Cell Surface Engineering

Author : Mitsuyoshi Ueda
Publisher : Springer
Page : 185 pages
File Size : 40,5 Mb
Release : 2019-04-23
Category : Medical
ISBN : 9789811358685

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Yeast Cell Surface Engineering by Mitsuyoshi Ueda Pdf

This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.

Author : Rawil Fakhrullin,Insung Choi
Publisher : Royal Society of Chemistry
Page : 266 pages
File Size : 51,7 Mb
Release : 2014-07-24
Category : Medical
ISBN : 9781849739023

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Cell Surface Engineering by Rawil Fakhrullin,Insung Choi Pdf

A summary of the recent achievements in surface-functionalised cells including fabrication, characterisation, applications and nanotoxicity.

Author : Jeffrey M Karp,Weian Zhao
Publisher : William Andrew
Page : 395 pages
File Size : 49,5 Mb
Release : 2014-05-30
Category : Science
ISBN : 9781455731558

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Micro- and Nanoengineering of the Cell Surface by Jeffrey M Karp,Weian Zhao Pdf

Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis. The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas. Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics

Author : Rawil F Fakhrullin,Insung Choi,Yuri Lvov
Publisher : Royal Society of Chemistry
Page : 266 pages
File Size : 45,9 Mb
Release : 2014-07-08
Category : Technology & Engineering
ISBN : 9781782628477

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Cell Surface Engineering by Rawil F Fakhrullin,Insung Choi,Yuri Lvov Pdf

Cell surface engineering is an emerging field concerning cell surface modifications to enhance its functionalities. The book introduces the reader to the area of surface-functionalized cells and summarizes recent developments in the area including fabrication, characterization, applications and nanotoxicity. Topics covered include recent approaches for the functionalization of cells with nanomaterials (polymer nanofilms and nanoparticles), fabrication of functional biomimetic devices and assemblies based on nanoparticle-modified microbial cells and artificial spores (the bioinspired encapsulation of living cells with inorganic nanoshells). The book provides an interdisciplinary approach to the topic with authors from both biological and chemical backgrounds. This multidisciplinary view makes the book suitable for those interested in biomaterials, biochemistry, microbiology and colloid chemistry, providing both an introduction for postgraduate students as well as a comprehensive summary for those already working in the area. biomaterials, biochemistry, microbiology and colloid chemistry.

Author : Anil Mahapatro,Ankur S. Kulshrestha
Publisher : American Chemical Society
Page : 442 pages
File Size : 47,8 Mb
Release : 2008-04-17
Category : Science
ISBN : UOM:39015075620875

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Polymers for Biomedical Applications by Anil Mahapatro,Ankur S. Kulshrestha Pdf

Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.

Author : Huimin Zhao
Publisher : John Wiley & Sons
Page : 41 pages
File Size : 42,6 Mb
Release : 2021-08-23
Category : Science
ISBN : 9783527344703

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Protein Engineering by Huimin Zhao Pdf

A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.

Author : Katsunori Tanaka,Kenward Vong
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 44,6 Mb
Release : 2020-04-27
Category : Science
ISBN : 9783527344321

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Handbook of In Vivo Chemistry in Mice by Katsunori Tanaka,Kenward Vong Pdf

Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.

Author : Michael R. King
Publisher : Elsevier
Page : 339 pages
File Size : 48,7 Mb
Release : 2011-04-28
Category : Science
ISBN : 9780080539638

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Principles of Cellular Engineering by Michael R. King Pdf

This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine. -Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications -Useful to researchers in biomaterials, inflammation, and vascular biology -Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses

Author : Salvatore V. Pizzo
Publisher : Academic Press
Page : 144 pages
File Size : 44,5 Mb
Release : 2018-03-20
Category : Science
ISBN : 9780128123522

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Cell Surface GRP78, a New Paradigm in Signal Transduction Biology by Salvatore V. Pizzo Pdf

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative

Author : Springer
Publisher : Unknown
Page : 356 pages
File Size : 53,7 Mb
Release : 2012-04-24
Category : Electronic
ISBN : 3642282830

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Tissue Engineering III by Springer Pdf

Author : Zhou Nie
Publisher : John Wiley & Sons
Page : 549 pages
File Size : 51,5 Mb
Release : 2024-02-13
Category : Science
ISBN : 9783527840809

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DNA Nanotechnology for Cell Research by Zhou Nie Pdf

DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery. The text is divided into four parts. Part I surveys the progress of functional DNA nanotechnology tools for cellular recognition. Part II illustrates the use of DNA-based biochemical sensors to monitor and image intracellular molecules and processes. Part III examines the use of DNA to regulate biological functions of individual cells. Part IV elucidates the use of DNA nanotechnology for cell-targeted medical applications. Sample topics covered in DNA Nanotechnology for Cell Research include: Selections and applications of functional nucleic acid toolkits, including DNA/RNA aptamers, DNAzymes, and riboswitches, for cellular recognition, metabolite detection, and liquid biopsy. Developing intelligent DNA nanodevices implemented in living cells for amplified cell imaging, smart intracellular sensing, and in cellulo programmable biocomputing. Harnessing dynamic DNA nanotechnology for non-genetic cell membrane engineering, receptor signaling reprogramming, and cellular behavior regulation. Construction of biocompatible nucleic acid nanostructures as precisely controlled vehicles for drug delivery, immunotherapy, and tissue engineering. Providing an up-to-date tutorial style overview along with a highly valuable in-depth perspective, DNA Nanotechnology for Cell Research is an essential resource for the entire DNA-based nanotechnology community, including analytical chemists, biochemists, materials scientists, and bioengineers.

