Biotechnology Of Antibiotics And Other Bioactive Microbial Metabolites

Author : G. Lancini,R. Lorenzetti
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 54,6 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781475795226

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Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites by G. Lancini,R. Lorenzetti Pdf

In response to the field's need for an introductory text, the authors have distilled the vast and scattered literature relating to the biotechnology of microbial secondary metabolites. General biology, biosynthesis, the search for novel metabolites, and techniques for strain improvement are all discussed to provide undergraduate and graduate students with a concise, readable overview of the field.

Author : G. Lancini,R. Lorenzetti
Publisher : Unknown
Page : 248 pages
File Size : 50,5 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1475795238

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Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites by G. Lancini,R. Lorenzetti Pdf

Author : Satoshi Omura
Publisher : Springer Science & Business Media
Page : 373 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461244127

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The Search for Bioactive Compounds from Microorganisms by Satoshi Omura Pdf

Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.

Author : M. E. Bushell,Udo Gräfe
Publisher : Elsevier Publishing Company
Page : 438 pages
File Size : 41,6 Mb
Release : 1989
Category : Antibiotics
ISBN : UCSD:31822005117999

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Bioactive Metabolites from Microorganisms by M. E. Bushell,Udo Gräfe Pdf

This volume summarizes major approaches and recent developments in the research on new bioactive metabolites of microbial origin including target-directed screening strategies, evaluation of new drugs, biosynthesis, genetic manipulation, and semisynthesis. Particular attentonis given to new microbial sources of drugs, new approaches towards directed screening, advances and future perspectives in antimicrobial, antineoplastic and phytoeffectory agents, and enzyme inhibitors as pharmacological agents. The contributions represent comprehensive surveys written by recognized scientists active in their fields of research. Together, they give an interdisciplinary view which focusses on exploitation of available microbial sources for drug development, problems of evaluation, mode of action, biosynthesis and application. The book will be of interest to scientists working in microbiology, pharmacology, pharmaceutical chemistry and pharmaceutical biotechnology.

Author : Vaibhav Mishra,Jitendra Mishra,Naveen Kumar Arora
Publisher : Elsevier
Page : 366 pages
File Size : 44,8 Mb
Release : 2024-06
Category : Science
ISBN : 9780443185687

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Bioactive Microbial Metabolites by Vaibhav Mishra,Jitendra Mishra,Naveen Kumar Arora Pdf

Bioactive microbial metabolites play an important role in expanding the market of antibiotics, food, and agriculture but also offer eco-friendly, safer, and profitable solutions to respective industries. Bioactive microbial metabolites Scope and Challenges searches out specific features and discusses future research of microbial metabolites with a wide perspective. Bioactive Microbial Metabolites: Scope and Challenges not only focuses on the identification, separation, and purification of bioactive metabolites, but also provides understanding of metabolic pathways for bioactive metabolites production that plays an important role in modern healthcare as frontline treatments for many diseases. Bioactive Microbial Metabolites: Scope and Challenges is a valuable reference for research students, academicians, and scientists in environmental microbiology and biotechnology and Industry personnel related to microbiology/ biotechnology. Focuses on the identification and structure elucidation of novel microbial metabolites Uncovers extended functions of microbial metabolites Provides understanding of metabolic pathways for bioactive metabolites production by using several illustrations, figures, and tables so that the reader can easily grasp key concepts

Author : L. J. Nisbet,D. J. Winstanley,Society for General Microbiology
Publisher : Academic Press
Page : 160 pages
File Size : 48,5 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015004484161

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Bioactive Microbial Products 2 by L. J. Nisbet,D. J. Winstanley,Society for General Microbiology Pdf

Author : Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani
Publisher : John Wiley & Sons
Page : 742 pages
File Size : 52,6 Mb
Release : 2015-04-20
Category : Technology & Engineering
ISBN : 9781118733493

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Biotechnology of Bioactive Compounds by Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani Pdf

