Download Full eBooks in PDF
Control And Manipulation Of Calcium Movement Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Control And Manipulation Of Calcium Movement book. This book definitely worth reading, it is an incredibly well-written.
Author : James R. Parratt
Publisher : Unknown
Page : 408 pages
File Size : 44,9 Mb
Release : 2024-06-30
Category : Electronic
ISBN : 078377219X
Author : Biological Council. Co-ordinating Committee for Symposia on Drug Action
Publisher : Raven Press (ID)
Page : 416 pages
File Size : 45,9 Mb
Release : 1985
Category : Medical
ISBN : UCAL:B4494614
Author : Biological Council. Co-ordinating Committee for Symposia on Drug Action
Publisher : Raven Press (ID)
Page : 420 pages
File Size : 44,6 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015009515910
Author : Gary Fiskum
Publisher : Springer Science & Business Media
Page : 613 pages
File Size : 55,7 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9781468455984
A widespread appreciation for the role that calcium plays in cell physiology and patho physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D. C. The participants in this unique meeting rep resented diverse fields of basic and clinical research, such as molecular physiology, oncology, molecular genetics, cardiology, bioenergetics, pathology, and endocrinology. The content of the proceedings of the symposium represents work in these and other areas of biomedical research. Organization of the book is aimed at striking a balance between the biochemistry 2 and physiology of normal cell Ca + metabolism and the pathological consequences of al 2 terations in cell Ca + homeostasis. The first section of the book is devoted to the transport mechanisms responsible for 2 2 regulating intracellular Ca + and the pharmacological modalities for controlling cell Ca + . Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels. The second section covers the exciting relationships between phosphoinositide metab 2 olism, signal transduction, and cell Ca + metabolism. This section begins with an eloquent overview by Professor Michael Berridge, who was the keynote speaker at the symposium and the recipient of the scientific merit award.
Author : Robert E. Garfield,Thomas N. Tabb
Publisher : Routledge
Page : 454 pages
File Size : 43,8 Mb
Release : 2019-06-12
Category : Medical
ISBN : 9780429523878
Published in 1994: The Editors have outlines many advances in the field of uterine physiology in hopes of furthering the science.
Author : Hans Michael Piper,Gerrit Isenberg
Publisher : CRC Press
Page : 332 pages
File Size : 45,8 Mb
Release : 2019-07-17
Category : Medical
ISBN : 9781000694383
First published in 1989, written with contributions from experts who have critically evaluated the state of the art and the prospects of isolated adults cardiac myocytes in cardiological research, this two-volume publication summarizes the current knowledge of this technology. The methodology, structure, and metabolism of cardiomyocytes are presented, along with metabolism and cation homeostasis and energy metabolism and hypoxic injury. Additionally, cell isolation and culture and the structure and biochemistry of the sarcolemma is explained. Electrophysiology and contractile function with ionic currents and membrane channels is discussed. Also, the electro-physiological effects of transmitters and hormones are presented, with excitation-contraction coupling and the use of cardiomyocytes in drug design and research explained.
Author : Dipak K. Das
Publisher : CRC Press
Page : 534 pages
File Size : 52,6 Mb
Release : 1992-10-16
Category : Medical
ISBN : 0849345553
Pathophysiology of Reperfusion Injury presents the first integrated summary of the important areas of reperfusion injury. By covering reperfusion injury in the heart, lungs, liver, kidneys, and small bowel, the book demonstrates the interrelationships of these various aspects and concludes that they are all part of a natural and integrated whole. The leading investigators in the field address the potential biochemical, cellular, and molecular mechanisms of reperfusion injury, which will benefit all researchers working in this field.
Author : R.J. Pollitt,R. Angus Harkness,G.M. Addison
Publisher : Springer Science & Business Media
Page : 279 pages
File Size : 45,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9789400912595
captured for the published proceedings. Nevertheless, the two Supplements to this Journal (also available together as a hard-backed book) do, over the years, embrace many of the major aspects of the study of inborn errors of metabolism and can, particularly with the Short Communications section, be used as a way into the literature on specific new topics. We hope that with judicious selection of material these supplements will continue to provide, as did the Society's earlier annual publications, a balanced record of the present state of the subject in all its facets, a record of interest to those working in allied fields as well as to the specialist. R. J. Pollitt G. M. Addison R. A. Harkness The papers listed below were also presented at the meeting. Scripts were not available by the time of publication. 1. Tangier disease and related disorders of apolipoprotein Al. G. Assmann, Munster. 2. Contribution to Ethics Symposium by M. E. Pembrey, London.
