Chromatographic And Membrane Processes In Biotechnology

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Chromatographic and Membrane Processes in Biotechnology

C.A. Costa,Joaquim S. Cabral
Chromatographic and Membrane Processes in Biotechnology Book PDF

Author : C.A. Costa,Joaquim S. Cabral
Publisher : Springer Science & Business Media
Page : 465 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401134705

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Chromatographic and Membrane Processes in Biotechnology by C.A. Costa,Joaquim S. Cabral Pdf

Separation processes in biotechnology are of increasing industrial importance since they entail the major costs of bioprocessing especially when high purity is required. Chromatography and membranes are two of the most important technologies used for direct treatment of fermentation broths as well as for high resolution steps in product purification. The theoretical foundations of chromatographic and membrane processes are well understood for the case of small molecules. Nevertheless there is a need to adapt and further develop that knowledge to the processing of large biological molecules. This is being achieved with the contribution of other areas like molecular biology and materials science. The objective of this NATO Advanced Study Institute is to present an updated treatment of the fundamentals of chromatographic and membrane processes with special relevance in bioprocessing.This volume collects the lectures presented at this Institute. The lectures are arranged in five chapters. Chapter I deals with chromatographic processes covering topics like equilibrium, kinetics and contacting devices. Membrane processes and some applications in biotechnology are treated in chapter 2. Chapter 3 is devoted to affinity chromatographic and membrane processes. Chapter 4 considers the current developments on chromatographic supports and membranes both from the constitutive materials and form points of view. Scale-up, optimization and reaction/separation integration are the topics covered in chapter 5. We are very grateful to all lecturers and participants that made possible this Institute. Financial support from NATO Scientific Affairs Division, INIC, JNICT, FLAD, University of Ac;ores and DRT Ac;ores is gratefully acknowledged.

Membrane Processes in Biotechnology and Pharmaceutics

Catherine Charcosset
Membrane Processes in Biotechnology and Pharmaceutics Book PDF

Author : Catherine Charcosset
Publisher : Elsevier
Page : 349 pages
File Size : 42,8 Mb
Release : 2012-03-14
Category : Medical
ISBN : 9780444563347

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Membrane Processes in Biotechnology and Pharmaceutics by Catherine Charcosset Pdf

Chapter 1: Principles on membrane and membrane processes -- Chapter 2: Ultrafiltration -- Chapter 3: Microfiltration -- Chapter 4: Virus Filtration -- Chapter 5: Membrane chromatography -- Chapter 6: Membranes for the Preparation of Emulsions and Particles -- Chapter 7: Other Membrane Processes -- Chapter 8: Some Perspectives.

Membrane Separations in Biotechnology

William K. Wang
Membrane Separations in Biotechnology Book PDF

Author : William K. Wang
Publisher : CRC Press
Page : 432 pages
File Size : 40,9 Mb
Release : 2001-04-03
Category : Science
ISBN : 9781482289886

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Membrane Separations in Biotechnology by William K. Wang Pdf

This text details the relationship between membrane technology and bioprocesses, discussing applications. This second edition refines and optimizes key features of the first edition - and features new illustrative case studies. The book examines advantages and disadvantages of using standard and new membrane technologies; analyzes a wide range of a

Handbook of Membrane Separations

Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena
Handbook of Membrane Separations Book PDF

Author : Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena
Publisher : CRC Press
Page : 1210 pages
File Size : 43,5 Mb
Release : 2008-07-07
Category : Science
ISBN : 9781420009484

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Handbook of Membrane Separations by Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena Pdf

The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological Applications provides detailed information on membrane separation technologies as they have evolved over the past decades. To provide a basic understanding of membrane technology, this book documents the developments dealing with these technologies. It explo

Separation Processes in Biotechnology

Juan A. Asenjo
Separation Processes in Biotechnology Book PDF

Author : Juan A. Asenjo
Publisher : CRC Press
Page : 824 pages
File Size : 55,5 Mb
Release : 2020-08-26
Category : Science
ISBN : 9781000104325

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Separation Processes in Biotechnology by Juan A. Asenjo Pdf

Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Membrane Processes in Biotechnology and Pharmaceutics

Catherine Charcosset
Membrane Processes in Biotechnology and Pharmaceutics Book PDF

Author : Catherine Charcosset
Publisher : Elsevier
Page : 349 pages
File Size : 43,6 Mb
Release : 2012-01-25
Category : Technology & Engineering
ISBN : 9780444563378

