their presence. Prepared as part of the study on the Mathematical Sciences in 2025, a broad assessment of the current state of the mathematical sciences in the United States, Fueling Innovation and Discovery presents mathematical sciences advances in an engaging way. The report describes the contributions that mathematical sciences research has made to advance our understanding of the universe and the human genome. It also explores how the mathematical sciences are contributing to healthcare and national security, and the importance of mathematical knowledge and training to a range of industries, such as information technology and entertainment. Fueling Innovation and Discovery will be of use to policy makers, researchers, business leaders, students, and others interested in learning more about the deep connections between the mathematical sciences and every other aspect of the modern world. To function well in a technologically advanced society, every educated person should be familiar with multiple aspects of the mathematical sciences.

Globalization, Biosecurity, and the Future of the Life Sciences

National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
Globalization Biosecurity and the Future of the Life Sciences Book PDF

Author : National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
Publisher : National Academies Press
Page : 316 pages
File Size : 40,7 Mb
Release : 2006-06-07
Category : Science
ISBN : 9780309164757

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Globalization, Biosecurity, and the Future of the Life Sciences by National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats Pdf

Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.

Research Briefings 1986

National Academy of Sciences, National Academy of Engineering, Institute of Medicine,Committee on Science, Engineering, and Public Policy
Research Briefings 1986 Book PDF

Author : National Academy of Sciences, National Academy of Engineering, Institute of Medicine,Committee on Science, Engineering, and Public Policy
Publisher : National Academies Press
Page : 73 pages
File Size : 51,8 Mb
Release : 1986-02-01
Category : Political Science
ISBN : 9780309036894

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Research Briefings 1986 by National Academy of Sciences, National Academy of Engineering, Institute of Medicine,Committee on Science, Engineering, and Public Policy Pdf

Prepared for the Office of Science and Technology Policy and the National Science Foundation, these briefings examine areas important to the progress of U.S. science and technology: the science of interfaces and thin films, decision making and problem solving, protein structure and biological function, and the prevention and treatment of viral diseases.

Bio-Inspired Innovation and National Security

National Defense University
Bio Inspired Innovation and National Security Book PDF

Author : National Defense University
Publisher : NDU Press
Page : 356 pages
File Size : 54,8 Mb
Release : 2010-10
Category : History
ISBN : 9781780390406

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Bio-Inspired Innovation and National Security by National Defense University Pdf

Despite the vital importance of the emerging area of biotechnology and its role in defense planning and policymaking, no definitive book has been written on the topic for the defense policymaker, the military student, and the private-sector bioscientist interested in the "emerging opportunities market" of national security. This edited volume is intended to help close this gap and provide the necessary backdrop for thinking strategically about biology in defense planning and policymaking. This volume is about applications of the biological sciences, here called "biologically inspired innovations," to the military. Rather than treating biology as a series of threats to be dealt with, such innovations generally approach the biological sciences as a set of opportunities for the military to gain strategic advantage over adversaries. These opportunities range from looking at everything from genes to brains, from enhancing human performance to creating renewable energy, from sensing the environment around us to harnessing its power.