Bone Sarcoma

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Sarcomas of Bone and Soft Tissues in Children and Adolescents

Author : Carola A. S. Arndt
Publisher : Springer Nature
Page : 181 pages
File Size : 48,9 Mb
Release : 2020
Category : Bone
ISBN : 9783030511609

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Sarcomas of Bone and Soft Tissues in Children and Adolescents by Carola A. S. Arndt Pdf

This book is a comprehensive and up-to-date compendium on all aspects of sarcomas of bone and soft tissues in childhood and adolescence. After introductory chapters on the history, epidemiology, and biology of pediatric sarcomas, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. The pathology and biology of this diverse group of tumors are extensively reviewed. Promising new treatment approaches are discussed, and strategies for the development of new agents are appraised. The major common pediatric sarcomas, including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma, are covered in detail. The authors are internationally recognized experts who offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of childhood and adolescent sarcomas and will prove invaluable to specialists, generalists, and trainees alike.

Soft Tissue and Bone Tumours

Author : WHO Classification of Tumours Editorial Board
Publisher : WHO Classification of Tumours
Page : 0 pages
File Size : 42,9 Mb
Release : 2020
Category : Medical
ISBN : 9283245024

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Soft Tissue and Bone Tumours by WHO Classification of Tumours Editorial Board Pdf

PLEASE NOTE: Text has been accidentally deleted from page 54 of this book. Please refer to the corrigenda (PDF file) posted on the Stylus Publishing web site or email [email protected] for an updated, printable page. ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. Since the previous edition, there have been changes based on recent molecular and genetic information, with impact on clinical practice.

Bone Cancer

Author : Dominique Heymann
Publisher : Academic Press
Page : 1080 pages
File Size : 49,6 Mb
Release : 2021-09-23
Category : Medical
ISBN : 9780323899901

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Bone Cancer by Dominique Heymann Pdf

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

Musculoskeletal Cancer Surgery

Author : Martin M. Malawer,Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 626 pages
File Size : 41,5 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306484070

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Musculoskeletal Cancer Surgery by Martin M. Malawer,Paul H. Sugarbaker Pdf

Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

Pediatric Bone and Soft Tissue Sarcomas

Author : Alberto S. Pappo
Publisher : Springer Science & Business Media
Page : 247 pages
File Size : 49,7 Mb
Release : 2005-12-31
Category : Medical
ISBN : 9783540294474

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Pediatric Bone and Soft Tissue Sarcomas by Alberto S. Pappo Pdf

The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.

AJCC Cancer Staging Manual

Author : Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow
Publisher : Springer Science & Business Media
Page : 386 pages
File Size : 51,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781475736564

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AJCC Cancer Staging Manual by Frederick L, Greene,David L. Page,Irvin D. Fleming,April G. Fritz,Charles M. Balch,Daniel G. Haller,Monica Morrow Pdf

The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

Sarcoma

Author : Peter F. M. Choong
Publisher : Springer Nature
Page : 345 pages
File Size : 40,6 Mb
Release : 2020-12-09
Category : Medical
ISBN : 9789811594144

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Sarcoma by Peter F. M. Choong Pdf

This book aims to compile an expert text on the multidisciplinary approach to treating sarcoma at a sarcoma centre. Separate chapters and sections highlight the specialist diagnostic and therapeutic approaches employed in treating bone and soft tissue sarcoma. This comprehensive book covers sarcoma and its management across specialties. It brings together the experience of the editor at a major centre for sarcoma management in Australia along with chapter contributions from various experts on the topic. The real-life, pragmatic approach is a distillation of the evidence and intends to make much of what is written translatable. This book serves as a reference for managing this tumour type and as an indispensable guide for daily use across the spectrum of providers.

Metastatic Bone Disease

Author : R. Lor Randall
Publisher : Springer
Page : 368 pages
File Size : 50,8 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781461456629

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Metastatic Bone Disease by R. Lor Randall Pdf

Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.

Soft Tissue and Bone Sarcoma

Author : Edwin Choy
Publisher : MDPI
Page : 157 pages
File Size : 52,8 Mb
Release : 2018-10-08
Category : Connective tissues
ISBN : 9783906980461

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Soft Tissue and Bone Sarcoma by Edwin Choy Pdf

This book is a printed edition of the Special Issue "Soft Tissue and Bone Sarcoma" that was published in Cancers

WHO Classification of Tumours of Soft Tissue and Bone

Author : Christopher D. M. Fletcher
Publisher : World Health Organization
Page : 468 pages
File Size : 55,8 Mb
Release : 2013
Category : Health & Fitness
ISBN : 9283224345

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WHO Classification of Tumours of Soft Tissue and Bone by Christopher D. M. Fletcher Pdf

At head of title: International Agency for Research on Cancer (IARC).

