Cord Of Blood

Author : Niranjan Bhattacharya,Phillip Stubblefield
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 52,8 Mb
Release : 2009-04-21
Category : Medical
ISBN : 9781848001671

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Frontiers of Cord Blood Science by Niranjan Bhattacharya,Phillip Stubblefield Pdf

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

Author : Yuping Wang
Publisher : Biota Publishing
Page : 126 pages
File Size : 55,8 Mb
Release : 2017-06-23
Category : Medical
ISBN : 9781615047512

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Vascular Biology of the Placenta by Yuping Wang Pdf

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Author : Karen Ballen
Publisher : Springer
Page : 290 pages
File Size : 51,8 Mb
Release : 2014-08-12
Category : Science
ISBN : 9783319064444

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Umbilical Cord Blood Banking and Transplantation by Karen Ballen Pdf

This comprehensive volume discusses the current scope of umbilical cord blood transplantation (UCBT), including recent controversies and future developments for improving clinical outcomes. Its twenty chapters introduce new applications in regenerative medicine and discuss the latest scientific, regulatory, clinical and investigational aspects of cord blood banking. Physicians from around the world provide a global collaboration which explores strategies for umbilical cord blood expansion, homing, unit selection, and combining of graft sources to improve patient outcomes. Umbilical Cord Blood Banking and Transplantation also reviews advances in pediatric UCBT for hematologic and non-hematologic disorders as well as immune recovery, which is critical to preventing infection. Finally, it compares UCBT with other graft sources in an attempt to understand the optimal graft source for the individual patient. UCBT is an important option for many patients who need a transplant but do not have a family donor or a matched unrelated donor. The collective and timely knowledge presented here is essential reading for any regenerative medicine investigator, cord blood banker, transplant laboratory scientist or clinical physician interested in improving and expanding the applications of umbilical cord blood.

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Establishing a National Cord Blood Stem Cell Bank Program
Publisher : National Academies Press
Page : 335 pages
File Size : 46,9 Mb
Release : 2005-11-26
Category : Medical
ISBN : 9780309095860

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Cord Blood by Institute of Medicine,Board on Health Sciences Policy,Committee on Establishing a National Cord Blood Stem Cell Bank Program Pdf

With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines: The role of cord blood in stem cell transplantation The current status of blood banks already in existence The optimal structure for the cord blood program The current use and utility of cord blood for stem cell transplants The best way to advance the use of cord blood units and make them available for research Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders.

Author : Lisandra Vanostrand
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 52,7 Mb
Release : 2013
Category : Blood banks
ISBN : 1626180725

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Cord Blood by Lisandra Vanostrand Pdf

In this book, the authors discuss cord blood banks and banking, the ethical issues involved and the risks and benefits. Topics include the virological risks and benefits of cord blood banking; mesenchymal stem cells and their role in regenerative medicine applications; osteogenic potential of human umbilical cord-derived mesenchymal stromal cells; public versus private cord blood banking; CCR5 deficient cord blood as a means of treatment for HIV-1 infection; and the therapeutic use of umbilical cord blood.

Author : American College of Obstetricians and Gy
Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
Page : 0 pages
File Size : 48,7 Mb
Release : 2014
Category : Medical
ISBN : 1934984302

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Neonatal Encephalopathy and Neurologic Outcome by American College of Obstetricians and Gy Pdf

Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Author : Michelle Kenyon,Aleksandra Babic
Publisher : Springer
Page : 311 pages
File Size : 51,7 Mb
Release : 2018-03-14
Category : Medical
ISBN : 9783319500263

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The European Blood and Marrow Transplantation Textbook for Nurses by Michelle Kenyon,Aleksandra Babic Pdf

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Author : Axel R. Zander,Wolfram Ostertag,Boris V. Afanasiev,Frank Grosveld
Publisher : Springer Science & Business Media
Page : 534 pages
File Size : 43,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642611223

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Gene Technology by Axel R. Zander,Wolfram Ostertag,Boris V. Afanasiev,Frank Grosveld Pdf

The 11 th meeting in "Modern Trends in Human Leukemia" took place from June 19 to 21, 1994 in Wilsede in the middle of the Liineburger Heide, South of Hamburg. Interwoven with the Leukemia program was the Nato-sponsored Symposium of the ASI-Series "Gene Technology in Analysis of Malignant and Inherited Human Diseases Related to Development" . The Wilsede meeting was continued on a ship of the Neva leading through lake Ladoga and lake Onega. The topics of both meetings included discussion on recent progress isolation and development of hematopoietic stem cells, genes crucial for development and diseases, methods of gene transfer, application of gene transfer; oncogenes and anti-oncogenes as targets for gene therapy; receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukemias and bone marrow transplantation. The Nato workshop concentrated not only on analysis of cell systems useful for somatic gene therapy, but also on actual themes directly related to correction of human diseases. The latter aspects emphasized themes related to biotechnology, the first part was by nature more general. We also included a few contributions that discussed perspectives for the future of gene therapy and possible relationships to evolution.

