Current Trends In The Diagnosis And Management Of Metabolic Disorders

Author : Seth Kwabena Amponsah,Emmanuel Kwaku Ofori,Yashwant V. Pathak
Publisher : CRC Press
Page : 375 pages
File Size : 54,7 Mb
Release : 2023-12-14
Category : Medical
ISBN : 9781003817345

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Current Trends in the Diagnosis and Management of Metabolic Disorders by Seth Kwabena Amponsah,Emmanuel Kwaku Ofori,Yashwant V. Pathak Pdf

This volume provides an overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies. Metabolic disorders occur when metabolic processes in the body are disrupted. They contribute a significant burden to human health globally. They can be congenital or acquired, for example, diabetes mellitus, obesity, metabolic syndrome, osteoporosis, osteopenia, mild-moderate hypovitaminosis D, erectile dysfunction, dyslipidemia, and thyroiditis. Metabolic disorders have gained significant importance due to the exponential increase in obesity worldwide. Early diagnosis of metabolic disorders is important in order to employ lifestyle and risk factor modification. Features: An overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies Describes recent trends in diagnosis of metabolic disorders Discusses management and treatment of metabolic diseases Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds Suitable globally for graduate and postgraduate students studying metabolic diseases

Author : Juliet E. Compston,Jane B. Lian
Publisher : John Wiley & Sons
Page : 559 pages
File Size : 49,8 Mb
Release : 2009-12-22
Category : Science
ISBN : 9780470623985

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Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism by Juliet E. Compston,Jane B. Lian Pdf

EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.

Author : Gerald S. Berenson
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 46,9 Mb
Release : 2011-07-09
Category : Medical
ISBN : 9789400714519

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Evolution of Cardio-Metabolic Risk from Birth to Middle Age by Gerald S. Berenson Pdf

That precursors of adult coronary artery disease, hypertension, and type II diabetes begin in childhood have been clearly established by the Bogalusa Heart Study. This unique research program has been able to follow a biracial (black/white) population over 35 years from childhood through mid-adulthood to provide perspectives on the natural history of adult heart diseases. Not only do these observations describe trajectories of cardio-metabolic risk variables leading to these diseases but provide a rationale for the need to begin prevention beginning in childhood. The trajectories of the burden of cardio-metabolic risk variables in the context of their fetal origin and chromosome telomere dynamics provide some insight into the metabolic imprinting in utero and aging process. The observed racial contrasts on cardio-metabolic risk variables implicate various biologic pathways interacting with environment contributing to the high morbidity and mortality from related diseases in our population. To address the seriousness of the onset of cardiovascular disease in youth, approaches to primordial prevention are described focussing on childhood health education as an important aspect of Preventive Cardiology.

Author : A Parthasarathy,Alok Gupta
Publisher : Jaypee Brothers Medical Publishers
Page : 527 pages
File Size : 55,9 Mb
Release : 2021-03-10
Category : Medical
ISBN : 9789390595150

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Partha's Current Trends in Diagnosis & Management for Pediatric & Adolescent Practitioners by A Parthasarathy,Alok Gupta Pdf

Author : Thomas Seyfried
Publisher : John Wiley & Sons
Page : 482 pages
File Size : 54,9 Mb
Release : 2012-05-18
Category : Science
ISBN : 9781118310304

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Cancer as a Metabolic Disease by Thomas Seyfried Pdf

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Author : Laurie E. Bernstein,Fran Rohr,Sandy van Calcar
Publisher : Springer Nature
Page : 415 pages
File Size : 52,5 Mb
Release : 2022-06-14
Category : Medical
ISBN : 9783030945107

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Nutrition Management of Inherited Metabolic Diseases by Laurie E. Bernstein,Fran Rohr,Sandy van Calcar Pdf

This text presents a compilation of topics that have been taught at Metabolic University (MU), an interactive, didactic educational program that has trained over 600 metabolic dietitians/nutritionists, physicians, nurses and genetic counselors. This book was created in 2014 for the metabolic community. The 1st edition contains only subject matter covered at Metabolic University; therefore, it is not a comprehensive treatise on Inherited Metabolic Disorders (IMD) but rather a text on the most frequently encountered challenges in IMD nutrition. Each chapter in the book highlights principles of nutrition management, how to initiate a diet, and biomarkers to monitor the diet. Recognizing that there are variations in practice, this book addresses that the key to management lies in the understanding how the inactivity of an enzyme in a metabolic pathway determines which components of the diet must be restricted and which must be supplemented as well as the monitoring of appropriate biomarkers to make diet adjustments and ensure the goals of therapy are met The 2nd edition is an updated and more extensive version covering the nutrition management of IMD, and covers a wide range of these disorders, including phenylketonuria and other aminoacidopathies, organic acidemias, urea cycle disorders, fatty acid oxidation disorders, galactosemia and glycogen storage diseases. Guidance is also provided on laboratory evaluations and biochemical testing and monitoring. Topics such as newborn screening for IMD, as well as nutrition management during pregnancy and transplantation, are also addressed. In addition, current medical management therapies is included.

