Complex Systems In Medicine

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Complex Systems in Medicine

Author : David C. Aron
Publisher : Springer Nature
Page : 255 pages
File Size : 55,6 Mb
Release : 2019-08-30
Category : Medical
ISBN : 9783030245931

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Complex Systems in Medicine by David C. Aron Pdf

This unique title explores complex systems in clinical medicine and the subsequent implementation of that knowledge into practice. Written conversationally and as a reflection on the journey of learning about complex systems, the book explores how knowledge of these systems can be applied to four key roles in academic medicine: clinical practice, education, research, and administration. Further, this title emphasizes how gaining an understanding of complex systems can greatly help a physician deal with the many challenges found in academic medicine. Unlike other books on complexity in medicine, which tend to focus on only one aspect of the management of patients, Complex Systems in Medicine deals with the multifaceted roles of a physician. The approach in this book is uniquely qualitative rather than mathematical, and is written to make it not only of interest to physicians, trainees, and allied health providers, but also to make it more accessible to a non-medical audience. The inclusion of personal anecdotes by the author provides concrete examples of the application of knowledge of complex systems in academic medicine. A first-of-its-kind contribution to the literature, Complex Systems in Medicine: A Hedgehog’s Tale of Complexity in Clinical Practice, Research, Education, and Management is not only a novel reference for medical professionals, it is an accessible tool for the non-medical audience hoping to learn more about complex systems and their direct relevance to medicine, a field that deals with the infinite variety of humans and their ills. It illustrates the consequences of the interactive elements of patient care that make medicine both a science and an art.

Network Medicine

Author : Joseph Loscalzo
Publisher : Harvard University Press
Page : 449 pages
File Size : 49,6 Mb
Release : 2017-02-01
Category : Medical
ISBN : 9780674436534

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Network Medicine by Joseph Loscalzo Pdf

Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.

Complex Systems and Population Health

Author : Yorghos Apostolopoulos,Kristen Hassmiller Lich,Michael K. Lemke
Publisher : Oxford University Press
Page : 336 pages
File Size : 44,8 Mb
Release : 2020-05-29
Category : Medical
ISBN : 9780190880767

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Complex Systems and Population Health by Yorghos Apostolopoulos,Kristen Hassmiller Lich,Michael K. Lemke Pdf

Currently, population health science is an integral part of global academic curricula. For over a century, the principles of the reductionist paradigm have guided population health curricula, training, research, and action. Researchers continue to draw upon these principles when theorizing, conceptualizing, designing studies, analyzing, and devising interventions to tackle complex population health problems. However, unresolved impasses in addressing pressing population health challenges have catalyzed calls for the integration of complex-systems-science-grounded approaches into population health science. Mounting evidence denotes that a complex systems paradigm can bring about dramatic, multipronged changes for education and training, and lead to innovative research, interventions, and policies. Despite the large and untapped promise of complex systems, the haphazard knowledge base from which academics, researchers, students, policymakers, and practitioners can draw has slowed their integration into the population health sciences. This volume fulfils this growing need by providing the knowledge base necessary to introduce a holistic complex systems paradigm in population health science. As such, it is the first comprehensive book in population health science that meaningfully integrates complex systems theory, methodology, modeling, computational simulation, and real-world applications, while incorporating current population health theoretical, methodological and analytical perspectives. It is intended as a programmatic primer across a broad spectrum of population health stakeholders: from university professors and graduate students, to researchers, policymakers, and practitioners.

Complex Systems Science in Biomedicine

Author : Thomas Deisboeck,J. Yasha Kresh
Publisher : Springer Science & Business Media
Page : 857 pages
File Size : 49,8 Mb
Release : 2007-06-13
Category : Medical
ISBN : 9780387335322

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Complex Systems Science in Biomedicine by Thomas Deisboeck,J. Yasha Kresh Pdf

Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Complex Systems in Medicine

Author : David C. Aron
Publisher : Unknown
Page : 253 pages
File Size : 49,6 Mb
Release : 2020
Category : Health services administration
ISBN : 3030245942

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Complex Systems in Medicine by David C. Aron Pdf

