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Decoding Checkpoint Inhibitor Induced Immune Related Adverse Events Volume Ii Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Decoding Checkpoint Inhibitor Induced Immune Related Adverse Events Volume Ii book. This book definitely worth reading, it is an incredibly well-written.
Author : Deborah L. Burnett,Venessa Tsang,Megan Barnet,Roderick Clifton-Bligh,Katherine Samaras
Publisher : Frontiers Media SA
Page : 121 pages
File Size : 51,5 Mb
Release : 2023-11-14
Category : Medical
ISBN : 9782832538661
Author : Petros Christopoulos,Udo S. Gaipl
Publisher : Frontiers Media SA
Page : 197 pages
File Size : 52,9 Mb
Release : 2024-06-29
Category : Medical
ISBN : 9782832521946
Author : Bo Gao,Da Jing,Xiao Wang,Lei Ma
Publisher : Frontiers Media SA
Page : 259 pages
File Size : 47,5 Mb
Release : 2022-11-09
Category : Science
ISBN : 9782832504710
Author : Yueyong Xiao,Ming Kuang,Nikolai Korpan
Publisher : Frontiers Media SA
Page : 479 pages
File Size : 48,9 Mb
Release : 2024-02-29
Category : Medical
ISBN : 9782832545492
Author : Ralf J. Ludwig ,Frédéric Caux ,Christian David Sadik ,Enno Schmidt,Dedee Murrell,Takashi Hashimoto,Aimee S. Payne
Publisher : Frontiers Media SA
Page : 380 pages
File Size : 53,5 Mb
Release : 2024-06-19
Category : Medical
ISBN : 9782832550595
Pemphigus and pemphigoid diseases are a heterogenous group of autoimmune blistering disorders (AIBD) characterized by tissue-bound and circulating autoantibodies against structural proteins of the desmosome and basement membrane zone of the skin and orifice-close mucosal tissues. While strong evidence has been provided that autoantibodies in AIBD are pathogenic, the exact mechanisms of how blister formation is mediated is very different between pemphigus and pemphigoid disorders and yet incompletely understood. Additionally, target antigens for the major AIBDs have already been identified on the molecular level. In contrast, diagnostic assays are not yet available for all autoantibody specificities and isotypes. Treatment also greatly relies on long-term unspecific immunosuppressants, although rituximab has greatly improved the outcome for patients with moderate and severe pemphigus. There is currently still a need to identify key pathophysiological mediators and pathways for the development of more specific, safer, and more effective treatment options. This Research Topic will honor the work of the late Detlef Zillikens, who has dedicated over 30 years to the field of AIBD and has authored more than 600 articles. We strongly encourage the submission of articles from colleagues and researchers who have collaborated with Prof. Zillikens in the past, however, we will also consider manuscripts from other authors. We would particularly like articles to cite Prof. Zillikens work wherever it is appropriate. We welcome the submission of original research and review articles that cover, but are not limited to, the following sub-topics: • autoantibody specificities • diagnostic assays • in vitro or in vivo studies about the effect of autoantibodies and their modulation • epidemiology and treatment of AIBD Reports of individual cases are discouraged Dr. Enno Schmidt receives grant funding from Euroimmun, Incyte, Dompe, Admirx, Synthon/biondis, Bayer, Pharmix, Alpine Immune, AstraZeneca, Sanofi, ArgenX, UCB, Novartis, Biotest, Fresenius Medical Care, and is consulting for Roche, Imevax, Thermo Fisher, Janssen, Topas, Bristol-Myers Squibb, Almirall, and Chugai. The other Topic Editors declare no potential competing interests in relation to the Research Topic theme.
