Bone Repair Biomaterials

Author : Kendell Pawelec,J. A. Planell
Publisher : Woodhead Publishing
Page : 506 pages
File Size : 53,9 Mb
Release : 2018-11-29
Category : Technology & Engineering
ISBN : 9780081024522

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Bone Repair Biomaterials by Kendell Pawelec,J. A. Planell Pdf

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Author : Joo L. Ong,Teja Guda
Publisher : CRC Press
Page : 263 pages
File Size : 48,8 Mb
Release : 2017-01-06
Category : Technology & Engineering
ISBN : 9781315363516

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Translating Biomaterials for Bone Graft by Joo L. Ong,Teja Guda Pdf

Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Author : K. Mallick
Publisher : Elsevier
Page : 352 pages
File Size : 44,7 Mb
Release : 2014-08-05
Category : Technology & Engineering
ISBN : 9780857099037

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Bone Substitute Biomaterials by K. Mallick Pdf

Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms. Provides a detailed and accurate overview of the bone substitute biomaterials, a fundamental part of the biomaterials and biomedical sector Provides readers with the principles of bone substitute biomaterials Reviews biomaterials for bone regeneration

Author : Jiacan Su,Yingying Jing,Xiao Chen
Publisher : John Wiley & Sons
Page : 213 pages
File Size : 49,5 Mb
Release : 2023-03-20
Category : Technology & Engineering
ISBN : 9783527350438

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Biomaterials Effect on the Bone Microenvironment by Jiacan Su,Yingying Jing,Xiao Chen Pdf

Biomaterials Effect on the Bone Microenvironment Practical resource on clinical bone regeneration from a variety of related interdisciplinary researchers Biomaterials Effect on the Bone Microenvironment focuses on the structure-activity relationship between bone biomaterials and microenvironment regulation, presenting a systematic exposition from all aspects of biomaterials regulated microenvironment in bone regeneration and covering design strategies, applications, and mechanisms of biomaterials that regulate bone microenvironment, along with the methods for manufacturing biomaterials and their clinical translation. The subject’s potential challenges and future development direction are discussed, and the design and initiative principle of tailored biomaterials with various features, including bioactive components and physicochemical property, are elucidated in depth. Numerous biomaterials, including natural and synthetic, are summarized and compared. Their advantages and features are also evaluated, particularly in bone microenvironmental regulation and bone generation. Moreover, the stimulation mechanism of the microenvironment to bone generation is discussed in detail, including mechanical-support effect, redox effect, pro-angiogenesis effect, inflammatory immune effect, and anti-aging effect. Biomaterials Effect on the Bone Microenvironment provides further coverage of sample topics such as: Role of bone microenvironment and its associated biomaterials in modulation bone diseases, reviewing the biomaterials used to regulate bone microenvironment Relationship between biological factors of various materials and physiological functions in bone microenvironment Application of the third generation of biomaterials, which would regenerate the bone to regulate bone microenvironment Emerging biological material manufacturing technology and mechanisms of novel biomaterial modulating microenvironment for bone regeneration Future outlook of bone tissue engineering along with the general process of bone remodeling and regeneration With comprehensive coverage of one of the most promising and valuable candidates for clinical bone regeneration, Biomaterials Effect on the Bone Microenvironment is an ideal resource for materials scientists, biotechnologists, biochemists, bioengineers, orthopedists, and clinical chemists who want to stay on the cutting edge of this rapidly evolving field.

Author : Yanjin Lu,Chunguang Yang,Yujing Liu,Guogang Ren,Changhui Song
Publisher : Frontiers Media SA
Page : 330 pages
File Size : 55,9 Mb
Release : 2024-01-15
Category : Technology & Engineering
ISBN : 9782832542729

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Advanced Biomaterials and 3D Printing Technologies in Bone Repair by Yanjin Lu,Chunguang Yang,Yujing Liu,Guogang Ren,Changhui Song Pdf

Author : Mario Barbosa,M Cristina L Martins
Publisher : Woodhead Publishing
Page : 390 pages
File Size : 49,8 Mb
Release : 2017-09-25
Category : Technology & Engineering
ISBN : 9780081008522

