Cellular And Molecular Effects Of Mineral And Synthetic Dusts And Fibres

Author : John M.G. Davis,Marie-Claude Jaurand
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 51,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642790416

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Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres by John M.G. Davis,Marie-Claude Jaurand Pdf

Presented here are recent data on the mechanisms of action of different dusts and fibres of industrial interest. Emphasis is placed on the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occurring after their interaction with fibrous and non-fibrous particulates including metal compounds. In four sections, the volume provides research findings in the following areas: - Cellular and Metabolic Changes Caused by Mineral Dusts - Molecular Changes and DNA Alterations Produced by Mineral Dusts - In Vivo Dust-Related Pathological Processes. Correlations Between in Vitro and in Vivo Data - Physico-Chemical Properties of Minerals in Relation to Their Biological Effects.

Author : Peter Gehr,Joachim Heyder
Publisher : CRC Press
Page : 718 pages
File Size : 40,9 Mb
Release : 2000-02-18
Category : Medical
ISBN : 9780824746896

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Particle-Lung Interactions by Peter Gehr,Joachim Heyder Pdf

This wide-ranging, comprehensive reference presents the latest developments in aerosol science and interactions between particles and the respiratory tract-utilizing an inter-disciplinary approach that integrates advances in physics, chemistry, and engineering with the epidemiological and biomedical sciences, and focusing on the dynamics of particl

Author : Eugene Papirer
Publisher : CRC Press
Page : 774 pages
File Size : 45,7 Mb
Release : 2000-04-05
Category : Science
ISBN : 9781482269703

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Adsorption on Silica Surfaces by Eugene Papirer Pdf

"Progresses from theoretical issues to applications. Contains a historical overview, in-depth considerations of various scenarios of silica adsorption, and results from the latest research. Invaluable for broad coverage of the expanding field of silica research."

Author : Anonim
Publisher : Unknown
Page : 1724 pages
File Size : 41,9 Mb
Release : 2000
Category : Environmental health
ISBN : RUTGERS:39030033070899

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Environmental Health Perspectives by Anonim Pdf

Author : Anonim
Publisher : Elsevier
Page : 246 pages
File Size : 46,6 Mb
Release : 2009-08-12
Category : Science
ISBN : 9780080886268

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Advances in Molecular Toxicology by Anonim Pdf

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed. Cutting-edge reviews by leading workers in the discipline In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine

Author : Nancy A. Monteiro-Riviere,C. Lang Tran
Publisher : CRC Press
Page : 452 pages
File Size : 49,6 Mb
Release : 2007-07-25
Category : Medical
ISBN : 9781420045154

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Nanotoxicology by Nancy A. Monteiro-Riviere,C. Lang Tran Pdf

Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are n

Author : Corrado L. Galli,Marina Marinovich,Alan M. Goldberg
Publisher : Springer Science & Business Media
Page : 378 pages
File Size : 50,9 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9783642798726

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Modulation of Cellular Responses in Toxicity by Corrado L. Galli,Marina Marinovich,Alan M. Goldberg Pdf

Proceedings of the NATO Advanced Study Institute on the Modulation of Cellular Response in Toxicity, held in Ponte di Legno, Italy , January 24 - February 3, 1994.

Author : P.J. Bert Hakkinen,Gerald Kennedy,Frederick W. Stoss
Publisher : Elsevier
Page : 953 pages
File Size : 40,7 Mb
Release : 2000-01-10
Category : Medical
ISBN : 9780080534664

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Information Resources in Toxicology by P.J. Bert Hakkinen,Gerald Kennedy,Frederick W. Stoss Pdf

Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Author : Fiorella Lo Schiavo,Robert L. Last,Giorgio Morelli,Natasha V. Raikhel
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 47,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642721175

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Cellular Integration of Signalling Pathways in Plant Development by Fiorella Lo Schiavo,Robert L. Last,Giorgio Morelli,Natasha V. Raikhel Pdf

In the last few years there have been tremendous advances in the understanding of signals and signalling pathways that operate at the cellular level and lead to developmental processes. In 27 chapters, this volume investigates the cellular and molecular basis of plant development. It highlights the most recent progress on signals, machinery, and pathways in the plant cell. Emphasis is placed on integrating these studies with those on cell division, cell plate formation, and other aspects of plant development, in order to elucidate the intricate relationships between them.

Author : Emel Arinc,John B. Schenkman,Ernest Hodgson
Publisher : Springer Science & Business Media
Page : 615 pages
File Size : 49,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642795282

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Molecular Aspects of Oxidative Drug Metabolizing Enzymes by Emel Arinc,John B. Schenkman,Ernest Hodgson Pdf

Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Springer Science & Business Media
Page : 580 pages
File Size : 40,6 Mb
Release : 2001-08-10
Category : Medical
ISBN : 9781592591251

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The Molecular Basis of Human Cancer by William B. Coleman,Gregory J. Tsongalis Pdf

Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.

