Cell Migration

Author : Ivana Pajic-Lijakovic,Elias Barriga
Publisher : Academic Press
Page : 316 pages
File Size : 53,7 Mb
Release : 2021-01-13
Category : Technology & Engineering
ISBN : 9780128203118

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Viscoelasticity and Collective Cell Migration by Ivana Pajic-Lijakovic,Elias Barriga Pdf

Viscoelasticity and Collective Cell Migration: An Interdisciplinary Perspective Across Levels of Organization focuses on the main viscoelastic parameters formulated based on multiscale constitutive modeling and how to measure these rheological parameters based on existent micro-devices such as micro-rheology and micro-elastography. The book sheds light on inter-relationships across viscoelasticity scales, an essential step for understanding various biomedical processes such as morphogenesis, wound healing and cancers invasion. Cumulative effects of structural changes at subcellular and cellular levels influence viscoelasticity at a supracellular level are also covered, providing valuable insights for biologists, physicists, engineers, students and researchers in the field of developmental biology. As this is a complex multidisciplinary field, perspectives are included from experts in biology, biochemistry, biomedicine, biophysics and biorheology. Readers will gain a deeper understanding of the complex dynamics that represent challenges and the necessity for further development in the field. Discusses the biological/biochemical mechanisms of collective cell migration Covers the inter-relation between collective cell migration and viscoelasticity by proposing rheological parameters Contains critical consideration of various experimental techniques that are suitable to measure these parameters

Author : Doris Wedlich
Publisher : John Wiley & Sons
Page : 398 pages
File Size : 48,5 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527604074

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Cell Migration in Development and Disease by Doris Wedlich Pdf

Cell Migration matches nearly all research areas in cell and developmental biology, genetics, and biomedicine. The field shows radical progress powered by the combination of new genomic tools, cell labeling techniques and the incorporation of new model systems. This is the first book to comprehensively cover cell migration from the identification of molecular mechanisms to the understanding of certain pathological disorders and cancer development.

Author : Jun-Lin Guan
Publisher : Springer Science & Business Media
Page : 359 pages
File Size : 51,8 Mb
Release : 2008-02-02
Category : Science
ISBN : 9781592598601

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Cell Migration by Jun-Lin Guan Pdf

A collection of classic, novel, and state-of-the-art methods for the study of cell migration in cultured cells, different model organisms, and specialized cells in normal development and disease. Highlights include basic assays that apply to all cell migration studies in vitro, assays in various model organisms, and assays for cancer cells, endothelial cells, and neurons both in vitro and in animal models. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Author : Frank Entschladen,Kurt S. Zänker
Publisher : Karger Medical and Scientific Publishers
Page : 185 pages
File Size : 53,5 Mb
Release : 2010
Category : Science
ISBN : 9783805593212

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Cell Migration by Frank Entschladen,Kurt S. Zänker Pdf

Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell's 'migrosome'.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease.

Author : Alexis Gautreau
Publisher : Springer Nature
Page : 402 pages
File Size : 47,6 Mb
Release : 2018-03-10
Category : Science
ISBN : 9781493977017

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Cell Migration by Alexis Gautreau Pdf

This volume covers various assays and techniques that have been developed to study and characterize the cell migration in vitro, ex vivo, and in vivo. The chapters in this book present readers with the latest protocols to observe, quantify, and control cell migration. Some of the topics explored in this book are: migration in confined environments, microfluidic devices, optogenetics, chemotaxis, electrotaxis, detection of migrasomes, migration of Q cells in Caenorhabditis elegans, of Drosophila macrophages, optogenetics of cell migration, intravital imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and comprehensive, Cell Migration: Methods and Protocols is a valuable resource for anyone interested in learning more about this expanding field.

Author : Caterina A. M. La Porta,Stefano Zapperi
Publisher : Springer Nature
Page : 135 pages
File Size : 52,8 Mb
Release : 2019-10-14
Category : Science
ISBN : 9783030175931

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Cell Migrations: Causes and Functions by Caterina A. M. La Porta,Stefano Zapperi Pdf

Cell migration plays an important role during development and in many physiological and pathological processes, from wound healing to cancer. This edited volume presents a collection of contributions meant to illustrate the state of the art on this topic from an interdisciplinary perspective. Readers will find a detailed discussion of the properties of individual and collective cell migration, including the associated biochemical regulation and important biophysical and biomechanical aspects. The book includes information on the latest experimental techniques employed to study cell migration, from microfluidics to traction force microscopy, as well as the latest theoretical and computational models used to interpret the experimental data. Finally, the role of cell migration in cancer and in development is also reviewed. The contents of this work should appeal to students and researchers in biology and biophysics who want to get up to date on the latest interdisciplinary development in this broad field of research. The chapters are written in a self-contained form and can also be used as individual articles.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 55,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Wedlich
Publisher : Unknown
Page : 398 pages
File Size : 41,8 Mb
Release : 2015-03-06
Category : Electronic
ISBN : 3527336982

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Cell Migration in Development and Disease by Wedlich Pdf

Author : Ajaykumar Vishwakarma,Jeffrey M Karp
Publisher : Academic Press
Page : 642 pages
File Size : 43,7 Mb
Release : 2017-03-22
Category : Science
ISBN : 9780128027561

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Biology and Engineering of Stem Cell Niches by Ajaykumar Vishwakarma,Jeffrey M Karp Pdf

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type. Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system Authored and edited by authorities in this emerging and multidisciplinary field Includes valuable links to 5-10 minute YouTube© author videos that describe main points

