Cardiotoxicity Induced By Radiotherapy And Or Chemotherapy After Cancer Treatment

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Cardiotoxicity Induced by Radiotherapy and/or Chemotherapy After Cancer Treatment.

Author : Virginie Monceau,Omid Azimzadeh,Marjan Boerma,Nadia Pasinetti
Publisher : Frontiers Media SA
Page : 139 pages
File Size : 55,8 Mb
Release : 2022-12-23
Category : Medical
ISBN : 9782832509531

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Cardiotoxicity Induced by Radiotherapy and/or Chemotherapy After Cancer Treatment. by Virginie Monceau,Omid Azimzadeh,Marjan Boerma,Nadia Pasinetti Pdf

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology

Author : Imteyaz Qamar,Pawan Kumar Maurya
Publisher : Academic Press
Page : 278 pages
File Size : 53,8 Mb
Release : 2022-05-26
Category : Science
ISBN : 9780323904629

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Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology by Imteyaz Qamar,Pawan Kumar Maurya Pdf

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

Anticancer Treatments and Cardiotoxicity

Author : Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi
Publisher : Academic Press
Page : 470 pages
File Size : 44,7 Mb
Release : 2016-11-11
Category : Medical
ISBN : 9780128026472

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Anticancer Treatments and Cardiotoxicity by Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi Pdf

Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Manual of Cardio-oncology

Author : Chiara Lestuzzi,Stefano Oliva,Francesco Ferraù
Publisher : Springer
Page : 473 pages
File Size : 50,7 Mb
Release : 2017-10-13
Category : Medical
ISBN : 9783319402369

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Manual of Cardio-oncology by Chiara Lestuzzi,Stefano Oliva,Francesco Ferraù Pdf

This concise and handy manual provides straightforward, up-to-date guidance for cardiologists and other practitioners on the management of cancer patients with cardiac problems, whether they be due to the cancer itself or to antineoplastic treatment. Detailed attention is devoted to the various forms of cardiotoxicity associated with chemotherapy and radiotherapy. The drugs commonly responsible for each toxicity are identified and clear advice is offered on monitoring techniques and treatment approaches. In addition, the issue of cardiotoxicity due to cancer treatment in particular patient groups – children, the elderly, and those with pre-existing cardiac disease – is addressed separately, with guidance on when and how antineoplastic (and/or cardiological) treatments should be modified. Further sections describe the correct responses to cardiac problems secondary to the cancer itself, including thromboembolic disorders and electrolyte imbalances, and the diagnosis, treatment, and follow-up of cardiac tumors. A closing section considers how to improve cooperation between oncologists, cardiologists, and general practitioners to ensure that cancer patients’ cardiovascular needs are met in a multidisciplinary approach.

Cancer Treatment and the Heart

Author : Franco M. Muggia,Michael D. Green,James L. Speyer
Publisher : Unknown
Page : 416 pages
File Size : 40,8 Mb
Release : 1992
Category : Literary Criticism
ISBN : UOM:39015029195248

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Cancer Treatment and the Heart by Franco M. Muggia,Michael D. Green,James L. Speyer Pdf

A foundational investigation of disorders of the heart resulting from cancer treatment, with conclusions about common mechanisms. Seventeen contributed chapters are arranged in five parts: cytotoxic myocardial disease--preclinical study, cytotoxic myocardial disease--clinical study, myocardial disease--radiation and biologics, pericardial disease, and other cardiovascular disease. Annotation copyright by Book News, Inc., Portland, OR

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 51,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Cancer and the Heart

Author : Michael S. Ewer
Publisher : PMPH-USA
Page : 508 pages
File Size : 44,5 Mb
Release : 2013
Category : Drugs
ISBN : 1607950405

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Cancer and the Heart by Michael S. Ewer Pdf

The book begins with the basic science behind the medical applications of the knowledge: cardiovascular biology, pathways, and their relationship to cancer treatment and principles of chemotherapy and immunotherapy. The second section consists of an overview and classification of anti-cancer drugs and a look at their cardiotoxicity. The third section looks at cardiac imaging in the cancer patient, including cardiac ultrasound, Doppler imaging, nuclear imaging, magnetic resonance imaging, and computed tomography in the cancer patient. In section four, management of cardiac disease in the cancer patient is discussed, including cardiac rhythm disturbances and heart failure. Cardiac emergencies and interventions are described as is preoperative assessment of the cancer patient for non- cardiovascular surgery. The final section includes a range of topics such as the pericardium, cardiovascular effects of endocrine treatments, primary cardiac tumors and malignancies of the myocardium and pericardium. Cardiac monitoring during clinical trials and pulmonary concerns are also addressed, as are psychosocial, social, economic, and legal issues of the cancer patient with heart disease.

Cardio-oncology

Author : Gretchen G. Kimmick,Daniel J. Lenihan (MD),Douglas B. Sawyer,Erica L. Mayer,Dawn L. Hershman
Publisher : Unknown
Page : 128 pages
File Size : 46,6 Mb
Release : 2017
Category : Heart
ISBN : 3319430955

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Cardio-oncology by Gretchen G. Kimmick,Daniel J. Lenihan (MD),Douglas B. Sawyer,Erica L. Mayer,Dawn L. Hershman Pdf

Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: " Cardiac complications in patients receiving cancer therapy " The treatment of cancer in patients with cardiovascular disease " The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

Cardiotoxicity of Oncologic Treatments

Author : Manuela Fiuza
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 54,6 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9789535102731

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Cardiotoxicity of Oncologic Treatments by Manuela Fiuza Pdf

The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.