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Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair by Mario Barbosa,M Cristina L Martins Pdf

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Author : Michael J. Yaszemski
Publisher : CRC Press
Page : 465 pages
File Size : 41,7 Mb
Release : 2003-10-17
Category : Medical
ISBN : 9780824756864

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Biomaterials in Orthopedics by Michael J. Yaszemski Pdf

Written by respected experts in the field, Biomaterials in Orthopedics discusses bioabsorbable biomaterials for bone repair, nondegradable materials in orthopaedics and delivery systems. Topics in this text include biocompatibility and the biomaterial/tissue interface; self-reinforced bioabsorbable devices and guided regeneration; bone substitutes,

Author : Jiang Chang,Xingdong Zhang,Kerong Dai
Publisher : Academic Press
Page : 0 pages
File Size : 54,9 Mb
Release : 2020-03-03
Category : Technology & Engineering
ISBN : 0128135034

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Bioactive Materials for Bone Regeneration by Jiang Chang,Xingdong Zhang,Kerong Dai Pdf

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration.

Author : Jona J. Sela,Itai A. Bab
Publisher : Springer Science & Business Media
Page : 161 pages
File Size : 55,8 Mb
Release : 2012-03-13
Category : Technology & Engineering
ISBN : 9781461420583

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Principles of Bone Regeneration by Jona J. Sela,Itai A. Bab Pdf

Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.

Author : Herve Petite
Publisher : CRC Press
Page : 225 pages
File Size : 52,5 Mb
Release : 2005-08-15
Category : Science
ISBN : 9781498713535

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Engineered Bone by Herve Petite Pdf

This book addresses relevant issues that tissue-engineering researchers must consider when planning new strategies, especially in the bone and cartilage field. It describes transcription factors that are essential in bone development, and deals with bone healing.

Author : Jeffrey O. Hollinger,Thomas A. Einhorn,Bruce Doll,Charles Sfeir
Publisher : CRC Press
Page : 500 pages
File Size : 50,8 Mb
Release : 2004-10-14
Category : Medical
ISBN : 9781135501914

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Bone Tissue Engineering by Jeffrey O. Hollinger,Thomas A. Einhorn,Bruce Doll,Charles Sfeir Pdf

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Author : P. Dubruel,S. Van Vlierberghe
Publisher : Elsevier
Page : 502 pages
File Size : 51,8 Mb
Release : 2014-06-09
Category : Medical
ISBN : 9780857098108

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Biomaterials for Bone Regeneration by P. Dubruel,S. Van Vlierberghe Pdf

Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments. Provides comprehensive coverage of novel materials, techniques, and applications of biomaterials for bone regeneration Provides vital information on the various types of materials used in bone regeneration Discusses processing, modification, and evaluation techniques of biomaterials, and looks at cellular approaches and stimulation of biomaterials for bone regeneration

Author : Hala Zreiqat,Colin R. Dunstan,Vicki Rosen
Publisher : Springer
Page : 254 pages
File Size : 44,9 Mb
Release : 2014-12-05
Category : Technology & Engineering
ISBN : 9783319132662

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A Tissue Regeneration Approach to Bone and Cartilage Repair by Hala Zreiqat,Colin R. Dunstan,Vicki Rosen Pdf

Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Author : Mike Barbeck,Nahum Rosenberg,Zeljka Peric Kacarevic,Ole Jung,Patrick Rider
Publisher : Unknown
Page : 244 pages
File Size : 53,7 Mb
Release : 2021-10
Category : Electronic
ISBN : 1789858313

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Clinical Implementation of Bone Regeneration and Maintenance by Mike Barbeck,Nahum Rosenberg,Zeljka Peric Kacarevic,Ole Jung,Patrick Rider Pdf

Author : Susmita Bose,Amit Bandyopadhyay
Publisher : Academic Press
Page : 560 pages
File Size : 48,9 Mb
Release : 2016-11-03
Category : Technology & Engineering
ISBN : 9780128028032

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Materials and Devices for Bone Disorders by Susmita Bose,Amit Bandyopadhyay Pdf

Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts Includes input from a world-class team of research scientists, engineers, and clinicians Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders