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Author : Sebastien Dutertre,Maria Vittoria Modica,Mande Holford,Kartik Sunagar
Publisher : Frontiers Media SA
Page : 127 pages
File Size : 52,6 Mb
Release : 2020-05-06
Category : Electronic
ISBN : 9782889637126
Author : Glenn F. King
Publisher : Royal Society of Chemistry
Page : 320 pages
File Size : 53,8 Mb
Release : 2015-01-27
Category : Science
ISBN : 9781782624370
The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Author : P. Gopalakrishnakone,Gerardo A. Corzo,Elia Diego-Garcia,Maria Elena Lima
Publisher : Springer
Page : 0 pages
File Size : 43,7 Mb
Release : 2016-05-10
Category : Medical
ISBN : 9400763883
In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Author : Roseli Pellens,Philippe Grandcolas
Publisher : Springer
Page : 390 pages
File Size : 51,8 Mb
Release : 2016-02-24
Category : Science
ISBN : 9783319224619
This book is about phylogenetic diversity as an approach to reduce biodiversity losses in this period of mass extinction. Chapters in the first section deal with questions such as the way we value phylogenetic diversity among other criteria for biodiversity conservation; the choice of measures; the loss of phylogenetic diversity with extinction; the importance of organisms that are deeply branched in the tree of life, and the role of relict species. The second section is composed by contributions exploring methodological aspects, such as how to deal with abundance, sampling effort, or conflicting trees in analysis of phylogenetic diversity. The last section is devoted to applications, showing how phylogenetic diversity can be integrated in systematic conservation planning, in EDGE and HEDGE evaluations. This wide coverage makes the book a reference for academics, policy makers and stakeholders dealing with biodiversity conservation.
Author : Ronald Jenner,Eivind Undheim
Publisher : Smithsonian Institution
Page : 207 pages
File Size : 53,7 Mb
Release : 2017-10-17
Category : Nature
ISBN : 9781588344540
Venom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.
Author : Francesca Grifo,Joshua Rosenthal
Publisher : Island Press
Page : 0 pages
File Size : 53,9 Mb
Release : 1997-02-01
Category : Health & Fitness
ISBN : 1559635002
The implications of biodiversity loss for the global environment have been widely discussed, but only recently has attention been paid to its direct and serious effects on human health. Biodiversity loss affects the spread of human diseases, causes a loss of medical models, diminishes the supplies of raw materials for drug discovery and biotechnology, and threatens food production and water quality. Biodiversity and Human Health brings together leading thinkers on the global environment and biomedicine to explore the human health consequences of the loss of biological diversity. Based on a two-day conference sponsored by the National Institutes of Health, the National Science Foundation, and the Smithsonian Institution, the book opens a dialogue among experts from the fields of public health, biology, epidemiology, botany, ecology, demography, and pharmacology on this vital but often neglected concern. Contributors discuss the uses and significance of biodiversity to the practice of medicine today, and develop strategies for conservation of these critical resources. Topics examined include: the causes and consequences of biodiversity loss emerging infectious diseases and the loss of biodiversity the significance and use of both prescription and herbal biodiversity-derived remedies indigenous and local peoples and their health care systems sustainable use of biodiversity for medicine an agenda for the future In addition to the editors, contributors include Anthony Artuso, Byron Bailey, Jensa Bell, Bhaswati Bhattacharya, Michael Boyd, Mary S. Campbell, Eric Chivian, Paul Cox, Gordon Cragg, Andrew Dobson, Kate Duffy-Mazan, Robert Engelman, Paul Epstein, Alexandra S. Fairfield, John Grupenhoff, Daniel Janzen, Catherine A. Laughin, Katy Moran, Robert McCaleb, Thomas Mays, David Newman, Charles Peters, Walter Reid, and John Vandermeer. The book provides a common framework for physicians and biomedical researchers who wish to learn more about environmental concerns, and for members of the environmental community who desire a greater understanding of biomedical issues.
Author : David Evans Walter,Heather C. Proctor
Publisher : Springer Science & Business Media
Page : 505 pages
File Size : 41,6 Mb
Release : 2013-10-08
Category : Science
ISBN : 9789400771642
More than 40,000 species of mites have been described, and up to 1 million may exist on earth. These tiny arachnids play many ecological roles including acting as vectors of disease, vital players in soil formation, and important agents of biological control. But despite the grand diversity of mites, even trained biologists are often unaware of their significance. Mites: Ecology, Evolution and Behaviour (2nd edition) aims to fill the gaps in our understanding of these intriguing creatures. It surveys life cycles, feeding behaviour, reproductive biology and host-associations of mites without requiring prior knowledge of their morphology or taxonomy. Topics covered include evolution of mites and other arachnids, mites in soil and water, mites on plants and animals, sperm transfer and reproduction, mites and human disease, and mites as models for ecological and evolutionary theories.
Author : Henning Steinfeld,Pierre Gerber,T. D. Wassenaar,Food and Agriculture Organization of the United Nations,Vincent Castel,Cees de Haan
Publisher : Food & Agriculture Org.
Page : 418 pages
File Size : 41,6 Mb
Release : 2006
Category : Business & Economics
ISBN : 9251055718
"The assessment builds on the work of the Livestock, Environment and Development (LEAD) Initiative"--Pref.
Author : Debmalya Barh,Siomar C. Soares,Sandeep Tiwari,Vasco Ariston De Car Azevedo
Publisher : Academic Press
Page : 476 pages
File Size : 53,8 Mb
Release : 2020-03-06
Category : Science
ISBN : 9780128170779
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics , encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author : Albert O. Bush
Publisher : Cambridge University Press
Page : 580 pages
File Size : 52,9 Mb
Release : 2001-03-22
Category : Medical
ISBN : 0521664470
Explains parasite biology as a branch of ecology - essential reading for zoology and ecology students.
Author : Carmen Viera,Marcelo O. Gonzaga
Publisher : Springer
Page : 448 pages
File Size : 49,7 Mb
Release : 2017-11-02
Category : Science
ISBN : 9783319657172
Within the last few decades, arachnology in the Neotropical region has experienced a great development filling the knowledge gap in one of the most diverse regions of the world. Nevertheless, large geographical areas remain poorly sampled, especially within the Amazon, and new genera and species have been continuously discovered, even in urban areas. In congruence with the recent improvements in research, several aspects of the ecology, behaviour and natural history of spiders, such as interactions with other predators and parasitoids, social interactions, dispersal patterns, habitat requirements, mating behaviors, among others, are being carefully investigated. These recent contributions incorporate substantial information on the preexisting knowledge on these subjects every year. Our main objective with this book is to present a summary on these new researches and on the currently knowledge on the main subjects involved in the general theme, emphasizing the contribution of the rich fauna of the Neotropical region to the research of behaviour and ecology of the spiders.
Author : David Penney
Publisher : Unknown
Page : 322 pages
File Size : 54,6 Mb
Release : 2013
Category : Spiders
ISBN : 9780957453012
The result is a great increase in multi-disciplinary research and novel avenues incorporating spiders as model organisms.
Author : Joris P. G. M. Cromsigt,Sally Archibald,Norman Owen-Smith
Publisher : Cambridge University Press
Page : 453 pages
File Size : 50,6 Mb
Release : 2017-03-02
Category : Business & Economics
ISBN : 9781107031760
This book synthesises key insights from a century of ecological research and monitoring efforts in one of Africa's oldest protected areas.
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Biology,Committee on Research Opportunities in Biology
Publisher : National Academies
Page : 471 pages
File Size : 42,9 Mb
Release : 1989-01-01
Category : Science
ISBN : 9780309039277
Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.
Author : Paul Kingsnorth
Publisher : Graywolf Press
Page : 208 pages
File Size : 42,7 Mb
Release : 2017-08-01
Category : Literary Collections
ISBN : 9781555979720
A provocative and urgent essay collection that asks how we can live with hope in “an age of ecocide” Paul Kingsnorth was once an activist—an ardent environmentalist. He fought against rampant development and the depredations of a corporate world that seemed hell-bent on ignoring a looming climate crisis in its relentless pursuit of profit. But as the environmental movement began to focus on “sustainability” rather than the defense of wild places for their own sake and as global conditions worsened, he grew disenchanted with the movement that he once embraced. He gave up what he saw as the false hope that residents of the First World would ever make the kind of sacrifices that might avert the severe consequences of climate change. Full of grief and fury as well as passionate, lyrical evocations of nature and the wild, Confessions of a Recovering Environmentalist gathers the wave-making essays that have charted the change in Kingsnorth’s thinking. In them he articulates a new vision that he calls “dark ecology,” which stands firmly in opposition to the belief that technology can save us, and he argues for a renewed balance between the human and nonhuman worlds. This iconoclastic, fearless, and ultimately hopeful book, which includes the much-discussed “Uncivilization” manifesto, asks hard questions about how we’ve lived and how we should live.