Author : Axel R. Zander,Wolfram Ostertag,Boris V. Afanasiev,Frank Grosveld
Publisher : Springer Science & Business Media
Page : 534 pages
File Size : 40,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642611223

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Gene Technology by Axel R. Zander,Wolfram Ostertag,Boris V. Afanasiev,Frank Grosveld Pdf

The 11 th meeting in "Modern Trends in Human Leukemia" took place from June 19 to 21, 1994 in Wilsede in the middle of the Liineburger Heide, South of Hamburg. Interwoven with the Leukemia program was the Nato-sponsored Symposium of the ASI-Series "Gene Technology in Analysis of Malignant and Inherited Human Diseases Related to Development" . The Wilsede meeting was continued on a ship of the Neva leading through lake Ladoga and lake Onega. The topics of both meetings included discussion on recent progress isolation and development of hematopoietic stem cells, genes crucial for development and diseases, methods of gene transfer, application of gene transfer; oncogenes and anti-oncogenes as targets for gene therapy; receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukemias and bone marrow transplantation. The Nato workshop concentrated not only on analysis of cell systems useful for somatic gene therapy, but also on actual themes directly related to correction of human diseases. The latter aspects emphasized themes related to biotechnology, the first part was by nature more general. We also included a few contributions that discussed perspectives for the future of gene therapy and possible relationships to evolution.

Author : Maria C. Pedroso De Lima,Nejat Düzgünes,Dick Hoekstra
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 52,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642795473

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Trafficking of Intracellular Membranes: by Maria C. Pedroso De Lima,Nejat Düzgünes,Dick Hoekstra Pdf

This volume contains the lectures presented at the NATO Advanced Study Institute (ASI) on "Trafficking of Intracellular Membranes: From Molecular Sorting to Membrane Fusion", held in Espinho, Portugal, from June 19 to June 30,1994. The objective of this Institute was to survey recent developments and to discuss future directions in the rapidly advancing field of membrane cell biology, with particular emphasis on the dynamical properties and intracellular flow of membranes. A wide range of interrelated topics around the central theme of intracellular trafficking of membranes was covered, including lipid flow, membrane fusion, dynamics of membrane components, protein folding and assembly, vesicular transport in membrane biogenesis, exocytosis and endocytosis. A large variety of experimental techniques and systems, including the application of viruses and model systems, to study these processes was also considered. Membrane cell biology is a broad discipline which encompasses many scientific areas including cell biology, biochemistry, biophysics, virology, immunonology and genetics. Indeed, recent advances in the cell biology of membranes could not have been made without this multidisciplinary approach. Significant progress achieved during the last few years in understanding how newly synthesized lipids and proteins find their way to the cell organelles, how molecular sorting and the continuous flow of membranes allow each cellular membrane to maintain its own distinct molecular composition, and, thereby, the individuality of the various intracellular compartments, was discussed in considerable detail in this Institute.

Author : T.Faruk Bozoglu,Bibek Ray
Publisher : Springer Science & Business Media
Page : 407 pages
File Size : 49,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642614620

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Lactic Acid Bacteria by T.Faruk Bozoglu,Bibek Ray Pdf

For a long time, lactic acid bacteria have played an indispensable role in food production. This book provides an overview and recent findings on their genetics and biochemistry as well as possible applications. The development and use of non-pathogenic lactic acid bacteria in vaccine delivery systems for mucosal immunizations are discussed. Their role in food fermentation, their use in carbohydrate modification and key systems for proteolysis and lantibiotic production are treated in detail. Further, the transformation of organic wastes into food and fertilizers is covered. The volume contains a wealth of useful information and can serve both as an introduction to the field for beginners and as a reference book.

Author : Alain Jaquemin-Sablon
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 42,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642611155

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Flow and Image Cytometry by Alain Jaquemin-Sablon Pdf

Image analysis and flow cytometry are complementary techniques which provide new insights into essential aspects of cell biology. This book presents an up-to-date overview of current ideas and methods in these domains. It consists of three parts. Part I, "Membrane Dynamics and Function", deals with adhesion molecules, membrane pump dynamics, membrane fusion and endocytosis, membrane potential, T-cell homing and cytoskeleton, etc. The second part focuses on problems of cell proliferation, chromosome analysis and sorting, apoptosis, imaging cytometry of fixed and living cells, image analysis for gene mapping from flow-sorted chromosomes, chromatin organization, and liposome-mediated delivery of DNA binding drugs. The third part covers data management systems, cell sorting techniques and microscopy.