Cancer Chemotherapy By Infusion

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Cancer Chemotherapy by Infusion

J.J. Lokich
Cancer Chemotherapy by Infusion Book PDF

Author : J.J. Lokich
Publisher : Springer Science & Business Media
Page : 762 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400931930

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Cancer Chemotherapy by Infusion by J.J. Lokich Pdf

Chemotherapy for-cancer is in a state of evolution. Because some cancers can now be cured with chemotherapy as a singular modality, this therapy can no longer be viewed as simply a palliative contribution. Chemotherapy has assumed an important role as an adjuvant to other modalities, including both surgery and radiation therapy. For some tumors, the primary application of chemotherapy in a combined modality approach to curative therapy has resulted in the application of less radical surgery while achieving substantial of relatively rare tumors such as cure rates. Nonetheless, with the exception childhood tumors, hematologic malignancies, and testicular cancer, the effec tiveness of chemotherapy in most tumors is severely limited. At the cellular level, greater understanding of the specific mechanism of tumor cell killing and of the phenomenon of drug resistance are elusive, critical ingredients in the improvement of effectiveness in cancer chemotherapy. Prolonging the exposure time of the tumor cell to drugs is a concept that was addressed in the early phases of the development of chemotherapy. How ever, technological limitations inhibited the broader application of chemother apy by infusion until recent years. Also, the convenience of intermittent ther apy on an outpatient basis, with the predominant theory of drug effect based on a dose response as well as the proven effectiveness of this schedule in some tumors, has slowed the process of subjecting infusion chemotherapy to the rigors of clinical trials.

Cancer Chemotherapy by Infusion

J.J. Lokich
Cancer Chemotherapy by Infusion Book PDF

Author : J.J. Lokich
Publisher : Springer
Page : 700 pages
File Size : 54,8 Mb
Release : 2011-10-12
Category : Medical
ISBN : 9401079323

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Cancer Chemotherapy by Infusion by J.J. Lokich Pdf

Chemotherapy for-cancer is in a state of evolution. Because some cancers can now be cured with chemotherapy as a singular modality, this therapy can no longer be viewed as simply a palliative contribution. Chemotherapy has assumed an important role as an adjuvant to other modalities, including both surgery and radiation therapy. For some tumors, the primary application of chemotherapy in a combined modality approach to curative therapy has resulted in the application of less radical surgery while achieving substantial of relatively rare tumors such as cure rates. Nonetheless, with the exception childhood tumors, hematologic malignancies, and testicular cancer, the effec tiveness of chemotherapy in most tumors is severely limited. At the cellular level, greater understanding of the specific mechanism of tumor cell killing and of the phenomenon of drug resistance are elusive, critical ingredients in the improvement of effectiveness in cancer chemotherapy. Prolonging the exposure time of the tumor cell to drugs is a concept that was addressed in the early phases of the development of chemotherapy. How ever, technological limitations inhibited the broader application of chemother apy by infusion until recent years. Also, the convenience of intermittent ther apy on an outpatient basis, with the predominant theory of drug effect based on a dose response as well as the proven effectiveness of this schedule in some tumors, has slowed the process of subjecting infusion chemotherapy to the rigors of clinical trials.

Concomitant Continuous Infusion Chemotherapy and Radiation

Marvin Rotman,C. Julian Rosenthal
Concomitant Continuous Infusion Chemotherapy and Radiation Book PDF

Author : Marvin Rotman,C. Julian Rosenthal
Publisher : Springer Science & Business Media
Page : 290 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642841866

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Concomitant Continuous Infusion Chemotherapy and Radiation by Marvin Rotman,C. Julian Rosenthal Pdf

The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives practicing physicians a detailed presentation of various therapeutic regimens which they could administer in their daily clinical practice. In the future, this innovative cancer treatment may lead to the decreased need for radical surgery and the increased ability to preserve organ function.

Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy

C. Julian Rosenthal,Marvin Rotman
Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy Book PDF

Author : C. Julian Rosenthal,Marvin Rotman
Publisher : Springer Science & Business Media
Page : 241 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461321972

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Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy by C. Julian Rosenthal,Marvin Rotman Pdf

The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.

