Current And Future Immunosuppressive Therapies Following Transplantation

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Current and Future Immunosuppressive Therapies Following Transplantation

Giuseppe Remuzzi
Current and Future Immunosuppressive Therapies Following Transplantation Book PDF

Author : Giuseppe Remuzzi
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 54,9 Mb
Release : 2011-06-28
Category : Medical
ISBN : 9789401010054

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Current and Future Immunosuppressive Therapies Following Transplantation by Giuseppe Remuzzi Pdf

This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. The uniqueness of this book is the inclusion of up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of outstanding investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book is also useful for basic scientists who work in the field of transplantation immunology.

Extending Medicare Coverage for Preventive and Other Services

Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions
Extending Medicare Coverage for Preventive and Other Services Book PDF

Author : Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions
Publisher : National Academies Press
Page : 410 pages
File Size : 55,8 Mb
Release : 2000-05-07
Category : Medical
ISBN : 9780309068895

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Extending Medicare Coverage for Preventive and Other Services by Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions Pdf

This report, which was developed by an expert committee of the Institute of Medicine, reviews the first three services listed above. It is intended to assist policymakers by providing syntheses of the best evidence available about the effectiveness of these services and by estimating the cost to Medicare of covering them. For each service or condition examined, the committee commissioned a review of the scientific literature that was presented and discussed at a public workshop. As requested by Congress, this report includes explicit estimates only of costs to Medicare, not costs to beneficiaries, their families, or others. It also does not include cost-effectiveness analyses. That is, the extent of the benefits relative to the costs to Medicareâ€"or to society generallyâ€"is not evaluated for the services examined. The method for estimating Medicare costs follows the generic estimation practices of the Congressional Budget Office (CBO). The objective was to provide Congress with estimates that were based on familiar procedures and could be compared readily with earlier and later CBO estimates. For each condition or service, the estimates are intended to suggest the order of magnitude of the costs to Medicare of extending coverage, but the estimates could be considerably higher or lower than what Medicare might actually spend were coverage policies changed. The estimates cover the five-year period 2000-2004. In addition to the conclusions about specific coverage issues, the report examines some broader concerns about the processes for making coverage decisions and about the research and organizational infrastructure for these decisions. It also briefly examines the limits of coverage as a means of improving health services and outcomes and the limits of evidence as a means of resolving policy and ethical questions.

Current Issues and Future Direction in Kidney Transplantation

Thomas Rath
Current Issues and Future Direction in Kidney Transplantation Book PDF

Author : Thomas Rath
Publisher : BoD – Books on Demand
Page : 494 pages
File Size : 47,9 Mb
Release : 2013-02-13
Category : Medical
ISBN : 9789535109853

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Current Issues and Future Direction in Kidney Transplantation by Thomas Rath Pdf

The here presented book covers different areas of clinical and scientific interest, reaching from donor evaluation to newest methods in immunological diagnostics. But also aspects of daily care of transplant recipients can be found in the carefully selected chapters. Everything driven by the aim to improve the care for all of our transplanted patients.

Organ Donation and Transplantation

Georgios Tsoulfas
Organ Donation and Transplantation Book PDF

Author : Georgios Tsoulfas
Publisher : BoD – Books on Demand
Page : 454 pages
File Size : 54,7 Mb
Release : 2018-07-25
Category : Medical
ISBN : 9781789233407

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Organ Donation and Transplantation by Georgios Tsoulfas Pdf

One of the most interesting and at the same time most challenging fields of medicine and surgery has been that of organ donation and transplantation. It is a field that has made tremendous strides during the last few decades through the combined input and efforts of scientists from various specialties. What started as a dream of pioneers has become a reality for the thousands of our patients whose lives can now be saved and improved. However, at the same time, the challenges remain significant and so do the expectations. This book will be a collection of chapters describing these same challenges involved including the ethical, legal, and medical issues in organ donation and the technical and immunological problems the experts are facing involved in the care of these patients.The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of organ donation and transplantation.

