Biomimetic Lipid Membranes Fundamentals Applications And Commercialization

Author : Fatma N. Kök,Ahu Arslan Yildiz,Fatih Inci
Publisher : Springer
Page : 306 pages
File Size : 53,6 Mb
Release : 2019-04-16
Category : Technology & Engineering
ISBN : 9783030115968

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Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization by Fatma N. Kök,Ahu Arslan Yildiz,Fatih Inci Pdf

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development. Provides fundamental knowledge on biomimetic lipid membranes; Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques; Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques; Describes the integration of biomimetic membranes with current top-notch tools and platforms; Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

Author : Donald Martin
Publisher : Springer Science & Business Media
Page : 183 pages
File Size : 43,6 Mb
Release : 2007-12-26
Category : Science
ISBN : 9780387377407

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Nanobiotechnology of Biomimetic Membranes by Donald Martin Pdf

This book describes the current state of research and development in biomimetic membranes for nanobiotechnology applications. It takes an international perspective on the issue of developing biotechnology applications from an understanding of the biomimetic membrane at the nanoscale. The success of these applications relies on a good understanding of the interaction and incorporation of macromolecules in membranes and the fundamental properties of the membrane itself.

Author : Claus Hélix-Nielsen
Publisher : Springer Science & Business Media
Page : 303 pages
File Size : 48,7 Mb
Release : 2012-01-02
Category : Science
ISBN : 9789400721845

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Biomimetic Membranes for Sensor and Separation Applications by Claus Hélix-Nielsen Pdf

This book addresses the possibilities and challenges in mimicking biological membranes and creating membrane-based sensor and separation devices. Recent advances in developing biomimetic membranes for technological applications will be presented with focus on the use of integral membrane protein mediated transport for sensing and separation. It describes the fundamentals of biosensing as well as separation and shows how the two processes are working in a cooperative manner in biological systems. Biomimetics is a truly cross-disciplinary approach and this is exemplified using the process of forward osmosis will be presented as an illustration of how advances in membrane technology may be directly stimulated by an increased understanding of biological membrane transport. In the development of a biomimetic sensor/separation technology, both channels (ion and water channels) and carriers (transporters) are important. An ideal sensor/separation device requires the supporting biomimetic matrix to be virtually impermeable to anything but the solute in question. In practice, however, a biomimetic support matrix will generally have finite permeabilities to water, electrolytes, and non-electrolytes. These non-protein mediated membrane transport contributions will be presented and the implications for biomimetic device construction will be discussed. New developments in our understanding of the reciprocal coupling between the material properties of the biomimetic matrix and the embedded proteins will be presented and strategies for inducing biomimetic matrix stability will be discussed. Once reconstituted in its final host biomimetic matrix the protein stability also needs to be maintained and controlled. Beta-barrel proteins exemplified by the E. Coli outer membrane channels or small peptides are inherently more stable than alpha-helical bundle proteins which may require additional stabilizing modifications. The challenges associated with insertion and stabilization of alpha-helical bundle proteins including many carriers and ligand and voltage gated ion (and water) channels will be discussed and exemplified using the aquaporin protein. Many biomimetic membrane applications require that the final device can be used in the macroscopic realm. Thus a biomimetic separation device must have the ability to process hundred of liters of permeate in hours – effectively demanding square-meter size membranes. Scalability is a general issue for all nano-inspired technology developments and will be addressed here in the context biomimetic membrane array fabrication. Finally a robust working biomimetic device based on membrane transport must be encapsulated and protected yet allowing massive transport though the encapsulation material. This challenge will be discussed using microfluidic design strategies as examples of how to use microfluidic systems to create and encapsulate biomimetic membranes. The book provides an overview of what is known in the field, where additional research is needed, and where the field is heading.

Author : Cyrus R. Safinya,Joachim Radler
Publisher : CRC Press
Page : 371 pages
File Size : 51,5 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9781466555730

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Handbook of Lipid Membranes by Cyrus R. Safinya,Joachim Radler Pdf

This handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology. Key Features: Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution Covers advanced X-ray and force measurement techniques Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.

