Current Technologies To Increase The Transdermal Delivery Of Drugs

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Current Technologies To Increase The Transdermal Delivery Of Drugs

José Juan Escobar-Chávez
Current Technologies To Increase The Transdermal Delivery Of Drugs Book PDF

Author : José Juan Escobar-Chávez
Publisher : Bentham Science Publishers
Page : 155 pages
File Size : 40,9 Mb
Release : 2010
Category : Medical
ISBN : 9781608051915

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Current Technologies To Increase The Transdermal Delivery Of Drugs by José Juan Escobar-Chávez Pdf

This e-book provides an overview of current technologies used to increase the topical/transdermal delivery of drugs, its protocols, advantages and limitations. It includes exclusive chapters on chemical enhancers, Iontophoresis, Sonophoresis, Electroporation, Microneedles and the more recent use of micro/nanoparticles to deliver drugs throughout the skin. The e-book's generalized approach on the topic is aimed to be helpful in drug discovery, drug delivery and toxicological research and to provide a broader perspective on the topic to readers with respect to current literature available on the.

Physical Penetration Enhancers: Therapeutic Applications and Devices

José Juan Escobar-Chávez
Physical Penetration Enhancers Therapeutic Applications and Devices Book PDF

Author : José Juan Escobar-Chávez
Publisher : Bentham Science Publishers
Page : 342 pages
File Size : 49,7 Mb
Release : 2016-11-24
Category : Medical
ISBN : 9781681083636

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Physical Penetration Enhancers: Therapeutic Applications and Devices by José Juan Escobar-Chávez Pdf

This volume covers the methods of using skin penetrating agents, the therapeutic applications of physical penetration enhancers and devices in the market. Chapters cover topics such as transdermal drug delivery through iontophoresis, gene therapy, physiotherapy, skin disorders, vaccination, and pharmacology. Devices covered in this volume include micro needles, nano-carrier and gene delivery systems. This volume is a handy resource for professionals in medicine (dermatologists), biopharmacy, pharmaceutical technology, drug design and development (scientists and pharmaceutical R&D executives).

Imaging Technologies and Transdermal Delivery in Skin Disorders

Chenjie Xu,Xiaomeng Wang,Manojit Pramanik
Imaging Technologies and Transdermal Delivery in Skin Disorders Book PDF

Author : Chenjie Xu,Xiaomeng Wang,Manojit Pramanik
Publisher : John Wiley & Sons
Page : 498 pages
File Size : 43,9 Mb
Release : 2020-03-09
Category : Science
ISBN : 9783527344604

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Imaging Technologies and Transdermal Delivery in Skin Disorders by Chenjie Xu,Xiaomeng Wang,Manojit Pramanik Pdf

Provides the latest information on imaging technologies and transdermal delivery in skin disorders This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work. Imaging Technologies and Transdermal Delivery in Skin Disorders starts by outlining the structural characteristics of skin and skin appendages. It then discusses the key pathways involved in skin growth and development. Clinical presentations, pathophysiological mechanisms, and current clinical practices used to treat diseases affecting the skin are then introduced. Common preclinical models used for studying the mechanisms of diverse skin diseases, validation of novel therapeutic targets, and screening of new drugs to treat these diseases are also covered. The book examines the latest imaging technologies for understanding in vivo skin changes, as well as technologies such as high-resolution ultrasound imaging, quantitative Magnetic Resonance Imaging, high-resolution Optical Coherence Tomography, and emerging hybrid-imaging modalities. It concludes with chapters introducing emerging drug delivery technologies and potential future innovative developments. * Presents up-to-date knowledge of the skin biology and pathologies * Introduces advancements in the topic of imaging technology for tracing the drug delivery process, which is rarely systematically reported by other counterparts * Covers the latest development in three inter-related directions of drug delivery, imaging, and skin disease intersect for skin research * Provides an overview of the latest development of diagnostic and therapeutic technologies for skin diseases Imaging Technologies and Transdermal Delivery in Skin Disorders will be of great interest to analytical chemists, materials scientists, pharmaceutical chemists, clinical chemists, biotechnologists, bioengineers, cosmetics industry, and dermatologists.

