Diagnostic Molecular Pathology In Practice

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Diagnostic Molecular Pathology in Practice

Iris Schrijver

Author : Iris Schrijver
Publisher : Springer Science & Business Media
Page : 329 pages
File Size : 54,9 Mb
Release : 2011-09-09
Category : Medical
ISBN : 9783642196775

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Diagnostic Molecular Pathology in Practice by Iris Schrijver Pdf

This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

Molecular Pathology in Clinical Practice

Debra G.B. Leonard

Author : Debra G.B. Leonard
Publisher : Springer
Page : 1001 pages
File Size : 42,9 Mb
Release : 2016-02-02
Category : Medical
ISBN : 9783319196749

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Molecular Pathology in Clinical Practice by Debra G.B. Leonard Pdf

This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Molecular Pathology in Clinical Practice

Debra G.B. Leonard

Author : Debra G.B. Leonard
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 55,8 Mb
Release : 2007-11-25
Category : Medical
ISBN : 9780387332277

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Molecular Pathology in Clinical Practice by Debra G.B. Leonard Pdf

This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.

Diagnostic Molecular Pathology

William B. Coleman,Gregory J. Tsongalis

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 846 pages
File Size : 40,6 Mb
Release : 2023-10-27
Category : Science
ISBN : 9780128229934

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Diagnostic Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

Molecular Pathology and Diagnostics of Cancer

Domenico Coppola

Author : Domenico Coppola
Publisher : Springer Science & Business Media
Page : 599 pages
File Size : 42,7 Mb
Release : 2013-11-29
Category : Medical
ISBN : 9789400771925

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Molecular Pathology and Diagnostics of Cancer by Domenico Coppola Pdf

Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.

Diagnostic Molecular Pathology

Debra G. B. Leonard

Author : Debra G. B. Leonard
Publisher : Saunders
Page : 236 pages
File Size : 53,8 Mb
Release : 2003
Category : Medical
ISBN : UOM:39015057599691

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Diagnostic Molecular Pathology by Debra G. B. Leonard Pdf

This practical guide provides information essential to understanding the significance of molecular biology and its application to everyday practice. Coverage focuses on the spectrum of currently used molecular tests in the areas of hematopathology, solid tumors, genetics, and identify testing. Examples of both molecular and cytogenetic assays demonstrate how these tests are used in today's pathology labs to detect a wide range of infectious diseases and inherited and metabolic conditions.

Basic Concepts of Molecular Pathology

Philip T. Cagle,Timothy Craig Allen

Author : Philip T. Cagle,Timothy Craig Allen
Publisher : Springer Science & Business Media
Page : 195 pages
File Size : 42,6 Mb
Release : 2009-06-10
Category : Medical
ISBN : 9780387896267

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Basic Concepts of Molecular Pathology by Philip T. Cagle,Timothy Craig Allen Pdf

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Practical Oncologic Molecular Pathology

Yi Ding,Linsheng Zhang

Author : Yi Ding,Linsheng Zhang
Publisher : Springer Nature
Page : 449 pages
File Size : 42,5 Mb
Release : 2021-07-10
Category : Medical
ISBN : 9783030732271

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Practical Oncologic Molecular Pathology by Yi Ding,Linsheng Zhang Pdf

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Cell and Tissue Based Molecular Pathology E-Book

Raymond R. Tubbs,Mark H. Stoler

Author : Raymond R. Tubbs,Mark H. Stoler
Publisher : Elsevier Health Sciences
Page : 452 pages
File Size : 45,9 Mb
Release : 2008-09-22
Category : Medical
ISBN : 9781437719482

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Cell and Tissue Based Molecular Pathology E-Book by Raymond R. Tubbs,Mark H. Stoler Pdf

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook

Martin H. Bluth

Author : Martin H. Bluth
Publisher : Elsevier Health Sciences
Page : 249 pages
File Size : 46,7 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9780323610735

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Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook by Martin H. Bluth Pdf

This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology in Transfusion Medicine; Molecular Diagnosis of Hematopoietic Neoplasms; Molecular Diagnostics in Colorectal Carcinoma; Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix; Molecular Diagnostics in Esophageal and Gastric Neoplasms; Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract; Current Applications of Molecular Genetic Technologies to the Diagnosis and Treatment of Cutaneous Melanocytic Neoplasms; Breast Carcinoma; and Gynecologic Cancers.