Uterus Transplantation

Mats Brännström
Uterus Transplantation Book PDF

Author : Mats Brännström
Publisher : Springer Nature
Page : 226 pages
File Size : 41,7 Mb
Release : 2019-11-30
Category : Health & Fitness
ISBN : 9783319941622

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Uterus Transplantation by Mats Brännström Pdf

This book discusses all aspects of the uterus transplantation procedure in women who are childless because of a dysfunctional or missing uterus, from initial pre-operative investigations to follow-up after the uterine graft has been removed. All the international experts who are engaged in clinical activities and/or research in this field have contributed one or more of the book’s chapters. Since the first live birth following uterus transplantation was reported in Sweden in September 2014, the field has been rapidly evolving around the globe: the first cases in USA, Germany, China, Brazil, and Czech Republic were performed in 2016 and several other centres are preparing for clinical trials of uterus transplantation. Uterus transplantation is a subject that attracts the attention of many bioethicists, and like all other major procedures in transplantation surgery and assisted reproduction techniques, it is a complex process that requires a multidisciplinary team if it is to be successful. As such the book is a valuable resource not only for clinicians from many disciplines, but also for nurses, ethicists, psychologists and researchers.

Multiple Primary Malignancies

Andrea Renda
Multiple Primary Malignancies Book PDF

Author : Andrea Renda
Publisher : Springer Science & Business Media
Page : 300 pages
File Size : 41,8 Mb
Release : 2009-02-11
Category : Medical
ISBN : 9788847010956

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Multiple Primary Malignancies by Andrea Renda Pdf

In 2006, when my colleague Andrea Renda proposed multiple primary malignancies (MPM) as the subject of the Biennial Report to the 2008 Congress of the Italian - ciety of Surgery, I, together with the Steering Committee, quickly agreed. Recent progress in our understanding of the etiopathology of these neoplasms has led to - novative and significant progress on the clinical level. Importantly, the incidence of the onset of two or more tumors in the same patient suggests a more than casual - lationship. Furthermore, the occurrence of MPM derives from several different me- anisms—viral, iatrogenic, immunologic, environmental, and hereditary—such that any form of treatment must take into account the etiology of these tumors. After an epidemiological introduction, this monograph analyzes various aspects of multitumoral syndromes based on the experience of the Department of Surgical Sciences, along with that of other clinical departments of the University Federico II of Naples. In the discussion of inherited tumors, reference is made to the series of patients treated at the Department of Surgery at the University of Siena. The many topics that comprise this volume range from carcinogenesis to diagnostic strategies, and from epidemiology to innovations in imaging and endoscopic techniques. Among the clinical aspects, particular emphasis is given to sporadic and hereditary syndromes, as these patients are frequently treated by general surgery departments.

Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

Renato Alberto Sinico,Loïc Guillevin
Anti Neutrophil Cytoplasmic Antibody ANCA Associated Vasculitis Book PDF

Author : Renato Alberto Sinico,Loïc Guillevin
Publisher : Springer Nature
Page : 336 pages
File Size : 44,9 Mb
Release : 2019-09-13
Category : Medical
ISBN : 9783030022396

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Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis by Renato Alberto Sinico,Loïc Guillevin Pdf

This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome). This volume will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these diseases.

Holland-Frei Cancer Medicine

Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Holland Frei Cancer Medicine Book PDF

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 42,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The European Blood and Marrow Transplantation Textbook for Nurses

Michelle Kenyon,Aleksandra Babic
The European Blood and Marrow Transplantation Textbook for Nurses Book PDF

Author : Michelle Kenyon,Aleksandra Babic
Publisher : Springer
Page : 311 pages
File Size : 46,5 Mb
Release : 2018-03-14
Category : Medical
ISBN : 9783319500263

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The European Blood and Marrow Transplantation Textbook for Nurses by Michelle Kenyon,Aleksandra Babic Pdf

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Molecules and Medicine

E. J. Corey,Barbara Czakó,László Kürti
Molecules and Medicine Book PDF

Author : E. J. Corey,Barbara Czakó,László Kürti
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 44,8 Mb
Release : 2012-02-28
Category : Science
ISBN : 9781118361733

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Molecules and Medicine by E. J. Corey,Barbara Czakó,László Kürti Pdf

Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Therapeutic Immunosuppression