Author : Raz Jelinek
Publisher : Walter de Gruyter GmbH & Co KG
Page : 314 pages
File Size : 47,9 Mb
Release : 2018-05-07
Category : Technology & Engineering
ISBN : 9783110453690

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Membranes by Raz Jelinek Pdf

Describes the properties of cellular membranes and their relationship with fundamental biological processes. This book provides insight on the chemistry, structures, model systems, and techniques employed for studying membrane properties and processes. A major focus is on the prominence of membranes in diverse physiological processes and disease, as well as applications of membranes and biomimetic membrane systems in varied disciplines. The book aims to illuminate the significance and beauty of membrane science, and serve both as an entry point for scholars wishing to embark on membrane research, as well as scientists already working in the field.

Author : Georg Pabst,Norbert Kucerka,Mu-Ping Nieh,John Katsaras
Publisher : CRC Press
Page : 470 pages
File Size : 55,7 Mb
Release : 2014-03-04
Category : Medical
ISBN : 9781466507111

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Liposomes, Lipid Bilayers and Model Membranes by Georg Pabst,Norbert Kucerka,Mu-Ping Nieh,John Katsaras Pdf

As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evo

Author : Anonim
Publisher : Academic Press
Page : 226 pages
File Size : 49,8 Mb
Release : 2020-04-07
Category : Science
ISBN : 9780128209783

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Advances in Biomembranes and Lipid Self-Assembly by Anonim Pdf

Advances in Biomembranes and Lipid Self-assembly, Volume 31, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers. Surveys recent theoretical and experimental results on lipid micro- and nanostructures Presents potential use applications, such as clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products Includes both original research and comprehensive reviews written by world-leading experts and young researchers Provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale

Author : Leonid Bulavin,Nikolai Lebovka
Publisher : Springer Nature
Page : 456 pages
File Size : 49,9 Mb
Release : 2021-09-27
Category : Science
ISBN : 9783030809249

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Soft Matter Systems for Biomedical Applications by Leonid Bulavin,Nikolai Lebovka Pdf

This book addresses new challenges in soft matter and colloids. It presents timely reports on colloidal self-assembly, soft matters from liquid crystals, nanoparticles in liquid crystals, hydrocolloids, hybrid nanosystems, nanosuspensions, and dispersion of nanoparticles in different media, soft matter processing and modern experiments related with soft matters.

Author : Anonim
Publisher : Academic Press
Page : 328 pages
File Size : 52,7 Mb
Release : 2019-11-27
Category : Science
ISBN : 9780128174845

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Multiresponsive Behavior of Biomembranes and Giant Vesicles by Anonim Pdf

Biomembranes consist of molecular bilayers with many lipid and protein components. The fluidity of these bilayers allows them to respond to different environmental cues by changing their local molecular composition as well as their shape and topology. On the nanometer scale, this multi-responsive behavior can be studied by molecular dynamics simulations, which provide both snapshots and movies of the bilayer conformations. The general conceptual framework for these simulations is provided by the theory of curvature elasticity. The latter theory also explains the behavior of giant vesicles as observed by optical microscopy on the micrometer scale. The present volume describes new insights as obtained from recent developments in analytical theory, computer simulations, and experimental approaches. The seven chapters of the volume are arranged in a bottom-up manner from smaller to larger scales. These chapters address the refined molecular dynamics and multiscale modeling of biomembranes, their morphological complexity and adhesion, the engulfment and endocytosis of nanoparticles, the fusion of giant unilamellar vesicles, as well as recent advances in microfluidic technology applied to model membranes. Bridging the gap between lipid molecules and giant unilamellar vesicles (GUVs) Integrated view obtained from analytical theory, computer simulations, and experimental observations Multiresponsive behavior and morphological complexity of biomembranes

Author : Swati Kapoor,Gurkirat Kaur,B. N. Dar,Savita Sharma
Publisher : CRC Press
Page : 260 pages
File Size : 54,7 Mb
Release : 2023-12-22
Category : Technology & Engineering
ISBN : 9781000970081

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Emerging Techniques for Food Processing and Preservation by Swati Kapoor,Gurkirat Kaur,B. N. Dar,Savita Sharma Pdf