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Ryan F. Donnelly,Thakur Raghu Raj Singh
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery Book PDF

Author : Ryan F. Donnelly,Thakur Raghu Raj Singh
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 42,7 Mb
Release : 2015-08-07
Category : Science
ISBN : 9781118734483

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Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by Ryan F. Donnelly,Thakur Raghu Raj Singh Pdf

This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Transdermal Drug Delivery

Kevin Ita
Transdermal Drug Delivery Book PDF

Author : Kevin Ita
Publisher : Academic Press
Page : 324 pages
File Size : 43,7 Mb
Release : 2020-06-12
Category : Business & Economics
ISBN : 9780128225516

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Transdermal Drug Delivery by Kevin Ita Pdf

Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful. Captures the most recent advancements and challenges in the field of transdermal drug delivery Covers both passive and active transdermal drug delivery strategies Explores a selection of state-of-the-art transdermal drug delivery systems

Topical and Transdermal Drug Delivery

Heather A. E. Benson,Adam C. Watkinson
Topical and Transdermal Drug Delivery Book PDF

Author : Heather A. E. Benson,Adam C. Watkinson
Publisher : John Wiley & Sons
Page : 393 pages
File Size : 52,8 Mb
Release : 2012-02-03
Category : Medical
ISBN : 9781118140499

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Topical and Transdermal Drug Delivery by Heather A. E. Benson,Adam C. Watkinson Pdf

Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.

Advanced Technology for Delivering Therapeutics

Sabyasachi Maiti,Kalyan Kumar Sen
Advanced Technology for Delivering Therapeutics Book PDF

Author : Sabyasachi Maiti,Kalyan Kumar Sen
Publisher : BoD – Books on Demand
Page : 186 pages
File Size : 47,9 Mb
Release : 2017-05-11
Category : Medical
ISBN : 9789535131212

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Advanced Technology for Delivering Therapeutics by Sabyasachi Maiti,Kalyan Kumar Sen Pdf

The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology currently being investigated for drug delivery applications. This book is a useful source of information for graduate and post-graduate students of pharmacy and biomedical science; pharmaceutical

Recent Advances in Novel Drug Carrier Systems

Ali Demir Sezer
Recent Advances in Novel Drug Carrier Systems Book PDF

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Page : 516 pages
File Size : 46,6 Mb
Release : 2012-10-31
Category : Medical
ISBN : 9789535108108

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Recent Advances in Novel Drug Carrier Systems by Ali Demir Sezer Pdf

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Drug Delivery Systems

Kewal K. Jain
Drug Delivery Systems Book PDF

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 54,7 Mb
Release : 2008-03-07
Category : Science
ISBN : 9781588298911

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Drug Delivery Systems by Kewal K. Jain Pdf

In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.

Novel Drug Delivery Technologies

Ambikanandan Misra,Aliasgar Shahiwala
Novel Drug Delivery Technologies Book PDF

Author : Ambikanandan Misra,Aliasgar Shahiwala
Publisher : Springer Nature
Page : 448 pages
File Size : 47,7 Mb
Release : 2020-02-12
Category : Medical
ISBN : 9789811336423

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Novel Drug Delivery Technologies by Ambikanandan Misra,Aliasgar Shahiwala Pdf

