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Community Series In Epigenetics Of The Immune Component Of Inflammation Volume Ii Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Community Series In Epigenetics Of The Immune Component Of Inflammation Volume Ii book. This book definitely worth reading, it is an incredibly well-written.
Author : Guan-Jun Yang,Haitao Wang,Hai-Jing Zhong,Cheong-Meng Chong
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 50,6 Mb
Release : 2023-09-08
Category : Medical
ISBN : 9782832533741
Author : Simone Ferrero,Abdel Halim Harrath,Mainak Dutta
Publisher : Frontiers Media SA
Page : 115 pages
File Size : 41,6 Mb
Release : 2024-05-15
Category : Medical
ISBN : 9782832548943
*This Research Topic is a continuation of "Endometriosis: Pathogenesis, Diagnosis and Treatment"* Endometriosis is a benign gynecological condition that causes pain symptoms and infertility; these symptoms may significantly impair quality of life. It affects at least 4% of reproductive age women. Over the last 20 year several improvements have been made in the understanding of the molecular pathways involved in the pathogenesis of endometriosis which however remains to be fully elucidated. Transvaginal ultrasonography is the first line imaging technique used for the diagnosis of endometriosis, radiological imaging (such as magnetic resonance imaging and virtual colonoscopy) can be used for patients with suspicion of bowel or urinary tract endometriosis. Hormonal therapy is the first-line treatment of endometriosis related pain. First-line therapies are combined estroprogestins combinations and progestins. Second-line therapies include gonadotropin releasing hormone analogue and gonadotropin releasing hormone antagonist. Aromatase inhibitors have been proposed for the treatment of endometriosis but they are not approved for this use and they should be administered only in the setting of scientific research. Although, hormonal therapy decreases the intensity of pain symptoms, it is not curative, and symptoms usually recur after the discontinuation of treatment.
Author : Felipe Sierra,Ronald Kohanski
Publisher : Springer
Page : 622 pages
File Size : 51,8 Mb
Release : 2015-11-10
Category : Medical
ISBN : 9783319232461
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Author : Paul Emery
Publisher : Unknown
Page : 0 pages
File Size : 49,7 Mb
Release : 2005
Category : Rheumatoid arthritis
ISBN : 141602767X
This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
Author : José Luis García-Giménez
Publisher : Academic Press
Page : 696 pages
File Size : 41,6 Mb
Release : 2015-12-07
Category : Science
ISBN : 9780128019214
Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies
Author : Nathalie Bergeron,Patty W. Siri-Tarino,George A. Bray,Ronald M. Krauss
Publisher : CRC Press
Page : 624 pages
File Size : 45,7 Mb
Release : 2017-11-10
Category : Medical
ISBN : 9781351645720
Nutrition plays a key role in prevention of cardiovascular disease, the leading cause of death worldwide. Diet influences a broad spectrum of cardiometabolic risk factors, notably a cluster including excess adiposity, dyslipidemia, impaired glucose metabolism and high blood pressure. In the face of the rapidly increasing incidence of obesity and diabetes, maintaining cardiometabolic health through adoption of a healthy lifestyle is a top public health priority. In this book, Nutrition and Cardiometabolic Health, international experts present state-of-the-art scholarly reviews of dietary and lifestyle effects on metabolic systems associated with cardiovascular health and disease. It covers a broad range of topics including biological and behavioral processes regulating food intake; lifestyle and surgical approaches to weight loss; nutritional considerations for optimal cardiometabolic health across the lifespan; the relationship of macronutrients, whole foods and dietary patterns to diabetes and cardiovascular disease; and diet as a modulator of gene expression, epigenetics and the gut microbiome and the relationship of these traits to disorders of metabolism. This book provides its readers with an authoritative view of the present state of knowledge of dietary effects on cardiometabolic health and will be of interest to nutrition and healthcare professionals alike.
Author : Roberto de Paula do Nascimento,Ana Paula da Fonseca Machado,Alba Rodriguez-Nogales,Raquel Franco Leal,Carlos Augusto Real Martinez,Julio Galvez,Mario Roberto Maróstica Junior
Publisher : Elsevier
Page : 470 pages
File Size : 46,6 Mb
Release : 2023-03-17
Category : Science
ISBN : 9780323991124
Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation. Provides updated information on the pathogenesis of inflammatory bowel diseases and their pharmacological treatments and adverse effects Delivers the most up-to-date information regarding the molecular mechanisms of natural products in inflammatory bowel diseases Organizes the separation of natural products based on their characteristics, including lists of the main results of natural products in experiments conducted in vitro with animals, and in humans with IBDs
Author : Ane C.F. Nunes
Publisher : BoD – Books on Demand
Page : 249 pages
File Size : 48,8 Mb
Release : 2020-01-08
Category : Medical
ISBN : 9781789843576
Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental models, the chapters selected for this book bring to readers at different academic levels updated and practical data on inflammation. Find out what drives interdisciplinary medical research on inflammation and enjoy this informative collection.