Cardio-Oncology: From Bench to Bedside

Author : Jun-ichi Abe,Anil K. Sood,James Martin
Publisher : Frontiers Media SA
Page : 113 pages
File Size : 48,8 Mb
Release : 2019-05-17
Category : Electronic
ISBN : 9782889458752

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Cardio-Oncology: From Bench to Bedside by Jun-ichi Abe,Anil K. Sood,James Martin Pdf

Cardio-oncology is a medical subspecialty concerned with the diagnosis and treatment of cardiovascular disease (CVD) and organ failure mediated by micro- to macro-circulation defects in cancer patients and survivors. The risk of CVD in cancer survivors is eight times higher than the general population, and the relative risk of coronary artery disease and heart failure (HF) is 10 times and 15 times higher, respectively, compared to their siblings without cancer. It is important to note that cancer treatments including chemotherapy and radiation can lead to both short- (< 1 year) and long-term (> 5 years) cardiovascular complications. Previously, Dr. Edward T.H. Yeh initiated the MD Anderson Practice (MAP) project, and published 16 MAPs to provide the current best practice we considered at UT MD Anderson. As shown in these MAPs, one of the key issues of cardio-oncology practice and science is how we can allow cancer patients to receive maximum and uninterrupted treatments for cancer while protecting them from cancer therapy-mediated cardiovascular complications. Therefore, it is crucial to understand not only pathophysiology of CVD, but also mechanistic insights of how each cancer treatment can control cancer growth and metastasis. Without having the profound knowledge in the pathophysiological, clinical and epidemiologic aspects of cardiovascular complications of existing cancer therapy, it is impossible to establish the strong evidence-based strategies and approaches for both short- and long-term cardiovascular complications after cancer treatment. In addition, we believe that cardio-oncology science should not be restricted to deal with the side effects of each specific cancer drug, because many common cardiovascular phenotypes among the different cancer treatments are also observed. This Research Topic provides a comprehensive overview from both of the current research and practice, and a platform for obtaining the logical and up-to-date treatment and prevention of CVD in cancer patients and survivors.

Cardiovascular Sequelae of Chemotherapy and Radiotherapy in Cancer Survivors: Current evidence and perspectives

Author : Antonella Lombardo,Péter Ferdinandy,Rod Skinner
Publisher : Frontiers Media SA
Page : 114 pages
File Size : 49,6 Mb
Release : 2023-07-05
Category : Medical
ISBN : 9782832529058

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Cardiovascular Sequelae of Chemotherapy and Radiotherapy in Cancer Survivors: Current evidence and perspectives by Antonella Lombardo,Péter Ferdinandy,Rod Skinner Pdf

Cardiac Management of Oncology Patients

Author : Gonzalo Baron Esquivias,Riccardo Asteggiano
Publisher : Springer
Page : 259 pages
File Size : 45,9 Mb
Release : 2015-05-25
Category : Medical
ISBN : 9783319158082

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Cardiac Management of Oncology Patients by Gonzalo Baron Esquivias,Riccardo Asteggiano Pdf

This book is designed for clinical cardiologists and other physicians working with cardiac patients, where specific specialized teams of cardio-oncologists are not available and who are called to perform a clinical consultation to evaluate both the cardiac condition and the eligibility for chemotherapy or radiotherapy treatment, and to evaluate if a cancer treatment produces toxic effects on a patient treated with chemo or radiotherapy and if appearance of new symptoms is due to this treatment. In recent years, progress in oncologic therapy has resulted in important developments and the prognostic improvement of patients with malignancy. The cornerstone of chemotherapy are the anthracyclines (and the analogue Mitoxantrone), that are direct cellular toxic agents and that are among the most powerful anti-neoplastic drugs, but their cardiac toxicity is well known. Significant breakthroughs in cancer therapy have also been achieved with the introduction of signalling inhibitors, such as VEGF inhibitors, HERB2 inhibitors or TK inhibitors used alone or in combination with direct cellular toxic drugs. However, these signalling inhibitors may interact also with cardiovascular signalling and therefore may have functional or structural effects on the myocardium. This can be permanent or reversible, with impairment of the global conditions and important side effects, and increase both morbidity and mortality and worsening of quality of life. Chemotherapy and radiotherapy can have acute detrimental effects that can be present for years after treatment and that can lead to cardiac consequences also after long periods of no clinic sequelae. Patient numbers with cancer problems will dramatically increase in the next years and thus every cardiologist will need to have the correct information and the skills to manage these situations in the correct way. This book will provide these tools for them.

Clinical Cases in Cardio-Oncology

Author : Atooshe Rohani
Publisher : Springer Nature
Page : 122 pages
File Size : 55,6 Mb
Release : 2021-04-26
Category : Medical
ISBN : 9783030711559

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Clinical Cases in Cardio-Oncology by Atooshe Rohani Pdf

This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with ​cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with ​cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.

Cardiac Toxicity After Treatment for Childhood Cancer

Author : J. Timothy Bricker,Daniel M. Green,Giulio J. D'Angio
Publisher : Wiley-Liss
Page : 148 pages
File Size : 51,6 Mb
Release : 1993-11-15
Category : Medical
ISBN : UOM:39015033110480

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Cardiac Toxicity After Treatment for Childhood Cancer by J. Timothy Bricker,Daniel M. Green,Giulio J. D'Angio Pdf

Prominent contributors present articles dealing with such topics as the pathology of radiation and anthracycline-related cardiac injury, pathophysiology of anthracycline cardiomyopathy, results of various strategies for screening survivors for the presence of treatment-related cardiomyopathy and methods under development that may reduce the risk of anthracycline-related cardiac injury.

Annals of Oncology

Author : European Society for Medical Oncology
Publisher : Springer
Page : 218 pages
File Size : 47,8 Mb
Release : 2013-12-14
Category : Medical
ISBN : 9781489973054

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Annals of Oncology by European Society for Medical Oncology Pdf