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Separation Processes in Biotechnology by Juan A. Asenjo Pdf
Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations
Separation Processes in the Food and Biotechnology Industries by A S Grandison,Alistair S. Grandison,M J Lewis Pdf
This book reviews methods and techniques for separating food components and products of the biotechnology industry. The introduction focuses on food composition and some of the conventional separation techniques. Subsequent chapters deal with each specific type or area of application individually and include information on the basic principles, industrial equipment available, commercial applications and an overview of research and development.
Separations for Biotechnology 2 by D. Leo Pyle Pdf
The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.
Separation Processes in the Food and Biotechnology Industries by A.S. Grandison Pdf
From the Editors' Preface This book concentrates on the more recent methods and techniques for separating food components and products of the biotechnology industry. Each chapter deals with a specific type or area of application and includes information on the basic principles, industrial equipment available, commercial applications, and an overview of current research and development. Much of the emphasis is on extraction of macromolecules, increasing the added value of foods and recovering valuable components from by-products and fermentation media. Many of the methods discussed are now in commercial practice, while others are being vigorously researched. Separation and filtration technology is of major importance in food processing and biotechnology. This new book provides a very detailed examination of the most important, advanced separation processes now in use. Each chapter is prepared by a specialist or specialists in the type of separation discussed. Each separation method is related to practical commercial applications.
Separation and Purification Techniques in Biotechnology by Frederick Dechow Pdf
This book describes separation and purification techniquesùadsorption, ion exchange and liquid chromatography on solid supportsùused for fermentation and biochemical feedstreams. Emphasis is placed on basic sorption theory, laboratory evaluation techniques, sorptive materials and their characteristics, scale-up of laboratory techniques, and their industrial applications. Each chapter contains specific examples illustrating the use of purification techniques in biotechnology processes.
Bioseparation Engineering by Ajay Kumar,Abhishek Awasthi Pdf
Bioseparation Engineering is meant for undergraduate and the postgraduate student community pursuing careers in Life Sciences. It concentrates on the more recent methods and techniques for separating components and products of the biotechnology industry. Each chapter deals with a specific type or area of application and includes information on the basic principles, industrial equipment available, commercial applications and an overview of current research and development. Main objective of the book is to provide in-depth knowledge of the subject in an interesting and paramount simple way
Centrifugal Separations in Biotechnology by Wallace Woon-Fong Leung Pdf
Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more
Chromatographic and Membrane Processes in Biotechnology by C.A. Costa,Joaquim S. Cabral Pdf
Separation processes in biotechnology are of increasing industrial importance since they entail the major costs of bioprocessing especially when high purity is required. Chromatography and membranes are two of the most important technologies used for direct treatment of fermentation broths as well as for high resolution steps in product purification. The theoretical foundations of chromatographic and membrane processes are well understood for the case of small molecules. Nevertheless there is a need to adapt and further develop that knowledge to the processing of large biological molecules. This is being achieved with the contribution of other areas like molecular biology and materials science. The objective of this NATO Advanced Study Institute is to present an updated treatment of the fundamentals of chromatographic and membrane processes with special relevance in bioprocessing.This volume collects the lectures presented at this Institute. The lectures are arranged in five chapters. Chapter I deals with chromatographic processes covering topics like equilibrium, kinetics and contacting devices. Membrane processes and some applications in biotechnology are treated in chapter 2. Chapter 3 is devoted to affinity chromatographic and membrane processes. Chapter 4 considers the current developments on chromatographic supports and membranes both from the constitutive materials and form points of view. Scale-up, optimization and reaction/separation integration are the topics covered in chapter 5. We are very grateful to all lecturers and participants that made possible this Institute. Financial support from NATO Scientific Affairs Division, INIC, JNICT, FLAD, University of Ac;ores and DRT Ac;ores is gratefully acknowledged.
Engineering Processes for Bioseparations by LAURENCE R. WEATHERLEY Pdf
The use of biotechnology in chemical synthesis offers up numerous advantages to the engineer in the process industries, but it also presents a number of fundamental challenges and difficulties which impinge directly on separation process requirements. The use of biochemical separations has grown significantly during the past decade, and is especially used in process industries such as healthcare and food processing. However it is becoming increasingly more important in areas such as recycling and waste-water treatment and as industry shifts towards cleaner processes biochemical separations will continue to grow. The two main objectives of this book are to focus on the application of existing separation process techniques to the recovery and purification of biologically derived products and to examine the state of knowledge of new techniques which have future potential. Within these objectives the complexities and breadth of problems associated with biological separations are discussed, specific engineering techniques are featured and their adaptation to biochemical separations are highlighted.
