Cancer Research

Author : Anonim
Publisher : Academic Press
Page : 384 pages
File Size : 42,7 Mb
Release : 2021-04-13
Category : Medical
ISBN : 9780128241592

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Autophagy and Senescence in Cancer Therapy by Anonim Pdf

Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more. Addresses the relationship between autophagy and senescence in cancer therapy Covers autophagy and senescence in tumor dormancy Explores autophagy and senescence in disease recurrence

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 44,5 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Anonim
Publisher : Unknown
Page : 24 pages
File Size : 40,6 Mb
Release : 196?
Category : Cancer
ISBN : OCLC:221570051

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Answers to Your Questions about Cancer by Anonim Pdf

Author : Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi
Publisher : Elsevier
Page : 700 pages
File Size : 51,9 Mb
Release : 2012-05-18
Category : Medical
ISBN : 9780123978363

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Recent Advances in Cancer Research and Therapy by Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi Pdf

Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Author : National Cancer Institute (U.S.)
Publisher : Unknown
Page : 56 pages
File Size : 49,7 Mb
Release : 1979
Category : Cancer
ISBN : MINN:30000005198035

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NCI Fact Book by National Cancer Institute (U.S.) Pdf

Author : Dragos Balasoiu,Keith Scott-Mumby
Publisher : Scott-Mumby Wellness is
Page : 0 pages
File Size : 49,5 Mb
Release : 2011-06
Category : Cancer
ISBN : 0983878404

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Cancer Research Secrets by Dragos Balasoiu,Keith Scott-Mumby Pdf

The author presents background information and his perspective on various alternative and holistic treatment methods for cancer.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 45,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Miroslava Čuperlović-Culf
Publisher : Elsevier
Page : 446 pages
File Size : 47,8 Mb
Release : 2012-12-17
Category : Medical
ISBN : 9781908818263

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NMR Metabolomics in Cancer Research by Miroslava Čuperlović-Culf Pdf

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Author : Anonim
Publisher : Elsevier
Page : 332 pages
File Size : 47,6 Mb
Release : 2023-09-12
Category : Medical
ISBN : 9780443192814

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Advances in Cancer Research by Anonim Pdf

Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Author : Pat Price,Karol Sikora
Publisher : CRC Press
Page : 1029 pages
File Size : 45,6 Mb
Release : 2020-11-24
Category : Medical
ISBN : 9780429649004

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Treatment of Cancer by Pat Price,Karol Sikora Pdf

Treatment of Cancer is a multi-author work and comprehensive guide on modern cancer treatment that aims to give clinician and student alike the framework for an integrated approach to patient care, including radiotherapy, chemotherapy, and surgery. Much information is presented in tables and charts for easy assimilation, and clear algorithms for patient pathways are included to make decisions straightforward while allowing for sound clinical judgement.

Author : Bernard W. Stewart,Chris Wild
Publisher : Unknown
Page : 0 pages
File Size : 45,9 Mb
Release : 2014-02
Category : Cancer
ISBN : 9283204336

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World Cancer Report 2014 (Print + EPUB) by Bernard W. Stewart,Chris Wild Pdf

"This book from the International Agency for Research on Cancer the specialized cancer agency of the World Health Organization provides a unique global view of cancer including cancer patterns causes and prevention. The World Cancer Report series is recognized as an authoritative source of global perspective and information on cancer. The first volume appeared in 2003 and the second in 2008. This third volume in the series encompasses both established knowledge and recent research achievement. World Cancer Report provides a professional multidisciplinary assessment of all aspects of the geographical distribution biology etiology prevention and control of cancer predicated on research. The concise nature of the text and the high graphic content (hundreds of colour maps diagrams and photographs) make the publication accessible to a broad readership. World Cancer Report is designed to provide non-specialist health professionals and policy-makers with a balanced understanding of cancer control and to provide established cancer professionals with insights about recent development. The book includes chapters in which distinguished scientists from around the world provide a broad overview of established knowledge and then emphasize research activity and progress. In addition text boxes distributed throughout the book provide short in-depth discussions of selected questions or topics. A new feature of this volume is the inclusion of Perspectives considering the future development of different aspects of cancer research written by those whose record of outstanding achievement qualifies them as individuals having unique vision. Includes more than 60 chapters with contributions from more than 150 distinguished scientists from around the world with information on: . Cancer Worldwide . Cancer Etiology . Cancer Biology . Cancer Prevention . Cancer by Organ Site . Cancer Control Also available: Online version (EPUB): World Cancer Report 2014 (EPUB) version Print: World Cancer Report 2014

