Chemistry Of Protein Conjugation And Cross Linking

Chemistry Of Protein Conjugation And Cross Linking Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Chemistry Of Protein Conjugation And Cross Linking book. This book definitely worth reading, it is an incredibly well-written.

Chemistry of Protein Conjugation and Cross-Linking

Shan S. Wong
Chemistry of Protein Conjugation and Cross Linking Book PDF

Author : Shan S. Wong
Publisher : CRC Press
Page : 360 pages
File Size : 44,5 Mb
Release : 1991-06-18
Category : Medical
ISBN : 0849358868

Get Book

Chemistry of Protein Conjugation and Cross-Linking by Shan S. Wong Pdf

Chemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition

Shan S. Wong,David M. Jameson
Chemistry of Protein and Nucleic Acid Cross Linking and Conjugation Second Edition Book PDF

Author : Shan S. Wong,David M. Jameson
Publisher : CRC Press
Page : 624 pages
File Size : 53,9 Mb
Release : 2011-10-10
Category : Medical
ISBN : 9780849374913

Get Book

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition by Shan S. Wong,David M. Jameson Pdf

Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivity and resolution have facilitated the analysis of cross-linked products. Updated to reflect the advances of the 21st century, this book offers: An overview of the chemical principles underlying the processes of cross-linking and conjugation A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations

Protein Crosslinking

Mendel Friedman
Protein Crosslinking Book PDF

Author : Mendel Friedman
Publisher : Springer Science & Business Media
Page : 765 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468432824

Get Book

Protein Crosslinking by Mendel Friedman Pdf

The word crosslinking implies durable combination of (usually large) distinct elements at specific places to create a new entity that has different properties as a result of the union. In the case of proteins, such crosslinking often results in important changes in chemical, functional, nutritional, and biomedical properties, besides physical properties simply related to molecular size and shape. (Nucleic acids, carbohydrates, and other biopolymers are correspondingly affected.) Since proteins are ubiquitous, the consequences of their crosslinking are widespread and often profound. Scientists from many disciplines including organic chemistry, bio chemistry, protein chemistry, food science, nutrition, radiation biology, pharmacology, physiology, medicine, and dentistry are, therefore, minutely interested in protein crosslinking reactions and their implications. Because protein crosslinking encompasses so many disciplines, in organizing the Symposium on Nutritional and Biochemical Conse quences of Protein Crosslinking sponsored by the Protein Subdivi sion of the Division of Agricultural and Food Chemistry of the American Chemical Society, I sought participants with the broadest possible range of interests, yet with a common concern for theore tical and practical aspects of protein crosslinking. An important function of a symposium is to catalyze progress by bringing together ideas and experiences needed for interaction among different, yet related disciplines. To my pleasant surprise, nearly everyone invited came to San Francisco to participate.

Bioconjugate Techniques

Greg T. Hermanson
Bioconjugate Techniques Book PDF

Author : Greg T. Hermanson
Publisher : Academic Press
Page : 1233 pages
File Size : 43,6 Mb
Release : 2010-07-26
Category : Science
ISBN : 9780080568720

Get Book

Bioconjugate Techniques by Greg T. Hermanson Pdf

Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions

Protein Crosslinking

Mendel Friedman
Protein Crosslinking Book PDF

Author : Mendel Friedman
Publisher : Springer Science & Business Media
Page : 744 pages
File Size : 49,8 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781475791136

Get Book

Protein Crosslinking by Mendel Friedman Pdf

The word crosslinking implies durable combination of usually large, distinct elements at specific places to create a new entity that has different properties as a result of the union. In the case of proteins, such crosslinking often results in important changes in chemical, physical, functional, nutritional, and biome dical properties, besides physical properties simply related to molecular size and shape. (Nucleic acids, carbohydrates~ glyco proteins, and other biopolymers are correspondingly affected.) Since proteins are ubiquitous, the consequences of their crosslin king are widespread and often profound. Scientists from many dis ciplines including organic chemistry, biochemistry, protein chemis try, food science, nutrition, radiation biology, pharmacology, physiology, medicine, and dentistry are, therefore, very much inte rested in protein crosslinking reactions and their implications. Because protein crosslinking encompasses so many disciplines, in organizing the Symposium on Nutritional and Biochemical Consequences of Protein Crosslinking sponsored by the Protein Subdivision of the Division of Agricultural and Food Chemistry of the American Chemical Society, I sought participants with the broadest possible range of interests, yet with a common concern for theoretical and practical aspects of protein crosslinking. An important function of a symposium is to catalyze progress by bringing together ideas and experiences needed for interaction among different, yet related disciplines. To my pleasant surprize, nearly everone invited came to San Francisco to participate.

