Catalytic Arylation Methods

Author : Anthony J. Burke,Carolina Silva Marques
Publisher : John Wiley & Sons
Page : 530 pages
File Size : 53,6 Mb
Release : 2015-02-09
Category : Science
ISBN : 9783527335183

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Catalytic Arylation Methods by Anthony J. Burke,Carolina Silva Marques Pdf

This "hands-on" approach to the topic of arylation consolidates the body of key research over the last ten years (and up to around 2014) on various catalytic methods which involve an arylation process. Clearly structured, the chapters in this one-stop resource are arranged according to the reaction type, and focus on novel, efficient and sustainable processes, rather than the well-known and established cross-coupling methods. The entire contents are written by two authors with academic and industrial expertise to ensure consistent coverage of the latest developments in the field, as well as industrial applications, such as C-H activation, iron and gold-catalyzed coupling reactions, cycloadditions or novel methodologies using arylboron reagents. A cross-section of relevant tried-and-tested experimental protocols is included at the end of each chapter for putting into immediate practice, along with patent literature. Due to its emphasis on efficient, "green" methods and industrial applications of the products concerned, this interdisciplinary text will be essential reading for synthetic chemists in both academia and industry, especially in medicinal and process chemistry.

Author : Lutz Ackermann
Publisher : John Wiley & Sons
Page : 561 pages
File Size : 44,9 Mb
Release : 2009-04-22
Category : Science
ISBN : 9783527627332

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Modern Arylation Methods by Lutz Ackermann Pdf

Today, arylation methods are belonging to the most important reaction types in organic synthesis. Lutz Ackermann, a young and ambitious professor has gathered a number of top international authors to present the first comprehensive book on the topic. Starting from a historical review, the book covers hot topics like Palladium-catalyzed arylation of N-H and alpha-C-H-acidic Bonds, Copper-catalyzed arylation of N-H and O-H Bonds, direct arylation reactions, carbanion aromatic synthesis, arylation reactions of alkenes, alkynes and much more. This compact source of high quality information is indispensable to synthetic chemists and those working in the pharmaceutical and chemical industry.

Author : Pierre H. Dixneuf,Henri Doucet
Publisher : Springer
Page : 264 pages
File Size : 49,9 Mb
Release : 2015-12-18
Category : Science
ISBN : 9783319246307

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C-H Bond Activation and Catalytic Functionalization I by Pierre H. Dixneuf,Henri Doucet Pdf

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal.

Author : Jin-Quan Yu
Publisher : Thieme
Page : 756 pages
File Size : 46,7 Mb
Release : 2016-05-23
Category : Science
ISBN : 9783131766816

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Science of Synthesis: Catalytic Transformations via C-H Activation Vol. 1 by Jin-Quan Yu Pdf

The reference work Science of Synthesis: Catalytic Transformations via C-H Activation covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 1 concerns the formation of C-C bonds by both arene and hetarene C-H activation. For the arenes the material is subdivided into arylation (using palladium(0), palladium(II)/palladium(IV), palladium(II), and ruthenium(II) catalysts), vinylation (using various palladium and ruthenium(III) catalysts), and alkylation (using various metal catalysts in combination with either functionalized alkanes or alkenes). For the hetarenes, the related coupling strategies are covered as a single topic using a variety of metal catalysts and coupling partners.

Author : Tharmalingam Punniyamurthy,Anil Kumar
Publisher : John Wiley & Sons
Page : 1209 pages
File Size : 46,8 Mb
Release : 2023-03-28
Category : Science
ISBN : 9781119774150

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Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes by Tharmalingam Punniyamurthy,Anil Kumar Pdf

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles A comprehensive guide to recent advances in this field Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds. Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches. Readers of Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set will also find: A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies A leading team of international authors in C-H bond functionalization Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.

Author : Michelangelo Gruttadauria,Francesco Giacalone
Publisher : John Wiley & Sons
Page : 720 pages
File Size : 55,8 Mb
Release : 2011-09-27
Category : Science
ISBN : 9780470641361

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Catalytic Methods in Asymmetric Synthesis by Michelangelo Gruttadauria,Francesco Giacalone Pdf

This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.

Author : Thomas Colacot
Publisher : Royal Society of Chemistry
Page : 914 pages
File Size : 44,7 Mb
Release : 2015
Category : Science
ISBN : 9781849738965

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New Trends in Cross-Coupling by Thomas Colacot Pdf

Following on from its recognition in the 2010 Nobel Prize for Chemistry, contributors from across the globe present the latest cross-coupling trends in both academia and industry.

