Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 42,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Molecular Biology of The Cell
Bruce Alberts
Dna Damage And Repair
Dna Damage And Repair Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Dna Damage And Repair book. This book definitely worth reading, it is an incredibly well-written.
Free-Radical-Induced DNA Damage and Its Repair
Clemens Sonntag
Author : Clemens Sonntag
Publisher : Springer Science & Business Media
Page : 523 pages
File Size : 44,7 Mb
Release : 2006-03-20
Category : Science
ISBN : 9783540305927
Free-Radical-Induced DNA Damage and Its Repair by Clemens Sonntag Pdf
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the cell’s various repair enzymes. Kevin Prise (Cancer Campaign, Gray Laboratory, L- don) was so kind to agree to write this part. However, an adequate description of this strongly expanding area would have exceeded the allocated space by much, and this section had to be omitted. The directors of the Max-Planck-Institut für Strahlenchemie (now MPI für Bioanorganische Chemie), Karl Wieghardt and Wolfgang Lubitz, kindly allowed me to continue to use its facilities after my retirement in 2001. Notably, our - brarian, Mrs. Jutta Theurich, and her right-hand help, Mrs. Rosemarie Schr- er, were most helpful in getting hold of the literature. I thank them very much. Without their constant help, this would have been very difficult indeed.
DNA Damage and Repair
Jac A. Nickoloff,Merl F. Hoekstra
Author : Jac A. Nickoloff,Merl F. Hoekstra
Publisher : Springer Science & Business Media
Page : 1050 pages
File Size : 53,9 Mb
Release : 1998-08-12
Category : Science
ISBN : 9781592594559
DNA Damage and Repair by Jac A. Nickoloff,Merl F. Hoekstra Pdf
Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.
DNA Repair and Mutagenesis
Errol C. Friedberg,Graham C. Walker,Wolfram Siede,Richard D. Wood
Author : Errol C. Friedberg,Graham C. Walker,Wolfram Siede,Richard D. Wood
Publisher : American Society for Microbiology Press
Page : 2587 pages
File Size : 47,7 Mb
Release : 2005-11-22
Category : Science
ISBN : 9781555813192
DNA Repair and Mutagenesis by Errol C. Friedberg,Graham C. Walker,Wolfram Siede,Richard D. Wood Pdf
An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.
DNA Damage and Repair
A. Castellani
Author : A. Castellani
Publisher : Springer Science & Business Media
Page : 377 pages
File Size : 41,9 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781475750164
DNA Damage and Repair by A. Castellani Pdf
The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have their own interna tional meetings and although the meetings often have sessions devoted to DNA repair, they do not bring together a wide diversity of international workers in the field to exchange ideas. The purpose of the Congress was to facilitate such an exchange among scientists representing many fields of endeavor and many countries. The 37 manuscripts in this volume, presented by the invited spea kers during the four and half days of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en dogenous oxidative damages. The Congress and its Proceedings are dedicated to two international leaders in the field of DNA damage and repair, Alexander Hollaender of the United States and Adriano Buzzati Traverso of Italy. Hollaender, who died in December 1986, was one of the first investigators to recognize the damage to DNA was important in cell killing and mutagenesis. His early work indicated that cells could recover from radiation injury.
Technologies for Detection of DNA Damage and Mutations
G.P. Pfeifer
Author : G.P. Pfeifer
Publisher : Springer Science & Business Media
Page : 476 pages
File Size : 46,6 Mb
Release : 1996-07-31
Category : Medical
ISBN : 0306452375
Technologies for Detection of DNA Damage and Mutations by G.P. Pfeifer Pdf
''Useful and timely.'' ---Mutagenesis ''Of considerable value.'' ---Journal of Medical Genetics ''Quite readable....a comprehensive overview....perfectly covers the needs of those researchers who have to decide on the best strategy to identify damage or mutations at the molecular level.'' ---Trends in Cell Biology ''The formats of the presentations are uniform and ample and up-to-date references are provided at the end of each chapter...will be welcomed by postgraduate researchers of all ages and should retain its usefulness for a long time.'' ---Endeavour, 21(4), 1997 This important resource thoroughly reviews a wide range of techniques used in mutagenesis research-ranging from established techniques to recently developed methodologies-based on the polymerase chain reaction. DNA damage analysis, DNA repair assays, and mutation detection are a few of the techniques featured. Chapters present detailed experimental protocols benefiting researchers and students in the fields of toxicology, biotechniques, molecular biology, photobiology, medical genetics, and oncology.