This unique title explores complex systems in clinical medicine and the subsequent implementation of that knowledge into practice. Written conversationally and as a reflection on the journey of learning about complex systems, the book explores how knowledge of these systems can be applied to four key roles in academic medicine: clinical practice, education, research, and administration. Further, this title emphasizes how gaining an understanding of complex systems can greatly help a physician deal with the many challenges found in academic medicine. Unlike other books on complexity in medicine, which tend to focus on only one aspect of the management of patients, Complex Systems in Medicine deals with the multifaceted roles of a physician. The approach in this book is uniquely qualitative rather than mathematical, and is written to make it not only of interest to physicians, trainees, and allied health providers, but also to make it more accessible to a non-medical audience. The inclusion of personal anecdotes by the author provides concrete examples of the application of knowledge of complex systems in academic medicine. A first-of-its-kind contribution to the literature, Complex Systems in Medicine: A Hedgehog's Tale of Complexity in Clinical Practice, Research, Education, and Management is not only a novel reference for medical professionals, it is an accessible tool for the non-medical audience hoping to learn more about complex systems and their direct relevance to medicine, a field that deals with the infinite variety of humans and their ills. It illustrates the consequences of the interactive elements of patient care that make medicine both a science and an art.

Handbook of Systems and Complexity in Health

Author : Joachim P Sturmberg,Carmel Martin
Publisher : Springer Science & Business Media
Page : 941 pages
File Size : 48,8 Mb
Release : 2013-01-09
Category : Medical
ISBN : 9781461449980

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Handbook of Systems and Complexity in Health by Joachim P Sturmberg,Carmel Martin Pdf

This book is an introduction to health care as a complex adaptive system, a system that feeds back on itself. The first section introduces systems and complexity theory from a science, historical, epistemological, and technical perspective, describing the principles and mathematics. Subsequent sections build on the health applications of systems science theory, from human physiology to medical decision making, population health and health services research. The aim of the book is to introduce and expand on important population health issues from a systems and complexity perspective, highlight current research developments and their implications for health care delivery, consider their ethical implications, and to suggest directions for and potential pitfalls in the future.

What Is a Complex System?

Author : James Ladyman,K. Wiesner
Publisher : Yale University Press
Page : 182 pages
File Size : 51,6 Mb
Release : 2020-08-05
Category : Computational complexity
ISBN : 9780300251104

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What Is a Complex System? by James Ladyman,K. Wiesner Pdf

A clear, concise introduction to the quickly growing field of complexity science that explains its conceptual and mathematical foundations What is a complex system? Although "complexity science" is used to understand phenomena as diverse as the behavior of honeybees, the economic markets, the human brain, and the climate, there is no agreement about its foundations. In this introduction for students, academics, and general readers, philosopher of science James Ladyman and physicist Karoline Wiesner develop an account of complexity that brings the different concepts and mathematical measures applied to complex systems into a single framework. They introduce the different features of complex systems, discuss different conceptions of complexity, and develop their own account. They explain why complexity science is so important in today's world.

Philosophy of Complex Systems

Author : Anonim
Publisher : Elsevier
Page : 952 pages
File Size : 48,6 Mb
Release : 2011-05-23
Category : Philosophy
ISBN : 0080931227

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Philosophy of Complex Systems by Anonim Pdf

The domain of nonlinear dynamical systems and its mathematical underpinnings has been developing exponentially for a century, the last 35 years seeing an outpouring of new ideas and applications and a concomitant confluence with ideas of complex systems and their applications from irreversible thermodynamics. A few examples are in meteorology, ecological dynamics, and social and economic dynamics. These new ideas have profound implications for our understanding and practice in domains involving complexity, predictability and determinism, equilibrium, control, planning, individuality, responsibility and so on. Our intention is to draw together in this volume, we believe for the first time, a comprehensive picture of the manifold philosophically interesting impacts of recent developments in understanding nonlinear systems and the unique aspects of their complexity. The book will focus specifically on the philosophical concepts, principles, judgments and problems distinctly raised by work in the domain of complex nonlinear dynamical systems, especially in recent years. -Comprehensive coverage of all main theories in the philosophy of Complex Systems -Clearly written expositions of fundamental ideas and concepts -Definitive discussions by leading researchers in the field -Summaries of leading-edge research in related fields are also included

Network Medicine

Author : Joseph Loscalzo,Albert-László Barabási,Edwin K. Silverman
Publisher : Harvard University Press
Page : 500 pages
File Size : 52,7 Mb
Release : 2017-02-01
Category : Medical
ISBN : 9780674545526

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Network Medicine by Joseph Loscalzo,Albert-László Barabási,Edwin K. Silverman Pdf

Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.