Author : Hal E. Broxmeyer
Publisher : American Association of Blood Banks (AABB)
Page : 0 pages
File Size : 47,6 Mb
Release : 2011
Category : Fetal blood
ISBN : 1563953188

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Cord Blood by Hal E. Broxmeyer Pdf

Author : Suzanne Kadereit,Gerald Udolph
Publisher : World Scientific Publishing Company
Page : 372 pages
File Size : 54,8 Mb
Release : 2010-12-23
Category : Science
ISBN : 9789813107311

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Umbilical Cord Blood by Suzanne Kadereit,Gerald Udolph Pdf

Umbilical cord blood, previously discarded, has emerged as a new source of stem cells for hematologic reconstitution, bone marrow failures and other hematologic deficiencies. It has become increasingly clear that umbilical cord tissue contains unique stem cells of great potential for regenerative medicine. Importantly, umbilical cord blood is abundant, can be banked and transported with ease, and thus has an indisputable potential for future regenerative therapies. Driven by a massive interest for regenerative medicine and ethically acceptable stem cell sources, the scientific literature on umbilical cord stem cells has exploded. This book provides a consolidated overview of basic, translational as well as clinical research in academic institutions and industry, on hematopoietic and mesenchymal stem cells contained within umbilical cord tissue, as well as other more recently discovered stem and precursor cells of not yet fully elucidated potential. Although not discussed here, umbilical cord cells have been successfully reprogrammed into pluripotent stem cells (iPS), opening the door for a vast array of applications with this abundant human material likely catapulting cord-derived stem cells to the forefront of cell-based regenerative medicine. Suitable as a primer and reference book for medical fellows and researchers, this book can also be used by students (undergraduate and graduate) as a starting point into the vast literature on stem cells and their potential.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 40,5 Mb
Release : 19??
Category : Electronic
ISBN : 9535128663

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Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine by Anonim Pdf

Author : David A. Steenblock,Anthony G. Payne
Publisher : Basic Health Publications, Inc.
Page : 202 pages
File Size : 40,6 Mb
Release : 2006
Category : Health & Fitness
ISBN : 159120125X

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Umbilical Cord Stem Cell Therapy by David A. Steenblock,Anthony G. Payne Pdf

Examines the potential for stem cells gleaned from umbilical cords to generate a wealth of new therapy and healing medicines for neurological conditions and blood problems.

Author : Anthony Atala
Publisher : Elsevier
Page : 561 pages
File Size : 49,9 Mb
Release : 2012-03-15
Category : Technology & Engineering
ISBN : 9780857096074

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Progenitor and Stem Cell Technologies and Therapies by Anthony Atala Pdf

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Author : Mikkael A. Sekeres
Publisher : MIT Press
Page : 325 pages
File Size : 42,5 Mb
Release : 2021-08-17
Category : Medical
ISBN : 9780262542258

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When Blood Breaks Down by Mikkael A. Sekeres Pdf

A leading cancer specialist tells the powerful stories of 3 adult leukemia patients—shining new light on the hidden history of the disease and the drugs developed to treat it. “A look at leukemia patients’ fear, survival and grace while fighting the disease . . . a quiet chronicle of life with and beyond leukemia, and sometimes life’s end.” —The Washington Post When you are told that you have leukemia, your world stops. Your brain can’t function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together. Sekeres, who writes regularly for the “Well” section of The New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family’s wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimate conversations between Sekeres and his patients, and we watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it—describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia. The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

Author : Nicolaus Kröger,Mohamad Mohty,Carlo Dufour
Publisher : Unknown
Page : 688 pages
File Size : 52,7 Mb
Release : 2020-10-08
Category : Medical
ISBN : 1013273672

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The EBMT Handbook by Nicolaus Kröger,Mohamad Mohty,Carlo Dufour Pdf

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.