Cerebrospinal Fluid

Author : Florian Deisenhammer,Finn Sellebjerg,Charlotte E Teunissen,Hayrettin Tumani
Publisher : Springer
Page : 441 pages
File Size : 53,8 Mb
Release : 2015-02-05
Category : Medical
ISBN : 9783319012254

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Cerebrospinal Fluid in Clinical Neurology by Florian Deisenhammer,Finn Sellebjerg,Charlotte E Teunissen,Hayrettin Tumani Pdf

The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.

Author : Robert M. Herndon,Roger A. Brumback
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 51,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461315919

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The Cerebrospinal Fluid by Robert M. Herndon,Roger A. Brumback Pdf

For centuries the great minds of medical science puzzled over the importance of the cerebrospinal fluid. As far back as Hippocrates, it was thought that this "phlegm" that flooded the intracranial contents had pathological significance. However, not until the late 1800s, when Quincke introduced and popularized lumbar puncture, did physicians take an interest in the study of this fluid in relation to clinical illness. Since then a variety of techniques for obtaining cerebrospinal fluid from various sites have developed, and the relationship of cerebrospinal fluid to a variety of disease processes has received considerable study. In this volume, we have attempted to assemble reviews of some of these important developments during the past century. Chapter 1 contains a historical review of key investigations that helped shape our concepts of cerebrospinal fluid from the earliest recorded description by the author of the Edwin Smith Surgical Papyrus in the seventeenth century B. C. to contemporaries such as Kabat, Glusman, and Knaub, who introduced quantitative determinations of cerebrospinal fluid gamma globulin levels. In Chapter 2 there is a description of our current understanding of the anatomical compartment for the cerebrospinal fluid and the physiology of its formation, circulation, and absorption. Dr. Richard Leech in Chapter 3 contributes a comprehensive description of the disorders associated with excessive quanti ties of cerebrospinal fluid-commonly referred to as hydrocephalus. A variety of techniques for properly collecting and evaluating cerebrospinal fluid are detailed in Chapter 4.

Author : Wei Zheng,Adam Chodobski
Publisher : CRC Press
Page : 668 pages
File Size : 43,9 Mb
Release : 2005-03-30
Category : Medical
ISBN : 1420023403

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The Blood-Cerebrospinal Fluid Barrier by Wei Zheng,Adam Chodobski Pdf

Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.

Author : Robert A. Fishman
Publisher : Unknown
Page : 456 pages
File Size : 40,7 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015025299317

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Cerebrospinal Fluid in Diseases of the Nervous System by Robert A. Fishman Pdf

This comprehensive and authoritative text covers the anatomical and physiological aspects of cerebrospinal fluid. Also includes material on differential diagnosis, AIDS, neuro-oncology, psychiatric disorders, and the composition and clinical examination of cerebrospinal fluid, including a detailed discussion on the treatment of complications of the lumbar puncture.

Author : David N. Irani
Publisher : Elsevier Health Sciences
Page : 329 pages
File Size : 42,9 Mb
Release : 2008-10-30
Category : Medical
ISBN : 9781416029083

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Cerebrospinal Fluid in Clinical Practice by David N. Irani Pdf

Given the evolution of cerebrospinal testing (CSF) testing methods, the near future is certain to see an explosion of new CSF analysis methodologies. Broad-based and extensively illustrated, Cerebrospinal Fluid in Clinical Practice provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. It examines the alterations of the composition of CSF in relation to diseases and disorders of the nervous system, emphasizing the findings that are useful in clinical practice. This expansive reference is perfect regardless of your level of experience in central nervous system diseases. Provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. Explores the gamut of all CNS infections for a broad but detailed review of the scope of neurological disease. Contains detailed discussion on the proper use of specific diagnostic screens on CSF, so you may gain knowledge on how new diagnostic methods impact clinical medicine. Incorporates extensive illustrations and tables, with visual emphasis on diagnostic, laboratory, and anatomic data.

Author : Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Publisher : Butterworth-Heinemann
Page : 1128 pages
File Size : 46,6 Mb
Release : 1990
Category : Medical
ISBN : MINN:31951D00416688Z

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Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

Author : James H. Wood
Publisher : Springer Science & Business Media
Page : 771 pages
File Size : 48,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781468410396

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Neurobiology of Cerebrospinal Fluid 1 by James H. Wood Pdf

Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu lation and in elimination of possible sources of error.

Author : Bora Gürer,Pinar Kuru Bektaşoğlu
Publisher : BoD – Books on Demand
Page : 184 pages
File Size : 43,5 Mb
Release : 2022-01-19
Category : Medical
ISBN : 9781839696954

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Cerebrospinal Fluid by Bora Gürer,Pinar Kuru Bektaşoğlu Pdf

Cerebrospinal fluid is an essential, clear, and colorless liquid essential for maintaining homeostasis of the brain and neuronal functioning. Its secretion in adults ranges from 400 to 600 ml per day and it is renewed about four or five times daily. Cerebrospinal fluid is mainly reabsorbed from arachnoid granulations. Any disruption in this well-regulated system, such as overproduction, decreased absorption, or obstruction, could lead to hydrocephalus. This book contains essential knowledge about cerebrospinal fluid anatomy and physiology, pathologies related to cerebrospinal fluid, and treatment strategies for cerebrospinal fluid disorders.

