Biologics In Inflammatory Bowel Disease An Issue Of Gastroenterology Clinics Of North America
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Author : Edward V. Loftus, Jr Publisher : Elsevier Health Sciences Page : 257 pages File Size : 55,6 Mb Release : 2014-08-21 Category : Medical ISBN : 9780323323260
Biologics in Inflammatory Bowel Disease, An issue of Gastroenterology Clinics of North America, by Edward V. Loftus, Jr Pdf
By the time this issue of Gastroenterology Clinics of North America is released, it will have been 16 years since infliximab was approved by the US Food and Drug Administration for the treatment of moderate to severe Crohn disease. Not only have we come a long way in understanding the efficacy and safety of infliximab, we are beginning to understand how and when to use the drug. Furthermore, as of this writing, we have five other biologic agents approved for either Crohn disease or ulcerative colitis, and there are many more molecules currently in drug development for these indications. In this issue,the Editors have assembled a collection of experts to provide the most cutting-edge information on the status of biologic therapy for inflammatory bowel disease.
Author : Edward V. Loftus, Jr Publisher : Elsevier Health Sciences Page : 128 pages File Size : 52,7 Mb Release : 2017-09-15 Category : Medical ISBN : 9780323545556
Crohn's Disease, An Issue of Gastroenterology Clinics of North America by Edward V. Loftus, Jr Pdf
Dr. Loftus is a widely recognized expert in the diagnosis and treatment of Crohn's disease. He has created an issue devoted the current state-of-the-art on Crohn's disease; authors have written comprehensive reviews on the latest research to inform clinical diagnosis and treatment. Articles are devoted to the following topics: Genetics; Epidemiology, natural history, and risk stratification of Crohn’s disease; The microbiome in Crohn’s disease: Role in pathogenesis and role of microbiome replacement therapies; Endoscopic and radiographic assessment of Crohn’s disease; Intestinal and non-intestinal cancer risk in Crohn’s disease; Sexuality, fertility, and pregnancy in Crohn’s disease; Interdisciplinary management of perianal Crohn’s disease; Targeting specific immunologic pathways in human inflammatory bowel disease; Evolution of treatment paradigms in Crohn’s disease; Preventing and managing postoperative recurrence of Crohn’s disease; Where and how to use anti-TNF agents and anti-integrins in Crohn’s disease; Ustekinumab and anti-interleukin-23 agents in Crohn’s disease; Update on therapeutic drug monitoring in Crohn’s disease; and Janus kinase antagonists and other novel small molecules for the treatment of Crohn’s disease. Readers will come away from this issue armed with the information they need to improve management of this disease as well as patient outcomes.
Ulcerative Colitis, An Issue of Gastroenterology Clinics of North America, E-Book by Scott Lee Pdf
Together with Consulting Editor, Dr. Alan Buchman, Dr. Scott Lee has put together a state-of-the-art issue of Gastroenterology Clinics devoted to Ulcerative Colitis (UC). He has selected expert authors to contribute clinical reviews that provide the latest clinical findings and recommendations. Articles are devoted to the following topics: Epidemiology and pathogenesis of UC; Making initial diagnosis of UC and ruling out other diseases that mimic UC; Assessing severity of disease; Initial medical treatment of UC; Treatment of UC with steroids; Biologic therapy in UC; Non-biologic immune suppression in UC; Microbiome and fecal transplant in UC; Health maintenance in UC, including bone density scan, vaccination recommendations, cancer screening; Women's issues and UC; Risk of colon cancer and recommended surveillance strategies in UC patients; Surgical management of UC, indications and outcomes from colectomy; and Management of J-pouches. Readers will come away with the latest clinical recommendations they need to improve outcomes in patients with UC.