Author : Raj Nair
Publisher : Springer Nature
Page : 292 pages
File Size : 43,7 Mb
Release : 2022-01-31
Category : Medical
ISBN : 9783030865108
This easy-to-use book equips clinicians and health care professionals with all the information that they will require in order to identify and manage orofacial complications of cancer therapy. Readers will find precise information on the presenting symptoms and signs associated with local or systemic complications associated with individual drugs or modes of therapy in cancer care. Guidance is provided whenever possible on the initial examinations to be performed in each circumstance and the investigations that can deliver a definitive diagnosis. The effective management of cancer complications are explained with the help of up to date clinical practice guidelines for the management of complications secondary to cancer therapy. In addition, an introductory section outlines contemporary principles of cancer management based on precision oral oncology principles. The text is supported by numerous highly informative clinical photographs, tables and a bibliography.
Author : Tamer M. A. Mohamed,Javid Moslehi,Jonathan Satin
Publisher : Frontiers Media SA
Page : 142 pages
File Size : 49,7 Mb
Release : 2022-01-05
Category : Science
ISBN : 9782889719549
Author : Roger Sarrazin,C. Vrousos,François Vincent
Publisher : Unknown
Page : 188 pages
File Size : 50,7 Mb
Release : 1989
Category : Medical
ISBN : UOM:39015014475282
Author : Giampietro Gasparini,Daniel F. Hayes
Publisher : Springer Science & Business Media
Page : 335 pages
File Size : 44,9 Mb
Release : 2008-01-17
Category : Medical
ISBN : 9781592599158
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Author : Wilkes,Margaret Barton-Burke
Publisher : Jones & Bartlett Learning
Page : 1660 pages
File Size : 46,8 Mb
Release : 2016-11-29
Category : Medical
ISBN : 9781284117189
Written especially for nurses caring for patients with cancer, the 2017 Oncology Nursing Drug Handbook uniquely expresses drug therapy in terms of the nursing process: nursing diagnoses, etiologies of toxicities, and key points for nursing assessment, intervention, and evaluation. Updated annually, this essential reference provides valuable information on effective symptom management, patient education, and chemotherapy administration. Completely revised and updated, the 2017 Oncology Nursing Drug Handbook includes separate chapters on molecular and immunologic/biologic targeted therapies. These chapters provide fundamental reviews to assist nurses in understanding the cellular communication pathways disrupted by cancer. It also offers simplified content, attention to understanding the immune checkpoint inhibitors, new information about immunotherapy, new drugs and their indications, and updated indications and side effects for recently FDA approved drugs. New drugs include: alectin
Author : Haidong Dong,Svetomir N. Markovic
Publisher : Springer
Page : 160 pages
File Size : 42,7 Mb
Release : 2018-01-05
Category : Medical
ISBN : 9783319706221
This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.
Author : Ota Fuchs
Publisher : BoD – Books on Demand
Page : 128 pages
File Size : 43,5 Mb
Release : 2021-07-28
Category : Medical
ISBN : 9781839686207
This book deals with the diagnosis and treatment of multiple myeloma. Multiple myeloma is a plasma cell disorder, the prognosis of which has dramatically improved in the last years thanks to new immunomodulatory drugs, proteasome inhibitors, and monoclonal antibodies, in relapsed/refractory disease and a diagnosis. Chapters cover such topics as prognostic and predictive factors in newly diagnosed multiple myeloma, treatment approaches, antibody therapies, and three-dimensional (3D) models mimicking multiple myeloma bone marrow–microenvironment interactions.
Author : Panagiota Economopoulou,Amanda Psyrri,Ranee Mehra
Publisher : Frontiers Media SA
Page : 163 pages
File Size : 47,6 Mb
Release : 2022-01-21
Category : Medical
ISBN : 9782889741328
Author : Andy Hee-Meng Tan,Alice Cheung,Dieter Kabelitz
Publisher : Frontiers Media SA
Page : 120 pages
File Size : 52,9 Mb
Release : 2022-11-11
Category : Medical
ISBN : 9782832505021
Author : Csaba Szabo
Publisher : CRC Press
Page : 354 pages
File Size : 42,7 Mb
Release : 2000-06-22
Category : Medical
ISBN : 9781420038897
Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in mammalian cells, a novel role was proposed for this e