DNA Damage, DNA Repair and Disease Volume 1
R. Stephen Lloyd,Miral Dizdaroglu
Author : R. Stephen Lloyd,Miral Dizdaroglu
Publisher : Royal Society of Chemistry
Page : 429 pages
File Size : 48,9 Mb
Release : 2020-11-19
Category : Science
ISBN : 9781788018890
DNA Damage, DNA Repair and Disease Volume 1 by R. Stephen Lloyd,Miral Dizdaroglu Pdf
The overall aim of this book is to give scientists in academia and industry a comprehensive overview of the field of DNA damage and DNA repair and related human diseases.
DNA
Payam Behzadi
Author : Payam Behzadi
Publisher : BoD – Books on Demand
Page : 235 pages
File Size : 41,5 Mb
Release : 2021-05-19
Category : Medical
ISBN : 9781838810931
DNA by Payam Behzadi Pdf
DNA is the most important biomolecule ever discovered. Indeed, this molecule bears genetic information from one generation to another. In this regard, DNA bases have a key role in transferring genetic information and data safely. However, there are cellular, genetic, and environmental factors that may damage the different parts of DNA molecules. These damages may result in mutations and cell death. As such, several DNA repair mechanisms have evolved. Over three sections, this book examines many of these mechanisms.
DNA Repair Protocols
Lotte Bjergb K
Author : Lotte Bjergb K
Publisher : Humana Press
Page : 652 pages
File Size : 47,7 Mb
Release : 2016-05-01
Category : Medical
ISBN : 1493959549
DNA Repair Protocols by Lotte Bjergb K Pdf
In its 3rd edition, this Methods in Molecular Biology book covers the eukaryotic response to genomic insult including advanced protocols and standard techniques in the field of DNA repair. Offers expert guidance for DNA repair, recombination, and replication."
Advances in DNA Damage and Repair
Miral Dizdaroglu,Ali Esat Karakaya
Author : Miral Dizdaroglu,Ali Esat Karakaya
Publisher : Springer Science & Business Media
Page : 502 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461548652
Advances in DNA Damage and Repair by Miral Dizdaroglu,Ali Esat Karakaya Pdf
In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields.
DNA Damage and Repair
Jac A. Nickoloff,Merl F. Hoekstra
Author : Jac A. Nickoloff,Merl F. Hoekstra
Publisher : Springer Science & Business Media
Page : 417 pages
File Size : 42,7 Mb
Release : 2001-03-13
Category : Science
ISBN : 9781592590957
DNA Damage and Repair by Jac A. Nickoloff,Merl F. Hoekstra Pdf
Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, and explains the important functional relationships among different DNA repair pathways and the relationship between DNA repair pathways, cancer etiology, and cancer therapies.
DNA Repair
Inna Kruman
Author : Inna Kruman
Publisher : BoD – Books on Demand
Page : 652 pages
File Size : 55,7 Mb
Release : 2011-11-07
Category : Medical
ISBN : 9789533076973
DNA Repair by Inna Kruman Pdf
The book consists of 31 chapters, divided into six parts. Each chapter is written by one or several experts in the corresponding area. The scope of the book varies from the DNA damage response and DNA repair mechanisms to evolutionary aspects of DNA repair, providing a snapshot of current understanding of the DNA repair processes. A collection of articles presented by active and laboratory-based investigators provides a clear understanding of the recent advances in the field of DNA repair.
DNA Damage and Repair
Jac A. Nickoloff,Merl F. Hoekstra
Author : Jac A. Nickoloff,Merl F. Hoekstra
Publisher : Springer Science & Business Media
Page : 650 pages
File Size : 46,9 Mb
Release : 1998-01-21
Category : Science
ISBN : UOM:39015040035902
DNA Damage and Repair by Jac A. Nickoloff,Merl F. Hoekstra Pdf
Continuing the tradition of presenting information on DNA damage and repair, this 3rd volume provides the latest reviews by leading researchers. They illuminate key aspects of DNA repair in mammalian systems and its relationship to human disease.
DNA Damage, DNA Repair and Disease
Miral Dizdaroglu,R Stephen Lloyd
Author : Miral Dizdaroglu,R Stephen Lloyd
Publisher : Royal Society of Chemistry
Page : 509 pages
File Size : 50,9 Mb
Release : 2020-11-11
Category : Science
ISBN : 9781839162565
DNA Damage, DNA Repair and Disease by Miral Dizdaroglu,R Stephen Lloyd Pdf
The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.
Mechanisms of DNA Damage and Repair
Michael G. Simic,Lawrence Grossman,Arthur C. Upton,David S. Bergtold
Author : Michael G. Simic,Lawrence Grossman,Arthur C. Upton,David S. Bergtold
Publisher : Springer Science & Business Media
Page : 567 pages
File Size : 55,5 Mb
Release : 2013-11-21
Category : Science
ISBN : 9781461594628
Mechanisms of DNA Damage and Repair by Michael G. Simic,Lawrence Grossman,Arthur C. Upton,David S. Bergtold Pdf
This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.
