Decellularized Materials Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Decellularized Materials book. This book definitely worth reading, it is an incredibly well-written.
Decellularized Materials by Xiaoming Li,Huiqi Xie Pdf
This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.
Decellularized Extracellular Matrix by Takashi Hoshiba,Tetsuji Yamaoka Pdf
Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.
Cells and Materials for Disease Modeling and Regenerative Medicine by Ander Abarrategi,Senentxu Lanceros-Mendez Pdf
Materials science and engineering are strongly developing tools with increasing impact in the biotechnological and biomedical areas. Interestingly, research in molecular and cellular biology is often at the core of the design and development of materials-based approaches, providing biological rationale. Focused on research relying on biology–materials interaction, IJMS launched a Special Issue named “Cells and Materials for Disease Modeling and Regenerative Medicine”. The aim of the Special Issue was to generate a compilation of in vitro and in vivo strategies based on cell–material interactions. This book compiles the papers published in that Special Issue and includes a selection of six original scientific experimental articles and six comprehensive reviews. We are convinced that this collection of articles shows representative examples of the state of the art in the field, unveiling the relevance of materials research in generating new regenerative medicine and disease modeling approaches.
Decellularized Extracellular Matrix by Tetsuji Yamaoka,Takashi Hoshiba Pdf
The extracellular matrix (ECM) supports cells and regulates various cellular functions in our body. The native ECM promises to provide an excellent scaffold for regenerative medicine. In order to use the ECM as a scaffold in medicine, its cellular fractions need to be removed while retaining its structural and compositional properties. This process is called decellularization, and the resulting product is known as the decellularized extracellular matrix (dECM). This book focuses on the sources of dECM and its preparation, characterization techniques, fabrication, and applications in regenerative medicine and biological studies. Using this book, the reader will gain a good foundation in the field of ECM decellularization complemented with a broad overview of dECM characterization, ranging from structural observation and compositional assessment to immune responses against dECM and applications, ranging from microfabrication and 3D-printing to the application of tissue-derived dECM in vascular grafts and corneal tissue engineering etc. The book closes with a section dedicated to cultured cell dECM, a complementary technique of tissue-derived dECM preparation, for application in tissue engineering and regenerative medicine, addressing its use in stem cell differentiation and how it can help in the study of the tumor microenvironment as well as in clinical trials of peripheral nerve regeneration.
Biomimetic Materials for Tissue Regenerations, 2nd edition by Mariappan Rajan,Stevo J. Najman,Naresh Kumar Rajendran Pdf
In tissue engineering, the ultimate goal is to engineer an entire functioning organ that requires building complex structures of different tissue types. A three-dimensional scaffold seeded with desired cell types. In order to resemble the natural formations of the organs, cells have to be correctly located in relation to one another. It has been shown in cocultures that cells have the capability of spontaneous tissue-like organization when seeded into the scaffold. The ideal scaffolds should have an interconnected porous structure, well-designed pore size and adequate porosity to allow cell attachment, proliferation and differentiation. Moreover, effective bioactive agents and nutrient exchange are crucial during new tissue development. Thus the individual organ cell is a specific mechanism for the construction or regeneration of the cells. Artificial scaffolds have been applied and used as supporting structures for cell cultures as well as for the domination of cell growth in the repair of impaired tissues or organs. During the cell regeneration, the scaffold temporarily helps in cell regeneration and gradually biodegrade either in the course of the healing process or after, and a new tissue with a desired shape and properties is produced. The challenge of tissue engineering is to mimic what happens in nature. Attempts are being made to engineer in vitro practically every tissue and organ in the body. Work is proceeding in creating tissue-engineered liver, nerve, kidney, intestine, pancreas, and even heart muscle and valves. In the area of connective tissues, work has been ongoing worldwide for many years in the engineering of tendon, ligament, bone, and cartilage. Recently, the number of reports was succeeded in skin, bladder, airway, and bone, where tissue-engineered constructs have been used successfully in patients. This Research Topic is the collection of body organ regeneration materials and their cell adhesion and migration for the development and regeneration of tissues. Biomimetic materials promise to advance in current understanding of organ regeneration and repair by providing tools to recapitulate and monitor relevant properties of cellular - microenvironment interactions. Although cell adhesion, migration, and development aspects of tissues have shown success in the clinic, better, more intricate models are needed to understand drivers of tissue repair and regeneration fully. Tissue engineering bears tremendous potential toward gaining a complete understanding of the underlying biological and physical mechanisms advancing the treatment of damaged organs. The following Research Topic “Bio-mimetic materials for tissue regenerations” discusses examples of progress toward this objective. • Bio-mimicking scaffold materials for tissue regeneration • Cell adhesion to scaffold materials • Role of materials for the migration of cells • Mechanisms of cell growth for organ development
The Immune Response to Implanted Materials and Devices by Bruna Corradetti Pdf
This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.
Encyclopedia of Biomedical Engineering by Anonim Pdf
Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field
Decellularized Scaffolds and Organogenesis by Kursad Turksen Pdf
This practical, hands-on volume examines the use of decellularized tissues and organs as biologically-active scaffolds by providing numerous approaches from experts in the field. While knowledge of how to grow and differentiate cells in culture has dramatically improved over time, the book addresses the challenges of how to instruct particular cells of interest to recognize and respond to their environment so as to proliferate, differentiate, and function for restoration of original tissue and organ form and function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Decellularized Scaffolds and Organogenesis: Methods and Protocols share novel approaches and insights that will provide new opportunities for those already in the field or moving to enter the field.
Biomaterials Science by William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski Pdf
The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters
This new important book is a collection of research and review articles from different parts of the world discussing the dynamic and vibrant field of hydrogels. The articles are linking new findings and critically reviewing the fundamental concepts and principles that are making the base for innovation. Each chapter discusses the potential of hydrogels in diverse areas. These areas include tissue engineering, implants, controlled drug release, and oil reserve treatment. The book is offering an up-to-date knowledge of hydrogels to experienced as well as new researchers.
Biomaterials in Tissue Engineering and Regenerative Medicine by Birru Bhaskar,Parcha Sreenivasa Rao,Naresh Kasoju,Vasagiri Nagarjuna,Rama Raju Baadhe Pdf
This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
Bioactive Materials for Disease Diagnosis and Therapy by Dan Shao,Mingqiang Li,Jie Tang,Yuce Li Pdf
With their advantages of controlled delivery and modular flexibility, biomaterials have fundamentally revolutionized disease diagnosis and therapy. Bioactive nanomaterials are not simple miniaturizations of macroscopic materials. They exhibit unique and intrinsic bioactivities as they readily acquire a precise structure upon interaction with the biological environment. Nowadays, bioactive materials offer great potential in eliciting specific responses and regulations of living tissues for diagnostics, therapeutics, and regenerative medicine. We are optimistic that the increasing innovations and advances in bioactive and biomimetic materials with sophisticated bioactivities and controllable responsiveness will make an important contribution to the next generation of biomaterials and biomedical engineering.
Principles of Tissue Engineering by Robert Lanza,Robert Langer,Joseph P. Vacanti Pdf
Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout
Tissue and organ decellularization strategies in regenerative medicine; recent advances, current translational challenges, and future directions by Kamal Hany Hussein,Sotirios Korossis,Laura Iop Pdf