Molecular Diagnostics in Cytopathology

Sinchita Roy-Chowdhuri,Paul A. VanderLaan,John M. Stewart,Gilda da Cunha Santos

Author : Sinchita Roy-Chowdhuri,Paul A. VanderLaan,John M. Stewart,Gilda da Cunha Santos
Publisher : Springer
Page : 534 pages
File Size : 44,6 Mb
Release : 2018-11-21
Category : Medical
ISBN : 9783319973975

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Molecular Diagnostics in Cytopathology by Sinchita Roy-Chowdhuri,Paul A. VanderLaan,John M. Stewart,Gilda da Cunha Santos Pdf

Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding. The proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologists and laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Essential components to be presented include: 1) pre-analytic factors that affect sample selection and evaluation; 2) specimen preparation to maximize confidence in results; 3) interpretation of results; 4) potential limitations; and 5) workflow algorithms. In addition, specific disease specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their fields and will include the most up-to-date scientific and clinical information. Molecular Diagnostics in Cytopathology will be of value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents and fellows, Molecular Pathologists, Molecular pathology fellows, Molecular technologists, as well as Translational researchers with an interest in molecular cytopathology.

Microbiology and Molecular Diagnosis in Pathology

Audrey Wanger,Violeta Chavez,Richard Huang,Amer Wahed,Amitava Dasgupta,Jeffrey K. Actor

Author : Audrey Wanger,Violeta Chavez,Richard Huang,Amer Wahed,Amitava Dasgupta,Jeffrey K. Actor
Publisher : Elsevier
Page : 304 pages
File Size : 45,6 Mb
Release : 2017-06-13
Category : Medical
ISBN : 9780128092385

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Microbiology and Molecular Diagnosis in Pathology by Audrey Wanger,Violeta Chavez,Richard Huang,Amer Wahed,Amitava Dasgupta,Jeffrey K. Actor Pdf

Microbiology and Molecular Diagnosis in Pathology: A Comprehensive Review for Board Preparation, Certification and Clinical Practice reviews all aspects of microbiology and molecular diagnostics essential to successfully passing the American Board of Pathology exam. This review book will also serve as a first resource for residents who want to become familiar with the diagnostic aspects of microbiology and molecular methods, as well as a refresher course for practicing pathologists. Opening chapters discuss issues of laboratory management, including quality control, biosafety, regulations, and proper handling and reporting of laboratory specimens. Review chapters give a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites. Following these, coverage focuses on diagnostic tools and specific tests: media for clinical microbiology, specific stains and tests for microbial identifications, susceptibility testing and use of antimicrobial agents, tests for detecting antibodies, antigens, and microbial infections. Two final chapters offer overviews on molecular diagnostics principles and methods as well as the application of molecular diagnostics in clinical practice. Takes a practical and easy-to-read approach to understanding microbiology at an appropriate level for both board preparation as well as a professional refresher course Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner Covers essential concepts in microbiology in such a way that residents, fellows, and clinicians understand the methods and tests without having to become specialists in the field Offers a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites

Principles of Molecular Pathology

Anthony Killeen

Author : Anthony Killeen
Publisher : Springer Science & Business Media
Page : 247 pages
File Size : 45,9 Mb
Release : 2003-11-07
Category : Medical
ISBN : 9781592594313

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Principles of Molecular Pathology by Anthony Killeen Pdf

Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.

Molecular Pathology in Clinical Practice: Infectious Diseases

Debra G.B. Leonard

Author : Debra G.B. Leonard
Publisher : Springer
Page : 0 pages
File Size : 55,7 Mb
Release : 2008-12-12
Category : Medical
ISBN : 0387873678

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Molecular Pathology in Clinical Practice: Infectious Diseases by Debra G.B. Leonard Pdf

Molecular Pathology in Clinical Practice: Infectious Diseases is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular infectious disease testing. The book integrates the latest advancements in the field with the basic principles and practical applications.

Molecular Pathology

William B. Coleman,Gregory J. Tsongalis

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 47,5 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Diagnostic Molecular Pathology In Practice

Diagnostic Molecular Pathology in Practice by Iris Schrijver Pdf

Molecular Pathology in Clinical Practice by Debra G.B. Leonard Pdf

Molecular Pathology in Clinical Practice by Debra G.B. Leonard Pdf

Diagnostic Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Molecular Pathology and Diagnostics of Cancer by Domenico Coppola Pdf

Diagnostic Molecular Pathology by Debra G. B. Leonard Pdf

Basic Concepts of Molecular Pathology by Philip T. Cagle,Timothy Craig Allen Pdf

Practical Oncologic Molecular Pathology by Yi Ding,Linsheng Zhang Pdf

Cell and Tissue Based Molecular Pathology E-Book by Raymond R. Tubbs,Mark H. Stoler Pdf

Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook by Martin H. Bluth Pdf

Molecular Diagnostics in Cytopathology by Sinchita Roy-Chowdhuri,Paul A. VanderLaan,John M. Stewart,Gilda da Cunha Santos Pdf

Microbiology and Molecular Diagnosis in Pathology by Audrey Wanger,Violeta Chavez,Richard Huang,Amer Wahed,Amitava Dasgupta,Jeffrey K. Actor Pdf

Principles of Molecular Pathology by Anthony Killeen Pdf

Molecular Pathology in Clinical Practice: Infectious Diseases by Debra G.B. Leonard Pdf

Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

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