Author : Kim A. Sprayberry,N. Edward Robinson
Publisher : Elsevier Health Sciences
Page : 1024 pages
File Size : 54,8 Mb
Release : 2014-08-19
Category : Medical
ISBN : 9780323242165

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Robinson's Current Therapy in Equine Medicine - E-Book by Kim A. Sprayberry,N. Edward Robinson Pdf

With coverage of current issues and the latest therapeutic advances, Robinson’s Current Therapy in Equine Medicine, Volume 7 provides a concise, all-new reference for the management of equine disorders and conditions. Chapters emphasize the practical aspects of diagnosis and treatment and provide details for therapeutic regimens. This new volume brings you thorough coverage and authoritative advice on selected topics in areas that have seen significant advances in the last five years. Cutting-edge topics include emerging and exotic infectious diseases that may endanger horses in North America; biosecurity strategies; imaging updates; medical genetics; multimodal pain management; and regenerative, geriatric, and oncologic medicine. A logical body-system organization will save you time in finding the information you need. From well-known editors Kim Sprayberry and N. Edward Robinson, with chapters written by nearly 200 equine experts, this invaluable reference provides unparalleled guidance on the latest issues in equine medicine. Key topics include all-new coverage of the latest developments in imaging, biosecurity strategies for individual horse owners and owners of commercial farms and stables, diseases affecting horses at various ages, and a review of colic and other GI tract conditions. A recognized panel of nearly 200 expert contributors represents thriving private equine practices, referral hospitals, and academia, and provides insight on challenges, developments, and differing perspectives from around the world. A succinct approach is used to discuss pathophysiology and diagnosis, but therapeutics are covered in detail. The Current Therapy format focuses on emerging trends, treatment protocols, and diagnostic updates new to the field, providing timely information on the latest advances in equine medicine. A body systems organization makes it easy to find solutions for specific disorders. Suggested readings at the end of each chapter cite peer-reviewed articles and other sources for further research and study. ALL-NEW topics provide updates on infectious diseases, including herpesvirus, equine granulocytic anaplasmosis, and lawsonia infection and proliferative enteropathy; pain diagnosis and multimodal management; management of thoracic and airway trauma, imaging, endoscopy, and other diagnostic procedures for the acute abdomen; and neurologic injury. 212 concise, NEW chapters include both a succinct guide to diagnosis of disorders and a detailed discussion of therapy. NEW images demonstrate advances in various imaging techniques. Thoroughly updated drug appendices, including all-new coverage of drug dosages for donkeys and mules, provide a handy, quick reference for the clinical setting.

Author : Nenad Blau,Marinus Duran,K Michael Gibson,Carlo Dionisi Vici
Publisher : Springer
Page : 867 pages
File Size : 53,7 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9783642403378

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Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases by Nenad Blau,Marinus Duran,K Michael Gibson,Carlo Dionisi Vici Pdf

This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.

Author : Hussain, Arif,Behl, Shalini
Publisher : IGI Global
Page : 489 pages
File Size : 50,9 Mb
Release : 2020-12-11
Category : Medical
ISBN : 9781799848097

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Treating Endocrine and Metabolic Disorders With Herbal Medicines by Hussain, Arif,Behl, Shalini Pdf

The utilization of herbal medicine to treat endocrine and metabolic disorders has garnered much attention within the past few decades. Specifically, the popularity of using dietary supplements for the management of chronic disorders has drastically increased, with a wide variety of these products available over the counter. They represent an attractive adjuvant to traditional therapy for their lower toxicity and their easy accessibility. The identification of such dietary compounds has prompted researchers to explore the vast array of their beneficial effects. However, despite their widespread use, there is still limited data on the safety and efficacy of the products currently on the market. Current research on the side effects and safe usage of herbal medicines is necessary for providing optimal care and counseling for patients. Treating Endocrine and Metabolic Disorders With Herbal Medicines is a comprehensive reference book focused on spreading awareness on the safety, potential harmful effects, and rational use of herbal medicines. The chapters within explore and provide insight on the effectiveness, versatility, and side effects of various herbal medicines across a range of different diseases and conditions. While highlighting herbal medicine in areas such as diabetes, cancer, infertility, and endocrine disorders, this publication is ideally intended for clinical practitioners, pharmaceutical scientists, doctors, practitioners, stakeholders, researchers, academicians, and students interested in enhancing their knowledge and awareness in the field of complementary medicine.

Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care
Publisher : National Academies Press
Page : 473 pages
File Size : 44,8 Mb
Release : 2015-12-29
Category : Medical
ISBN : 9780309377720

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Improving Diagnosis in Health Care by National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care Pdf

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Author : Merlin Butler,Phillip D.K. Lee,Barbara Y. Whitman
Publisher : Springer Science & Business Media
Page : 569 pages
File Size : 42,9 Mb
Release : 2006-10-11
Category : Medical
ISBN : 9780387335360

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Management of Prader-Willi Syndrome by Merlin Butler,Phillip D.K. Lee,Barbara Y. Whitman Pdf

Management of Prader-Willi Syndrome brings together the contributions of professionals with considerable expertise in diagnosis and management of PWS. Clinical, social, family, and community issues are explored and management strategies identified. The text presents historical, medical, and genetic information to orient the reader. The major portion deals with pragmatic guidelines, rather than research and diagnosis, and is directed to health and educational specialists in academic, clinical, and community settings. This manual is endorsed by The Prader-Willi Syndrome Association, which is recognized world-wide.

Author : Gojka Roglic
Publisher : Unknown
Page : 0 pages
File Size : 43,8 Mb
Release : 2016
Category : Medical
ISBN : 924156525X

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Global Report on Diabetes by Gojka Roglic Pdf

"On the occasion of World Health Day 2016, WHO issues a call for action on diabetes, drawing attention to the need to step up prevention and treatment of the disease. The first WHO Global report on diabetes demonstrates that the number of adults living with diabetes has almost quadrupled since 1980 to 422 million adults. This dramatic rise is largely due to the rise in type 2 diabetes and factors driving it include overweight and obesity. In 2012 alone diabetes caused 1.5 million deaths. Its complications can lead to heart attack, stroke, blindness, kidney failure and lower limb amputation. The new report calls upon governments to ensure that people are able to make healthy choices and that health systems are able to diagnose, treat and care for people with diabetes. It encourages us all as individuals to eat healthily, be physically active, and avoid excessive weight gain."--Publisher's description.

Author : Harish Dureja,Narasimha Murthy,Peter Wich,Kamal Dua
Publisher : Academic Press
Page : 527 pages
File Size : 43,7 Mb
Release : 2022-08-26
Category : Business & Economics
ISBN : 9780323996334

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Drug Delivery Systems for Metabolic Disorders by Harish Dureja,Narasimha Murthy,Peter Wich,Kamal Dua Pdf

Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics. Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases. Offers comprehensive coverage of drug delivery to treat metabolic diseases Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of metabolic disorders Includes the most recent research on diagnostic methods and treatment strategies using controlled drug delivery systems

Author : Viswanathan Mohan,MA Shekar,Gundu HR Rao
Publisher : Jaypee Brothers Medical Publishers
Page : 417 pages
File Size : 45,9 Mb
Release : 2020-11-30
Category : Medical
ISBN : 9789390020171

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Current Trends in Diabetes by Viswanathan Mohan,MA Shekar,Gundu HR Rao Pdf

Diabetes is a disease that occurs when the pancreas does not produce enough insulin to control the amount of glucose in the blood. This book is a comprehensive guide to the latest advances in the diagnosis and treatment of diabetes. Divided into six sections, the manual begins with an overview of diagnosis and classification, followed by discussion on epidemiology and aetiopathogenesis. Section four covers comorbidities and complications of diabetes including hyper- and hypoglycaemia, heart failure, foot ulcers, and diabetic retinopathy. The final sections examine recent advances and technologies. The detailed text is further enhanced by clinical photographs, diagrams and tables to assist learning. Key points Comprehensive guide to latest advances in diagnosis and management of diabetes Discusses diagnosis and classification, epidemiology and aetiopathogenesis Covers many different comorbidities and complications Highly illustrated with clinical photographs, diagrams and tables

Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 528 pages
File Size : 50,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618

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Mitochondrial Dysfunction by Lawrence H. Lash,Dean P. Jones Pdf

Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.