Cytokine Gene Polymorphisms In Multifactorial Conditions

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Cytokine Gene Polymorphisms in Multifactorial Conditions

Koen Vandenbroeck
Cytokine Gene Polymorphisms in Multifactorial Conditions Book PDF

Author : Koen Vandenbroeck
Publisher : CRC Press
Page : 488 pages
File Size : 49,9 Mb
Release : 2006-06-21
Category : Medical
ISBN : 0849336198

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Cytokine Gene Polymorphisms in Multifactorial Conditions by Koen Vandenbroeck Pdf

The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. It discusses haplotype structures and linkage disequilibrium patterns in cytokine gene loci; functional biological effects of polymorphisms; and genetic associations with disease. The book documents polymorphisms in the most important cytokine genes, or gene clusters, and their biological and genetic effects in a multitude of distinct multifactorial conditions. Unique to this book are the "disease-centered" chapters examining the role of cytokine gene polymorphisms in a multitude of multifactorial conditions. The conditions include autoimmune or chronic inflammatory diseases, cardiovascular disease, infectious diseases, and longevity. "This section is a real tour de force" (Grant Gallagher and Michael F. Seldin, March 2006). Broadening the understanding of the effect of genetic variations on human immune responses, the organization, scope, and content of this book make it a valuable and easily accessible resource. The book integrates genetic, immunological, and clinical information and will serve as a reference for novice and expert geneticists, immunologists, cell biologists and clinicians. It is a must for everyone involved in, or planning, cytokine genetics or immunogenetics studies.

Cytokine Gene Polymorphisms in Multifactorial Conditions

Koen Vandenbroeck
Cytokine Gene Polymorphisms in Multifactorial Conditions Book PDF

Author : Koen Vandenbroeck
Publisher : CRC Press
Page : 488 pages
File Size : 42,8 Mb
Release : 2006-06-21
Category : Medical
ISBN : 9781420005325

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Cytokine Gene Polymorphisms in Multifactorial Conditions by Koen Vandenbroeck Pdf

The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. It discusses haplotype structures and linkage disequilibrium patterns in cytokine gene loci; functional biological effects of polymorphisms; and genetic associations with disease. The book documents polymorphisms in the most important cytokine genes, or gene clusters, and their biological and genetic effects in a multitude of distinct multifactorial conditions. Unique to this book are the "disease-centered" chapters examining the role of cytokine gene polymorphisms in a multitude of multifactorial conditions. The conditions include autoimmune or chronic inflammatory diseases, cardiovascular disease, infectious diseases, and longevity. "This section is a real tour de force" (Grant Gallagher and Michael F. Seldin, March 2006). Broadening the understanding of the effect of genetic variations on human immune responses, the organization, scope, and content of this book make it a valuable and easily accessible resource. The book integrates genetic, immunological, and clinical information and will serve as a reference for novice and expert geneticists, immunologists, cell biologists and clinicians. It is a must for everyone involved in, or planning, cytokine genetics or immunogenetics studies.

Infectious Process and Sepsis

Vincenzo Neri
Infectious Process and Sepsis Book PDF

Author : Vincenzo Neri
Publisher : Unknown
Page : 102 pages
File Size : 43,9 Mb
Release : 2020
Category : Electronic
ISBN : 1839629835

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Infectious Process and Sepsis by Vincenzo Neri Pdf

Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis.

Cytokines

Victor R. Preedy,Ross Hunter
Cytokines Book PDF

Author : Victor R. Preedy,Ross Hunter
Publisher : CRC Press
Page : 450 pages
File Size : 43,8 Mb
Release : 2011-06-24
Category : Medical
ISBN : 9781439876206

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Cytokines by Victor R. Preedy,Ross Hunter Pdf

Cytokines are a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes, and T cells. They can be divided into functional families and have-wide ranging impacts that affect cells and molecular pathways to the whole individual. Written by distinguished scholars and experts, this book is a holistic reference to enable scientists and doctors to understand cytokines in specific or broad detail. The book is divided into sections that cover general and cellular aspects, lifestyle factors, immunology and infections, cancer, cardiovascular and metabolic disease, and organs and tissue systems.

