Modelling Organs Tissues Cells And Devices

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Modelling Organs, Tissues, Cells and Devices

Socrates Dokos
Modelling Organs Tissues Cells and Devices Book PDF

Author : Socrates Dokos
Publisher : Springer
Page : 502 pages
File Size : 50,6 Mb
Release : 2017-03-08
Category : Technology & Engineering
ISBN : 9783642548017

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Modelling Organs, Tissues, Cells and Devices by Socrates Dokos Pdf

This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.

Structure-Based Mechanics of Tissues and Organs

Ghassan S. Kassab,Michael S. Sacks
Structure Based Mechanics of Tissues and Organs Book PDF

Author : Ghassan S. Kassab,Michael S. Sacks
Publisher : Springer
Page : 469 pages
File Size : 47,9 Mb
Release : 2016-01-28
Category : Science
ISBN : 9781489976307

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Structure-Based Mechanics of Tissues and Organs by Ghassan S. Kassab,Michael S. Sacks Pdf

This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, not only to avoid ambiguities in material characterization, but also to offer insights into the function, structure, and mechanics of tissue components. A statement of future directions of the field is also given, including how advancements, such as state-of-the-art computational modeling and optical measurements of tissue/cells structures, are taking structure-based modeling to the next level. This book also: Provides a comprehensive view of tissue modeling across multiple systems Broadens readers’ understanding of state-of-the-art computational modeling and optical measurements of tissue/cells structures Describes in detail fiber scale properties such as orientation and crimp

Biomechanics of Living Organs

Yohan Payan,Jacques Ohayon
Biomechanics of Living Organs Book PDF

Author : Yohan Payan,Jacques Ohayon
Publisher : World Bank Publications
Page : 44 pages
File Size : 50,8 Mb
Release : 2017-06-09
Category : Medical
ISBN : 9780128040607

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Biomechanics of Living Organs by Yohan Payan,Jacques Ohayon Pdf

Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions

Principles and Technologies for Electromagnetic Energy Based Therapies

Punit Prakash,Govindarajan Srimathveeravalli
Principles and Technologies for Electromagnetic Energy Based Therapies Book PDF

Author : Punit Prakash,Govindarajan Srimathveeravalli
Publisher : Academic Press
Page : 424 pages
File Size : 41,7 Mb
Release : 2021-12-02
Category : Technology & Engineering
ISBN : 9780128206119

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Principles and Technologies for Electromagnetic Energy Based Therapies by Punit Prakash,Govindarajan Srimathveeravalli Pdf

Principles and Technologies for Electromagnetic Energy Based Therapies covers the theoretical foundations of electromagnetic-energy based therapies, principles for design of practical devices and systems, techniques for in vitro and in vivo testing of devices, and clinical application examples of contemporary therapies employing non-ionizing electromagnetic energy. The book provides in-depth coverage of: pulsed electric fields, radiofrequency heating systems, tumor treating fields, and microwave heating technology. Devices and systems for electrical stimulation of neural and cardiac issue are covered as well. Lastly, the book describes and discusses issues that are relevant to engineers who develop and translate these technologies to clinical applications. Readers can access information on incorporation of preclinical testing, clinical studies and IP protection in this book, along with in-depth technical background for engineers on electromagnetic phenomena within the human body and selected therapies. It covers both engineering and biological/medical materials and gives a full perspective on electromagnetics therapies. Unique features include content on tumor treating fields and the development and translation of biomedical devices. Provides in-depth technical background on electromagnetic energy-based therapies, along with real world examples on how to design devices and systems for delivering electromagnetic energy-based therapies Includes guidance on issues that are relevant for translating the technology to the market, such as intellectual property, regulatory issues, and preclinical testing Companion site includes COMSOL models, MATLAB code, and lab protocols

Mechanical Properties of Human Tissues

Arnab Chanda,Gurpreet Singh
Mechanical Properties of Human Tissues Book PDF

Author : Arnab Chanda,Gurpreet Singh
Publisher : Springer
Page : 0 pages
File Size : 41,6 Mb
Release : 2023-09-11
Category : Science
ISBN : 9819922240

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Mechanical Properties of Human Tissues by Arnab Chanda,Gurpreet Singh Pdf

This monograph brings forth biomechanical research methods and outcomes on human tissue experiments such as those of the brain and the heart under a single umbrella. Different mechanical characterization techniques employed in human tissue property estimation are presented in detail. The contents also focus on a hyperelastic constitutive model (e.g., Mooney-Rivlin, Ogden) for both isotropic and anisotropic tissue characterization. It also discusses energy dissipation in soft tissues and associated viscoelasticity. Human tissues, including skin, muscles, connective tissues, and tissues in all functional organs are listed and their mechanical properties are presented in detail. These tissue properties are indispensable for computational modeling of biological systems, validation of biomechanical tissue testing, medical simulation through development of artificial phantoms and surrogates, and testing of medical devices and interventions. This book will serve as a key reference for research in tissue engineering & biomedical engineering, medical simulation, biomechanics, finite element modeling of biological systems, biomaterials, biotechnology, implant and medical device development, and healthcare wearables.