Author : Beverly H. Lorell,William Grossman
Publisher : Springer Science & Business Media
Page : 342 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461525943
Numerous studies have documented the importance of diastolic dysfunction in heart disease. Now, providing cardiologists with the most current information available on the subject, the editors have pulled together contributions from an impressive array of top researchers and compiled them into one comprehensive, carefully edited source, Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease. This brand new Second Edition, based on a recent meeting, includes such topics as: molecular biology of relaxation; consequences of altered gene expression; impaired relaxation in experimental models (ischemia and hypoxia, and hypertrophy and failure); diastolic dysfunction in the diseased human heart. Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease, the successor to the editors' bestselling work on the same subject, published in 1987 - belongs on the shelf of every practising cardiologist. It will also be an invaluable addition to the library of scientists researching the effects of diastole on heart function.
Author : George Poste,Stanley T. Crooke
Publisher : Springer Science & Business Media
Page : 441 pages
File Size : 51,6 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468450620
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1736 pages
File Size : 47,8 Mb
Release : 2024-06-30
Category : Medicine
ISBN : STANFORD:36105009872693
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1728 pages
File Size : 44,7 Mb
Release : 1985
Category : Medicine
ISBN : MINN:31951M013754299
Author : Richard Nathan
Publisher : Elsevier
Page : 341 pages
File Size : 42,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323155182
Cardiac Muscle: The Regulation of Excitation and Contraction is a 12-chapter text that covers the research studies on characterizing the ionic and molecular mechanisms that regulate excitation and contraction of cardiac muscle. This book describes first the ionic currents underlying diastolic depolarization and pacing of the heart. The discussions then shift to the mechanisms of action of calcium-channel antagonists; the regulation of calcium influx by indigenous factors, such as voltage- or calcium-mediated inactivation; the identification of fixed negative charges on the surface of the sarcolemma; and the regulation of gating and permeability of ion channels by these charges. These topics are followed by examining the molecular and ionic mechanisms that underlie the electrophysiologic actions of adrenergic and cholinergic neurotransmitters and peptide hormones. This text further explores the theoretical and experimental studies of the sodium-calcium exchange process, its stoichiometry, and how the exchanger might contribute to current flow during or after the action potential. Other chapters consider the mechanism of twitch and tonic tension regulation by cardiac glycosides and intracellular sodium and how toxic concentrations induce cardiac arrhythmias. A chapter highlights the identification of sarcolemmal binding sites for calcium, the likelihood that such binding or the release of calcium from the sarcoplasmic reticulum plays a role in the regulation of contraction and the release of calcium from the sarcoplasmic reticulum. The remaining chapters deal with the structural similarities among calcium-binding proteins of the contractile apparatus and the calcium channel, and the regulation of contraction by calcium-binding proteins. Physiologists, pathophysiologists, clinicians, researchers, and students who are interested in heart’s function will find this book invaluable.
Author : Naranjan S. Dhalla,Ian R. Innes,Robert E. Beamish
Publisher : Springer Science & Business Media
Page : 352 pages
File Size : 50,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461320555
Whenever the coronary flow is inadequate to provide enough oxygen to meet the energy demands of the tissue, the heart becomes ischemic. Manifestations of myocardial ischemia include depression in contractile activity, changes in metabolic pattern, abnormalities in ultrastructure, and alterations in membrane potential. Ischemic changes during the early phase are reversible but as the period of ischemia is extended, the injury becomes irreversible. The transition from reversible to irreversible ischemic injury is usually associated with some membrane defects. It is worthwhile to consider that the irreversible damage to the ischemic myocardium occurs when the sarcolemmal membrane is altered in suoh a way that it would promote 2 a net gain of ca + in the cardiac cell upon reinstitution of blood flow. Suoh a lesion could result when mechanisms for the entry as well as removal 2 of ca + from the myocardial oell become defective. In this regard, 2 depression of the sarcolemmal ca + pump would favour the oocurrenoe of 2 intracellular ca + overload. Furthermore, inhibition of the Na+-K+ pump would lead to elevation of myoplasmic Na+ which oould then increase the 2 2 intracellular concentration of ca + through the sarcolemmal Na+-ca + exchange mechanism. In faot recent studies have revealed an inhibition of 2 the sarcolemmal Na+-ca + exchange mechanism in the ischemic heart and this 2 change could also contribute towards the occurrence of intracellular ca + 2 overload.
Author : Angelo Azzi,Zdenek Drahota,Sergio Papa
Publisher : Springer Science & Business Media
Page : 437 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642744150
Biological membranes are often effected by diseases. Molecular events leading to or arising from pathological changes in the course of different diseases are as yet not clearly understood. This competent study by leading experts covers changes of the cellular environment, membranes and the metabolic functions during tissue growth and differentiation as well as aspects of abnormal organelle function in lysosomal storage diseases, peroxisomal and mitochondrial disorders, enzyme defects and regulatory defects of receptors due to oncogenes.