Pediatric Inflammatory Bowel Disease, An Issue of Gastroenterology Clinics of North America, E-Book by Marla Dubinsky Pdf
In this issue of Gastroenterology Clinics, guest editor Dr. Marla Dubinsky brings her considerable expertise to the topic of Pediatric Inflammatory Bowel Disease. Pediatric patients with IBD become adult patients with IBD, making it imperative that children receive early, effective intervention to optimize their growth and development, minimize disease complications, and support patients on their journey from childhood to adulthood. In this issue, top experts provide up-to-date information that helps provide an evidence-based approach for each patient. Contains 11 practice-oriented topics including optimizing the transition and transfer of care in pediatric IBD; building a self-management toolkit for pediatric IBD patients; choosing the right therapy at the right time for pediatric IBD: does sequence matter?; the state of clinical trials in pediatric IBD; the role of diet in pediatric IBD; and more. Provides in-depth clinical reviews on pediatric inflammatory bowel disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Medical and Surgical Management of Crohn’s Disease, An Issue of Gastroenterology Clinics of North America, E-Book by Sunanda V. Kane Pdf
In this issue of Gastroenterology Clinics, guest editor Dr. Sunanda V. Kane brings her considerable expertise to the topic of Medical and Surgical Management of Crohn’s Disease. Approximately 3 million people worldwide suffer with Crohn’s Disease, and this issue provides a thorough review of current treatment and management strategies in various patient populations. Topics include fecal microbiota transplant, microbiome-targeting diet, anti-TNF therapy in pediatric IBD patients, and many more. Contains 13 practice-oriented topics including mimics of Crohn’s; newer therapies for Crohn’s disease; diet and nutrition in Crohn’s disease; pediatric management of Crohn’s disease; and more. Provides in-depth clinical reviews of medical and surgical management of Crohn’s disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Challenges in Inflammatory Bowel Disease by Miguel Regueiro,Arthur M. Barrie (III.) Pdf
The Guest Editors for this issue have assembled top experts to discuss only those most challenging aspects of diagnosis and treatment of inflammatory bowel disease. Emphasis is on comparing treatment paradigms, current and future biologics agents, safety profile of therapeutics, and novel diagnostic and prognostic tools for IBD. Articles are also devoted to pregnancy and IBD, IBD in children, and post-operative management of IBD.
Inflammatory Bowel Disease, An Issue of Surgical Clinics, by Kerry L. Hammond Pdf
Inflammatory Bowel Disease is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Inflammatory Bowel Disease: Historical Perspective, Epidemiology and Risk Factors; Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy; Diagnostic Modalities for Inflammatory Bowel Disease: Radiologic Imaging; Medical Therapy for Inflammatory Bowel Disease; Crohn's Disease of the Foregut and Small Intestine; Crohn's Disease of the Colon, Rectum and Anus; Indications and Options for Surgery in Ulcerative Colitis; Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease; Extraintestinal Manifestations of Inflammatory Bowel Disease; Colorectal Neoplasia and Inflammatory Bowel Disease; Nutritional Support of the Inflammatory Bowel Disease Patient; Psychosocial Support of the Inflammatory Bowel Disease Patient; Genetics and Pathogenesis of Inflammatory Bowel Disease; and more!
Evaluation of Inflammatory Bowel Disease, An Issue of Gastroenterology Clinics- E-Book by Samir Shah,Edward Feller,Adam Harris Pdf
The Guest Editors have focused on methods of diagnosing and evaluating IBD to help guide optimal treatment to maximize clinical outcomes and minimize risks. Authors have provided state-of-the-art updates with practical information/guidelines/algorithms and cutting-edge data for incorporation into practice. The first set of articles deals with endoscopy: its role in diagnosis and monitoring IBD; the growing importance of chromoendoscopy in IBD surveillance exams; assessment of post-operative recurrence; and finally the emerging role of capsule endoscopy. The second section focuses on specific scenarios that IBD physicians encounter frequently: health maintenance in IBD focusing on proper vaccinations; the growing problem of Clostridium difficile in IBD; assessment of pouch problems; optimal evaluation of perianal disease; the state of the art in using thiopurines including use of allopurinol to optimize metabolites and optimizing the use of infliximab by measuring levels and antibodies to infliximab; factors to consider in choosing monotherapy versus combination therapy and communication of risk/benefit to patients; and finally disability assessment in IBD. The third and final section highlights noninvasive methods to evaluate IBD: clinical predictors of aggressive or disabling disease; the evolving role of specific antibodies in diagnosing, subtyping and most recently prognosticating in IBD; stool markers (calproctectin and lactoferrin) for evaluating and monitoring IBD; the growing role of imaging modalities with emphasis on MR enterography and CT enterography; and finally, the genetics of IBD and the potential role of genetic testing in the diagnosis/prognosis and tailoring of therapy.
Scott Plevy Associate Professor of Medicine Division of Gastroenterology
Author : Scott Plevy Associate Professor of Medicine Division of Gastroenterology Publisher : Oxford University Press, USA Page : 64 pages File Size : 55,6 Mb Release : 2010 Category : Medical ISBN : 9780199749188
Biologics in Inflammatory Bowel Disease by Scott Plevy Associate Professor of Medicine Division of Gastroenterology Pdf
SERIES OVERVIEW: The Oxford American Pocket Notes are a series of ultra-concise, small-format books for healthcare professionals on topics related to the diagnosis, treatment and management of various medical conditions. Each title typically features an outline of key points, guidelines and tools such as patient assessments and treatment algorithms, for a specific area of medical diagnosis and/or management. Highly practical in format, content and style, the Pocket Notes serve as a quick, easily accessible point-of-care reference for busy practitioners. In effect, they are miniature versions of the Oxford American Medical Library and Oxford American Handbooks in Medicine, capturing the key essentials needed for appropriate assessment and treatment. Inflammatory bowel disease (IBD) is a gastrointestinal condition which causes inflammation of the lining of the digestive tract. This disease affects an estimated one million Americans, usually in the forms of ulcerative colitis (UC) and Crohn's disease (CD). These two diseases have similar symptoms and are often confused for one another. Crohn's disease can occur anywhere in the digestive tract, often spreading deep into the layers of affected tissues, but ulcerative colitis usually affects only the innermost lining (mucosa) of the large intestine and rectum. IBD patients suffer from severe diarrhea and abdominal pain, and may experience other complications, such as arthritis and kidney stones, that affect the body beyond the intestinal tract. The Oxford American Pocket Notes: Biologics in Inflammatory Bowel Disease is a practical guide to the safe administration of biological agents to treat inflammatory gastrointestinal illnesses. This ultra-concise and practical volume focuses on tumor necrosis factor (TNF) blocking therapy (TNF blocker), an important new class of biologic therapy indicated for the treatment of several rheumatic and other auto-immune disorders, including Crohn's disease and ulcerative colitis. This uniquely compact and affordable book features evidence-based discussion and guidelines on the mechanism of action, dosing, administration and safety considerations for the biologic agents approved to treat CD and UC, thus providing practicing physicians with easily accessible tools and insights on the use of these drugs in a daily practice setting. Culled from the pages of Handbook of Biological Therapy, this portable guide is a valuable resource for gastroenterologists, primary care physicians and other healthcare providers involved in the management of these chronic but treatable diseases.
Treatment of Inflammatory Bowel Disease with Biologics by Adam S. Cheifetz,Joseph D. Feuerstein Pdf
This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn’s disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
Inflammatory Bowel Disease, An Issue of Surgical Clinics by Sean J. Langenfeld Pdf
This issue of Surgical Clinics of North America focuses on Inflammatory Bowel Disease and is edited by Dr. Sean Langenfeld. Articles will include: IBD presentation and diagnosis; Endoscopy in IBD; Preoperative considerations in IBD; Postoperative Considerations in IBD; IBD and cancer/dysplasia; Elective abdominal surgery for IBD; Abdominal emergencies in IBD; Anorectal Crohn’s disease; Other surgeries in IBD patients; Pediatric inflammatory bowel disease; Pouch complications; Genetic and environmental considerations for IBD; IBD and short bowel syndrome; Medical Management of IBD; and more!
Laboratory Monitoring of Gastrointestinal and Hepatobiliary Disease, An Issue of Gastroenterology Clinics of North America by Stanley J Naides Pdf
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Stanley J. Naides has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to Laboratory Monitoring of Gastrointestinal and Hepatobiliary Disease. Clinical review articles from expert authors are specifically devoted to the following: Inborn Errors of Metabolism and the GI track; Primary Immunodeficiency and the gut; Liver fibrosis determination; IBD; Autoimmune liver disease diagnosis and classification; Laboratory Diagnosis of Viral hepatitis; IgG4-RD with Emphasis on its GI Manifestation; Bowel Microbiome in Health and Disease; AAV System; and Celiac Disease. Readers will come away with the latest information they need to diagnose and monitor patients with gastrointestinal and hepatobiliary disease.
Pediatric Inflammatory Bowel Disease, an Issue of Gastroenterology Clinics of North America: Volume 52-3 by Marla Dubinsky Pdf
In this issue of Gastroenterology Clinics, guest editor Dr. Marla Dubinsky brings her considerable expertise to the topic of Pediatric Inflammatory Bowel Disease. Pediatric patients with IBD become adult patients with IBD, making it imperative that children receive early, effective intervention to optimize their growth and development, minimize disease complications, and support patients on their journey from childhood to adulthood. In this issue, top experts provide up-to-date information that helps provide an evidence-based approach for each patient. Contains 11 practice-oriented topics including optimizing the transition and transfer of care in pediatric IBD; building a self-management toolkit for pediatric IBD patients; choosing the right therapy at the right time for pediatric IBD: does sequence matter?; the state of clinical trials in pediatric IBD; the role of diet in pediatric IBD; and more. Provides in-depth clinical reviews on pediatric inflammatory bowel disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Biological Therapy for Inflammatory Bowel Disease by Raquel Franco Leal,Tristan Torriani Pdf
The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-alpha) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment. The aim of this book is to provide an overview of such drugs and the latest developments in IBD immunopathology. Our contributors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.