Author : David Heber,Zhaoping Li,José Ordovas
Publisher : Elsevier
Page : 470 pages
File Size : 55,5 Mb
Release : 2023-10-20
Category : Technology & Engineering
ISBN : 9780443153167
Precision Nutrition: The Science and Promise of Personalized Nutrition and Health organizes and integrates information on the diverse special areas of scientific expertise involved in Precision Nutrition in order to inform health professionals and inspire researchers to advance this field while applying the general principles into health care and medical research now. Broken into three sections, this book addresses the fundamentals of precision nutrition, applications of precision nutrition in health and disease, and the future directions of precision nutrition. Nutrition scientists, geneticists, physicians, dietitians, postdoctoral fellows, and epidemiologists seeking to understand Precision Nutrition will benefit from this timely reference. . Applies precision nutrition to diet and lifestyle conditions, including heart disease, diabetes and cancer Identifies future aspects of precision nutrition utilizing AI, machine learning and superfast computers Outlines promising areas of research
Author : Dante Cicchetti
Publisher : John Wiley & Sons
Page : 1080 pages
File Size : 55,7 Mb
Release : 2016-02-29
Category : Psychology
ISBN : 9781118120910
The complete reference of biological bases for psychopathology at any age Developmental Psychopathology is a four-volume compendium of the most complete and current research on every aspect of the field. Volume Two: Developmental Neuroscience focuses on the biological basis of psychopathology at each life stage, from nutritional deficiencies to genetics to functional brain development to evolutionary perspectives and more. Now in its third edition, this comprehensive reference has been fully updated to better reflect the current state of the field, and detail the newest findings made possible by advances in technology and neuroscience. Contributions from expert researchers and clinicians provide insight into brain development, molecular genetics methods, neurogenics approaches to pathway mapping, structural neuroimaging, and much more, including targeted discussions of specific disorders. Advances in developmental psychopathology have burgeoned since the 2006 publication of the second edition, and keeping up on the latest findings in multiple avenues of investigation can be burdensome to the busy professional. This series solves the problem by collecting the information into one place, with a logical organization designed for easy reference. Consider evolutionary perspectives in developmental psychopathology Explore typical and atypical brain development across the life span Examine the latest findings on stress, schizophrenia, anxiety, and more Learn how genetics are related to psychopathology at different life stages The complexity of a field as diverse as developmental psychopathology deepens with each emerging theory, especially with consideration of the rapid pace of neuroscience advancement and genetic discovery. Developmental Psychopathology Volume Two: Developmental Neuroscience provides an invaluable resource by compiling the latest information into a cohesive, broad-reaching reference.
Author : Janice L Raymond,Kelly Morrow
Publisher : Elsevier Health Sciences
Page : 1227 pages
File Size : 41,9 Mb
Release : 2020-05-03
Category : Medical
ISBN : 9780323636568
NEW! Food-Nutrient Delivery: Planning the Diet with Cultural Competency chapter provides international nutrition guidelines and resources to assist you with multicultural meal planning. NEW! Clinical: Nutritional Genomics chapter features an author from the NIH’s Human Genome Project and introduces you to the latest research about CRISPR and epigenetics. NEW! MNT for Neurologic Disorders chapter features two new authors, including a speech therapist, and displays IDDSI guidelines and an appendix for dysphagia diets to help you carefully and consistently address the nutritional needs of these patients. NEW! Clinical: Water, Electrolytes, and Acid-Base Balance and Clinical: Biochemical, Physical, and Functional Assessment chapters are updated with the most relevant and evidence-based complementary and integrative approaches to expand your expertise in these clinical nutritional areas. NEW! MNT for Adverse Reactions to Food: Food Allergies and Intolerance chapter features completely revised guidelines and a new pathophysiology algorithm to ensure you are confident in your knowledge of how to prevent emergencies and what to do when emergencies do happen. NEW! Coverage of intermittent fasting, health at every size, and health disparities focuses on the latest nutrition trends to ensure you are well-versed in these topics. NEW! The Mediterranean Diet, Choline, and Biotin appendices display at-a-glance information to help you find quickly supplemental information. NEW! Directions boxes and Focus On boxes, as well as useful websites, resources, and key terms at the end of each chapter, help you find information quickly and easily.
Author : Dieter Kabelitz,Jaydeep Bhat
Publisher : Academic Press
Page : 386 pages
File Size : 45,8 Mb
Release : 2020-06-04
Category : Medical
ISBN : 9780128179659
Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications. Provides an overview of most important immune mechanisms, the current status of epigenetics, and how both of them are brought together Presents key principles of immune mechanisms in epigenetics, presenting current findings and key principles Features in-depth chapter contributions from a wide range of international researchers and specialists in immunology, translational medicine and epigenetics Merges two very large areas, covering the unique interrelatedness of epigenetics and immunology
Author : Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
Publisher : Elsevier
Page : 664 pages
File Size : 44,7 Mb
Release : 2014-06-23
Category : Science
ISBN : 9780124171343
Epigenetics in Psychiatry covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this potentially very important and useful area of psychiatry. The elucidation of basic principles of epigenetic biology points to the creation of more optimal and effective therapies for major classes of psychiatric disease. In this regard, epigenetic therapy, the use of drugs to correct epigenetic defects, may help in the pharmacotherapy of patients with these disorders. With time, such advances may eventually point to replacements for psychotropic drugs presently of symptomatic value and low efficacy. Moreover, there is evidence to suggest that other forms of treatment commonly used in the management of psychiatric disorders, like psychotherapy and electroconvulsive therapy, may also act by epigenetic mechanisms. Chapters review fascinating new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics through drug addiction Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and protein Catalyzes knowledge discovery in both basic epigenetic biology and clinical application as epigenetic targets for drug discovery
Author : Mauro Picardo,Alain Taïeb
Publisher : Springer
Page : 496 pages
File Size : 47,9 Mb
Release : 2019-07-23
Category : Medical
ISBN : 9783319629605
Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immune diathesis and skin events, which are easily detected using skin biopsies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was sufficient for the management of the patient with Vitiligo. This richly illustrated second edition reflects the constant international effort to share the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its aim still being to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.
Author : Heidi Makrinioti,Hideaki Morita,Eleni Nastouli,Tuomas Jartti
Publisher : Frontiers Media SA
Page : 114 pages
File Size : 55,6 Mb
Release : 2023-04-05
Category : Science
ISBN : 9782832518274