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Author : Ajay Kumar,Joginder Singh,Jastin Samuel
Publisher : Academic Press
Page : 513 pages
File Size : 50,8 Mb
Release : 2021-06-22
Category : Science
ISBN : 9780323851640

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Volatiles and Metabolites of Microbes by Ajay Kumar,Joginder Singh,Jastin Samuel Pdf

Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains Responds to new developments in the detection of the complex compound structures of volatiles Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology

Author : William Strohl
Publisher : CRC Press
Page : 860 pages
File Size : 55,5 Mb
Release : 1997-07-03
Category : Medical
ISBN : 0824798678

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Biotechnology of Antibiotics, Second Edition, by William Strohl Pdf

This incomparable Second Edition of a highly regarded reference has been entirely rewritten and enlarged to reflect the explosion of information and technologies that have emerged since the publication of the previous edition. Strikes the perfect balance between proven traditional approaches and modern methods that promise to yield new products and processes! Specifically addressing microbially derived commercially important bioactive products that are currently or soon-to-be available, Biotechnology of Antibiotics, Second Edition analyzes the use of recombinant enzymes to produce biologically active molecules, including a cholesterol-lowering agent, an anti-HIV drug for the treatment of AIDS, and b-lactam antibiotics gives insight into the biochemistry, molecular biology, and production of antibiotics used as therapeutic agents focuses on state-of-the-art techniques for the development of new antibiotics using novel approaches and strategies highlights recent advances in the genetic manipulation of antibiotic biosynthesis genes to create structures from gene combinations for new biological activities describes in detail the development and current status of newly created antibiotics and pharmacologically active natural products and much more! Written by authorities from both industry and academia and containing nearly 4000 bibliographic citations, Biotechnology of Antibiotics, Second Edition is an outstanding resource for pharmaceutical scientists, medicinal chemists and biochemists, molecular biologists and industrial microbiologists, chemical engineers, fermentation bioengineers, bioprocess technologists, and upper-level undergraduate and graduate students in these disciplines.

Author : Vijai Singh
Publisher : Springer Nature
Page : 349 pages
File Size : 52,8 Mb
Release : 2020-04-13
Category : Science
ISBN : 9789811500817

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Advances in Synthetic Biology by Vijai Singh Pdf

This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Author : Vijai G. Gupta,Anita Pandey
Publisher : Elsevier
Page : 378 pages
File Size : 55,6 Mb
Release : 2019-06-15
Category : Medical
ISBN : 9780444635044

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New and Future Developments in Microbial Biotechnology and Bioengineering by Vijai G. Gupta,Anita Pandey Pdf

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. Compiles the latest developments in the area of microbial secondary metabolites Authored by the top international researchers in this area Includes information related to nearly all areas of a microbial secondary metabolites system

Author : Nina Gunde-Cimerman,Aharon Oren,Ana Plemenitaš
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 53,8 Mb
Release : 2005-09-30
Category : Science
ISBN : 1402036329

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Adaptation to Life at High Salt Concentrations in Archaea, Bacteria, and Eukarya by Nina Gunde-Cimerman,Aharon Oren,Ana Plemenitaš Pdf

Salt is an essential requirement of life. Already from ancient times (e. g. , see the books of the Bible) its importance in human life has been known. For example, salt symbolizes destruction (as in Sodom and Gomorra), but on the other hand it has been an ingredient of every sacrifice during the Holy Temple periods. Microbial life in concentrated salt solutions has fascinated scientists since its discovery. Recently there have been several international meetings and books devoted entirely to halophiles. This book includes the proceedings of the “Halophiles 2004” conference held in Ljubljana, Slovenia, in September 2004 (www. u- lj. si/~bfbhaloph/index. html). This meeting was attended by 120 participants from 25 countries. The editors have selected presentations given at the meeting for this volume, and have also invited a number of contributions from experts who had not been present in Ljubljana. This book complements “Halophilic Microorganisms”, edited by A. Ventosa and published by Springer-Verlag (2004), “Halophilic Microorganism and their Environments” by A. Oren (2002), published by Kluwer Academic Publishers as volume 5 of “Cellular Origins, Life in Extreme Habitats and Astrobiology” (COLE), and “Microbiology and Biogeochemistry of Hypersaline Environments” edited by A. Oren, and published by CRC Press, Boca Raton (1999). Salt-loving (halophilic) microorganisms grow in salt solutions above seawater salinity (~3. 5% salt) up to saturation ranges (i. e. , around 35% salt). High concentrations of salt occur in natural environments (e. g.

