Combinatorial Pattern Matching Algorithms In Computational Biology Using Perl And R

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Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R

Author : Gabriel Valiente
Publisher : CRC Press
Page : 370 pages
File Size : 50,7 Mb
Release : 2009-04-08
Category : Computers
ISBN : 9781420069747

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Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R by Gabriel Valiente Pdf

Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis of genomic, transcriptomic, proteomic, metabolomic

Statistics and Data Analysis for Microarrays Using R and Bioconductor

Author : Sorin Draghici
Publisher : CRC Press
Page : 1036 pages
File Size : 44,9 Mb
Release : 2016-04-19
Category : Computers
ISBN : 9781439809761

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Statistics and Data Analysis for Microarrays Using R and Bioconductor by Sorin Draghici Pdf

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on,

Combinatorial Pattern Matching

Author : Gregory Kucherov,Esko Ukkonen
Publisher : Springer
Page : 370 pages
File Size : 52,5 Mb
Release : 2009-06-18
Category : Computers
ISBN : 9783642024412

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Combinatorial Pattern Matching by Gregory Kucherov,Esko Ukkonen Pdf

This book constitutes the refereed proceedings of the 20th Annual Symposium on Combinatorial Pattern Matching, CPM 2009, held in Lille, France in June 2009. The 27 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 63 submissions. The papers address all areas related to combinatorial pattern matching and its applications, such as coding and data compression, computational biology, data mining, information retrieval, natural language processing, pattern recognition, string algorithms, string processing in databases, symbolic computing and text searching.

Combinatorial Pattern Matching

Author : Paolo Ferragina,Gad M. Landau
Publisher : Springer Science & Business Media
Page : 327 pages
File Size : 52,6 Mb
Release : 2008-06-03
Category : Computers
ISBN : 9783540690665

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Combinatorial Pattern Matching by Paolo Ferragina,Gad M. Landau Pdf

This book constitutes the refereed proceedings of the 19th Annual Symposium on Combinatorial Pattern Matching, CPM 2008, held in Pisa, Italy, in June 2008. The 25 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 78 submissions. The papers address all areas related to combinatorial pattern matching and its applications, such as coding and data compression, computational biology, data mining, information retrieval, natural language processing, pattern recognition, string algorithms, string processing in databases, symbolic computing and text searching.

Biological Computation

Author : Ehud Lamm,Ron Unger
Publisher : CRC Press
Page : 346 pages
File Size : 48,6 Mb
Release : 2011-05-25
Category : Science
ISBN : 9781420087956

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Biological Computation by Ehud Lamm,Ron Unger Pdf

The area of biologically inspired computing, or biological computation, involves the development of new, biologically based techniques for solving difficult computational problems. A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental and significant concepts in this area. In the book, students discover that bacteria communicate, that DNA can be used for performing computations, how evolution solves optimization problems, that the way ants organize their nests can be applied to solve clustering problems, and what the human immune system can teach us about protecting computer networks. The authors discuss more biological examples such as these, along with the computational techniques developed from these scenarios. The text focuses on cellular automata, evolutionary computation, neural networks, and molecular computation. Each chapter explores the biological background, describes the computational techniques, gives examples of applications, discusses possible variants of the techniques, and includes exercises and solutions. The authors use the examples and exercises to illustrate key ideas and techniques. Clearly conveying the essence of the major computational approaches in the field, this book brings students to the point where they can either produce a working implementation of the techniques or effectively use one of the many available implementations. Moreover, the techniques discussed reflect fundamental principles that can be applied beyond bio-inspired computing. Supplementary material is available on Dr. Unger's website.

Introduction to Bio-Ontologies

Author : Peter N. Robinson,Sebastian Bauer
Publisher : CRC Press
Page : 514 pages
File Size : 52,9 Mb
Release : 2011-06-22
Category : Computers
ISBN : 9781439836668

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Introduction to Bio-Ontologies by Peter N. Robinson,Sebastian Bauer Pdf

Introduction to Bio-Ontologies explores the computational background of ontologies. Emphasizing computational and algorithmic issues surrounding bio-ontologies, this self-contained text helps readers understand ontological algorithms and their applications.The first part of the book defines ontology and bio-ontologies. It also explains the importan

Quantitative Biology

Author : Michael E. Wall
Publisher : CRC Press
Page : 406 pages
File Size : 40,7 Mb
Release : 2012-08-25
Category : Science
ISBN : 9781439827222

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Quantitative Biology by Michael E. Wall Pdf

Quantitative methods are revolutionizing modern molecular and cellular biology. Groundbreaking technical advances are fueling the rapid expansion in our ability to observe, as seen in multidisciplinary studies that integrate theory, computation, experimental assays, and the control of microenvironments. Integrating new experimental and theoretical methods, Quantitative Biology: From Molecular to Cellular Systems gives both new and established researchers a solid foundation for starting work in this field. The book is organized into three sections: Fundamental Concepts covers bold ideas that inspire novel approaches in modern quantitative biology. It offers perspectives on evolutionary dynamics, system design principles, chance and memory, and information processing in biology. Methods describes recently developed or improved techniques that are transforming biological research. It covers experimental methods for studying single-molecule biochemistry, small-angle scattering from biomolecules, subcellular localization of proteins, and single-cell behavior. It also describes theoretical methods for synthetic biology and modeling random variations among cells. Molecular and Cellular Systems focuses on specific biological systems where modern quantitative biology methods are making an impact. It incorporates case studies of biological systems for which new concepts or methods are increasing our understanding. Examples include protein kinase at the molecular level, the genetic switch of phage lambda at the regulatory system level, and Escherichia coli chemotaxis at the cellular level. In short, Quantitative Biology presents practical tools for the observation, modeling, design, and manipulation of biological systems from the molecular to the cellular levels.