Handbook on Immunosenescence

Tamas Fulop,Claudio Franceschi,Katsuiki Hirokawa,Graham Pawelec
Handbook on Immunosenescence Book PDF

Author : Tamas Fulop,Claudio Franceschi,Katsuiki Hirokawa,Graham Pawelec
Publisher : Springer Science & Business Media
Page : 1693 pages
File Size : 44,7 Mb
Release : 2009-02-27
Category : Medical
ISBN : 9781402090639

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Handbook on Immunosenescence by Tamas Fulop,Claudio Franceschi,Katsuiki Hirokawa,Graham Pawelec Pdf

This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Translational Research in Traumatic Brain Injury

Daniel Laskowitz,Gerald Grant
Translational Research in Traumatic Brain Injury Book PDF

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 53,9 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Immunosenescence

Graham Pawelec
Immunosenescence Book PDF

Author : Graham Pawelec
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 54,8 Mb
Release : 2008-12-18
Category : Medical
ISBN : 9780387768427

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Immunosenescence by Graham Pawelec Pdf

Human immunosenescence contributes to morbidity and mortality in later life. Understanding the reasons for age-associated alterations to protective immunity in the elderly would ultimately improve and extend healthspan. The majority of the papers collected in this remarkable and timely volume address the mechanisms responsible for immune ageing in humans. They also consider what might be accomplished to redress the erosion of immune competence with age.

Immunoepidemiology

Peter J. Krause,Paula B. Kavathas,Nancy H. Ruddle
Immunoepidemiology Book PDF

Author : Peter J. Krause,Paula B. Kavathas,Nancy H. Ruddle
Publisher : Springer Nature
Page : 297 pages
File Size : 44,7 Mb
Release : 2019-10-24
Category : Medical
ISBN : 9783030255534

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Immunoepidemiology by Peter J. Krause,Paula B. Kavathas,Nancy H. Ruddle Pdf

This textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.

Biogerontology

Suresh I. S. Rattan,Serif Akman
Biogerontology Book PDF

Author : Suresh I. S. Rattan,Serif Akman
Publisher : Wiley-Blackwell
Page : 592 pages
File Size : 43,6 Mb
Release : 2007-05-07
Category : Family & Relationships
ISBN : STANFORD:36105123513181

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Biogerontology by Suresh I. S. Rattan,Serif Akman Pdf

Biological aging and interventionary strategies are investigated with the eventual goal of extending healthy human lifespan and minimizing the incidence of diseases associated with aging. Biogerontologists, evolutionary biologists, biodemographers, scientists in related basic research, clinicians, and dieticians came together in Istanbul, Turkey, to share their research and discuss the latest developments in this rapidly advancing field. This volume presents chapters representative of the highlights of the meeting, including contributions in the following areas: (1) biological and nonbiological factors affecting lifespan and the quality of life; (2) ethical and social issues related to lifespan and health-span extension; (3) novel areas of understanding aging -- physiological, cellular, and molecular aspects; (4) new technologies to understand and modulate aging; (5) the latest successful approaches in the prevention and treatment of age-related diseases; and (6) aging intervention, prevention, and modulation by genes, natural and synthetic molecules, and lifestyle modifications. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

Oxygen/Nitrogen Radicals: Cell Injury and Disease

Val Vallyathan,Vince Castranova,Xianglin Shi
Oxygen Nitrogen Radicals Cell Injury and Disease Book PDF

Author : Val Vallyathan,Vince Castranova,Xianglin Shi
Publisher : Springer Science & Business Media
Page : 393 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461510871

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Oxygen/Nitrogen Radicals: Cell Injury and Disease by Val Vallyathan,Vince Castranova,Xianglin Shi Pdf

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Genetics and Public Health in the 21st Century

Muin J. Khoury,Wylie Burke,Elizabeth Jean Thomson
Genetics and Public Health in the 21st Century Book PDF

Author : Muin J. Khoury,Wylie Burke,Elizabeth Jean Thomson
Publisher : Oxford University Press, USA
Page : 661 pages
File Size : 49,7 Mb
Release : 2000
Category : Language Arts & Disciplines
ISBN : 9780195128307

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Genetics and Public Health in the 21st Century by Muin J. Khoury,Wylie Burke,Elizabeth Jean Thomson Pdf

The first broad survey of these two fields, this book deleniates a framework for integrating advances in human genetics into public health practice.

