Cerebrospinal Fluid In Neurologic Disorders

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Cerebrospinal Fluid in Clinical Neurology

Florian Deisenhammer,Finn Sellebjerg,Charlotte E Teunissen,Hayrettin Tumani
Cerebrospinal Fluid in Clinical Neurology Book PDF

Author : Florian Deisenhammer,Finn Sellebjerg,Charlotte E Teunissen,Hayrettin Tumani
Publisher : Springer
Page : 441 pages
File Size : 40,7 Mb
Release : 2015-02-05
Category : Medical
ISBN : 9783319012254

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Cerebrospinal Fluid in Clinical Neurology by Florian Deisenhammer,Finn Sellebjerg,Charlotte E Teunissen,Hayrettin Tumani Pdf

The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.

Cerebrospinal Fluid in Neurologic Disorders

Anonim
Cerebrospinal Fluid in Neurologic Disorders Book PDF

Author : Anonim
Publisher : Elsevier
Page : 320 pages
File Size : 40,5 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9780128043240

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Cerebrospinal Fluid in Neurologic Disorders by Anonim Pdf

Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available

Cerebrospinal Fluid in Diseases of the Nervous System

Robert A. Fishman
Cerebrospinal Fluid in Diseases of the Nervous System Book PDF

Author : Robert A. Fishman
Publisher : Unknown
Page : 456 pages
File Size : 51,5 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015025299317

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Cerebrospinal Fluid in Diseases of the Nervous System by Robert A. Fishman Pdf

This comprehensive and authoritative text covers the anatomical and physiological aspects of cerebrospinal fluid. Also includes material on differential diagnosis, AIDS, neuro-oncology, psychiatric disorders, and the composition and clinical examination of cerebrospinal fluid, including a detailed discussion on the treatment of complications of the lumbar puncture.

Cerebrospinal Fluid in Neurology and Psychiatry

Joseph R. Bianchine,H. McConnell
Cerebrospinal Fluid in Neurology and Psychiatry Book PDF

Author : Joseph R. Bianchine,H. McConnell
Publisher : Springer
Page : 330 pages
File Size : 51,9 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489933720

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Cerebrospinal Fluid in Neurology and Psychiatry by Joseph R. Bianchine,H. McConnell Pdf

Scientists have speculated as to the nature of cerebrospinal fluid (CSF) - "the third circulation" or "vital spirit" for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an "animal spirit" directing all our activities, as thought by Galen (Singer, 1956) or but a "modified tap water" (Halliburton, 1917)? With the advent of lumbar puncture, cerebrospinal fluid has become a readily available and important means of studying disease affecting the nervous system. In recent years, many sophisticated tools including com puter guided gas chromatography/mass spectrometry and high performance liquid chromatography have made it possible to identify and quantify many constituents of this fluid. The CSF has an enormous, though largely "untapped", potential in aiding diagnosis and evaluating treatment of many neurological, psychiatric and systemic disorders. As the ependyma is only a diffusional barrier between the CSF and extracellular fluid of the brain for many compounds, changes in the concentration of these compounds in the CSF may reflect disease processes in the brain.

The Cerebrospinal Fluid

Robert M. Herndon,Roger A. Brumback
The Cerebrospinal Fluid Book PDF

Author : Robert M. Herndon,Roger A. Brumback
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461315919

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The Cerebrospinal Fluid by Robert M. Herndon,Roger A. Brumback Pdf

For centuries the great minds of medical science puzzled over the importance of the cerebrospinal fluid. As far back as Hippocrates, it was thought that this "phlegm" that flooded the intracranial contents had pathological significance. However, not until the late 1800s, when Quincke introduced and popularized lumbar puncture, did physicians take an interest in the study of this fluid in relation to clinical illness. Since then a variety of techniques for obtaining cerebrospinal fluid from various sites have developed, and the relationship of cerebrospinal fluid to a variety of disease processes has received considerable study. In this volume, we have attempted to assemble reviews of some of these important developments during the past century. Chapter 1 contains a historical review of key investigations that helped shape our concepts of cerebrospinal fluid from the earliest recorded description by the author of the Edwin Smith Surgical Papyrus in the seventeenth century B. C. to contemporaries such as Kabat, Glusman, and Knaub, who introduced quantitative determinations of cerebrospinal fluid gamma globulin levels. In Chapter 2 there is a description of our current understanding of the anatomical compartment for the cerebrospinal fluid and the physiology of its formation, circulation, and absorption. Dr. Richard Leech in Chapter 3 contributes a comprehensive description of the disorders associated with excessive quanti ties of cerebrospinal fluid-commonly referred to as hydrocephalus. A variety of techniques for properly collecting and evaluating cerebrospinal fluid are detailed in Chapter 4.