Author : Joachim Wink,Fatemeh Mohammadipanah,Javad Hamedi
Publisher : Springer
Page : 395 pages
File Size : 51,9 Mb
Release : 2017-10-19
Category : Science
ISBN : 9783319603391

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Biology and Biotechnology of Actinobacteria by Joachim Wink,Fatemeh Mohammadipanah,Javad Hamedi Pdf

This book provides in-depth insights into the biology, taxonomy, genetics, physiology and biotechnological applications of Actinobacteria. It especially focuses on the latter, reviewing the wide variety of actinobacterial bioactive molecules and their benefits for diverse industrial applications such as agriculture, aquaculture, biofuel production and food technology. Actinobacteria are one of the most promising sources of small bioactive molecules and it is estimated that only a small percentage of actinobacterial bioactive chemicals have been discovered to date. Identifying new diverse gene clusters of biotechnological relevance in the genome of Actinobacteria will be crucial to developing advanced applications for pharmaceutical, industrial and agricultural purposes. The book offers a unique resource for all graduate students, researchers and practitioners in the fields of microbiology, microbial biotechnology, and the genetic engineering of Actinobacteria.

Author : Bhim Pratap Singh,Mostafa E. Rateb,Susana Rodriguez-Couto,Maria de Lourdes Teixeira de Moraes Polizeli,Wen-Jun Li
Publisher : Frontiers Media SA
Page : 309 pages
File Size : 50,8 Mb
Release : 2019-08-02
Category : Electronic
ISBN : 9782889459018

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Microbial Secondary Metabolites: Recent Developments and Technological Challenges by Bhim Pratap Singh,Mostafa E. Rateb,Susana Rodriguez-Couto,Maria de Lourdes Teixeira de Moraes Polizeli,Wen-Jun Li Pdf

Research on microbes plays an essential role in the improvement of biotechnological and biomedical areas. It has turned into a subject of expanding significance as new organisms and their related biomolecules are being characterized for several applications in health and agriculture. Microbial biomolecules confer the ability of microbes to cope with a range of adverse conditions. However, these biomolecules have several advantages over the plant origin, which makes them a suitable target in drug discovery and development. The reasons could be that microbial sources can be genetically engineered to enhance the production of desired natural production by large-scale fermentation. The interaction between microbes and their biotic and abiotic environment is fundamental to numerous processes taking place in the biosphere. The natural environments and hosts of these microorganisms are extremely diverse being reflected by the fact that microbes are widespread and occur in nearly every biological community on Earth. This metabolic versatility makes microbes interesting objects for a range of economically important biotechnological applications. Most of the biotechniques are established but inefficient genetic engineering strategies are still a bottleneck for selected microbe producing industrial scale biomolecules. Therefore, untapped microbial biodiversity and related metablomics, give a noteworthy wellspring of biologicals for the advancement of meds, immunizations, enhanced plants and for other natural applications. The present eBook volume contains articles on microbial secondary metabolites, microbial biosynthetic potential including biosynthetic gene expression, and metagenomics obtained from microorganism isolated unique from habitats like marine sources, endophytes, thermal springs, deserts, etc.

Author : Andrew G. Mtewa,Chukwuebuka Egbuna,G. M. Narasimha Rao
Publisher : John Wiley & Sons
Page : 444 pages
File Size : 52,7 Mb
Release : 2020-12-22
Category : Science
ISBN : 9781119650232

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Poisonous Plants and Phytochemicals in Drug Discovery by Andrew G. Mtewa,Chukwuebuka Egbuna,G. M. Narasimha Rao Pdf

Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career