Diabetes And The Kidney

Author : Christoph Hasslacher,Sonja B¿hm
Publisher : John Wiley & Sons
Page : 146 pages
File Size : 43,5 Mb
Release : 2005-09-01
Category : Medical
ISBN : 9780470021590

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Diabetes and the Kidney by Christoph Hasslacher,Sonja B¿hm Pdf

Diabetes, when untreated, leads to damage to several organs within the body, particularly the kidneys. This damage may also go undetected for several years, until the later stages of kidney failure are reached, with a need for kidney replacement therapy - either dialysis or transplantation. Such progression is not inevitable. With good management, diabetes can be well controlled and kidney function can be maintained; to a certain extent, the damage can even be reversed. Diabetes and the Kidney is written for people with diabetes, their families and carers. It describes the function of the kidneys, the development of nephropathy, the ways to recognize it early and the correct way to manage it. The title emphasizes how people should take responsibility for their own health, with information on diet, giving up smoking and taking exercise. Clearly written description of kidney function, how it goes wrong in diabetic nephropathy and ways to prevent this Guidance on diet, exercise and generally encouraging people to become involved in their own health care Information on treatment of kidney disease and kidney replacement therapy

Author : K.N. Lai,S.C.W. Tang
Publisher : Karger Medical and Scientific Publishers
Page : 288 pages
File Size : 55,7 Mb
Release : 2011-06-08
Category : Medical
ISBN : 9783805597432

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Diabetes and the Kidney by K.N. Lai,S.C.W. Tang Pdf

Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication at hand provides a concise overview of the current state of clinical and basic research in the field. It starts with a summary of the epidemiology and genetics of diabetic nephropathy in different ethnic groups, followed by a review of its clinical manifestation, the link with the metabolic syndrome and obesity, and the pathology of diabetic nephropathy. Building on this basis, the latest findings on pathogenetic, epigenetic and inflammatory mechanisms are presented. The publication also looks at advances in the areas of tubulopathy and the kallikrein-kinin system as well as at the latest animal models and the role of lipoproteins and proteomics. This is followed by a discussion of promising therapeutic approaches such as experimental anti-fibrotic strategies, stem cell therapy and pancreatic transplantation; expert reviews on the emerging entity of new onset diabetes after transplantation and the preventive strategies for diabetic nephropathy conclude the material presented.Written by a panel of leading international experts, this book is highly recommended for nephrologists, diabetologists, internist, transplant physicians, scientists, geneticists, epidemiologists and stem cell biologists working in the field of diabetic nephropathy.

Author : Z.-H. Liui,J.C. He
Publisher : Karger Medical and Scientific Publishers
Page : 277 pages
File Size : 45,7 Mb
Release : 2014-05-16
Category : Medical
ISBN : 9783318026511

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Podocytopathy by Z.-H. Liui,J.C. He Pdf

The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Author : Edgar V. Lerma,Vecihi Batuman
Publisher : Springer Nature
Page : 673 pages
File Size : 43,5 Mb
Release : 2022-01-01
Category : Medical
ISBN : 9783030860202

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Diabetes and Kidney Disease by Edgar V. Lerma,Vecihi Batuman Pdf

This book provides a concise yet comprehensive resource on Diabetic Kidney Disease. Similar to the previous edition, the book reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are also covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease, 2e is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Author : Pedro Cortes
Publisher : Springer Science & Business Media
Page : 564 pages
File Size : 55,6 Mb
Release : 2007-11-06
Category : Medical
ISBN : 9781597451536

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The Diabetic Kidney by Pedro Cortes Pdf

A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Author : C. Sabanayagam,T.Y. Wong
Publisher : Karger Medical and Scientific Publishers
Page : 134 pages
File Size : 47,6 Mb
Release : 2019-06-03
Category : Medical
ISBN : 9783318065077

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Diabetic Retinopathy and Cardiovascular Disease by C. Sabanayagam,T.Y. Wong Pdf

Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the usefulness of DR in CVD risk prediction and cardiovascular safety of anti-VEGF therapy in diabetic patients. There are insights from contemporary diabetic trials that demonstrated the enhanced cardiovascular benefit of novel glucose lowering therapy. It also highlights the potential of novel retinal imaging to predict CVD and its risk factors using the state-of-the art artificial intelligence-based deep learning systems. This book will be an invaluable resource for specialists translating research findings into clinical care, including those in cardiology, endocrinology, ophthalmology, and general practitioners. IT will also be of interest to public health practitioners, researchers, graduate students, and biotech companies interested in developing retinal image-based diagnostic and prognostic tools.

Author : Samy I. McFarlane
Publisher : Bentham Science Publishers
Page : 281 pages
File Size : 48,5 Mb
Release : 2020-03-20
Category : Medical
ISBN : 9789811421990

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Kidney Disease in Diabetes by Samy I. McFarlane Pdf

This reference work provides comprehensive information about diabetic nephropathy. Chapters in the book introduce the reader to the link between diabetes, obesity and chronic kidney disease (CKD) and delve into many topics relevant to treating kidney disease in diabetic patients. These topics include CKD epidemiology, diagnosis, treatment considerations for the elderly patient, post-transplant diabetes, pathophysiology, biomarkers and much more. Special topics such as the incidence of cardiovascular disease in diabetic CKD, nutrition for obese CKD patients and the clinical use of biomarkers for evaluating cases are also included. The broad spectrum coverage of informative topics about diabetic kidney disease make this an essential reference for medical students and clinical residents/healthcare professionals in nephrology, endocrinology, geriatrics, internal medicine and general surgery. Researchers interested in the clinical biochemistry of diabetes and associated disorders will also benefit from the information presented.