Chemotherapy Protocols and Infusion Sequence

Iago Dillion Lima Cavalcanti
Chemotherapy Protocols and Infusion Sequence Book PDF

Author : Iago Dillion Lima Cavalcanti
Publisher : Springer Nature
Page : 330 pages
File Size : 44,5 Mb
Release : 2022-10-18
Category : Medical
ISBN : 9783031108396

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Chemotherapy Protocols and Infusion Sequence by Iago Dillion Lima Cavalcanti Pdf

This book aims to address the infusion sequence of the main protocols used in the treatment of varied solid cancers. Since an inadequate infusion sequence can compromise the patient's treatment, this work will provide support to professionals working in the field of oncology in assessing each chemotherapy infusion sequence. The introductory chapters present the definition, indication, and the risks and benefits of polypharmacy in cancer therapy, and discuss the importance of drug combination in cancer treatment. Chapter 2 focuses on the challenges and also the toxicity of combination therapy in cancer, while chapter 3 highlights the parameters that must be evaluated before defining the infusion sequence, such as pharmacodynamic and pharmacokinetic profiles, drugs’ stability when diluted or reconstituted, toxicological profile of each drug, among others. The remaining chapters are divided by type of cancer. The content is focused on solid tumors, dividing the chapters according to breast, gastrointestinal, genitourinary, gynecological, head and neck, lung, and neurological cancers. In each chapter the epidemiological profiles, pathophysiology, therapeutic modalities, and the main chemotherapy protocols are addressed, as well as efficacy studies and data on the infusion sequence of each mentioned protocol. This work will be a valuable resource to physicians, nurses, and pharmacists, and may help to improve health service practices.

Handbook of Cancer Treatment-Related Symptoms and Toxicities

Vamsidhar Velcheti,Salman R Punekar
Handbook of Cancer Treatment Related Symptoms and Toxicities Book PDF

Author : Vamsidhar Velcheti,Salman R Punekar
Publisher : Elsevier Health Sciences
Page : 355 pages
File Size : 48,9 Mb
Release : 2021-01-28
Category : Medical
ISBN : 9780323672993

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Handbook of Cancer Treatment-Related Symptoms and Toxicities by Vamsidhar Velcheti,Salman R Punekar Pdf

Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice. Presents a user-friendly overview of cancer treatment-related symptoms and toxicities management in a practical, easy-to-use format, allowing you to quickly find information in one convenient, concise resource. Covers systemic and radiation therapies, including chemotherapy, immunotherapy, targeted therapies, and radiation therapy, detailing symptoms of each toxicity to confirm your diagnosis. Overviews pharmacologic and non-pharmacologic approaches to symptom management. Offers recommendations for mitigating toxicities in high-risk patients. Discusses key topics such as management of infusion reactions, when the need for biopsy is warranted, and the unique challenges posed by novel immunotherapies.

Adjuvant Therapy for Breast Cancer

Monica Castiglione,Martine J. Piccart
Adjuvant Therapy for Breast Cancer Book PDF

Author : Monica Castiglione,Martine J. Piccart
Publisher : Springer Science & Business Media
Page : 483 pages
File Size : 50,7 Mb
Release : 2009-07-11
Category : Medical
ISBN : 9780387751153

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Adjuvant Therapy for Breast Cancer by Monica Castiglione,Martine J. Piccart Pdf

Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Handbook of Cancer Chemotherapy

Roland T. Skeel,Samir N. Khleif
Handbook of Cancer Chemotherapy Book PDF

Author : Roland T. Skeel,Samir N. Khleif
Publisher : Lippincott Williams & Wilkins
Page : 896 pages
File Size : 45,7 Mb
Release : 2011
Category : Medical
ISBN : 9781608317820

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Handbook of Cancer Chemotherapy by Roland T. Skeel,Samir N. Khleif Pdf

Skeel's Handbook of Cancer Chemotherapy combines in one place the most current rationale and specific details necessary to safely administer chemotherapy for most adult cancers. The handbook is a practical, diseased-focused pocket reference that emphasizes the best current medical practice as it relates to the delivery of chemotherapeutic drugs. By focusing on specific plans for treatment, the book is an invaluable resource for the daily care of cancer patients.