Cerebrospinal Fluid Disorders

David D. Limbrick Jr.,Jeffrey R. Leonard
Cerebrospinal Fluid Disorders Book PDF

Author : David D. Limbrick Jr.,Jeffrey R. Leonard
Publisher : Springer
Page : 387 pages
File Size : 41,6 Mb
Release : 2018-11-10
Category : Medical
ISBN : 9783319979281

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Cerebrospinal Fluid Disorders by David D. Limbrick Jr.,Jeffrey R. Leonard Pdf

Hydrocephalus is one of the most common diseases of pediatric and adult neurosurgery. With the introduction of modern neurosurgical procedures, this disease has become a life-long problem. Even with optimal treatment, there is still significant morbidity and mortality along with a significant cost to the medical system. This has caused patients and their families to demand improvements in treatments and forced clinicians to evaluate their treatments in large consortiums while utilizing both genetics and technology to improve outcomes or avoid placement of shunt all together. This text is designed to present the current treatments for hydrocephalus across the lifespan. The foundation for understanding cerebral spinal fluid (CSF) abnormalities begins with the understanding of physiology and pathogenesis of disease. These chapters are written by published experts in the field and detail the significant advances in the detection of CSF abnormalities. This section will discuss the current advances in imaging and current research in biomarkers for both pediatric and adult patients. We will then systematically discuss the treatment of both pediatric and adult CSF disorders. These will be broken down by cause, since the physiology of each can be different. We will end the book with a discussion both of the technological advances and a discussion of consortiums and how they have advanced treatment of this chronic disease.

Cerebrospinal Fluid

Vendelin Slavik,Tereza Dolezal
Cerebrospinal Fluid Book PDF

Author : Vendelin Slavik,Tereza Dolezal
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 40,8 Mb
Release : 2012
Category : Cerebrospinal fluid
ISBN : 1620810174

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Cerebrospinal Fluid by Vendelin Slavik,Tereza Dolezal Pdf

Cerebrospinal fluid (CSF) is a clear colourless fluid and the major part of the extracellular fluid of the central nervous system. The CSF fills the brain ventricles and central spinal canal and forms a thin layer around the brain and spinal cord in the subarachnoid space and cisterns. In this book, the authors present current research in the study of the functions, composition and disorders relating to the cerebrospinal fluid. Topics include the proteomics of cerebral microdialysate; neuronal cytoskeleton components in cerebrospinal fluid in selected neurological diseases; composition of normal and pathological cerebrospinal fluid in neuropathology; cerebrospinal fluid flow dynamics; and cerebrospinal fluid biomarkers for Alzheimer's disease.

Neurobiology of Cerebrospinal Fluid 1

James H. Wood
Neurobiology of Cerebrospinal Fluid 1 Book PDF

Author : James H. Wood
Publisher : Springer Science & Business Media
Page : 771 pages
File Size : 43,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781468410396

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Neurobiology of Cerebrospinal Fluid 1 by James H. Wood Pdf

Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu lation and in elimination of possible sources of error.

Cerebrospinal Fluid Disorders

Conor Mallucci,Spyros Sgouros
Cerebrospinal Fluid Disorders Book PDF

Author : Conor Mallucci,Spyros Sgouros
Publisher : CRC Press
Page : 592 pages
File Size : 47,8 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420016284

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Cerebrospinal Fluid Disorders by Conor Mallucci,Spyros Sgouros Pdf

Addressing the gap in the literature between pediatric medicine and geriatric medicine, Cerebrospinal Fluid Disorders examines the disorders of the cerebrospinal fluid (CSF) pathways from birth to old age. Highlights of the book include:Comprehensive content detailing CSF disorders and their effects on the brain and spine at all developmental stage

Neurobiology of Cerebrospinal Fluid 2

James H. Wood
Neurobiology of Cerebrospinal Fluid 2 Book PDF

Author : James H. Wood
Publisher : Springer Science & Business Media
Page : 969 pages
File Size : 50,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461592693

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Neurobiology of Cerebrospinal Fluid 2 by James H. Wood Pdf

Since the publication of Neurobiology of Cerebrospinal Fluid 1 in 1980, that text has become the definitive reference concerning cerebrospinal fluid (CSF) for both basic scientists and clinicians involved in the investigation of degenerative, convulsive, cerebrovascular, traumatic, immunological, demyelinating, inflammatory, neoplastic, neuroendocrine, and psychiatric disorders. That initial volume began a tradition of detailed topic reviews written by international authorities with first-hand expertise in their respective fields of CSF research. Neurobiology of Cerebrospinal Fluid 2 represents a hefty collection of extensively refer enced and illustrated chapters covering topics not discussed in Vol. 1. More specifically, these chapters contain ample charts of original data, summary charts, and anatomical diagrams. Detailed illustrations of experimental and clinical techniques have been in cluded to facilitate their practical application. Each chapter in this multidisciplinary text has been critically reviewed by two experts in the respective field, and the appropriate revisions have been made. Recently published references and text modifications have been added at the proof stage in an effort to provide the most up-to-date review chapters possible.