Introduction to the Theory of Complex Systems

Author : Stefan Thurner,R. A. Hanel,Peter Klimek
Publisher : Unknown
Page : 431 pages
File Size : 40,8 Mb
Release : 2018
Category : Social sciences
ISBN : 0191861065

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Introduction to the Theory of Complex Systems by Stefan Thurner,R. A. Hanel,Peter Klimek Pdf

Complex systems are everywhere. Ecosystems, financial markets, traffic, the economy, the internet and social media are complex systems. This textbook summarizes our understanding of complex systems and the methodological progress made over the past 20 years in a clear, structured, and comprehensive way.

Engineering a Learning Healthcare System

Author : National Academy of Engineering,Institute of Medicine
Publisher : National Academies Press
Page : 340 pages
File Size : 50,5 Mb
Release : 2011-06-14
Category : Medical
ISBN : 9780309224772

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Engineering a Learning Healthcare System by National Academy of Engineering,Institute of Medicine Pdf

Improving our nation's healthcare system is a challenge which, because of its scale and complexity, requires a creative approach and input from many different fields of expertise. Lessons from engineering have the potential to improve both the efficiency and quality of healthcare delivery. The fundamental notion of a high-performing healthcare system-one that increasingly is more effective, more efficient, safer, and higher quality-is rooted in continuous improvement principles that medicine shares with engineering. As part of its Learning Health System series of workshops, the Institute of Medicine's Roundtable on Value and Science-Driven Health Care and the National Academy of Engineering, hosted a workshop on lessons from systems and operations engineering that could be applied to health care. Building on previous work done in this area the workshop convened leading engineering practitioners, health professionals, and scholars to explore how the field might learn from and apply systems engineering principles in the design of a learning healthcare system. Engineering a Learning Healthcare System: A Look at the Future: Workshop Summary focuses on current major healthcare system challenges and what the field of engineering has to offer in the redesign of the system toward a learning healthcare system.

Crossing the Quality Chasm

Author : Institute of Medicine,Committee on Quality of Health Care in America
Publisher : National Academies Press
Page : 360 pages
File Size : 41,6 Mb
Release : 2001-08-19
Category : Medical
ISBN : 9780309072809

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Crossing the Quality Chasm by Institute of Medicine,Committee on Quality of Health Care in America Pdf

Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in America. Crossing the Quality Chasm makes an urgent call for fundamental change to close the quality gap. This book recommends a sweeping redesign of the American health care system and provides overarching principles for specific direction for policymakers, health care leaders, clinicians, regulators, purchasers, and others. In this comprehensive volume the committee offers: A set of performance expectations for the 21st century health care system. A set of 10 new rules to guide patient-clinician relationships. A suggested organizing framework to better align the incentives inherent in payment and accountability with improvements in quality. Key steps to promote evidence-based practice and strengthen clinical information systems. Analyzing health care organizations as complex systems, Crossing the Quality Chasm also documents the causes of the quality gap, identifies current practices that impede quality care, and explores how systems approaches can be used to implement change.

Complex Systems and Population Health

Author : Yorghos Apostolopoulos,Kristen Hassmiller Lich,Michael K. Lemke
Publisher : Oxford University Press, USA
Page : 337 pages
File Size : 54,9 Mb
Release : 2020-06-22
Category : Medical
ISBN : 9780190880743

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Complex Systems and Population Health by Yorghos Apostolopoulos,Kristen Hassmiller Lich,Michael K. Lemke Pdf

Complex Systems and Computation in Public Health Sciences is the first comprehensive book in population health science that meaningfully integrates complex systems theory, methodology, modeling, computational simulation, and real-world applications while incorporating current population health perspectives.

Translational Systems Medicine and Oral Disease

Author : Stephen Sonis,Alessandro Villa
Publisher : Academic Press
Page : 458 pages
File Size : 55,9 Mb
Release : 2019-09-14
Category : Medical
ISBN : 9780128137635

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Translational Systems Medicine and Oral Disease by Stephen Sonis,Alessandro Villa Pdf

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Complex Systems

Author : Rebecca Martinez
Publisher : Nova Publishers
Page : 0 pages
File Size : 40,9 Mb
Release : 2017
Category : Computational complexity
ISBN : 153610860X

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Complex Systems by Rebecca Martinez Pdf

This books provides new research on the theories and applications of complex systems. Chapter One reviews the process algebra approach to quantum electrodynamics. Chapter Two describes a specific aspect of complex systems and the fact that they may consist of established subsystems or components that originate from converging industries. Chapter Three examines the development of the generalised nonlinear Schrödinger equation of rotating cosmogonical body formation. Chapter Four analyses the application of neural network modeling in organising a hierarchical teaching system based on mentorship. The final chapter presents two methods to evaluate the collaborative potential of a network of 16 organisations and identifies measures to promote their coordination.