Author : A. Treviño-Becerra,K. Iseki
Publisher : Karger Medical and Scientific Publishers
Page : 150 pages
File Size : 52,5 Mb
Release : 2018-01-23
Category : Medical
ISBN : 9783318062519

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Uric Acid in Chronic Kidney Disease by A. Treviño-Becerra,K. Iseki Pdf

Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuricemia is thus expected to be beneficial for both the general population and CKD patients. This book presents new information on uric acid in tubular transport, early recognition of renal lesions, genetic predisposition, preeclampsia, metabolic syndrome, diabetes, high blood pressure in the young, and the relationship with vitamin D. Moreover, the relationship between AKI and uric acid, as well as the rejection of renal transplants due to hyperuricemia, are discussed. This publication will be of interest to both general practitioners and researchers working in the field of CKD. It provides new insights into renal damage caused by hyperuricemia and into prevention and treatment possibilities.

Author : Mark E. Williams
Publisher : Elsevier Health Sciences
Page : 196 pages
File Size : 52,6 Mb
Release : 2011-10-11
Category : Medical
ISBN : 9781455772025

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Diabetic Chronic Kidney Disease, An Issue of Medical Clinics by Mark E. Williams Pdf

This issue of Medical Clinics covers the important advances and current best practices surrounding the management of patients with diabetic chronic kidney disease. Guest edited by Mark Williams of the Joslin Diabetes Clinic, the topics covered will include proteonomics, diabetes and hypertension, obesity, genetic predispositions, pancreas transplantation, fibrotic therapies, and more.

Author : Swayam Prakash Srivastava,Julie Goodwin,Keizo Kanasaki
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 47,6 Mb
Release : 2021-09-10
Category : Science
ISBN : 9782889712830

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Combating Diabetes and Diabetic Kidney Disease by Swayam Prakash Srivastava,Julie Goodwin,Keizo Kanasaki Pdf

Author : Carl Erik Mogensen
Publisher : Springer Science & Business Media
Page : 420 pages
File Size : 55,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475719741

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The Kidney and Hypertension in Diabetes Mellitus by Carl Erik Mogensen Pdf

The first sporadic observations describing renal abnormalities in diabetes were published late in the 19th century, but systematic studies of the kidney in diabetes started only half a century ago after the paper by Cambier in 1934 and the much more famous study by Kimmelstiel and Wilson in 1936. These authors described two distinct features of renal involvement in diabetes: early hyperfiltration and late nephropathy. Diabetic nephropathy is, despite half a century of studies, still a very pertinent problem, renal disease in diabetes now being a very common cause of end-stage renal failure in Europe and North America and probably throughout the world. It is a very important part of the generalized vascular disease found in long-term diabetes as described by Knud Lundbaek in his mono graph Long-term Diabetes in 1953, published by Munks gaard, Copenhagen. Surprisingly, there has not been a comprehensive volume describing all aspects of renal involvement in diabetes, and the time is now ripe for such a volume summarizing the very considerable research activity within this field during the last decade and especially during the last few years. This book attempts to cover practically all aspects of renal involvement in diabetes. It is written by colleagues who are themselves active in the many fields of medical research covered in this volume: epidemiology, physiology and pathophysiology, laboratory methodology, and renal pathology. New studies deal with the dia gnosis and treatment of both incipient and overt nephropathy by metabolie, antihypertensive, and dietary invention.

Author : Takashi Wada,Kengo Furuichi,Naoki Kashihara
Publisher : Springer Nature
Page : 189 pages
File Size : 48,8 Mb
Release : 2020-12-21
Category : Medical
ISBN : 9789811593017

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Diabetic Kidney Disease by Takashi Wada,Kengo Furuichi,Naoki Kashihara Pdf

This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of “classic” diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease.Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments.This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes.

Author : Joris J. Roelofs,Liffert Vogt
Publisher : Springer
Page : 548 pages
File Size : 48,7 Mb
Release : 2018-10-29
Category : Medical
ISBN : 9783319935218

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Diabetic Nephropathy by Joris J. Roelofs,Liffert Vogt Pdf

This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.

Author : George L. Bakris,Allison Hahr,Romesh Khardori,Daisuke Koya,Mark Molitch,Friedrich C. Prischl,Guntram Schernthaner,Bijin Thajudeen
Publisher : Springer
Page : 129 pages
File Size : 51,9 Mb
Release : 2016-07-04
Category : Medical
ISBN : 9783319088730

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Managing Diabetic Nephropathies in Clinical Practice by George L. Bakris,Allison Hahr,Romesh Khardori,Daisuke Koya,Mark Molitch,Friedrich C. Prischl,Guntram Schernthaner,Bijin Thajudeen Pdf

An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes.

Author : Luigi Gnudi,David A. Long
Publisher : Humana
Page : 0 pages
File Size : 43,9 Mb
Release : 2019-11-08
Category : Science
ISBN : 1493998404

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Diabetic Nephropathy by Luigi Gnudi,David A. Long Pdf

This book provides a toolkit of novel research approaches for investigators to study diabetic nephropathy, including critical experimental models from the fly to the fish, cells in culture, and in vivo mammalian approaches. The collection also explores powerful techniques to image the kidney, such as traditional histological techniques as well as electron, confocal, and two-photon microscopy, pathophysiology of the diabetic kidney, and gene editing and regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Diabetic Nephropathy: Methods and Protocols seeks to foster new research directions and inspire ideas to enhance our understanding of diabetic nephropathy and to develop treatments for this condition.