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Author : [Anonymus AC08273789]
Publisher : Unknown
Page : 128 pages
File Size : 53,6 Mb
Release : 1970
Category : Biology
ISBN : 0879699418
Monographs in areas of molecular, cell, and developmental biology, genetics, evolutionary biology, neuroscience, cancer biology, and molecular pathology.
Author : Fumiaki Uchiumi
Publisher : BoD – Books on Demand
Page : 214 pages
File Size : 48,7 Mb
Release : 2022-10-05
Category : Medical
ISBN : 9781803556215
Gene expression is dependent on multiple steps, including transcription, RNA processing, and translation. Importantly, recent studies revealed that gene expression is regulated by chromatin structures and non-coding RNA profiles. Elucidating the molecular mechanisms may contribute to the development of novel therapeutics for aging-related diseases, including cancer and neurodegenerative diseases. This book provides a comprehensive overview of gene expression and its role in human disease. It consists of nine chapters organized into two sections on molecular mechanisms in controlling gene expression and the relationships between transcriptional control and human disease.
Author : Saura C. Sahu
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 53,9 Mb
Release : 2016-10-13
Category : Science
ISBN : 9781119135432
A comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine Presented by internationally recognized investigators in this exciting field of scientific research Provides an insight into the current trends and future directions of research in this rapidly developing new field A valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and government
Author : John W. B. Hershey,Michael Mathews,Nahum Sonenberg,Cold Spring Harbor Laboratory
Publisher : Unknown
Page : 0 pages
File Size : 41,6 Mb
Release : 1996
Category : Genetic regulation
ISBN : 0879694580
A comprehensive account of recent research in translational control and the molecular mechanisms involved, focusing on the numerous control mechanisms observed in eukaryotes. Subjects include basic mechanisms; the role of phosphorylation; regulation by trans-acting proteins; effects of viral infection; and mRNA stability. Other topics include translational control mediated by upstream AUG codons; a comparative view of initiation site selection mechanisms; and genetics of mitochondrial translation. For researchers with interests in gene expression, RNA biology, and protein synthesis. Annotation copyright by Book News, Inc., Portland, OR
Author : Chris G. Antonopoulos,Nicolás Rubido,Antonio Batista,Murilo S. Baptista
Publisher : Frontiers Media SA
Page : 143 pages
File Size : 50,7 Mb
Release : 2021-02-09
Category : Science
ISBN : 9782889664726
Author : James D. Katz,Brian Walitt
Publisher : Elsevier Health Sciences
Page : 169 pages
File Size : 48,6 Mb
Release : 2016-11-24
Category : Medical
ISBN : 9780323496582
This issue of Clinics in Geriatric Medicine, guest edited by Drs. James D. Katz and Brian Walitt of the NIH, is devoted to Rheumatic Diseases in Older Adults. Articles in this outstanding issue include Rheumatology Pharmacotherapy Pearls for the General Practitioner; Sarcopenia - Pathogenesis and Management; Osteoporosis and Metabolic Bone Diseases; Osteoarthritis; Regional Rheumatic Disorders and Rehabilitation in Older Adults; Rheumatological Manifestations of Malignancy; Sjögren’s Syndrome; Cardiovascular Disease Risk in Patients with Rheumatic Diseases; Gaps in Aging Research as it Applies to Rheumatological Clinical Care; and Update on Crystal-induced Arthritides.
Author : Anonim
Publisher : Academic Press
Page : 430 pages
File Size : 40,9 Mb
Release : 2015-09-14
Category : Science
ISBN : 9780124166127
The Maternal-to-Zygotic Transition provides users with an expert accounting of the mechanisms and functions of this transition in a range of animal and plant models. The book provides critical information on how maternal gene products program the initial development of all animal and plant embryos, then undergoing a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over the developmental control. Maternal gene products program the initial development of all animal and plant embryos These then undergo a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over developmental control In this book, experts provide their insights into the mechanisms and functions of this transition in a range of animal and plant models.
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 624 pages
File Size : 54,9 Mb
Release : 2016-05-17
Category : Medical
ISBN : 9781476733531
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Author : Danny E. Miller,Angela L. Miller,R. Scott Hawley
Publisher : John Wiley & Sons
Page : 309 pages
File Size : 55,8 Mb
Release : 2023-07-25
Category : Science
ISBN : 9781394156283
GENETIC THEORY AND ANALYSIS Understand and apply what drives change of characteristic genetic traits and heredity Genetics is the study of how traits are passed from parents to their offspring and how the variation in those traits affects the development and health of the organism. Investigating how these traits affect the organism involves a diverse set of approaches and tools, including genetic screens, DNA and RNA sequencing, mapping, and methods to understand the structure and function of proteins. Thus, there is a need for a textbook that provides a broad overview of these methods. Genetic Theory and Analysis meets this need by describing key approaches and methods in genetic analysis through a historical lens. Focusing on the five basic principles underlying the field—mutation, complementation, recombination, segregation, and regulation—it identifies the full suite of tests and methodologies available to the geneticist in an age of flourishing genetic and genomic research. This second edition of the text has been updated to reflect recent advances and increase accessibility to advanced undergraduate students. Genetic Theory and Analysis, 2nd edition readers will also find: Detailed treatment of subjects including mutagenesis, meiosis, complementation, suppression, and more Updated discussion of epistasis, mosaic analysis, RNAi, genome sequencing, and more Appendices discussing model organisms, genetic fine-structure analysis, and tetrad analysis Genetic Theory and Analysis is ideal for both graduate students and advanced undergraduates undertaking courses in genetics, genetic engineering, and computational biology.