Bone Sarcoma

Author : Patrick P. Lin,Shreyaskumar Patel
Publisher : Springer Science & Business Media
Page : 277 pages
File Size : 40,7 Mb
Release : 2013-02-20
Category : Medical
ISBN : 9781461451945

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Bone Sarcoma by Patrick P. Lin,Shreyaskumar Patel Pdf

Bone Sarcoma is a succinct volume within the M.D. Anderson Cancer Care Series that summarizes the key elements of different specialties as they pertain to these cancers. It is a vital resource for physicians working with these uncommon yet fascinating bone sarcomas and uses a multidisciplinary team approach that is essential to maximizing a patient’s chances of a successful outcome. Written for physicians who have an interest in how the entire treatment process works and how their efforts are intertwined with those of their colleagues, Bone Sarcoma covers topics such as diagnostic techniques, treatment modalities, reconstruction and function, and a more globally oriented chapter geared towards algorithms for perioperative management and follow-up of patients. Designed for the busy practitioner, the esteemed M.D. Anderson Cancer Care Series offers an in-depth view of the current standard of care at M. D. Anderson, without extensive literature review or discussion of approaches not yet incorporated into routine clinical practice. Each chapter ends with an up-to-date list of suggested readings and a list of “key practice points” highlighting the most important principles presented. These books offer a clear picture of how M. D. Anderson is successfully treating patients today.

Imaging of Bone Tumors and Tumor-Like Lesions

Author : A. Mark Davies,Murali Sundaram,Steven J. James
Publisher : Springer Science & Business Media
Page : 694 pages
File Size : 44,9 Mb
Release : 2009-08-21
Category : Medical
ISBN : 9783540779841

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Imaging of Bone Tumors and Tumor-Like Lesions by A. Mark Davies,Murali Sundaram,Steven J. James Pdf

Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.

Musculoskeletal Diseases 2021-2024

Author : Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess
Publisher : Springer Nature
Page : 293 pages
File Size : 49,9 Mb
Release : 2021
Category : Electronic books
ISBN : 9783030712815

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Musculoskeletal Diseases 2021-2024 by Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess Pdf

This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.

Sarcomas

Author : Jonathan C. Trent, MD, PhD,Andrew E. Rosenberg, MD,Raphael Pollock, MD,Thomas F. Delaney, MD
Publisher : Springer Publishing Company
Page : 444 pages
File Size : 44,6 Mb
Release : 2020-09-23
Category : Medical
ISBN : 9780826148537

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Sarcomas by Jonathan C. Trent, MD, PhD,Andrew E. Rosenberg, MD,Raphael Pollock, MD,Thomas F. Delaney, MD Pdf

Sarcomas: Evidence-Based Diagnosisand Management is the most comprehensive clinical reference on sarcomas available to oncologists and trainees. Presenting a compilation of the current knowledge of specific soft tissue and bone sarcomas, this accessible resource on diagnosis and management is the most practical in the market. Led by the world’s foremost sarcomas experts in medical oncology, surgical oncology, radiation oncology, gynecologic oncology, orthopedic surgery, radiology, and pathology, the book addresses the general principles of each major medical discipline, provides details on each major sarcoma subtype, and presents the evidence for standard frontline, adjuvant, and novel treatment approaches such as immunotherapy, cellular therapies, and more. The book begins with general principles of diagnosis and management for each discipline in the field, covering specialties from medical oncology to radiology. Following the chapters on general principles, are chapters characterizing the most prevalent subtypes of sarcoma including their estimated incidence, common presenting symptoms, diagnostic approach, radiographic features and essential imaging, key diagnostic features, molecular characteristics, approaches to treatment, recommended follow up, the metastatic potential as well as evidence-based therapeutic approaches. Each chapter ends with a summary of caveats, clinical pearls, pitfalls, and solutions as well as a case study from the clinician’s point of view. The book ends with chapters focusing on new approaches to treatment and the development of therapeutics to combat sarcoma using immunotherapy, cellular therapy, and interventional radiology. Numerous tables and disease-based images support the text and provide key information for quick reference. Presenting detailed evidence and authoritative clinical guidance throughout, Sarcomas is a “one-stop” guide for any clinician diagnosing, treating, or managing patients suffering from these heterogenous diseases. Key Features: Provides the standards of care and evidence base for treatment of each major sarcoma subtype Covers all new treatment paradigms and FDA approvals Includes numerous quick reference tables and high-quality color images Presents over 20 practical case studies from leading clinicians in the field

Bone Tumors

Author : Jaime Paulos,Dominique G. Poitout
Publisher : Springer Nature
Page : 238 pages
File Size : 41,6 Mb
Release : 2021-07-15
Category : Medical
ISBN : 9781447175018

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Bone Tumors by Jaime Paulos,Dominique G. Poitout Pdf

This book reviews the latest techniques for diagnostics and treatments specific to bone and soft tissue tumors. It focuses on imaging and classification of the bone and soft tissue tumors and how histology and cytogenetic aspects can be used to identify tumors. Each chapter focuses on a specific type of tumor, providing a concise overview of relevant information on their characteristics along with the latest surgical and medical treatments available. Bone Tumors: Diagnosis and Therapy Today is a concise guide to successfully identifying and treating bone and soft tissue tumors, making it a valuable resource for practicing medical professionals and trainees who encounter these patients in their day-to-day practice.