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Membrane Processes in Biotechnology and Pharmaceutics by Catherine Charcosset Pdf

Membrane processes are increasingly used in pharmaceutical and biochemical engineering and biotechnology for concentration and purification, synthesis of molecules and drug delivery systems, and support for biochemical reactions. This book provides a state-of-the art overview of the classical membrane processes used in pharmaceutical and biochemical engineering and biotechnology, such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors. It describes the general rules (principles, choice of configurations, membranes, parameters, etc.), recent developments (fouling control, increase permeate flux and selectivity, etc.), applications, and theoretical descriptions. Further, it presents emerging processes such as solvent resistant nanofiltration and membrane crystallization. Presents classical membrane processes such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors Presents emerging processes such as solvent resistant nanofiltration and membrane crystallization Gives a complete description of each technique (principles, membrane materials and devices, fouling control, and theoretical description) Contains numerous examples of applications Includes a uniform notation throughout the book enhancing the presentation and understanding of the content Includes extensive list of references

Current Trends and Future Developments on (Bio-) Membranes

Angelo Basile,Catherine Charcosset
Current Trends and Future Developments on Bio Membranes Book PDF

Author : Angelo Basile,Catherine Charcosset
Publisher : Elsevier
Page : 365 pages
File Size : 40,6 Mb
Release : 2018-10-16
Category : Technology & Engineering
ISBN : 9780128136072

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Current Trends and Future Developments on (Bio-) Membranes by Angelo Basile,Catherine Charcosset Pdf

Current Trends and Future Developments on (Bio-) Membranes: Membrane Processes in the Pharmaceutical and Biotechnological field presents the main membrane techniques along with their basic principles, mode of operations, and applications. It covers well-known techniques such as ultrafiltration and membrane chromatography, while also exploring emerging membrane technologies which are finding their way in pharmaceutical and biotechnology industries, including membrane emulsification, membrane bioreactors, and solvent-resistant nanofiltration. State-of-the-art applications of membrane systems in areas such as drug delivery and virus removal are also investigated by leading experts in the field. Current Trends and Future Developments on (Bio-) Membranes: Membrane Processes in the Pharmaceutical and Biotechnological field is a definitive reference for academics, post-graduates, and researchers in the subjects of biochemical engineering, pharmaceutics, and biotechnology. It is also useful to R&D companies and institutions in these areas, specifically those interested in bioseparations, biopurification, bioproduction, and drug delivery. Offers an overview of classical membrane-based separation techniques such as ultrafiltration, microfiltration and virus filtration Discusses emerging membrane-based separation techniques such as nofiltration in the presence of solvent, membrane emulsification and membrane crystallization Outlines their applications to bioseparation, biopurification and bioproduction Includes examples in the production of vaccines, antibiotics, biomolecules, drugs, DNA and cells Lists membranes systems for drug delivery like liposomes, nanocapsules and bilayer membranes

Highly Selective Separations in Biotechnology

G. Street
Highly Selective Separations in Biotechnology Book PDF

Author : G. Street
Publisher : Springer Science & Business Media
Page : 242 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401113229

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Highly Selective Separations in Biotechnology by G. Street Pdf

Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.

Bioseparation and Bioprocessing, Volume I: Biochromatography - Membrane Separations - Modeling - Validation. Volume II: Processing - Quality and Characterisation - Economics, Safety and Hygiene

G. Subramanian
Bioseparation and Bioprocessing Volume I Biochromatography Membrane Separations Modeling Validation Volume II Processing Quality and Characterisation Economics Safety and Hygiene Book PDF

Author : G. Subramanian
Publisher : Wiley-VCH
Page : 568 pages
File Size : 44,7 Mb
Release : 1998
Category : Science
ISBN : UOM:39015043114761

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Bioseparation and Bioprocessing, Volume I: Biochromatography - Membrane Separations - Modeling - Validation. Volume II: Processing - Quality and Characterisation - Economics, Safety and Hygiene by G. Subramanian Pdf

Rapid developments in biotechnology create a demand for practical, up-to-date reviews written by and for experts in industry. This compact handbook provides all relevant up-to-date information on important bioseparation and bioprocessing techniques that are actively applied in the biotechnology industries. The handbook presents an applications-orientated overview on - case studies and general strategies for quality control and characterization - detailed guidelines on developing economic and technically feasible bioseparation schemes - strategies and methods for intracellular bioproduct release - chromatographic and membrane downstream processes used in biotechnology - applications of modern non-invasive methods such as neural networks for on-line estimation and control of fermentation variables on an industrial scale - a practical, commercially-relevant guide to biosafety and many more aspects which are indispensible for present and future industrial success.