Physicians' Cancer Chemotherapy Drug Manual

Edward Chu,Vincent T. DeVita
Physicians Cancer Chemotherapy Drug Manual Book PDF

Author : Edward Chu,Vincent T. DeVita
Publisher : Jones & Bartlett Learning
Page : 564 pages
File Size : 48,6 Mb
Release : 2007
Category : Medical
ISBN : 0763743089

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Physicians' Cancer Chemotherapy Drug Manual by Edward Chu,Vincent T. DeVita Pdf

Includes free CD-ROM! Completely revised and updated for 2007, this practical handbook is an up-to-date guide to all aspects of cancer chemotherapy. The book provides a comprehensive, easy to use catalogue of over 100 drugs-both on- and off-label-commonly used in cancer treatment, including several new agents (recently or about to be FDA approved). A section on Common Chemotherapy Regimens provides a quick reference to management of specific cancers, arranged alphabetically. A comprehensively revised introductory chapter on Principles of Chemotherapy offers a concise, current overview of the field. Special features include: Special chapter profiling anti-emetic drugs Diagrams of drug structures and pathways Complete discussion of clinical pharmacology, indications, and dosages Coverage of toxicity and interactions Separate chapter on chemotherapy regimens for specific cancers Overview of basic principles of cancer drug therapy Easy to load and use CD-ROM version PDA version of Physicians' Cancer Chemotherapy Drug Manual also available!

Infusion Chemotherapy--irradiation Interactions

C. Julian Rosenthal,Marvin Rotman
Infusion Chemotherapy irradiation Interactions Book PDF

Author : C. Julian Rosenthal,Marvin Rotman
Publisher : North Holland
Page : 0 pages
File Size : 44,5 Mb
Release : 1998
Category : Cancer
ISBN : 0444826084

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Infusion Chemotherapy--irradiation Interactions by C. Julian Rosenthal,Marvin Rotman Pdf

Explores the scientific basis of the clinically significant synergistic therapeutic interactions between chemotherapy and irradiation therapy. Modified-outline format.

Induction Chemotherapy

Karl Reinhard Aigner,Frederick O. Stephens
Induction Chemotherapy Book PDF

Author : Karl Reinhard Aigner,Frederick O. Stephens
Publisher : Springer
Page : 506 pages
File Size : 48,7 Mb
Release : 2016-05-27
Category : Medical
ISBN : 9783319287737

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Induction Chemotherapy by Karl Reinhard Aigner,Frederick O. Stephens Pdf

This book presents the full range of management techniques and practices used in induction chemotherapy – both systemic and locoregional - by experienced international groups within one accessible volume. It provides the latest information on the pioneering and cutting-edge practices employed in different institutions and documents the advantages of integrated treatment schedules. All those responsible for treating patients with locally advanced cancers may find new, interesting aspects of locoregional cancer management and will find this book to be an invaluable source of up-to-date information. Throughout the world, induction chemotherapy is being used as part of an integrated plan of management for locally advanced, solid tumors, while systemic chemotherapy is most commonly used to shrink primarily non-operable tumors. In cases of poorly or nonresponsive tumors, attempts have been made to administer chemotherapeutics via the arterial route in order to achieve higher localized drug exposure and response rates. Such therapies are being practiced worldwide in independent, remote departments in universities, teaching hospitals and clinical schools. Frequently, however, these teams remain relatively unaware of the work being done in other institutions, which may slow further progress.