Progress in Immunology Research

Barbara A. Veskler
Progress in Immunology Research Book PDF

Author : Barbara A. Veskler
Publisher : Nova Publishers
Page : 274 pages
File Size : 42,5 Mb
Release : 2005
Category : Cellular immunity
ISBN : 1594543801

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Progress in Immunology Research by Barbara A. Veskler Pdf

Immunology is the study of the body's protection from foreign macromolecules or invading organisms and the responses to them. These invaders include viruses, bacteria, protozoa or even larger parasites. In addition, immune responses are developed against our own proteins (and other molecules) in autoimmunity and against our own aberrant cells in tumour immunity. The first line of defence against foreign organisms are barrier tissues such as the skin that stop the entry of organism into our bodies. A second line of defence is the specific or adaptive immune system which may take days to respond to a primary invasion (that is infection by an organism that has not hitherto been seen). This new book brings together new research from around the globe dealing with this extremely important subject.

SIDS Sudden Infant and Early Childhood Death

Roger W. Byard,Jhodie R Duncan
SIDS Sudden Infant and Early Childhood Death Book PDF

Author : Roger W. Byard,Jhodie R Duncan
Publisher : Unknown
Page : 844 pages
File Size : 44,5 Mb
Release : 2018-04
Category : Medical
ISBN : 1925261670

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SIDS Sudden Infant and Early Childhood Death by Roger W. Byard,Jhodie R Duncan Pdf

This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.

Asthma in the Workplace

David I. Bernstein,Jean-Luc Malo
Asthma in the Workplace Book PDF

Author : David I. Bernstein,Jean-Luc Malo
Publisher : CRC Press
Page : 450 pages
File Size : 55,9 Mb
Release : 2013-05-10
Category : Medical
ISBN : 9781841849256

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Asthma in the Workplace by David I. Bernstein,Jean-Luc Malo Pdf

Occupational factors are responsible for a large percentage of cases of asthma in adults of working age. Any irritant generated at high concentrations can cause occupational asthma, and early diagnosis is critical because cure is still possible at this stage. This latest edition of Asthma in the Workplace reflects the rapid pace of discovery and research in workplace asthma that has taken place in recent years. This Fourth Edition retains the international flavor of prior editions, with contributions from editors and contributors from around the world. Several chapters commence with clinical histories and workplace scenarios relevant to the focus of the chapter, making it particularly germane for primary care providers to develop skills in early recognition of the disease. Topics discussed include: Definitions, historical background, epidemiology, genetics, pathophysiology, and animal models Guidelines for assessing the worker and the workplace, and proposed guidelines for management, including compensation aspects Medicolegal aspects, prevention, and surveillance Detailed information about specific agents, including a variety of high- and low-molecular weight agents Other types of work-related asthma conditions, such as irritant-induced asthma, eosinophilic bronchitis, and occupational rhinitis This new edition has been significantly restructured and places a greater emphasis on the clinical aspects of management and treatment. This heightened focus on practical considerations makes it a truly comprehensive, hands-on resource for practitioners and researchers in this fast-moving field.

Genetic Susceptibility to Infectious Diseases

Richard A. Kaslow,Janet McNicholl,Adrian V. S. Hill
Genetic Susceptibility to Infectious Diseases Book PDF

Author : Richard A. Kaslow,Janet McNicholl,Adrian V. S. Hill
Publisher : Oxford University Press
Page : 464 pages
File Size : 51,5 Mb
Release : 2008
Category : Language Arts & Disciplines
ISBN : 9780195174908

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Genetic Susceptibility to Infectious Diseases by Richard A. Kaslow,Janet McNicholl,Adrian V. S. Hill Pdf

Infectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. This text uniquely focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1, and deals systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. Section 3 provides a meaningful picture of how these genes operate in infectious disease.