Process Scale Bioseparations for the Biopharmaceutical Industry

Abhinav A. Shukla,Mark R. Etzel,Shishir Gadam
Process Scale Bioseparations for the Biopharmaceutical Industry Book PDF

Author : Abhinav A. Shukla,Mark R. Etzel,Shishir Gadam
Publisher : CRC Press
Page : 600 pages
File Size : 44,9 Mb
Release : 2006-07-07
Category : Medical
ISBN : 9781420016024

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Process Scale Bioseparations for the Biopharmaceutical Industry by Abhinav A. Shukla,Mark R. Etzel,Shishir Gadam Pdf

The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceut

Bioprocess Engineering

Pau Loke Show,Chien Wei Ooi,Tau Chuan Ling
Bioprocess Engineering Book PDF

Author : Pau Loke Show,Chien Wei Ooi,Tau Chuan Ling
Publisher : CRC Press
Page : 186 pages
File Size : 42,9 Mb
Release : 2019-06-13
Category : Medical
ISBN : 9780429882517

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Bioprocess Engineering by Pau Loke Show,Chien Wei Ooi,Tau Chuan Ling Pdf

Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Separations for Biotechnology 2

D. Leo Pyle
Separations for Biotechnology 2 Book PDF

Author : D. Leo Pyle
Publisher : Springer Science & Business Media
Page : 659 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400907836

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Separations for Biotechnology 2 by D. Leo Pyle Pdf

The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.

Separation Processes in the Food and Biotechnology Industries

A S Grandison,Alistair S. Grandison,M J Lewis
Separation Processes in the Food and Biotechnology Industries Book PDF

Author : A S Grandison,Alistair S. Grandison,M J Lewis
Publisher : Woodhead Publishing
Page : 306 pages
File Size : 55,8 Mb
Release : 1996-01-15
Category : Medical
ISBN : 1855732874

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Separation Processes in the Food and Biotechnology Industries by A S Grandison,Alistair S. Grandison,M J Lewis Pdf

This book reviews methods and techniques for separating food components and products of the biotechnology industry. The introduction focuses on food composition and some of the conventional separation techniques. Subsequent chapters deal with each specific type or area of application individually and include information on the basic principles, industrial equipment available, commercial applications and an overview of research and development.

Effective Industrial Membrane Processes: Benefits and Opportunities

M.K. Turner
Effective Industrial Membrane Processes Benefits and Opportunities Book PDF

Author : M.K. Turner
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 42,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401136822

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Effective Industrial Membrane Processes: Benefits and Opportunities by M.K. Turner Pdf

The aim of the Technical Advisory Committee, in planning the c~:>Dtent of this meeting, was to illustrate the range of separation processes in which the use of membranes was practical and effective at an industrial scale. As Professor Strathmann reveals, the market for process equipment built around membranes is now worth about $5x1(f annually, and it seemed important to review this technology, and to point the direction of future technical advances. All but the most critical reader should find some items of interest. The Committee would admit to not fulftlling all of thier aims, although those delegates who attended the meeting in Edinburgh judged it a success. In the event it provided representative examples of processes from the food and beverage industry, from water treatment, and from the chemical industry, of which the removal of alcohol from fermented beverages, shipboard desalination and solvent recovery are three. The major uses of charged membranes and sterile processes are not covered, nor 9 is the largest market, $1.2x10 annually, for artificial kidney dialysis. However, it is interesting to see artificial kidney now finding an alternative use as a reactor for the production of monoclonal antibodies. We are also reminded by Professor Michel of the importance and efficiency of natural membranes in the kidney under conditions where fouling is crucial to their performance and enhances their selectivity.

Handbook of Membrane Separations

Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena
Handbook of Membrane Separations Book PDF

Author : Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena
Publisher : CRC Press
Page : 868 pages
File Size : 44,8 Mb
Release : 2015-04-09
Category : Science
ISBN : 9781466555587

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Handbook of Membrane Separations by Anil Kumar Pabby,Syed S.H. Rizvi,Ana Maria Sastre Requena Pdf

The Handbook of Membrane Separations: Chemical, Pharmaceutical, Food, and Biotechnological Applications, Second Edition provides detailed information on membrane separation technologies from an international team of experts. The handbook fills an important gap in the current literature by providing a comprehensive discussion of membrane application