Introduction to Proteins

Author : Amit Kessel,Nir Ben-Tal
Publisher : CRC Press
Page : 623 pages
File Size : 43,9 Mb
Release : 2010-12-17
Category : Medical
ISBN : 9781439810729

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Introduction to Proteins by Amit Kessel,Nir Ben-Tal Pdf

As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images throughout, Introduction to Proteins: Structure, Function, and Motion presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. The text incorporates various biochemical, physical, functional, and medical aspects. It covers different levels of protein structure, current methods for structure determination, energetics of protein structure, protein folding and folded state dynamics, and the functions of intrinsically unstructured proteins. The authors also clarify the structure–function relationship of proteins by presenting the principles of protein action in the form of guidelines. This comprehensive, color book uses numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. It refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online.

Computational Systems Biology of Cancer

Author : Emmanuel Barillot,Laurence Calzone,Philippe Hupe,Jean-Philippe Vert,Andrei Zinovyev
Publisher : CRC Press
Page : 461 pages
File Size : 51,8 Mb
Release : 2012-08-25
Category : Computers
ISBN : 9781439831458

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Computational Systems Biology of Cancer by Emmanuel Barillot,Laurence Calzone,Philippe Hupe,Jean-Philippe Vert,Andrei Zinovyev Pdf

The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models-integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencin

Biological Sequence Analysis Using the SeqAn C++ Library

Author : Andreas Gogol-Döring,Knut Reinert
Publisher : CRC Press
Page : 330 pages
File Size : 51,6 Mb
Release : 2009-11-11
Category : Computers
ISBN : 9781420076240

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Biological Sequence Analysis Using the SeqAn C++ Library by Andreas Gogol-Döring,Knut Reinert Pdf

An Easy-to-Use Research Tool for Algorithm Testing and DevelopmentBefore the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party monolithic software products. Addressing these conc

Cancer Systems Biology

Author : Edwin Wang
Publisher : CRC Press
Page : 456 pages
File Size : 41,5 Mb
Release : 2010-05-04
Category : Computers
ISBN : 1439811865

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Cancer Systems Biology by Edwin Wang Pdf

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discov

Handbook of Chemoinformatics Algorithms

Author : Jean-Loup Faulon,Andreas Bender
Publisher : CRC Press
Page : 454 pages
File Size : 51,6 Mb
Release : 2010-04-21
Category : Science
ISBN : 142008299X

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Handbook of Chemoinformatics Algorithms by Jean-Loup Faulon,Andreas Bender Pdf

Unlike in the related area of bioinformatics, few books currently exist that document the techniques, tools, and algorithms of chemoinformatics. Bringing together worldwide experts in the field, the Handbook of Chemoinformatics Algorithms provides an overview of the most common chemoinformatics algorithms in a single source.After a historical persp

Stochastic Modelling for Systems Biology

Author : Darren J. Wilkinson
Publisher : CRC Press
Page : 360 pages
File Size : 48,7 Mb
Release : 2011-11-09
Category : Mathematics
ISBN : 9781439837764

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Stochastic Modelling for Systems Biology by Darren J. Wilkinson Pdf

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Re-written to reflect this modern perspective, this second edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. Keeping with the spirit of the first edition, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. New in the Second Edition All examples have been updated to Systems Biology Markup Language Level 3 All code relating to simulation, analysis, and inference for stochastic kinetic models has been re-written and re-structured in a more modular way An ancillary website provides links, resources, errata, and up-to-date information on installation and use of the associated R package More background material on the theory of Markov processes and stochastic differential equations, providing more substance for mathematically inclined readers Discussion of some of the more advanced concepts relating to stochastic kinetic models, such as random time change representations, Kolmogorov equations, Fokker-Planck equations and the linear noise approximation Simple modelling of "extrinsic" and "intrinsic" noise An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional mathematical detail and computational methods that will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.

Dynamics of Biological Systems

Author : Michael Small
Publisher : CRC Press
Page : 286 pages
File Size : 46,9 Mb
Release : 2011-08-25
Category : Mathematics
ISBN : 9781439853368

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Dynamics of Biological Systems by Michael Small Pdf

From the spontaneous rapid firing of cortical neurons to the spatial diffusion of disease epidemics, biological systems exhibit rich dynamic behaviour over a vast range of time and space scales. Unifying many of these diverse phenomena, Dynamics of Biological Systems provides the computational and mathematical platform from which to understand the underlying processes of the phenomena. Through an extensive tour of various biological systems, the text introduces computational methods for simulating spatial diffusion processes in excitable media, such as the human heart, as well as mathematical tools for dealing with systems of nonlinear ordinary and partial differential equations, such as neuronal activation and disease diffusion. The mathematical models and computer simulations offer insight into the dynamics of temporal and spatial biological systems, including cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behaviour, the interaction of autonomous agents, and hierarchical and structured network topologies. Tools from complex systems and complex networks are also presented for dealing with real phenomenological systems. With exercises and projects in each chapter, this classroom-tested text shows students how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. MATLAB® implementations of algorithms and case studies are available on the author’s website.

Introduction to Computational Proteomics

Author : Golan Yona
Publisher : CRC Press
Page : 769 pages
File Size : 52,8 Mb
Release : 2010-12-09
Category : Mathematics
ISBN : 9781420010770

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Introduction to Computational Proteomics by Golan Yona Pdf

Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie