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Author : Renato Cutrera,Francesca Santamaria,Andrew Bush,Nicola Ullmann,Giorgio Piacentini
Publisher : Frontiers Media SA
Page : 103 pages
File Size : 42,8 Mb
Release : 2023-04-12
Category : Medical
ISBN : 9782832520604
Author : Andrew Bush,Giorgio Piacentini,Francesca Santamaria,Nicola Ullmann,Renato Cutrera
Publisher : Unknown
Page : 0 pages
File Size : 42,6 Mb
Release : 2019
Category : Electronic
ISBN : OCLC:1368434590
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Andrew Bush,Giorgio Piacentini,Francesca Santamaria,Nicola Ullmann,Renato Cutrera
Publisher : Frontiers Media SA
Page : 135 pages
File Size : 42,7 Mb
Release : 2019-09-23
Category : Electronic
ISBN : 9782889459865
Globally, severe asthma is defined by the WHO as either (A) untreated severe asthma; (B) difficult-to-treat severe asthma; and (C) treatment-resistant severe asthma. Untreated severe asthma is a political problem: the children do not have access to the basic tools for asthma management, and when this is corrected, asthma outcomes are transformed. The problem in difficult-to-treat severe asthma is not the airway disease, but co-morbidities and behavioral factors. This is the group in which there are most asthma deaths, underscoring that severe asthma cannot be solely defined by levels of prescribed therapy. Treatment-resistant severe asthma is rare and challenging, and the problem is the airway pathology. These children require new and innovative therapies.
Author : Erick Forno,Sejal Saglani
Publisher : Springer Nature
Page : 365 pages
File Size : 40,7 Mb
Release : 2019-11-13
Category : Medical
ISBN : 9783030274313
This book provides readers with a comprehensive review of severe asthma in children and adolescents, covering epidemiology, genetics, risk factors, co-morbidities, clinical presentation, diagnosis and treatment. Written by leaders in the field, chapter discussions draw on the mechanisms driving the disease, genetics, multidisciplinary approaches, immunomodulators, and other important aspects in the management of the disease. Severe Asthma in Children and Adolescents: Mechanisms and Management is designed to be a practical guide, opening with an introduction on the epidemiology of severe childhood asthma, as well as a discussion of special considerations of the disease unique to the preschool-aged patient. The distinctions between the diagnosis and management of asthma in young children of various ages, and specific approaches for the adolescent with severe asthma, including the transition into adult care are then addressed. Finally, the book closes with a discussion on the current state and future avenues for severe asthma research. Severe Asthma in Children and Adolescents is an indispensable reference for the healthcare professional, for basic and translational researchers, as well as for students, residents and fellows.
Author : Kian Fan Chung,Elliot Israel,Peter G. Gibson
Publisher : European Respiratory Society
Page : 360 pages
File Size : 42,8 Mb
Release : 2019-06-01
Category : Medical
ISBN : 9781849841047
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Author : Sandhya Khurana,Fernando Holguin
Publisher : Springer Nature
Page : 334 pages
File Size : 45,7 Mb
Release : 2019-08-29
Category : Medical
ISBN : 9783030208127
This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat’. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art’ reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.
Author : Kai-Håkon Carlsen,Jorrit Gerritsen
Publisher : European Respiratory Society
Page : 246 pages
File Size : 46,8 Mb
Release : 2012-06-01
Category : Medical
ISBN : 9781849840200
Asthma is a disease of many faces and is frequently seen in children. This Monograph covers all aspects of paediatric asthma, across all ages, from birth through to the start of adulthood. It considers diagnostic problems in relation to the many phenotypes of asthma, covers the treatment of both mild-to-moderate and severe asthma, and discusses asthma exacerbations as well as exercise-induced asthma. The issue also provides an update on the pathophysiology of asthma, the role of bacterial and viral infections, and the impact of environmental factors, allergy, genetics and epigenetics. Finally,
Author : World Health Organization
Publisher : World Health Organization
Page : 442 pages
File Size : 41,7 Mb
Release : 2013
Category : Medical
ISBN : 9789241548373
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Author : Stanley J Szefler,Soren Pedersen
Publisher : CRC Press
Page : 744 pages
File Size : 49,9 Mb
Release : 2005-09-26
Category : Medical
ISBN : 9780849352249
This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics will enhance the diagnosis and monitoring of asthma in years to come.
Author : Stanley J. Szefler,Fernando Holguin,Michael E Wechsler
Publisher : Elsevier Health Sciences
Page : 250 pages
File Size : 47,5 Mb
Release : 2017-09-22
Category : Medical
ISBN : 9780323497084
Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. Prepares you to meet your patients’ needs regarding asthma exacerbation prevention and asthma prevention. Consolidates today’s available information and guidance in this timely area into one convenient resource.
Author : Homer A Boushey,Leonardo M Fabbri,Stephen T Holgate
Publisher : CRC Press
Page : 584 pages
File Size : 42,9 Mb
Release : 1999-03-29
Category : Medical
ISBN : 1853175560
This book will redress the balance between knowledge concerning underlying mechanisms and the subsequent consequences of the more severe end of the disease spectrum of asthma.
Author : Liam Heaney,Andrew Menzies
Publisher : JP Medical Ltd
Page : 202 pages
File Size : 42,8 Mb
Release : 2013-03-30
Category : Medical
ISBN : 9789350902998
Most patients with asthma are easily diagnosed and treated with the use of an inhaler or medication. Approximately five per cent of people that suffer from asthma have ‘difficult’ or ‘refractory’ asthma, whereby they experience persistent problems that are not controlled by standard treatment methods. Part of the Clinical Focus Series, this book provides a complete overview of difficult asthma, discussing the clinical assessment and management of this complex condition. Beginning with the epidemiology and characteristics of severe asthma, the book defines current understanding of the immunological mechanisms and disease heterogeneity. It also offers insight into how the condition can affect the physical and psychological aspects of a person’s life. Separate chapters examine novel therapeutic strategies and the economic burden of refractory asthma. Key points Discusses clinical assessment and management of difficult asthma Includes epidemiology, immunology, physical and psychological effects, economic burden and novel therapeutics Internationally renowned author and editor team
Author : K. Fan Chung,E. H. Bel,S. E.. Wenzel,T. Welte
Publisher : Unknown
Page : 308 pages
File Size : 55,6 Mb
Release : 2011
Category : Asthma
ISBN : 1849840091
Author : Theresa Guilbert,Leonard . B Bacharie
Publisher : Elsevier
Page : 128 pages
File Size : 53,6 Mb
Release : 2019-05-03
Category : Electronic
ISBN : 0323677878
This issue of Immunology and Allergy Clinics is devoted to Asthma in Childhood and is Guest Edited by Drs. Leonard Bacharier and Theresa Guilbert. Articles in this outstanding issue include: Inception and Natural History of Pediatric Asthma; Recent Diagnosis Techniques in Pediatric Asthma; Management / co-morbidities for Preschool-aged Children with Asthma; Management/ co-morbidities for School-aged Children with Asthma; Effects of the Environment on Disease Activity; New Advances of Self-Management/Adherence Monitoring and Management in Pediatric Asthma; Severe Asthma in Early Childhood; Inner-city Asthma in Early Childhood; Personalized Medicine and Pediatric Asthma; Prevention in Pediatric Asthma; Asthma in the Schools; and New Directions in Pediatric Asthma.
Author : Graeme P. Currie,John F. W. Baker
Publisher : OUP Oxford
Page : 168 pages
File Size : 52,9 Mb
Release : 2012-08-30
Category : Medical
ISBN : 9780199638918
This 2nd edition provides clinicians with an update on the management of asthma, and includes new sections covering paediatric asthma, new treatment strategies, and updated management guidelines (including new British Thoracic Society [BTS] guidelines).