Cerebrospinal Fluid in Clinical Practice

David N. Irani
Cerebrospinal Fluid in Clinical Practice Book PDF

Author : David N. Irani
Publisher : Elsevier Health Sciences
Page : 329 pages
File Size : 53,7 Mb
Release : 2008-10-30
Category : Medical
ISBN : 9781416029083

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Cerebrospinal Fluid in Clinical Practice by David N. Irani Pdf

Given the evolution of cerebrospinal testing (CSF) testing methods, the near future is certain to see an explosion of new CSF analysis methodologies. Broad-based and extensively illustrated, Cerebrospinal Fluid in Clinical Practice provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. It examines the alterations of the composition of CSF in relation to diseases and disorders of the nervous system, emphasizing the findings that are useful in clinical practice. This expansive reference is perfect regardless of your level of experience in central nervous system diseases. Provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. Explores the gamut of all CNS infections for a broad but detailed review of the scope of neurological disease. Contains detailed discussion on the proper use of specific diagnostic screens on CSF, so you may gain knowledge on how new diagnostic methods impact clinical medicine. Incorporates extensive illustrations and tables, with visual emphasis on diagnostic, laboratory, and anatomic data.

Clinical Methods

Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Clinical Methods Book PDF

Author : Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Publisher : Butterworth-Heinemann
Page : 1128 pages
File Size : 41,8 Mb
Release : 1990
Category : Medical
ISBN : MINN:31951D00416688Z

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Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

Proteins of the Cerebrospinal Fluid

Edward J. Thompson
Proteins of the Cerebrospinal Fluid Book PDF

Author : Edward J. Thompson
Publisher : Elsevier
Page : 300 pages
File Size : 51,5 Mb
Release : 2005-07-14
Category : Science
ISBN : 0080460097

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Proteins of the Cerebrospinal Fluid by Edward J. Thompson Pdf

The analysis of the protein content of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including Multiple Sclerosis and Encephalitis. Proteins of the Cerebrospinal Fluid is a complete revision of the first edition published 16 years ago and reflects the advances in the field in that period. Containing the most comprehensive reference list available today with over 1300 references cross-indexed according to topics, it also includes many classical works that cannot be easily found through the public literature database (like PubMed). This book covers new areas of research such as the use of the analysis of protein content in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes). With many new or completely revised illustrations, this book serves as not only a reference on the topic, but also a lab manual for bench work with recipes, and a clinical reference on individual diseases. Introduces the Eastern blotting, the technique considered the "gold standard" by the US Food & Drug Administration (FDA) for the demonstration of IgG by immunofixation following isoelectric focusing Provides numerous tables for ease-of-use Extensively cross-referenced with over 1300 references

The Blood-Cerebrospinal Fluid Barrier

Wei Zheng,Adam Chodobski
The Blood Cerebrospinal Fluid Barrier Book PDF

Author : Wei Zheng,Adam Chodobski
Publisher : CRC Press
Page : 668 pages
File Size : 50,9 Mb
Release : 2005-03-30
Category : Medical
ISBN : 1420023403

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The Blood-Cerebrospinal Fluid Barrier by Wei Zheng,Adam Chodobski Pdf

Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.

Veterinary Cytology

Leslie C. Sharkey,M. Judith Radin,Davis M. Seelig
Veterinary Cytology Book PDF

Author : Leslie C. Sharkey,M. Judith Radin,Davis M. Seelig
Publisher : John Wiley & Sons
Page : 2168 pages
File Size : 41,5 Mb
Release : 2020-08-11
Category : Medical
ISBN : 9781119125716

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Veterinary Cytology by Leslie C. Sharkey,M. Judith Radin,Davis M. Seelig Pdf

This book offers a state-of-the-art, evidence-based reference to all aspects of veterinary cytology. Truly multidisciplinary in its approach, chapters are written by experts in fields ranging from clinical pathology to internal medicine, surgery, ophthalmology, and dermatology, drawing the various specialties together to create a comprehensive picture of cytology's role in diagnosis and treatment of animal disease. Firmly grounded in the primary literature, the book focuses on companion animals, with special chapters for species with fewer publications. Chapters are logically organized by body system, with additional chapters on tumors of particular import and diagnostic decision making. The first two sections of Veterinary Cytology focus on cytology techniques, quality control, and special laboratory techniques. Subsequent sections are organ/tissue-based and reflect what is known about the canine, feline, and equine species. This is followed by chapters on non-traditional species, including exotic companion mammals, rabbits, cattle, camelids, non-human primates, reptiles and birds, amphibians, fish, invertebrates, and sheep and goats. The last section highlights some unique features of the applications of cytology in industry settings. Provides a gold-standard reference to data-driven information about cytologic analysis in companion animal species Brings together authors from a wide range of specialties to present a thorough survey of cytology's use in veterinary medicine Offers broader species coverage and greater depth than any cytology reference currently available Veterinary Cytology is an essential resource for clinical and anatomic pathologists and any specialist in areas using cytology, including veterinary oncologists, criticalists, surgeons, ophthalmologists, dermatologists, and internists.