Computational Modeling And Simulation Examples In Bioengineering

Author : Nenad Filipovic
Publisher : John Wiley & Sons
Page : 386 pages
File Size : 45,6 Mb
Release : 2021-12-14
Category : Science
ISBN : 9781119563945

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Computational Modeling and Simulation Examples in Bioengineering by Nenad Filipovic Pdf

A systematic overview of the quickly developing field of bioengineering—with state-of-the-art modeling software! Computational Modeling and Simulation Examples in Bioengineering provides a comprehensive introduction to the emerging field of bioengineering. It provides the theoretical background necessary to simulating pathological conditions in the bones, muscles, cardiovascular tissue, and cancers, as well as lung and vertigo disease. The methodological approaches used for simulations include the finite element, dissipative particle dynamics, and lattice Boltzman. The text includes access to a state-of-the-art software package for simulating the theoretical problems. In this way, the book enhances the reader's learning capabilities in the field of biomedical engineering. The aim of this book is to provide concrete examples of applied modeling in biomedical engineering. Examples in a wide range of areas equip the reader with a foundation of knowledge regarding which problems can be modeled with which numerical methods. With more practical examples and more online software support than any competing text, this book organizes the field of computational bioengineering into an accessible and thorough introduction. Computational Modeling and Simulation Examples in Bioengineering: Includes a state-of-the-art software package enabling readers to engage in hands-on modeling of the examples in the book Provides a background on continuum and discrete modeling, along with equations and derivations for three key numerical methods Considers examples in the modeling of bones, skeletal muscles, cartilage, tissue engineering, blood flow, plaque, and more Explores stent deployment modeling as well as stent design and optimization techniques Generates different examples of fracture fixation with respect to the advantages in medical practice applications Computational Modeling and Simulation Examples in Bioengineering is an excellent textbook for students of bioengineering, as well as a support for basic and clinical research. Medical doctors and other clinical professionals will also benefit from this resource and guide to the latest modeling techniques.

Author : Miloš Kojić,Nenad Filipović,Boban Stojanović,Nikola Kojić
Publisher : John Wiley & Sons
Page : 484 pages
File Size : 45,8 Mb
Release : 2008-09-15
Category : Science
ISBN : 9780470751756

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Computer Modeling in Bioengineering by Miloš Kojić,Nenad Filipović,Boban Stojanović,Nikola Kojić Pdf

Bioengineering is a broad-based engineering discipline that applies engineering principles and design to challenges in human health and medicine, dealing with bio-molecular and molecular processes, product design, sustainability and analysis of biological systems. Applications that benefit from bioengineering include medical devices, diagnostic equipment and biocompatible materials, amongst others. Computer Modeling in Bioengineering offers a comprehensive reference for a large number of bioengineering topics, presenting important computer modeling problems and solutions for research and medical practice. Starting with basic theory and fundamentals, the book progresses to more advanced methods and applications, allowing the reader to become familiar with different topics to the desired extent. It includes unique and original topics alongside classical computational modeling methods, and each application is structured to explain the physiological background, phenomena that are to be modeled, the computational methods used in the model, and solutions of typical cases. The accompanying software contains over 80 examples, enabling the reader to study a topic using the theory and examples, then run the software to solve the same, or similar examples, varying the model parameters within a given range in order to investigate the problem at greater depth. Tutorials also guide the user in further exploring the modeled problem; these features promote easier learning and will help lecturers with presentations. Computer Modeling in Bioengineering includes computational methods for modelling bones, tissues, muscles, cardiovascular components, cartilage, cells and cancer nanotechnology as well as many other applications. It bridges the gap between engineering, biology and medicine, and will appeal not only to bioengineering students, lecturers and researchers, but also medical students and clinical researchers.