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation

Shan S. Wong,David M. Jameson
Chemistry of Protein and Nucleic Acid Cross Linking and Conjugation Book PDF

Author : Shan S. Wong,David M. Jameson
Publisher : CRC Press
Page : 608 pages
File Size : 51,8 Mb
Release : 2011-10-10
Category : Medical
ISBN : 9781420007640

Get Book

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation by Shan S. Wong,David M. Jameson Pdf

Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross

Polymer Modification

Graham G. Swift,Charles E. Carraher Jr.,Chris Bowman
Polymer Modification Book PDF

Author : Graham G. Swift,Charles E. Carraher Jr.,Chris Bowman
Publisher : Springer Science & Business Media
Page : 207 pages
File Size : 52,7 Mb
Release : 2013-06-29
Category : Technology & Engineering
ISBN : 9781489914774

Get Book

Polymer Modification by Graham G. Swift,Charles E. Carraher Jr.,Chris Bowman Pdf

Proceedings of an ACS-PMSE Division Symposium held in Orlando, Florida, August 21-25, 1996

Protein Crosslinking

Mendel Friedman
Protein Crosslinking Book PDF

Author : Mendel Friedman
Publisher : Springer
Page : 760 pages
File Size : 49,9 Mb
Release : 1977-09-01
Category : Science
ISBN : 0306390876

Get Book

Protein Crosslinking by Mendel Friedman Pdf

The word crosslinking implies durable combination of (usually large) distinct elements at specific places to create a new entity that has different properties as a result of the union. In the case of proteins, such crosslinking often results in important changes in chemical, functional, nutritional, and biomedical properties, besides physical properties simply related to molecular size and shape. (Nucleic acids, carbohydrates, and other biopolymers are correspondingly affected.) Since proteins are ubiquitous, the consequences of their crosslinking are widespread and often profound. Scientists from many disciplines including organic chemistry, bio chemistry, protein chemistry, food science, nutrition, radiation biology, pharmacology, physiology, medicine, and dentistry are, therefore, minutely interested in protein crosslinking reactions and their implications. Because protein crosslinking encompasses so many disciplines, in organizing the Symposium on Nutritional and Biochemical Conse quences of Protein Crosslinking sponsored by the Protein Subdivi sion of the Division of Agricultural and Food Chemistry of the American Chemical Society, I sought participants with the broadest possible range of interests, yet with a common concern for theore tical and practical aspects of protein crosslinking. An important function of a symposium is to catalyze progress by bringing together ideas and experiences needed for interaction among different, yet related disciplines. To my pleasant surprise, nearly everyone invited came to San Francisco to participate.

Protein Crosslinking

Mendel Friedman
Protein Crosslinking Book PDF

Author : Mendel Friedman
Publisher : Springer
Page : 740 pages
File Size : 41,9 Mb
Release : 2013-06-27
Category : Science
ISBN : 1475791151

Get Book

Protein Crosslinking by Mendel Friedman Pdf

The word crosslinking implies durable combination of usually large, distinct elements at specific places to create a new entity that has different properties as a result of the union. In the case of proteins, such crosslinking often results in important changes in chemical, physical, functional, nutritional, and biome dical properties, besides physical properties simply related to molecular size and shape. (Nucleic acids, carbohydrates~ glyco proteins, and other biopolymers are correspondingly affected.) Since proteins are ubiquitous, the consequences of their crosslin king are widespread and often profound. Scientists from many dis ciplines including organic chemistry, biochemistry, protein chemis try, food science, nutrition, radiation biology, pharmacology, physiology, medicine, and dentistry are, therefore, very much inte rested in protein crosslinking reactions and their implications. Because protein crosslinking encompasses so many disciplines, in organizing the Symposium on Nutritional and Biochemical Consequences of Protein Crosslinking sponsored by the Protein Subdivision of the Division of Agricultural and Food Chemistry of the American Chemical Society, I sought participants with the broadest possible range of interests, yet with a common concern for theoretical and practical aspects of protein crosslinking. An important function of a symposium is to catalyze progress by bringing together ideas and experiences needed for interaction among different, yet related disciplines. To my pleasant surprize, nearly everone invited came to San Francisco to participate.