Author : Xiao-Feng Wu
Publisher : John Wiley & Sons
Page : 596 pages
File Size : 46,5 Mb
Release : 2016-03-07
Category : Technology & Engineering
ISBN : 9783527338887

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Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation by Xiao-Feng Wu Pdf

Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Author : Maurizio Benaglia,Alessandra Puglisi
Publisher : John Wiley & Sons
Page : 492 pages
File Size : 50,7 Mb
Release : 2020-04-06
Category : Technology & Engineering
ISBN : 9783527345090

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Catalyst Immobilization by Maurizio Benaglia,Alessandra Puglisi Pdf

A comprehensive resource on techniques and applications for immobilizing catalysts Catalyst Immobilization: Methods and Applications covers catalyst immobilization topics including technologies, materials, characterization, chemical activity, and recyclability. The book also presents innovative applications for supported catalysts, such as flow chemistry and machine-assisted organic synthesis. Written by an international panel of expert contributors, this book outlines the general principles of catalyst immobilization and explores different types of supports employed in catalyst heterogenization. The book?s chapters examine the immobilization of chiral organocatalysts, reactions in flow reactors, 3D printed devices for catalytic systems, and more. Catalyst Immobilization offers a modern vision and a broad and critical view of this exciting field. This important book: -Offers a guide to supported and therefore recyclable catalysts, which is one of the most important tools for developing a highly sustainable chemistry -Presents various immobilization techniques and applications -Explores new trends, such as 3D printed devices for catalytic systems -Contains information from a leading international team of authors Written for catalytic chemists, organic chemists, process engineers, biochemists, surface chemists, materials scientists, analytical chemists, Catalyst Immobilization: Methods and Applications presents the latest developments and includes a review of the innovative trends such as flow chemistry, reactions in microreactors, and beyond.

Author : David C. Blakemore,Paul M. Doyle,Yvette M. Fobian
Publisher : Royal Society of Chemistry
Page : 474 pages
File Size : 53,8 Mb
Release : 2016
Category : Drug development
ISBN : 9781849738033

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Synthetic Methods in Drug Discovery by David C. Blakemore,Paul M. Doyle,Yvette M. Fobian Pdf

The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.

Author : Duprez Daniel,Cavani Fabrizio
Publisher : World Scientific
Page : 1036 pages
File Size : 40,6 Mb
Release : 2014-07-24
Category : Science
ISBN : 9781783263349

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Handbook Of Advanced Methods And Processes In Oxidation Catalysis: From Laboratory To Industry by Duprez Daniel,Cavani Fabrizio Pdf

This book offers a comprehensive overview of the most recent developments in both total oxidation and combustion and also in selective oxidation. For each topic, fundamental aspects are paralleled with industrial applications. The book covers oxidation catalysis, one of the major areas of industrial chemistry, outlining recent achievements, current challenges and future opportunities. One distinguishing feature of the book is the selection of arguments which are emblematic of current trends in the chemical industry, such as miniaturization, use of alternative, greener oxidants, and innovative systems for pollutant abatement. Topics outlined are described in terms of both catalyst and reaction chemistry, and also reactor and process technology.

Author : Gwilherm Evano,Nicolas Blanchard
Publisher : John Wiley & Sons
Page : 682 pages
File Size : 50,8 Mb
Release : 2013-09-23
Category : Science
ISBN : 9781118690475

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Copper-Mediated Cross-Coupling Reactions by Gwilherm Evano,Nicolas Blanchard Pdf

Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.

Author : Robert Bernard Anderson,Peter T. Dawson
Publisher : Unknown
Page : 128 pages
File Size : 41,8 Mb
Release : 1976
Category : Catalysis
ISBN : OCLC:610274658

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Experimental Methods in Catalytic Research by Robert Bernard Anderson,Peter T. Dawson Pdf

Author : Anonim
Publisher : Academic Press
Page : 346 pages
File Size : 51,8 Mb
Release : 2018-01-02
Category : Science
ISBN : 9780128137611

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Advances in Heterocyclic Chemistry by Anonim Pdf

Advances in Heterocyclic Chemistry, Volume 124, is the definitive series in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Updates in this new volume include sections on the Organometallic Complexes of Azines, The Literature of Heterocyclic Chemistry, Part XV, Heterocycles Incorporating a Pentacoordinated, Hypervalent Phosphorus Atom, and Tautomerism and the Structure of Azoles: NMR Spectroscopy, amongst other related topics. Written by established authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Author : André B. Charette
Publisher : John Wiley & Sons
Page : 824 pages
File Size : 41,7 Mb
Release : 2015-07-15
Category : Science
ISBN : 9781118726570

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Handbook of Reagents for Organic Synthesis by André B. Charette Pdf

Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C–H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C–H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.