Author : Lluís Palou,Joseph L. Smilanick
Publisher : CRC Press
Page : 824 pages
File Size : 47,8 Mb
Release : 2019-10-28
Category : Technology & Engineering
ISBN : 9781351805896
Optimal distribution of fresh horticultural products entails prolonging their freshness and nutritional quality as long as possible after harvest. A major limitation to their marketing is decay after harvest, which is caused primarily by fungal pathogens. Postharvest Pathology of Fresh Horticultural Produce provides a comprehensive resource of information about the biology and control of postharvest diseases of many fresh horticultural products, citing sources from appropriate literature of any age, rather than only the most recent. The etiology and symptoms of postharvest diseases and the biology of postharvest pathogens are reviewed by leading experts, who are familiar with many of world’s most popular fresh fruits and vegetables and the diseases that affect them. Key aspects related to infection and epidemiology, methods to minimize postharvest decay losses, including use of conventional fungicides and alternative management strategies, harvest and handling practices, and other aspects are described for the most significant temperate, subtropical, and tropical fruits as well as fruit-like vegetables and leafy vegetables. Features: Provides comprehensive academic and practical reviews of postharvest diseases of fresh fruits and vegetables Discusses the economic importance, etiology, and epidemiology of the most significant postharvest diseases Includes quality color plates that allow the practical identification of disease symptoms Explains practical postharvest disease management actions, including the use of conventional fungicides and alternatives to their use The authors summarize a massive quantity of published information, and often apply their own considerable practical experience to identify and interpret the most significant information. This book is a valuable and comprehensive resource for industry professionals, academics, educators, students, consultants, pest control advisors, regulatory personnel, and others interested in this subject.
Author : Christophe Lavelle,Jean-Marc Victor
Publisher : Academic Press
Page : 618 pages
File Size : 46,6 Mb
Release : 2017-10-27
Category : Medical
ISBN : 9780128035030
Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds
Author : Tadeusz Jezierski,John Ensminger,L. E. Papet
Publisher : CRC Press
Page : 510 pages
File Size : 52,8 Mb
Release : 2016-04-20
Category : Law
ISBN : 9781482260274
The value of the canine nose is well-documented, and working dogs are being utilized for their olfactory skills in an increasing number of fields. Not only are dogs used by police, security, and the military, but they are also now used in forensic science, in medical detection of disease, in calculating population trends of endangered species and e
Author : Reinhard Krämer,Christine Ziegler
Publisher : Springer Science & Business Media
Page : 282 pages
File Size : 55,7 Mb
Release : 2014-03-13
Category : Science
ISBN : 9783642538391
This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing numbers of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternating access mechanism. This book brings together particularly significant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFS transporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies has made it possible to create a conclusive picture or more precisely, “a molecular movie”. Although we are still far from a complete molecular description of the alternating access mechanism, remarkable progress has been made from static snapshots towards membrane transport dynamics.
Author : Soni, Shivani
Publisher : IGI Global
Page : 856 pages
File Size : 49,7 Mb
Release : 2014-08-31
Category : Technology & Engineering
ISBN : 9781466663640
As a paradigm for the future, micro-scale technology seeks to fuse revolutionary concepts in science and engineering and then translate it into reality. Nanotechnology is an interdisciplinary field that aims to connect what is seen with the naked eye and what is unseen on the molecular level. The Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering examines the strengths and future potential of micro-scale technologies in a variety of industries. Highlighting the benefits, shortcomings, and emerging perspectives in the application of nano-scale technologies, this book is a comprehensive reference source for synthetic chemists, engineers, graduate students, and researchers with an interest in the multidisciplinary applications, as well as the ongoing research in the field.
Author : Jose C. Jimenez-Lopez
Publisher : BoD – Books on Demand
Page : 352 pages
File Size : 46,8 Mb
Release : 2017-12-06
Category : Technology & Engineering
ISBN : 9789535136217
The seed can be considered the most important plant reproductive element, as a dispersal unit for a successful reproduction in all gymnosperms and flowering plants. The formation of the seed is part of the process of reproduction in seed plants, starting with a mature ovule and following with the fertilization by pollen and some growth within the mother plant to the final outcome of an embryo developed from the zygote, the seed coat from the integuments of the ovule, and a nurturing endosperm in several species. Thanks to this key element as it is the seed, the spermatophytes now dominate all types of biological niches on land, from forests to grasslands, both in hot and cold climates. In this metadata information era, we have the chance for a deeper understanding of seed physiological and developmental processes in order to provide the fundamental basis for making plant (seed) biology research relevant and productive,coping with future challenges.