Author : Nenad Filipovic
Publisher : Springer Nature
Page : 175 pages
File Size : 47,6 Mb
Release : 2020-03-11
Category : Technology & Engineering
ISBN : 9783030436582

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Computational Bioengineering and Bioinformatics by Nenad Filipovic Pdf

This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts

Author : Riccardo Sacco,Giovanna Guidoboni,Aurelio Giancarlo Mauri
Publisher : Academic Press
Page : 854 pages
File Size : 45,6 Mb
Release : 2019-07-18
Category : Technology & Engineering
ISBN : 9780128125199

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A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences by Riccardo Sacco,Giovanna Guidoboni,Aurelio Giancarlo Mauri Pdf

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives Features examples, exercises, and MATLAB codes for further reader involvement Covers basic and advanced functional and computational techniques throughout the book

Author : Rogier P.van Wijk van Brievingh,Dietmar P.F. Möller,Xun Shen
Publisher : Springer Science & Business Media
Page : 533 pages
File Size : 52,8 Mb
Release : 2013-03-12
Category : Science
ISBN : 9781461391630

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Biomedical Modeling and Simulation on a PC by Rogier P.van Wijk van Brievingh,Dietmar P.F. Möller,Xun Shen Pdf

I have long had an interest in the life sciences, but have had few opportunities to indulge that interest in my professional activities. It has only been through simulation that those opportunities have arisen. Some of my most enjoyable classes were those I taught to students in the life sciences, where I attempted to show them the value of simulation to their discipline. That there is such a value cannot be questioned. Whether you are interested in population ecology, phar macokinetics, the cardiovascular system, or cell interaction, simulation can play a vital role in explaining the underlying processes and in enhancing our understanding of these processes. This book comprises an excellent collection of contributions, and clearly demonstrates the value of simulation in the particular areas of physiology and bioengineering. My main frustration when teaching these classes to people with little or no computer background was the lack of suitable simulation software. This di rectly inspired my own attempts at producing software usable by the computer novice. It is especially nice that software is available that enables readers to experience the examples in this book for themselves. I would like to congratulate and thank the editors, Rogier P. van Wijk van Brievingh and Dietmar P. P. Moller, for all of their excellent efforts. They should be proud of their achievement. This is the sixth volume in the Advances in Simulation series, and other volumes are in preparation.

Author : Willem van Meurs
Publisher : McGraw Hill Professional
Page : 224 pages
File Size : 43,9 Mb
Release : 2011-08-07
Category : Technology & Engineering
ISBN : 9780071714464

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Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology by Willem van Meurs Pdf

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

Author : Benoit Roux
Publisher : World Scientific
Page : 209 pages
File Size : 51,7 Mb
Release : 2021-08-23
Category : Computers
ISBN : 9789811232770

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Computational Modeling And Simulations Of Biomolecular Systems by Benoit Roux Pdf

This textbook originated from the course 'Simulation, Modeling, and Computations in Biophysics' that I have taught at the University of Chicago since 2011. The students typically came from a wide range of backgrounds, including biology, physics, chemistry, biochemistry, and mathematics, and the course was intentionally adapted for senior undergraduate students and graduate students. This is not a highly technical book dedicated to specialists. The objective is to provide a broad survey from the physical description of a complex molecular system at the most fundamental level, to the type of phenomenological models commonly used to represent the function of large biological macromolecular machines.The key conceptual elements serving as building blocks in the formulation of different levels of approximations are introduced along the way, aiming to clarify as much as possible how they are interrelated. The only assumption is a basic familiarity with simple mathematics (calculus and integrals, ordinary differential equations, matrix linear algebra, and Fourier-Laplace transforms).

Author : Socrates Dokos
Publisher : Springer
Page : 502 pages
File Size : 43,6 Mb
Release : 2017-03-08
Category : Technology & Engineering
ISBN : 9783642548017

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Modelling Organs, Tissues, Cells and Devices by Socrates Dokos Pdf

This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.

Author : Nenad Filipovic
Publisher : Academic Press
Page : 448 pages
File Size : 55,8 Mb
Release : 2019-10-09
Category : Science
ISBN : 9780128195840

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Computational Modeling in Bioengineering and Bioinformatics by Nenad Filipovic Pdf

Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary disciplines into an interactive and attractive forum. Chapters cover biomechanics and bioimaging, biomedical decision support system, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, biomedical image processing, analysis and visualization, high performance computing and sports bioengineering. The book's chapters are the result of many international projects in the area of bioengineering and bioinformatics done at the Research and Development Center for Bioengineering BioIRC and by the Faculty of Engineering at the University of Kragujevac, Serbia. Presents recent advances at the crossroads of biomedical engineering and bioinformatics, one of the hottest areas in biomedical and clinical research Discusses a wide range of leading-edge research topics, including biomechanics and bioimaging, biomedical decision support systems, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, amongst others Includes coverage of biomechanical, bioengineering and computational methods of treatment and diagnosis