A.W. Thomson
Therapeutic Immunosuppression Book PDF

Author : A.W. Thomson
Publisher : Springer Science & Business Media
Page : 516 pages
File Size : 52,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401007658

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Therapeutic Immunosuppression by A.W. Thomson Pdf

Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin disease, and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. In addition, products of the biotechnology industry - monoclonal antibodies, cytokines, cytokine antagonists, and other products of genetic engineering that target key molecular pathways in disease pathogenesis - have either already made, or are on the verge of making an important impact on treatment. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. Gene therapy offers considerable promise for suppressing pathogenic processes in either transplantation or autoimmune disorders. The possibility of combining these important new advances to maximize benefit to the patient, and to minimize possible untoward effects (which are also given extensive coverage in this book), is one of the most exciting challenges of contemporary medicine. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area. Each chapter is contributed by one or more experts in the field. There was a need to bring this information together in a single volume, as much of the key recent developments have been dispersed throughout the biomedical literature, largely in specialized journals. Since, as in the past, important developments in immunosuppressive therapy in one branch of medicine (i.e. transplantation) are likely to benefit another (e.g., dermatology, rheumatology, gastroenterology), cross-disciplinary coverage of the mechanistic basis of the various therapeutic strategies in a single volume is likely to convey the potential of advances in therapy in the most coherent manner possible.

Understanding the Complexities of Kidney Transplantation

Jorge Ortiz,Jason Andre
Understanding the Complexities of Kidney Transplantation Book PDF

Author : Jorge Ortiz,Jason Andre
Publisher : BoD – Books on Demand
Page : 578 pages
File Size : 53,7 Mb
Release : 2011-09-06
Category : Medical
ISBN : 9789533078199

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Understanding the Complexities of Kidney Transplantation by Jorge Ortiz,Jason Andre Pdf

Kidney transplantation is a complex field that incorporates several different specialties to manage the transplant patient. This book was created because of the importance of kidney transplantation. This volume focuses on the complexities of the transplant patient. In particular, there is a focus on the comorbidities and special considerations for a transplant patient and how they affect kidney transplant outcomes. Contributors to this book are from all over the world and are experts in their individual fields. They were all individually approached to add a chapter to this book and with their efforts this book was formed. Understanding the Complexities of Kidney Transplantation gives the reader an excellent foundation to build upon to truly understand kidney transplantation.

Canadian Immunization Guide

Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Canadian Immunization Guide Book PDF

Author : Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publisher : Unknown
Page : 392 pages
File Size : 54,7 Mb
Release : 2006
Category : Immunization
ISBN : 0660193922

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Canadian Immunization Guide by Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization Pdf

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Immunotherapy

Krassimir Metodiev
Immunotherapy Book PDF

Author : Krassimir Metodiev
Publisher : BoD – Books on Demand
Page : 416 pages
File Size : 51,7 Mb
Release : 2017-04-26
Category : Medical
ISBN : 9789535131052

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Immunotherapy by Krassimir Metodiev Pdf

This is another attempt of InTechOpen to continue the dissemination of international knowledge and experience in the field of immunology. The present book includes a number of modern concepts of specialists and experts in the field of immunotherapy, covering the major topics and analyzing the history, current stage, and future ideas of application of modern immunomodulation. It is always a benefit, but also a compliment, to gather a team of internationally distinguished authors and to motivate them to reveal their expertise for the benefit of medical science and health practice. On behalf of all readers, immunologists, immunogeneticists, biologists, oncologists, microbiologists, virologists, hematologists, chemotherapists, health-care experts, as well as students and medical specialists, also on my personal behalf, I would like to extend my gratitude and highest appreciation to InTechOpen for giving me the unique chance to be the editor of this exclusive book.

Clinical Guide to Heart Transplantation

Jon Kobashigawa
Clinical Guide to Heart Transplantation Book PDF

Author : Jon Kobashigawa
Publisher : Springer
Page : 258 pages
File Size : 45,5 Mb
Release : 2017-03-29
Category : Medical
ISBN : 9783319437736

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Clinical Guide to Heart Transplantation by Jon Kobashigawa Pdf

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​