Author : Jonathan R. Lawrence,David Waugh
Publisher : Elsevier
Page : 719 pages
File Size : 53,6 Mb
Release : 2014-10-02
Category : Technology & Engineering
ISBN : 9781782420798

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Laser Surface Engineering by Jonathan R. Lawrence,David Waugh Pdf

Lasers can alter the surface composition and properties of materials in a highly controllable way, which makes them efficient and cost-effective tools for surface engineering. This book provides an overview of the different techniques, the laser-material interactions and the advantages and disadvantages for different applications. Part one looks at laser heat treatment, part two covers laser additive manufacturing such as laser-enhanced electroplating, and part three discusses laser micromachining, structuring and surface modification. Chemical and biological applications of laser surface engineering are explored in part four, including ways to improve the surface corrosion properties of metals. Provides an overview of thermal surface treatments using lasers, including the treatment of steels, light metal alloys, polycrystalline silicon and technical ceramics Addresses the development of new metallic materials, innovations in laser cladding and direct metal deposition, and the fabrication of tuneable micro- and nano-scale surface structures Chapters also cover laser structuring, surface modification, and the chemical and biological applications of laser surface engineering

Author : Vuk Uskokovic
Publisher : Elsevier
Page : 616 pages
File Size : 54,5 Mb
Release : 2017-11-22
Category : Medical
ISBN : 9780323480642

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Nanotechnologies in Preventive and Regenerative Medicine by Vuk Uskokovic Pdf

Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Author : R.S. Walia,Qasim Murtaza,Shailesh Mani Pandey,Ankit Tyagi
Publisher : CRC Press
Page : 325 pages
File Size : 48,7 Mb
Release : 2022-12-19
Category : Technology & Engineering
ISBN : 9781000798661

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Surface Engineering by R.S. Walia,Qasim Murtaza,Shailesh Mani Pandey,Ankit Tyagi Pdf

Surface engineering is considered an important aspect in the reduction of friction and wear. This reference text discusses a wide range of surface engineering technologies along with applications in a comprehensive manner. The book describes various methods in surface engineering technology with a thorough explanation of various aspects of each process that comes under this domain. Apart from an enhanced explanation of the process and its attributes, this book also gives insight into the types of materials, applications, and optimization of surface engineering techniques. It discusses important topics including surface engineering of the functionality of graded materials, materials characterization, processing of biomaterials, design, surface modification technologies and process control, smart manufacturing, artificial intelligence, and machine learning applications. The book: discusses computational and simulation analyses for better selection of process parameters covers optimizations of processes with state-of-the-art technologies discusses applications of surface engineering in medical, agricultural, architecture engineering, and allied sectors covers processing techniques of biomaterials in surface engineering The text is useful for senior undergraduate, graduate students, and academic researchers working in diverse areas such as industrial and production engineering, mechanical engineering, materials science, and manufacturing science. It covers a hybrid process for surface modification, modeling techniques, and issues in surface engineering.

Author : Alain Carré,Kash L. Mittal
Publisher : CRC Press
Page : 545 pages
File Size : 40,7 Mb
Release : 2011-01-19
Category : Science
ISBN : 9789004190788

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Surface and Interfacial Aspects of Cell Adhesion by Alain Carré,Kash L. Mittal Pdf

Cell adhesion comes into play in almost all domains of life. The range of situations in which it occurs, involving organisms, living tissues, microorganisms or single cells, is endless. Cell adhesion is involved in the binding of a cell to a surface, extracellular matrix, or another cell using cell adhesion molecules. It is crucial in the formation and maintenance of coherent multicellular structures. Cell surface adhesion molecules (integrins, for example) which transmit information from the extracellular matrix to the cell play vital roles in numerous cellular processes. Some of these include: cell growth, differentiation, embryogenesis, immune cell transmigration and response, and cancer metastasis. Also cell adhesion is involved in most of pathological situations. This book is divided into four parts as follows: Part 1: Fundamentals of Cell Adhesion; Part 2: Methods to Study Cell Adhesion; Part 3: Surface Treatments to Control Cell Adhesion and Behavior; and Part 4: Cell Adhesion in Medicine and Therapy. A bountiful information is covered in this book which represents the cumulative wisdom of many world-renowned researchers( physicists, materials scientists, chemists and biologists) engaged in unraveling the mechanisms of cell adhesion and how to mitigate or control it. It quite patent from the topics covered in this book that the subject of cell adhesion is truly interdisciplinary. This book should be of great interest and value to anyone interested in cell adhesion which is vitally important to human life.