The demand for safe and healthy foods by consumers has increased the interest in developing new food processing techniques over the past decades. Emerging technologies and techniques are not just working to increase the shelf life of food but are also functioning to maintain the same quality of the food that makes it desirable in the first place. Emerging Techniques for Food Processing and Preservation is an essential guide for professionals and researchers in the food industry who seek to stay updated on the latest advancements in food processing and preservation techniques. This comprehensive book explores cutting-edge technologies that can enhance the quality and safety of food products while also improving their shelf life. With contributions from leading experts in the field, this book covers a wide range of topics, including Electrodialysis, Refractance Window Technology, Cold Plasma, Bio Speckle Laser Technique, Nanofluids, and many others. Each chapter includes detailed explanations of the principles behind these emerging techniques, as well as case studies that demonstrate their practical applications. In this book, readers will gain insights into the principles behind these emerging techniques, their advantages and limitations, and the practical applications in various food products. Whether you are a food scientist, engineer, or a food industry professional, this book will help you stay at the forefront of the rapidly evolving landscape of food processing and preservation.

Author : Yasser Shahzad,Syed A.A. Rizvi,Abid Mehmood Yousaf,Talib Hussain
Publisher : CRC Press
Page : 360 pages
File Size : 46,5 Mb
Release : 2022-01-18
Category : Medical
ISBN : 9781000529494

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Drug Delivery Using Nanomaterials by Yasser Shahzad,Syed A.A. Rizvi,Abid Mehmood Yousaf,Talib Hussain Pdf

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Author : Dimitrios A. Lamprou
Publisher : Springer Nature
Page : 494 pages
File Size : 45,8 Mb
Release : 2024-06-28
Category : Electronic
ISBN : 9783031607172

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Microfluidics in Pharmaceutical Sciences by Dimitrios A. Lamprou Pdf

Author : Rajeev Bhat
Publisher : Academic Press
Page : 788 pages
File Size : 45,9 Mb
Release : 2021-12-04
Category : Technology & Engineering
ISBN : 9780323910026

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Future Foods by Rajeev Bhat Pdf

Future Foods: Global Trends, Opportunities, and Sustainability Challenges highlights trends and sustainability challenges along the entire agri-food supply chain. Using an interdisciplinary approach, this book addresses innovations, technological developments, state-of-the-art based research, value chain analysis, and a summary of future sustainability challenges. The book is written for food scientists, researchers, engineers, producers, and policy makers and will be a welcomed reference. Provides practical solutions for overcoming recurring sustainability challenges along the entire agri-food supply chain Highlights potential industrial opportunities and supports circular economy concepts Proposes novel concepts to address various sustainability challenges that can affect and have an impact on the future generations

Author : J. Katsaras,T. Gutberlet
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 46,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783662044964

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Lipid Bilayers by J. Katsaras,T. Gutberlet Pdf

Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.

Author : Sanjay K. Nayak,Kingshuk Dutta,Jaydevsinh M. Gohil
Publisher : Elsevier
Page : 677 pages
File Size : 51,7 Mb
Release : 2022-02-23
Category : Science
ISBN : 9780323885171

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Advancement in Polymer-Based Membranes for Water Remediation by Sanjay K. Nayak,Kingshuk Dutta,Jaydevsinh M. Gohil Pdf

Advancements in Polymer-Based Membranes for Water Remediation describes the advanced membrane science and engineering behind the separation processes within the domain of polymer-based membrane systems in water remediation. Emphasis has been put on several aspects, ranging from fundamental concepts to the commercialization of pressure and potential driven membranes, updated with the latest technological progresses, and relevant polymer materials and application potential towards water treatment systems. Also included in this book are advances in polymers for membrane application in reverse osmosis, nanofiltration, ultrafiltration, microfiltration, forward osmosis, and polymeric ion-exchange membranes for electrodialysis and capacitive deionization. With its critical analyzes and opinions from experts around the world, this book will garner considerable interest among actual users, i.e., scientists, engineers, industrialists, entrepreneurs and students. Evaluates water remediation using pressure driven and potential driven membrane processes Reviews emerging polymer systems for membranes preparation Offers a comprehensive analysis in the development of polymer-based membranes and their applications in water remediation Analyzes membrane performance parameters to evaluate separation efficiency for various water pollutants Covers concept-to-commercialization aspects of polymer-based membranes in terms of water purification, pollutant removal, stability and scalability