Decellularized Scaffolds And Organogenesis

Author : Kursad Turksen
Publisher : Humana Press
Page : 128 pages
File Size : 55,9 Mb
Release : 2018-07-21
Category : Science
ISBN : 1493976559

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Decellularized Scaffolds and Organogenesis by Kursad Turksen Pdf

This practical, hands-on volume examines the use of decellularized tissues and organs as biologically-active scaffolds by providing numerous approaches from experts in the field. While knowledge of how to grow and differentiate cells in culture has dramatically improved over time, the book addresses the challenges of how to instruct particular cells of interest to recognize and respond to their environment so as to proliferate, differentiate, and function for restoration of original tissue and organ form and function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Decellularized Scaffolds and Organogenesis: Methods and Protocols share novel approaches and insights that will provide new opportunities for those already in the field or moving to enter the field.

Author : Xiaoming Li,Huiqi Xie
Publisher : Springer Nature
Page : 517 pages
File Size : 44,7 Mb
Release : 2021-04-28
Category : Medical
ISBN : 9789813369627

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Decellularized Materials by Xiaoming Li,Huiqi Xie Pdf

This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.

Author : Shuji Miyagawa
Publisher : Unknown
Page : 0 pages
File Size : 46,9 Mb
Release : 2017
Category : Electronic
ISBN : 9535147412

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Xenotransplantation by Shuji Miyagawa Pdf

Author : Melissa Helen Little
Publisher : Academic Press
Page : 614 pages
File Size : 41,7 Mb
Release : 2015-08-06
Category : Medical
ISBN : 9780128004388

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Kidney Development, Disease, Repair and Regeneration by Melissa Helen Little Pdf

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney’s inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Author : Jeffrey M. Gimble,Bruce A. Bunnell
Publisher : Humana Press
Page : 474 pages
File Size : 47,8 Mb
Release : 2011-08-24
Category : Science
ISBN : 1617379611

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Adipose-Derived Stem Cells by Jeffrey M. Gimble,Bruce A. Bunnell Pdf

During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.

Author : Bup Wan Kim
Publisher : Springer
Page : 285 pages
File Size : 51,9 Mb
Release : 2017-09-14
Category : Medical
ISBN : 9789811027239

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Clinical Regenerative Medicine in Urology by Bup Wan Kim Pdf

This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assist in the dissemination of both regenerative medicine principles and a variety of exciting therapeutic options. After an opening section addressing current developments and future perspectives in tissue engineering and regenerative medicine, fundamentals such as cell technologies, biomaterials, bioreactors, bioprinting, and decellularization are covered in detail. The remainder of the book is devoted to the description and evaluation of a range of cell and tissue applications, with individual chapters focusing on the kidney, bladder, urethra, urethral sphincter, and penis and testis.

Author : M. Kusano,S. Shioda
Publisher : Springer Science & Business Media
Page : 164 pages
File Size : 45,9 Mb
Release : 2007-06-04
Category : Medical
ISBN : 9784431382089

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New Frontiers in Regenerative Medicine by M. Kusano,S. Shioda Pdf

Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. In addition to animal experiments, results of research on human tissues and organs are included.

Author : Kamal Hany Hussein,Sotirios Korossis,Laura Iop
Publisher : Frontiers Media SA
Page : 287 pages
File Size : 42,6 Mb
Release : 2023-05-02
Category : Science
ISBN : 9782832521830

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Tissue and organ decellularization strategies in regenerative medicine; recent advances, current translational challenges, and future directions by Kamal Hany Hussein,Sotirios Korossis,Laura Iop Pdf

Author : Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann
Publisher : Springer Science & Business Media
Page : 1049 pages
File Size : 47,6 Mb
Release : 2009-02-11
Category : Medical
ISBN : 9783540777557

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Fundamentals of Tissue Engineering and Regenerative Medicine by Ulrich Meyer,Thomas Meyer,Jörg Handschel,Hans Peter Wiesmann Pdf

"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 762 pages
File Size : 43,5 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527338634

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Tissue Engineering for Artificial Organs, 2 Volume Set by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Author : Abdol-Mohammad Kajbafzadeh
Publisher : Springer Nature
Page : 266 pages
File Size : 48,6 Mb
Release : 2021-09-28
Category : Medical
ISBN : 9783030827359

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Decellularization Methods of Tissue and Whole Organ in Tissue Engineering by Abdol-Mohammad Kajbafzadeh Pdf

This contributed volume is the first of a series that introduces safe, feasible, and practical decellularization and recellularization techniques for tissue and organ reconstruction. We have put special emphasis on the research areas most likely to develop well-engineered scaffolds for tissue and organ engineering, while presenting easily applicable bench-to-bedside approaches highlighting the latest technical innovations in the field. This book includes both a fundamental discussion for a broad understanding of the basis of tissue repair and substitution, as well as chapters written by world renowned specialists from 20 countries providing deeper discussions and analysis of related sub disciplines. Within these pages, the reader will find state-of-the-art protocols and current clinical challenges in cell and tissue biology, including accurate and comprehensive information on extracellular matrices, natural biomaterials, tissue dynamics, morphogenesis, stem cells, cellular fate progressions, cell and tissue properties for in-vitro and in-vivo applications. This comprehensive and carefully organized treatise provides a clear framework for graduate students and postdoctoral researchers new to the field, but also for researchers and practitioners looking to expand their knowledge on tissue and organ reconstruction.

Author : Faheem A. Sheikh
Publisher : Springer Nature
Page : 709 pages
File Size : 43,6 Mb
Release : 2021-10-23
Category : Science
ISBN : 9789811644207

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Engineering Materials for Stem Cell Regeneration by Faheem A. Sheikh Pdf

This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials that can be used for stem cell differentiation. It also elucidates the properties of stem cells, their characteristic features, tissue culture technology, properties of pluripotency, osteogenesis, and biomaterial interaction with de-cellularized organs, cell lineage in vivo and in vitro, gene expression, embryonic development, and cell differentiation. Further, the book reviews the latest applications of bio-instructive scaffold for supporting stem cell differentiation and tissue regeneration. The book also presents stem cell for dental, alveolar bone and cardiac regeneration. Lastly, it introduces engineered stem cells for delivering small molecule therapeutics and their potential biomedical applications.

Author : Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams
Publisher : Academic Press
Page : 1252 pages
File Size : 41,5 Mb
Release : 2017-06-08
Category : Science
ISBN : 9780128018361

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Kidney Transplantation, Bioengineering, and Regeneration by Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams Pdf

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Author : Giuseppe Orlando,Lorenzo Piemonti,Camillo Ricordi,Robert J. Stratta,Rainer W.G. Gruessner
Publisher : Academic Press
Page : 560 pages
File Size : 52,7 Mb
Release : 2019-11-10
Category : Science
ISBN : 9780128148327

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Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas by Giuseppe Orlando,Lorenzo Piemonti,Camillo Ricordi,Robert J. Stratta,Rainer W.G. Gruessner Pdf

Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation, also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine. Provides comprehensive and cutting-edge knowledge of whole pancreas and islet transplantation Addresses imaging, treatment, scaffold technology, the use of stem cells to generate insulin, 3D printing, and more Offers an update on the progress of regenerative medicine research aimed at beta cell replacement for the treatment of diabetes

Author : Daniel Eberli,Sang Jin Lee,Andreas Traweger
Publisher : Springer
Page : 0 pages
File Size : 52,7 Mb
Release : 2021-04-22
Category : Technology & Engineering
ISBN : 3030442101

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Organ Tissue Engineering by Daniel Eberli,Sang Jin Lee,Andreas Traweger Pdf

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.