Author : Guigen Zhang
Publisher : CRC Press
Page : 508 pages
File Size : 48,7 Mb
Release : 2015-04-01
Category : Medical
ISBN : 9781466517561

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Computational Bioengineering by Guigen Zhang Pdf

Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la

Author : Elmar Heinzle,Irving J. Dunn,John Ingham,Jiří E. Přenosil
Publisher : John Wiley & Sons
Page : 62 pages
File Size : 48,8 Mb
Release : 2021-07-06
Category : Science
ISBN : 9783527325245

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Biological Reaction Engineering by Elmar Heinzle,Irving J. Dunn,John Ingham,Jiří E. Přenosil Pdf

This practical book presents the modeling of dynamic biological engineering processes in a readily comprehensible manner, using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples illustrate almost every aspect of biological engineering science, with each one described in detail, including the model equations. The programs are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh computers. Madonna solves models comprising many ordinary differential equations using very simple programming, including arrays. It is so powerful that the model parameters may be defined as "sliders", which allow the effect of their change on the model behavior to be seen almost immediately. Data may be included for curve fitting, and sensitivity or multiple runs may be performed. The results can be viewed simultaneously on multiple-graph windows or by using overlays. The examples can be varied to fit any real situation, and the suggested exercises provide practical guidance. The extensive teaching experience of the authors is reflected in this well-balanced presentation, which is suitable for the teacher, student, biochemist or the engineer.

Author : R. P. van Wijk van Brievingh,Dietmar Möller
Publisher : Springer
Page : 517 pages
File Size : 52,5 Mb
Release : 1993-01-01
Category : Biotechnology
ISBN : 3540976507

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Biomedical Modeling and Simulation on a PC by R. P. van Wijk van Brievingh,Dietmar Möller Pdf

Author : Dimitrios I. Fotiadis,Antonis I. Sakellarios,Vassiliki T. Potsika
Publisher : John Wiley & Sons
Page : 404 pages
File Size : 50,7 Mb
Release : 2023-06-07
Category : Science
ISBN : 9781119517344

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Multiscale Modelling in Biomedical Engineering by Dimitrios I. Fotiadis,Antonis I. Sakellarios,Vassiliki T. Potsika Pdf

Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.

Author : M. Cerrolaza
Publisher : Imperial College Press
Page : 264 pages
File Size : 42,5 Mb
Release : 2004
Category : Science
ISBN : 1860945406

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Computational Bioengineering by M. Cerrolaza Pdf

This book is a significant contribution to the state of the art in the field of computational bioengineering from the need for a living human database to meshless methods in biomechanics, from computational mechanobiology to the evaluation of stresses in hip prosthesis replacement, from lattice Boltzmann methods for analyzing blood flow to the analysis of fluid movement in long bones, among other interesting topics treated herein. Well-known international experts in bioengineering have contributed to the book, giving it a unique style and cutting-edge material for graduate students, academic researchers and design bioengineers, as well as those interested in getting a better understanding of such complex and fascinating human and living processes.

Author : Masao Tanaka,Shigeo Wada,Masanori Nakamura
Publisher : Springer Science & Business Media
Page : 207 pages
File Size : 45,5 Mb
Release : 2012-06-16
Category : Technology & Engineering
ISBN : 9784431540724

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Computational Biomechanics by Masao Tanaka,Shigeo Wada,Masanori Nakamura Pdf

Rapid developments have taken place in biological/biomedical measurement and imaging technologies as well as in computer analysis and information technologies. The increase in data obtained with such technologies invites the reader into a virtual world that represents realistic biological tissue or organ structures in digital form and allows for simulation and what is called “in silico medicine.” This volume is the third in a textbook series and covers both the basics of continuum mechanics of biosolids and biofluids and the theoretical core of computational methods for continuum mechanics analyses. Several biomechanics problems are provided for better understanding of computational modeling and analysis. Topics include the mechanics of solid and fluid bodies, fundamental characteristics of biosolids and biofluids, computational methods in biomechanics analysis/simulation, practical problems in orthopedic biomechanics, dental biomechanics, ophthalmic biomechanics, cardiovascular biomechanics, hemodynamics, cell mechanics, and model-, rule-, and image-based methods in computational biomechanics analysis and simulation. The book is an excellent resource for graduate school-level engineering students and young researchers in bioengineering and biomedicine.