Centrifugal Separations in Biotechnology by Wallace Woon-Fong Leung Pdf
This book is the first devoted to centrifugal separation in biotechnology. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. A comprehensive guide to centrifuges, their optimal development and operation in the biotechnology industry Applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Provides detailed process information and data to assist in the development of particular processes from existing systems Explores the commercial applications of centrifuges in biotechnology Guidance on troubleshooting and optimizing centrifuges
Membrane Processes in Separation and Purification by J.G. Crespo,Karl W. Böddeker Pdf
The chapters of this book are based upon lectures presented at the NATO Advanced Study Institute on Membrane Processes in Separation and Purification (March 21 - April 2, 1993, Curia, Portugal), organized as a successor and update to a similar Institute that took place 10 years ago (p.M.Bungay, H.K. Lonsdale, M.N. de Pinho (Eds.): Synthetic Membranes: Science, Engineering and Applications, NATO ASI Series, Reidel, Dordrecht, 1986). The decade between the two NATO Institutes witnesses the transition from individually researched membrane processes to an applied and established membrane separation technology, as is reflected by the contents of the corresponding proceeding volumes. By and large, the first volume presents itself as a textbook on membrane processes, still valid, while the present volume focuses on areas of separation need as amenable to membrane processing: Biotechnology and Environmental Technology. Accordingly, the contributions to this volume are grouped into "Membranes in Biotechnology" (11 papers), "Membranes in Environmental Technology" (6 papers), and "New Concepts" (4 papers). This is followed by one contribution each on "Energy Requirements" and "Education", i.e., membrane processes within an academic curriculum. The book thus amounts to a state of the art of applied membrane processing and may well augment the more fundamental approach of its predecessor.
Industrial Separation Processes by André B. de Haan,Hans Bosch Pdf
Separation operations are crucial throughout the process industry with respect to energy consumption, contribution to investments and ability to achieve the desired product with the right specifications. Our main objective in creating this graduate level textbook is to present an overview of the fundamentals underlying the most frequently used industrial separation methods. We focus on their physical principles and the basic computation methods that are required to assess their technical and economical feasibility. The textbook is organized into three main parts. Separation processes for homogeneous mixtures are treated in the parts on equilibrium based molecular separations and rate-controlled molecular separations. The part on mechanical separation technology presents an overview of the most important techniques for heterogeneous mixture separation. Each chapter provides a condensed overview of the most commonly used equipment types. The textbook is concluded with a final chapter on the main considerations in selecting an appropriate separation process for a separation task. As the design of separation processes can only be learned by doing, we have included exercises at the end of each chapter. Short answers are given at the end of this book; detailed solutions are given in a separate solution manual.
Authored by a team of respected scientists and technologists, this book covers many pharmaceutical and biotechnology separations methods currently in use. Practical applications and descriptions are offered for air elutriation, microporous filtration, ultrafiltration, phase partitioning, crystallization, and chromatographic technologies such as adsorption, affinity, chelate, ion-exchange, size-exclusion, template, hydrophobic interaction, biotransformations, and chiral separations. Containing hundreds of references and a complete index, this book is designed for research and development scientists, process optimization engineers, and quality control laboratory scientists as well as quality assurance professionals and others needing to understand current separation techniques.
Author : André B. de Haan,H. Burak Eral,Boelo Schuur Publisher : Walter de Gruyter GmbH & Co KG Page : 454 pages File Size : 51,6 Mb Release : 2020-07-06 Category : Science ISBN : 9783110654806
Industrial Separation Processes by André B. de Haan,H. Burak Eral,Boelo Schuur Pdf
Separation processes on an industrial scale account for well over half of the capital and operating costs in the chemical industry. Knowledge of these processes is key for every student of chemical or process engineering. This book is ideally suited to university teaching, thanks to its wealth of exercises and solutions. The second edition boasts an even greater number of applied examples and case studies as well as references for further reading.