Vascular Perfusion in Cancer Therapy

K. Schwemmle,K. Aigner
Vascular Perfusion in Cancer Therapy Book PDF

Author : K. Schwemmle,K. Aigner
Publisher : Springer Science & Business Media
Page : 487 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642820250

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Vascular Perfusion in Cancer Therapy by K. Schwemmle,K. Aigner Pdf

Substantial relief of discomfort may be anticipated by most patients suffering from pelvic and lower-extremity pain who are treated by arterial infusion of nitrogen mustard. Seventy-three patients with intractable pain secondary to malignancy arising in the pelvis received 83 percutaneous pelvic arterial infusions of this drug. Sixty infusions (72%) resulted in marked relief from pain for periods averaging 6-8 weeks. Advantages of the procedure are low toxicity, relative simplicity and availability of technique, and an acceptable rate of complications with minimal morbidity. Patients experiencing satisfactory results may expect significant relief from a second infusion for recurrent pain. The most rewarding result is the freedom from the cyclic return of pain characterized by oral and intramuscular analgesic therapy. Little or no relief can be expected in patients with pain caused by compression fractures of the vertebrae, or where the tumor burden is so great that adequate perfusion of the involved nerves is not possible. One should consider this procedure for controlling pain before resorting to the more dangerous and potentially disabling techniques of spinal cordotomy or intrathecal alcohol injection. References Bateman JR, Hazen JG, Stolinsky DC, Steinfeld JL (1966) Advanced carcinoma of the cervix treated by intra-arterial methotrexate. Am J Obstet Gynecol 96: 181-187 Calabresi P, Parks RW Jr (1970) Alkylating agents, antimetabolites, hormones. and other antiproliferative agents. In: Goodman LS, Gilman A (eds) The pharmacological basis of therapeutics, 4th edn.

Pocket Guide to Chemotherapy Protocols

Edward Chu
Pocket Guide to Chemotherapy Protocols Book PDF

Author : Edward Chu
Publisher : Jones & Bartlett Learning
Page : 188 pages
File Size : 50,8 Mb
Release : 2007
Category : Cancer
ISBN : 0763743100

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Pocket Guide to Chemotherapy Protocols by Edward Chu Pdf

Medicine

The Cancer Chemotherapy Handbook

David S. Fischer,Mary Kathryn Tish Knobf,Henry J. Durivage
The Cancer Chemotherapy Handbook Book PDF

Author : David S. Fischer,Mary Kathryn Tish Knobf,Henry J. Durivage
Publisher : Unknown
Page : 650 pages
File Size : 43,7 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015040596911

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The Cancer Chemotherapy Handbook by David S. Fischer,Mary Kathryn Tish Knobf,Henry J. Durivage Pdf

Concisely written, yet comprehensive in scope, this new edition is a practical guide to the medical care and chemotherapeutic treatment of cancer patients. It is formatted for easy access to the more than 85 specific drugs currently used in cancer treatment. 12 illus.

Avoiding Cancer One Day at a Time

Lynne Eldridge,Lynne Stoesz-Eldridge,David Borgeson
Avoiding Cancer One Day at a Time Book PDF

Author : Lynne Eldridge,Lynne Stoesz-Eldridge,David Borgeson
Publisher : Avoiding Cancer Now
Page : 322 pages
File Size : 45,9 Mb
Release : 2006-12
Category : Family & Relationships
ISBN : 9781592981595

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Avoiding Cancer One Day at a Time by Lynne Eldridge,Lynne Stoesz-Eldridge,David Borgeson Pdf

The mortality rate from cancer hasn't changed in 60 years despite the billions invested to find a cure. Avoiding Cancer One Day At A Time provides solid, practical advice for preventing cancer by avoiding carcinogens and implementing lifestyle/dietary practices that modify cancer causing factors. Combining their experience in family medicine and epidemiology with their passion for disease prevention, the authors provide the most up to date and effective advice for preventing cancer from developing in ourselves and our loved ones. Many ?how to? examples for preventing cancer by being environmentally aware, avoiding infections, living the proper lifestyle and getting the proper nutrition are provided. Chapter by chapter summaries and listings of the latest cancer prevention web sites are great references. Worksheets assist readers in implementing the advice in very tangible ways, and the recipe collection of cancer avoiding meals is a winner!