Chromatin Remodelling

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Chromatin Remodelling

Author : Danuta Radzioch
Publisher : BoD – Books on Demand
Page : 237 pages
File Size : 42,9 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9789535110873

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Chromatin Remodelling by Danuta Radzioch Pdf

The term "chromatin remodelling" is widely used to describe changes in chromatin structure which is controlled by histone-modifying enzymes, chromatin remodelling complexes, non-histone DNA-binding proteins and noncoding RNAs. Many human diseases such as cancer, various genetic syndromes, autism and infectious disease have been linked to the disruption of these control processes by genetic, environmental or microbial factors. Therefore, to unravel the mechanisms by which they operate is one of the most exciting and rapid developing fields of modern biology and will contribute to new ways in treatment of these diseases. The chapters in this book will focus on recent advances in our understanding of the mechanisms that govern the dynamic structural of chromatin, thereby providing important insights into gene regulation, DNA repair, and human diseases.

Chromatin Remodelling and Immunity

Author : Anonim
Publisher : Academic Press
Page : 318 pages
File Size : 41,7 Mb
Release : 2017-01-02
Category : Medical
ISBN : 9780128123935

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Chromatin Remodelling and Immunity by Anonim Pdf

Chromatin Remodelling and Immunity, Volume 106, the latest release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in protein chemistry and structural biology Written by authorities in the field Targeted to a wide audience of researchers, specialists, and students

Chromatin and Chromatin Remodeling Enzymes

Author : Carl Wu,C. David Allis
Publisher : Elsevier
Page : 546 pages
File Size : 51,6 Mb
Release : 2004-04-07
Category : Science
ISBN : 9780080497150

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Chromatin and Chromatin Remodeling Enzymes by Carl Wu,C. David Allis Pdf

DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription. Genetic assays of chromatin modification and remodeling Histone modifying enzymes ATP-dependent chromatin remodeling enzymes

Chromatin and Chromatin Remodeling Enzymes

Author : Carl Wu,C. David Allis
Publisher : Elsevier
Page : 458 pages
File Size : 43,6 Mb
Release : 2004-03-07
Category : Science
ISBN : 9780080497143

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Chromatin and Chromatin Remodeling Enzymes by Carl Wu,C. David Allis Pdf

DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodelling enzymes play an important role in gene transcription.

The Dictionary of Genomics, Transcriptomics and Proteomics

Author : Guenter Kahl
Publisher : John Wiley & Sons
Page : 2742 pages
File Size : 51,5 Mb
Release : 2015-05-21
Category : Science
ISBN : 9783527678648

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The Dictionary of Genomics, Transcriptomics and Proteomics by Guenter Kahl Pdf

Now in its fifth edition and for the first time available as an electronic product with all entries cross-linked. This very successful long-seller has once again been thoroughly updated and greatly expanded. It now contains over 13,000 entries, and comprehensively covering genomics, transcriptomics, and proteomics. Each entry contains an extensive explanation, including a comprehensive listing of synonyms and acronyms, and all formulas have been redrawn to create a uniform style, while most of the figures are custom designed for this dictionary. The ultimate reference for all terms in the -omics fields.

Epigenetics and Health

Author : Michelle McCulley
Publisher : John Wiley & Sons
Page : 165 pages
File Size : 49,5 Mb
Release : 2024-04-02
Category : Science
ISBN : 9781119307983

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Epigenetics and Health by Michelle McCulley Pdf

Epigenetics and Health An incisive and contemporary discussion of epigenetic phenomena applied to human health and disease Epigenetics and Health: A Practical Guide delivers a thorough and insightful exploration of the basic principles of gene function, gene regulation, and gene expression. The author explains how epigenetic modifications alter gene expression and demonstrate the role played by environmental factors—including nutrition, exercise, toxins, and stress—in gene regulation, as well as their potential health consequences. The book presents current methods for analyzing epigenetic variation, including NGS applications and bioinformatic analysis. Readers will be encouraged to question, analyze, and critically appraise the literature on epigenetics to further develop their understanding. They’ll also find: Explorations of epigenetic mechanisms, homeostasis, and the potential for manipulating the epigenome Practical discussions of methods for epigenetic analyses How to address cancer epigenetics, mental health epigenetics, and guidance on developing an epigenetics research project Epigenetics and Health: A Practical Guide will benefit practicing geneticists and medical geneticists seeking insights into epigenetic phenomena applied to human health and disease.

Genetics

Author : Daniel L. Hartl,Elizabeth W. Jones
Publisher : Jones & Bartlett Learning
Page : 804 pages
File Size : 44,7 Mb
Release : 2009
Category : Medical
ISBN : 076375868X

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Genetics by Daniel L. Hartl,Elizabeth W. Jones Pdf

This handbook covers all dimensions of breast cancer prevention, diagnosis, and treatment for the non-oncologist. A special emphasis is placed on the long term survivor.

Medical Biotechnology

Author : Judit Pongracz,Mary Keen
Publisher : Elsevier Health Sciences
Page : 207 pages
File Size : 50,6 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9780080451350

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Medical Biotechnology by Judit Pongracz,Mary Keen Pdf

"Biotechnology encompasses the variety of methods available for manipulating living cells and organisms. It is having an increasing impact on all aspects of medicine, from helping in the understanding of the aetiology of disease, to its diagnosis and treatment. This growing importance of medical biotechnology means that a general understanding of this rapidly advancing field is essential for all medical graduates and medical scientists. This book places emphasis on the medical applications of biotechnology, rather than the details fo the experimental techniques"--Back cover.