IX Latin American Congress on Biomedical Engineering and XXVIII Brazilian Congress on Biomedical Engineering

Jefferson Luiz Brum Marques,Cesar Ramos Rodrigues,Daniela Ota Hisayasu Suzuki,José Marino Neto,Renato García Ojeda
IX Latin American Congress on Biomedical Engineering and XXVIII Brazilian Congress on Biomedical Engineering Book PDF

Author : Jefferson Luiz Brum Marques,Cesar Ramos Rodrigues,Daniela Ota Hisayasu Suzuki,José Marino Neto,Renato García Ojeda
Publisher : Springer Nature
Page : 623 pages
File Size : 42,9 Mb
Release : 2023-12-16
Category : Technology & Engineering
ISBN : 9783031494017

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IX Latin American Congress on Biomedical Engineering and XXVIII Brazilian Congress on Biomedical Engineering by Jefferson Luiz Brum Marques,Cesar Ramos Rodrigues,Daniela Ota Hisayasu Suzuki,José Marino Neto,Renato García Ojeda Pdf

This book reports on the latest research and developments in Biomedical Engineering, with a special emphasis on topics of interest and findings achieved in Latin America. This first volume of a 4-volume set covers advances in modeling and simulation of biological and biomedical systems, mechanical characterization, and biological evaluation of biomaterials for medical applications, including tissues regeneration. It also covers some related special topics, such as advanced methodologies for agricultural and food production and public health management. Throughout the book, a special emphasis is given to low-cost technologies and to their development for and applications in clinical settings. Based on the IX Latin American Conference on Biomedical Engineering (CLAIB 2022) and the XXVIII Brazilian Congress on Biomedical Engineering (CBEB 2022), held jointly, and virtually on October 24-28, 2022, from Florianópolis, Brazil, this book provides researchers and professionals in the biomedical engineering field with extensive information on new technologies and current challenges for their clinical applications. .

3D Bioprinting

Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh
3D Bioprinting Book PDF

Author : Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh
Publisher : Springer
Page : 114 pages
File Size : 41,7 Mb
Release : 2020-12-16
Category : Medical
ISBN : 3030322246

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3D Bioprinting by Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh Pdf

This text advances fundamental knowledge in modeling in vitro tissues/organs as an alternative to 2D cell culture and animal testing. Prior to engineering in vitro tissues/organs,the descriptions of prerequisites (from pre-processing to post-processing) in modeling in vitro tissues/organs are discussed. The most prevalent technologies that have been widely used for establishing the in vitro tissue/organ models are also described, including transwell, cell spheroids/sheets, organoids, and microfluidic-based chips. In particular, the authors focus on 3D bioprinting in vitro tissue/organ models using tissue-specific bioinks. Several representative bioprinting methods and conventional bioinks are introduced. As a bioink source, decellularized extracellular matrix (dECM) are importantly covered, including decellularization methods, evaluation methods for demonstrating successful decellularization, and material safety. Taken together, the authors delineate various application examples of 3D bioprinted in vitro tissue/organ models especially using dECM bioinks.

Encyclopedia of Bioinformatics and Computational Biology

Anonim
Encyclopedia of Bioinformatics and Computational Biology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 47,8 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Biomaterials, Artificial Organs and Tissue Engineering

L. L. Hench,Julian R. Jones
Biomaterials Artificial Organs and Tissue Engineering Book PDF

Author : L. L. Hench,Julian R. Jones
Publisher : Woodhead Pub Limited
Page : 284 pages
File Size : 43,7 Mb
Release : 2005
Category : Medical
ISBN : 185573737X

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Biomaterials, Artificial Organs and Tissue Engineering by L. L. Hench,Julian R. Jones Pdf

This textbook and collection of illustrated CD lectures summarizes how maintaining quality of life in an aging population is being achieved by the development of specialty biomaterials, devices, artificial organs, and in vitro growth of human cells as tissue engineered constructs. Following an introduction to living and man-made materials, the book discusses clinical applications of biomaterials and devices, summarizes the bioengineering principles and materials used in artificial organs, and presents the concepts and applications of tissue engineering. It concludes with the complex socio-economic factors involved in technology-based healthcare. Each chapter is supplemented with illustrated PowerPoint lectures and study questions on a CD.

Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models

J. Miguel Oliveira,Rui L. Reis
Biomaterials and Microfluidics Based Tissue Engineered 3D Models Book PDF

Author : J. Miguel Oliveira,Rui L. Reis
Publisher : Springer Nature
Page : 176 pages
File Size : 52,9 Mb
Release : 2020-04-13
Category : Medical
ISBN : 9783030365882

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Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models by J. Miguel Oliveira,Rui L. Reis Pdf

This contributed volume reviews the latest advances on relevant 3D tissue engineered in vitro models of disease making use of biomaterials and microfluidics. The main focus of this book is on advanced biomaterials and microfluidics technologies that have been used in in vitro mimetic 3D models of human diseases and show great promise in revolutionizing personalized medicine. Readers will discover important topics involving biomaterials and microfluidics design, advanced processing techniques, and development and validation of organ- and body-on-a-chip models for bone, liver, and cancer research. An in depth discussion of microfabrication methods for microfluidics development is also provided. This work is edited by two truly multidisciplinary scientists and includes important contributions from well-known experts in their fields. The work is written for both early stage and experienced researchers, and well-established scientists enrolled in the fields of biomaterials, microfluidics, and tissue engineering, and is especially suited to those who wish to become acquainted with the principles and latest developments of in vitro models of diseases, such as professionals working in pharma, medicine, and engineering.

Microfluidics and Multi Organs on Chip

P. V. Mohanan
Microfluidics and Multi Organs on Chip Book PDF

Author : P. V. Mohanan
Publisher : Springer Nature
Page : 712 pages
File Size : 42,8 Mb
Release : 2022-07-11
Category : Medical
ISBN : 9789811913792

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Microfluidics and Multi Organs on Chip by P. V. Mohanan Pdf

This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.

Human Organs-on-a-Chip

Javier Ramón-Azcón,Artur Rydosz
Human Organs on a Chip Book PDF

Author : Javier Ramón-Azcón,Artur Rydosz
Publisher : Elsevier
Page : 380 pages
File Size : 51,9 Mb
Release : 2023-11-15
Category : Science
ISBN : 9780443153853

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Human Organs-on-a-Chip by Javier Ramón-Azcón,Artur Rydosz Pdf

Human Organs-on-Chip: Novel Organ-on-a-Chip Techniques in Medicine paves the way for novel approaches that push forward in-vitro and in-vivo studies and fills a gap between laboratory and clinical use. These experienced authors share the knowledge they’ve developed with over a decade of experience and research with organ-on-chips and multi-organ-on-chips. This book collects all of the developments in the field and sheds new light on possibilities to develop human on-chip measurement methods with the utilization of currently available measurement techniques including both invasive and non-invasive tests. Human Organs-on-Chip: Novel Organ-on-a-Chip Techniques in Medicine serves as a starting point for young researchers who are beginning their scientific journeys. Provides an overview of the progress suborgan-on-chips development has made in recent years Introduces the fundamentals needed to understand lab-on-chip ideas with references and in-depth explanations Presents commercial achievements obtained and future perspectives

Kinetic Modelling in Systems Biology

Oleg Demin,Igor Goryanin
Kinetic Modelling in Systems Biology Book PDF

Author : Oleg Demin,Igor Goryanin
Publisher : CRC Press
Page : 360 pages
File Size : 54,9 Mb
Release : 2008-10-24
Category : Mathematics
ISBN : 9781420011661

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Kinetic Modelling in Systems Biology by Oleg Demin,Igor Goryanin Pdf

With more and more interest in how components of biological systems interact, it is important to understand the various aspects of systems biology. Kinetic Modelling in Systems Biology focuses on one of the main pillars in the future development of systems biology. It explores both the methods and applications of kinetic modeling in this emerging f

Biofabrication and 3D Tissue Modeling

Dong-Woo Cho
Biofabrication and 3D Tissue Modeling Book PDF

Author : Dong-Woo Cho
Publisher : Royal Society of Chemistry
Page : 369 pages
File Size : 47,7 Mb
Release : 2019-01-02
Category : Technology & Engineering
ISBN : 9781788016643

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Biofabrication and 3D Tissue Modeling by Dong-Woo Cho Pdf

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.

Side Effects of Drugs Annual

Sidhartha D. Ray
Side Effects of Drugs Annual Book PDF

Author : Sidhartha D. Ray
Publisher : Elsevier
Page : 700 pages
File Size : 40,7 Mb
Release : 2019-11-06
Category : Medical
ISBN : 9780128171646

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Side Effects of Drugs Annual by Sidhartha D. Ray Pdf

Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 41, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more. Provides a critical yearly survey of the new data and trends regarding the side effects of drugs Authored and reviewed by worldwide pioneers in the clinical and practice sciences Presents an essential clinical guide on the side effects of drugs for practitioners and healthcare professionals alike