Author : Coert Margadant
Publisher : Springer Nature
Page : 468 pages
File Size : 50,6 Mb
Release : 2023-01-18
Category : Science
ISBN : 9781071628874

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Cell Migration in Three Dimensions by Coert Margadant Pdf

This detailed collection serves as a unique and excellent collection of state-of-the-art methods and protocols to interrogate cell migration in a wide variety of different contexts and model organisms, as well as advanced image analysis and quantitative assessment of a diverse array of parameters related to cell migration. The book focuses on the cell biology of cell migration, developmental model systems to assess cell migration during morphogenesis, cell migration in cancers and the tumor micro-environment, as well as blood vessel formation and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell Migration in Three Dimensions provides a solid foundation for scientists of different disciplines to investigate cell migration in biological processes. Chapters 7, 12, 16, 17, 19, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : Hélène D. Moreau,Jörg Renkawitz,Emmanuel Donnadieu
Publisher : Frontiers Media SA
Page : 178 pages
File Size : 46,9 Mb
Release : 2022-05-04
Category : Medical
ISBN : 9782889760886

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Immune Cell Migration in Health and Disease by Hélène D. Moreau,Jörg Renkawitz,Emmanuel Donnadieu Pdf

Author : Marie-Dominique Filippi,Hartmut Geiger
Publisher : Humana Press
Page : 326 pages
File Size : 49,8 Mb
Release : 2011-08-25
Category : Science
ISBN : 1617791466

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Stem Cell Migration by Marie-Dominique Filippi,Hartmut Geiger Pdf

The migration of stem cells has been found to be critical during early development for the organization of the embryonic body as well as during adult life with tissue homeostasis and regeneration of organ function. Due to the low frequency of these cells in vivo, problems in identifying and prospectively purifying tissue specific stem cells near homogeneity, and, most importantly, a lack of adequate technologies and protocols to study stem cell migration in vivo, this vital research has been quite difficult until recently. In Stem Cell Migration: Methods and Protocols, experts in the field compile and highlight the standard and novel techniques that allow the studying of the migration of stem cells in one succinct manual. Including protocols on germ, neuronal, and hematopoietic stem cells, during development and adulthood with a clear emphasis on in vivo technologies, the volume also extends its coverage to in vitro approaches toward several developmentally-conserved signaling pathways. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and convenient, Stem Cell Migration: Methods and Protocols provides key, state-of the art information on experimental techniques for studying stem cell migration both at a cellular and molecular level in development, regeneration, and disease.

Author : Takaaki Matsui,Mitsugu Fujita,Akihiko Ito
Publisher : Frontiers Media SA
Page : 122 pages
File Size : 45,8 Mb
Release : 2019-01-24
Category : Electronic
ISBN : 9782889456949

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Cell Adhesion and Migration in the Development of Multicellular Organisms by Takaaki Matsui,Mitsugu Fujita,Akihiko Ito Pdf

During development, cells are generated at specific locations within the embryo and then migrate into their destinations. At their destinations, they assemble together through cell adhesions, eventually leading to the formation of tissues and organs. In some cases, orchestration of cell adhesion and migration produces the global movement of cell groups, called collective cell migration, which is also required for the development of basic tissue structures such as spheres, clusters, and vesicles in the morphogenetic processes of development. Therefore, individual regulation and orchestration of cell adhesion and migration are quite important for appropriate tissue/organ formation during development. However, how cell adhesion and migration are regulated, and orchestrated during development? How cell adhesion and migration affects tissue formation during development? To answer these questions, we assembled several review and research articles in this eBook. By assembling these articles, we could explore the presence of core regulatory mechanisms and deepen the current understanding of cell adhesion and migration during the development of multicellular organisms.

Author : Jerome Delon,Manish Butte,Jens Volker Stein
Publisher : Frontiers Media SA
Page : 140 pages
File Size : 48,5 Mb
Release : 2022-11-16
Category : Medical
ISBN : 9782832506257

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The Cytoskeleton in T Cell Migration and Activation by Jerome Delon,Manish Butte,Jens Volker Stein Pdf

Author : Jonathan M. Lee
Publisher : Biota Publishing
Page : 82 pages
File Size : 47,5 Mb
Release : 2013-06-01
Category : Science
ISBN : 9781615043897

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The Actin Cytoskeleton and the Regulation of Cell Migration by Jonathan M. Lee Pdf

The mammalian cytoskeleton is an internal framework of actin, tubulin, and intermediate filament proteins. Proteins of these three classes assemble non-covalently into filamentous polymers that support the structural integrity of the relatively fragile lipid plasma membrane. In addition, cytoskeletal polymers provide the mechanical strength that hold a cell together and anchor it to its growth substrate. The cytoskeleton must also have the capacity for rapid and substantial remodeling and provide the motive and tractor force necessary to drive motility. As such, the cytoskeleton has a functional duality: sufficiently rigid to prevent plasma membrane deformation but pliable enough to allow for cytokinesis; sufficiently adhesive to allow for traction but dynamic enough to allow movement from one place to another. A major research challenge in cytoskeleton biology is to understand how cytoskeletal proteins assemble and dissemble in support of physiological processes. This chapter will focus on the role of the actin cytoskeleton in cell migration. More specifically, we will focus on the actin cytoskeleton of vertebrate cells. Table of Contents: Introduction / The Fundamentals of Actin Polymerization / Accessory Proteins Regulate Actin Polymerization and Assembly / Cellular Actin Structure / Cell Migration / Summary of Cell Migration / References / Author Biography