Chromatin and Chromatin Remodeling Enzymes, Part A

Author : Carl Wu,C. David Allis
Publisher : Elsevier
Page : 579 pages
File Size : 55,9 Mb
Release : 2004-02-20
Category : Science
ISBN : 9780080497136

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Chromatin and Chromatin Remodeling Enzymes, Part A by Carl Wu,C. David Allis Pdf

DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodellng enzymes play an important role in gene transcription. *Histone Bioinformatics *Biochemistry of histones, nucleosomes and chromatin *Molecular cytology of chromatin functions

Chromatin Remodeling

Author : Randall H. Morse
Publisher : Humana Press
Page : 0 pages
File Size : 53,6 Mb
Release : 2011-12-21
Category : Medical
ISBN : 1617794767

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Chromatin Remodeling by Randall H. Morse Pdf

Chromatin is of central importance to gene regulation in eukaryotes. Reflecting this singular role for chromatin, numerous approaches have evolved in the laboratory over the past three decades to study chromatin structure and its alterations. Methods of investigating chromatin remodeling, whether in changes in nucleosome structure or position with respect to the incorporated DNA or in histone modifications, have progressed rapidly over the recent years. In Chromatin Remodeling: Methods and Protocols, expert researchers contribute chapters which include methods for investigating chromatin remodeling in vitro and in vivo, in yeast, plants, and mammalian cells, and at local and global levels. Both gene-specific and genome-wide approaches are covered, and in recognition of the increasing prevalence of the latter type of study, the final two chapters focus on bioinformatic/computational approaches to analyzing genome-wide data on chromatin structure. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and essential, Chromatin Remodeling: Methods and Protocols serves as a key source of clear techniques as well as a collection of chapters that can inspire future techniques in this vital field of study.

Phosphoinositides in Subcellular Targeting and Enzyme Activation

Author : Harald Stenmark
Publisher : Springer Science & Business Media
Page : 209 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642188053

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Phosphoinositides in Subcellular Targeting and Enzyme Activation by Harald Stenmark Pdf

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Fundamentals of Chromatin

Author : Jerry L. Workman,Susan M. Abmayr
Publisher : Springer Science & Business Media
Page : 594 pages
File Size : 49,8 Mb
Release : 2013-12-04
Category : Medical
ISBN : 9781461486244

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Fundamentals of Chromatin by Jerry L. Workman,Susan M. Abmayr Pdf

​​​​​​​​​​​​​While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. ​Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists ​and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.

Epigenetics, Brain and Behavior

Author : Paolo Sassone Corsi,Yves Christen
Publisher : Springer Science & Business Media
Page : 171 pages
File Size : 55,6 Mb
Release : 2012-08-28
Category : Medical
ISBN : 9783642279126

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Epigenetics, Brain and Behavior by Paolo Sassone Corsi,Yves Christen Pdf

What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone variants, microRNA metabolic pathways and non-histone proteins modifications. Thus, while neuronal plasticity is rightly thought to be intimately associated to genomic control, it is critical to appreciate that there is much more to the genome than DNA sequence. Recent years have seen spectacular advances in the field of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigenetic regulation to brain functions has been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molecular mechanisms implicated in epigenetic control and how these may operate in concert. It will be critical to unravel how specificity is achieved. Importantly, specific modifications seem to mediate both developmental processes and adult brain functions, such as synaptic plasticity and memory. Many aspects of the research in neurosciences and endocrinology during the upcoming decade will be dominated by the deciphering of epigenetic control. This book constitutes a compendium of the most updated views in the field.

Oogenesis

Author : Marie-Helene Verlhac,Anne Villeneuve
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 46,7 Mb
Release : 2010-03-04
Category : Science
ISBN : 0470687983

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Oogenesis by Marie-Helene Verlhac,Anne Villeneuve Pdf

Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. Topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction. This volume is an essential resource for all students, researchers and clinicians in developmental and reproductive biology. Key features: Reaches beyond the study of simply meiosis to cover all aspects of oogenesis Synthesizes recent advances in the field, drawing on studies from different model species Chapter sequence designed to follow the time line in vivo Written by an international panel of expert researchers

Fungal RNA Biology

Author : Ane Sesma,Tobias von der Haar
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 49,5 Mb
Release : 2014-04-15
Category : Science
ISBN : 9783319056876

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Fungal RNA Biology by Ane Sesma,Tobias von der Haar Pdf

This book presents an overview of the RNA networks controlling gene expression in fungi highlighting the remaining questions and future challenges in this area. It covers several aspects of the RNA-mediated mechanisms that regulate gene expression in model yeasts and filamentous fungi, organisms of great importance for industry, medicine and agriculture. It is estimated that there are more than one million fungal species on the Earth. Despite their diversity (saprophytic, parasitic and mutualistic), fungi share common features distinctive from plants and animals and have been grouped taxonomically as an independent eukaryotic kingdom. In this book, 15 chapters written by experts in their fields cover the RNA-dependent processes that take place in a fungal cell ranging from formation of coding and non-coding RNAs to mRNA translation, ribosomal RNA biogenesis, gene silencing, RNA editing and epigenetic regulation.