Author : G. Cinalli,W.J. Maixner,C. Sainte-Rose
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9788847021211

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Pediatric Hydrocephalus by G. Cinalli,W.J. Maixner,C. Sainte-Rose Pdf

In the last ten years the pediatric neurosurgeon has witnessed a real revolution in the diagnosis and treatment of pediatric hydrocephalus, the most frequently encountered condition in everyday clinical practice. The evolution of MRI and the advent of neuroendoscopic surgery have resuscitated the interest in the classification, etiology and pathophysiology of hydrocephalus. The book offers an updated overview on the recent progress in this field, and a new approach to hydrocephalus: the reader will find in it a modern and new presentation of an old disease, where genetics, endoscopy, cost-effectiveness analyses and many other aspects of the various therapies are extensively discussed. The volume will be useful not only for neurosurgeons, but for all specialists interested in the various aspects of hydrocephalus: pediatricians, radiologists, endocrinologists, pathologists and geneticists.

Author : Dan Greitz
Publisher : Unknown
Page : 23 pages
File Size : 41,6 Mb
Release : 1993
Category : Electronic
ISBN : 9162808567

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Cerebrospinal Fluid Circulation and Associated Intracranial Dynamics by Dan Greitz Pdf

Author : Conor Mallucci,Spyros Sgouros
Publisher : CRC Press
Page : 592 pages
File Size : 43,9 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420016284

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Cerebrospinal Fluid Disorders by Conor Mallucci,Spyros Sgouros Pdf

Addressing the gap in the literature between pediatric medicine and geriatric medicine, Cerebrospinal Fluid Disorders examines the disorders of the cerebrospinal fluid (CSF) pathways from birth to old age. Highlights of the book include:Comprehensive content detailing CSF disorders and their effects on the brain and spine at all developmental stage

Author : Abel Lajtha
Publisher : Springer
Page : 516 pages
File Size : 44,5 Mb
Release : 1982-12-01
Category : Science
ISBN : 0306409720

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Experimental Neurochemistry by Abel Lajtha Pdf

The second volume of the Handbook does not parallel any volume of the first edition; it is one more sign, or reflection, of the expansion of the field. By emphasizing the experimental approach, it illustrates the tools that have re cently become available for investigating the nervous system. Also, perhaps even more than other volumes, it illustrates the multidisciplinary nature of the field, requiring multidisciplinary methodology. It is now recognized that the availability of methodology is often the rate-limiting determinant of studies and that improvements or innovations in instrumentation can open up new avenues. A new improved method, although opening up new possibilities and being crucial to making advances, is only a tool whose use will determine its use fulness. If we do not recognize its possibilities, its use will be limited; if we do not recognize its limitations, it will mislead us. It is the possibilities and limitations and the results obtained that are illustrated here.

Author : Syed Z. Ali,Edmund S. Cibas
Publisher : Springer Science & Business Media
Page : 287 pages
File Size : 49,9 Mb
Release : 2012-03-08
Category : Medical
ISBN : 9781461417767

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Serous Cavity Fluid and Cerebrospinal Fluid Cytopathology by Syed Z. Ali,Edmund S. Cibas Pdf

Cytologic diagnosis by examination of exfoliated cells in serous cavity fluids is one of the most challenging areas in clinical cytopathology. Almost 20% of the effusions examined are directly or indirectly related to the presence of malignant disease, with carcinoma of the lung as the most common underlying culprit. This volume published in the Essentials in Cytopathology book series will fulfill the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket, ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format.

Author : Enrique Santamaría,Joaquín Fernández-Irigoyen
Publisher : Humana
Page : 557 pages
File Size : 40,9 Mb
Release : 2019-08-21
Category : Medical
ISBN : 149399705X

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Cerebrospinal Fluid (CSF) Proteomics by Enrique Santamaría,Joaquín Fernández-Irigoyen Pdf

This volume focuses on protein analysis, including a wide range of the use of mass spectrometry and other protein methods within neurobiological disciplines. Chapters cover topics such as cerebrospinal fluid (CSF) processing and biobanking; label-free quantitative proteomics; SWATH; top-down proteomics; and experimental strategies based on other –omics applied to CSF metabolome, lipidome, and microRNAome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols is a valuable resource for graduate students and post-doctoral fellows interested in learning more about CSF proteotyping. It is also useful to established researchers seeking further insight into this growing field.

Author : Anonim
Publisher : Elsevier
Page : 320 pages
File Size : 50,8 Mb
Release : 2017-12-01
Category : Medical
ISBN : 0128042796

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Cerebrospinal Fluid in Neurologic Disorders by Anonim Pdf

Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available