Enzyme Immunoassays

S.S. Deshpande
Enzyme Immunoassays Book PDF

Author : S.S. Deshpande
Publisher : Springer Science & Business Media
Page : 473 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461311690

Get Book

Enzyme Immunoassays by S.S. Deshpande Pdf

This unique reference provides a pragmatic approach to the development of successful commercial immunodiagnostic products based on enzyme immunoessay technology. Presenting both the basic and applied principles, Enzyme Immunoassays gathers information on all aspects of this process, from the initial conceptualization to the introduction of the product to the market.

Bioconjugate Techniques

Greg T. Hermanson
Bioconjugate Techniques Book PDF

Author : Greg T. Hermanson
Publisher : Academic Press
Page : 1166 pages
File Size : 49,8 Mb
Release : 2013-07-25
Category : Science
ISBN : 9780123822406

Get Book

Bioconjugate Techniques by Greg T. Hermanson Pdf

Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Chemical Linkers in Antibody-Drug Conjugates (ADCs)

Floris van Delft,John M. Lambert
Chemical Linkers in Antibody Drug Conjugates ADCs Book PDF

Author : Floris van Delft,John M. Lambert
Publisher : Royal Society of Chemistry
Page : 477 pages
File Size : 49,8 Mb
Release : 2021-12-22
Category : Medical
ISBN : 9781839162633

Get Book

Chemical Linkers in Antibody-Drug Conjugates (ADCs) by Floris van Delft,John M. Lambert Pdf

Chemical Linkers in Antibody-Drug Conjugates aims to shine a detailed light on the various key attributes of chemical linkers in ADCs, for drug-to-antibody ratio, for stability, for release mechanism of payload, for pharmacokinetics, for stability determination, and for efficacy and safety.

Bioconjugation

Mohammed Aslam,Alastair Dent
Bioconjugation Book PDF

Author : Mohammed Aslam,Alastair Dent
Publisher : Unknown
Page : 856 pages
File Size : 50,7 Mb
Release : 1998
Category : Biochemistry
ISBN : PSU:000056868074

Get Book

Bioconjugation by Mohammed Aslam,Alastair Dent Pdf

Recent years have seen an enormous increase in the use of protein reagents in the biological and medical sciences. Enzyme conjugates and immobilised proteins are fundamental to many diagnostic applications, and existing therapeutic advances are being made using a range of approaches based on antibody conjugates. Protein conjugation techniques are central to the development of these reagents.

The Evolution from Protein Chemistry to Proteomics

Roger L. Lundblad
The Evolution from Protein Chemistry to Proteomics Book PDF

Author : Roger L. Lundblad
Publisher : CRC Press
Page : 312 pages
File Size : 46,6 Mb
Release : 2005-10-14
Category : Medical
ISBN : 9781420036404

Get Book

The Evolution from Protein Chemistry to Proteomics by Roger L. Lundblad Pdf

Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension

Mass Spectrometry in Structural Biology and Biophysics

Igor A. Kaltashov,Stephen J. Eyles
Mass Spectrometry in Structural Biology and Biophysics Book PDF

Author : Igor A. Kaltashov,Stephen J. Eyles
Publisher : John Wiley & Sons
Page : 312 pages
File Size : 50,9 Mb
Release : 2012-04-03
Category : Science
ISBN : 9780470937792

Get Book

Mass Spectrometry in Structural Biology and Biophysics by Igor A. Kaltashov,Stephen J. Eyles Pdf

The definitive guide to mass spectrometry techniques in biology and biophysics The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art. Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics, structural biology, and biopharmaceuticals, the book is a practical guide to understanding the role of MS techniques in biophysical research. Designed to meet the needs of both academic and industrial researchers, it makes mass spectrometry accessible to professionals in a range of fields, including biopharmaceuticals. This new edition has been significantly expanded and updated to include the most recent experimental methodologies and techniques, MS applications in biophysics and structural biology, methods for studying higher order structure and dynamics of proteins, an examination of other biopolymers and synthetic polymers, such as nucleic acids and oligosaccharides, and much more. Featuring high-quality illustrations that illuminate the concepts described in the text, as well as extensive references that enable the reader to pursue further study, Mass Spectrometry in Structural Biology and Biophysics is an indispensable resource for researchers and graduate students working in biophysics, structural biology, protein chemistry, and related fields.