Author : Norman E. Breslow,N. E. Day
Publisher : Unknown
Page : 352 pages
File Size : 52,7 Mb
Release : 1980
Category : Cancer
ISBN : PSU:32239001595244

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The Analysis of Case-control Studies by Norman E. Breslow,N. E. Day Pdf

Author : H. Acker,J. Carlsson,R. Durand,R.M. Sutherland
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642823404

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Spheroids in Cancer Research by H. Acker,J. Carlsson,R. Durand,R.M. Sutherland Pdf

Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supply. As a consequence, the cancer cells grow in a three-dimensional pattern in atypical microenvironments which include physical, chemical, and nutritional stresses. Necrosis often develops some distance away from the blood vessels. In association with an inherent instability in malignant cell populations, and also because of the changing micromilieu, significant cellular heteroge neity emerges with regard to various phenotypic characteristics. Both biological behavior and responses to therapeutic agents can be affected. A variety of in vitro and in vivo experimental models exist for research on properties of cancer cells during growth. The multicell spheroid model was developed as a system of intermediate complexity in which three dimensional growth of cells enhances cell-cell interactions and creates micro environments that simulate the conditions in intervascular microregions of tumors or microme tastatic foci. Spheroids may change their cellular characteristics with changing environments during growth. These can be studied under controlled conditions in vitro. Interest in details of experimental methods for this model system stimulated the organization of the First International Conference in Rochester, NY in 1980, the Proceedings of which were summarized in Cancer Research in 1981. Since then there has been a rapid increase in the use of this model system, and increased research on the significance of cell-cell and cell-microenvironment interactions in biology in general.

Author : International Union against Cancer. Committee on Public Education,Michael S. Goodstadt
Publisher : Springer
Page : 118 pages
File Size : 46,9 Mb
Release : 1967
Category : Medical
ISBN : NWU:35558001644232

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Public Education about Cancer by International Union against Cancer. Committee on Public Education,Michael S. Goodstadt Pdf

This monograph is essentially the outcome of corporate endeavour on the part of members of the Committee on Public Education of the International Union against Cancer, from the decision taken in September 1963, via a lengthy and arduous rework ing of the first draft in Philadelphia in 1964 to its final editorial meeting in September 1965. In between there has been a continuous exchange of ideas, suggestions, advice and material for inclusion. Nevertheless, as chairman I should be remiss if I did not acknowledge the Committee's indebtedness to Mr. MICHAEL S. GOOD STADT, formerly of the University of Manchester, who worked with me in Manchester and undertook the painstaking search of sources of published information and compiled the draft on which this monograph is based. If there are omissions from the bibliography, it is not for want of industry in seeking them out: our difficulty has been to obtain original material from certain sources. We hope that the material assembled here will both offer useful guidance to those engaged in public education about cancer and provide a baseline from which future research in this neglected field may stem. Committee on Public Education International Union Against Cancer Chairman: JOHN WAKEFIELD, U. K. Members: Dr F. DE AMESTI, Chile, Mr. A. J. BROWN, Australia, Dr. J. COURTIAL, France, Mr. T. CRAMER, Denmark, Dr. L. MEINSMA, The Netherlands, Dr. R. A. MUSTARD, Canada, Dr. L. V. ORLOVSKY, U. S. S. R. , Dr. J. C.

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
Publisher : National Academies Press
Page : 151 pages
File Size : 49,8 Mb
Release : 2010-10-22
Category : Medical
ISBN : 9780309163354

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Transforming Clinical Research in the United States by Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation Pdf

An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.