The application of drug delivery is a valuable, cost-effective lifecycle management resource. By endowing drugs with new and innovative therapeutic benefits, drug delivery systems extend products’ profitable lifecycle, giving pharmaceutical companies competitive and financial advantages, and providing patients with improved medications. Formulation development is now being used to create new dosage forms for existing products, which not only reduces the time and expense involved in new drug development, but also helps with regard to patent protection and bypassing existing patents. Today’s culture demands convenience, a major factor determining adherence to drug therapy. Over the past few years, patient convenience-oriented research in the field of drug delivery has yielded a range of innovative drug-delivery options. As a result, various drug-delivery systems, including medicated chewing gums, oral dispersible tablets, medicated lozenges and lollipops, have now hit the market and are very popular. These dosage forms offer a highly convenient way to dose medications, not only for special population groups with swallowing difficulties, such as children and the elderly, but for the general populace as well. This book provides valuable insights into a number of formulation design approaches that are currently being used, or could be used, to provide new benefits from existing drug molecules.

Skin Delivery Systems

John J. Wille
Skin Delivery Systems Book PDF

Author : John J. Wille
Publisher : Wiley-Blackwell
Page : 404 pages
File Size : 53,5 Mb
Release : 2006-06-26
Category : Science
ISBN : 0813808480

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Skin Delivery Systems by John J. Wille Pdf

Current interest in drug delivery technologies is exceedingly high. Similarly, a recent upsurge in consumer awareness of the potential antiaging and antiwrinkling benefits of natural products and botanicals has spurred a revolution in the cosmetic industry for better skin care delivery technologies, both to preserve inherent activity as well as to enhance their benefits through novel formulation and delivery methods. With these considerations in mind, Skin Delivery Systems: Transdermals, Dermatologicals and Cosmetic Actives brings together the emerging fields of cosmetic actives with new advances in skin delivery technologies and provides a methodical and systematic explanation of technologies used to transport pharmaceuticals and cosmetic actives through the skin's barriers. After reviewing the basic principles of dermatology and skin penetration, the reference describes and explains the most current methods of transdermal transport. Coverage includes new materials, such as amphiphilic polymers; new formulation methods, such as miniemulsions; and variations on technologies such as sonophoresis and iontophoresis. The authors also show the connections between skin penetration and a variety of active substances, including specialized pharmaceuticals and natural and botanical ingredients used in cosmetics. The book presents critical empirical data and design information intended to assist researchers, product developers, and testers in the pharmaceutical and cosmetics industries.

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Jorge Coelho
Drug Delivery Systems Advanced Technologies Potentially Applicable in Personalised Treatment Book PDF

Author : Jorge Coelho
Publisher : Springer Science & Business Media
Page : 433 pages
File Size : 40,7 Mb
Release : 2013-03-15
Category : Medical
ISBN : 9789400760103

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Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by Jorge Coelho Pdf

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Handbook of Non-Invasive Drug Delivery Systems

Vitthal S. Kulkarni
Handbook of Non Invasive Drug Delivery Systems Book PDF

Author : Vitthal S. Kulkarni
Publisher : Elsevier
Page : 328 pages
File Size : 49,8 Mb
Release : 2009-12-31
Category : Medical
ISBN : 0815520263

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Handbook of Non-Invasive Drug Delivery Systems by Vitthal S. Kulkarni Pdf

With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery. The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.

Focal Controlled Drug Delivery

Abraham J. Domb,Wahid Khan
Focal Controlled Drug Delivery Book PDF

Author : Abraham J. Domb,Wahid Khan
Publisher : Springer Science & Business Media
Page : 700 pages
File Size : 49,6 Mb
Release : 2014-02-17
Category : Medical
ISBN : 9781461494348

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Focal Controlled Drug Delivery by Abraham J. Domb,Wahid Khan Pdf

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

Introduction to Basics of Pharmacology and Toxicology

Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj
Introduction to Basics of Pharmacology and Toxicology Book PDF

Author : Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj
Publisher : Springer Nature
Page : 1156 pages
File Size : 45,8 Mb
Release : 2021-03-13
Category : Medical
ISBN : 9789813360099

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Introduction to Basics of Pharmacology and Toxicology by Abialbon Paul,Nishanthi Anandabaskar,Jayanthi Mathaiyan,Gerard Marshall Raj Pdf

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.