Dna Tumour Viruses

Author : Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman
Publisher : Springer Science & Business Media
Page : 440 pages
File Size : 45,6 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781489911001

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DNA Tumor Viruses by Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman Pdf

DNA tumor viruses have long been useful experimental models of carcinogenesis and have elucidated several important mechanisms of cell transformation. Re search in recent years has shown that human tumors have a multifactorial nature and that some DNA tumor viruses may playa key role in their etiology. The aim of this book is to assess our knowledge of DNA tumor viruses by reviewing animal models, mechanisms of transformation, association with human tumors, and possi bilities of prevention and control by vaccination. Animal models of tumor virology have contributed significantly to our under standing of the epidemiology and pathogenesis of virus-induced tumors. Bovine papillomaviruses induce papillomas in the intestine of cattle. The papillomas undergo a transition to carcinomas in cows feeding on bracken fern, which pro duces a toxin with radiomimetic and immunosuppressive functions. This example of cooperation between a virus and chemical carcinogens parallels the cooperative role of human papillomaviruses (HPVs) and herpes simplex virus type 2 (HSV-2) with environmental carcinogens in the pathogenesis of cervical cancer. Likewise, hepatocarcinomas appearing in woodchucks chronically infected by woodchuck hepatitis virus (WIN) provide strong support for the relationship between hepatitis B virus (HBV) infection and human hepatocellular carcinoma. Also, the fact that WIN DNA integrates closely to cellular oncogenes suggests a possible molecular mechanism for the tumorigenesis induced by HBV.

Author : Blossom Damania,James Pipas
Publisher : Springer Science & Business Media
Page : 805 pages
File Size : 42,5 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9780387689456

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DNA Tumor Viruses by Blossom Damania,James Pipas Pdf

This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.

Author : Kevin Gaston
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 48,9 Mb
Release : 2012
Category : Science
ISBN : 1904455999

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Small DNA Tumour Viruses by Kevin Gaston Pdf

Small DNA tumor viruses are a fascinating group of double-stranded DNA viruses, made up of the polyomavirus, the adenovirus, and the papillomavirus families. These viruses continue to provide fundamental insights into mammalian cell transformation, cell cycle control, and tumor formation. The causal link between papillomaviruses and some human cancers is well known, and a role for polyomavirus in human cancer has recently been established. Adenoviruses do not cause cancer in humans, but, as well as providing excellent tools for the study of host cell processes, these viruses have been exploited as delivery vehicles in gene therapy for diseases, such as cystic fibrosis and cancer. A common feature of small DNA tumor viruses is their heavy reliance on the host for survival and replication. Understanding the virus-host relationship is critical to understanding the tumorigenic process and how these viruses subvert the host's immune system. In this timely book, leading scientists from around the world review current hot topics in this area, providing a fascinating overview of the molecular biology of these viruses and their interactions with the host. The topics covered include: HPV infections and the production of HPV virion stocks * viral oncoproteins and their functions * the replication and maintenance of viral genomes * virus-induced alterations in cellular miRNAs * viral deregulation of DNA damage responses * the initiation of viral DNA replication * induction of genomic instability by viral oncoproteins * targeting of PML proteins and PML nuclear bodies by these viruses * adenoviruses and gene therapy. The book will be essential reading for scientists and researchers working on small DNA tumor viruses and their associated diseases. It is also a recommended text for anyone involved with DNA replication, DNA damage responses and genome instability, virus-host interactions, and viral tumorigenesis or antiviral drug development.

Author : Sally Roberts
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 54,9 Mb
Release : 2018-05
Category : Medical
ISBN : 1910190799

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DNA Tumour Viruses by Sally Roberts Pdf

Topics covered range from an overview of the contribution of DNA tumour viruses to the cancer burden worldwide, and the molecular pathogenesis of virus driven cancers to vaccine development.

Author : Leonard J. Rosenthal
Publisher : Karger Medical and Scientific Publishers
Page : 171 pages
File Size : 47,5 Mb
Release : 2001-01-01
Category : Medical
ISBN : 9783805572477

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Mechanisms of DNA Tumor Virus Transformation by Leonard J. Rosenthal Pdf

Approximately 15% of human cancer incidence can be attributed to virus infection, i.e. viruses represent the second most important risk factor (after tobacco consumption) for cancer development in humans. Today, five virus types are known to be involved in causing human cancer: papillomaviruses, retroviruses, herpesviruses, hepadnaviruses, and flaviviruses. This volume provides a comprehensive review of a number of DNA tumor viruses. Leading experts in the field of tumor virology discuss up-to-date information, focusing on the transforming genes of DNA tumor viruses, the mechanisms of transformation and the in vitro methodology used for their identification and characterization. In vitro studies have revealed several common mechanisms of viral transformation. Presented in a clear and concise manner, this book will be of value to students as well as researchers in the fields of general biology, molecular biology, cell biology and microbiology.

Author : James Pipas,Blossom Damania
Publisher : Springer
Page : 826 pages
File Size : 55,6 Mb
Release : 2016-05-01
Category : Medical
ISBN : 1493950592

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DNA Tumor Viruses by James Pipas,Blossom Damania Pdf

This book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. The book represents a comprehensive review of the field of DNA tumor virology.

Author : Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman
Publisher : Springer
Page : 464 pages
File Size : 54,6 Mb
Release : 1995
Category : Medical
ISBN : UOM:39015037299933

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DNA Tumor Viruses by Giuseppe Barbanti-Brodano,Mauro Bendinelli,Herman Friedman Pdf

This single reference on DNA tumor viruses in animal models and humans presents the latest studies on mechanisms of virus transformation, their association with human tumors, and the possibility of prevention and control by vaccination. Chapters provide current information on the epidemiology and pathogenesis of virus-induced tumors and offer insights into future prospects of immunological intervention. Biomedical researchers, clinicians, and virologists will benefit from this key resource.

Author : Samuel Schiminovich
Publisher : Springer Science & Business Media
Page : 265 pages
File Size : 55,7 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468469707

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The Biology of DNA Tumor Viruses by Samuel Schiminovich Pdf

Milestones in Current Research is a series of reprint collections dis tinguished from other such publications by new concepts in preparation, presentation, and intent. The aim of each volume is to gather for a given field the seminal contributions that have defined and shaped the trends within the most active areas of current research. The selections for each volume and the structure of the book have been determined with the help of a novel tech nique of bibliographic analysis and have then been presented to an acknowl edged scientific authority for minor adjustments and the writing of an In troduction. These introductions will lend historic perspective to the material selected for each volume. The bibliographic analysis used tends to select papers central to the areas of current research within, roughly, the last decade and is a systematic procedure for depicting, delineating, and covering all such areas over a wide spectrum of scientific research. It is hoped that with this procedure it will be possible to achieve an objectivity, authority, and thoroughness not reached by others and that the timeliness of the volumes will not be limited to just a few years. Each volume should have the permanent value of a historical statement and yet be suf ficiently interesting to active researchers in the field as well as to students exploring the quiet way in which the relentless drama of research unfolds in the journal literature.

Author : Anonim
Publisher : ScholarlyEditions
Page : 19 pages
File Size : 41,5 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464960253

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DNA Tumor Viruses: Advances in Research and Treatment: 2011 Edition by Anonim Pdf

DNA Tumor Viruses: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about DNA Tumor Viruses in a compact format. The editors have built DNA Tumor Viruses: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about DNA Tumor Viruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of DNA Tumor Viruses: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : Unknown
Page : 1254 pages
File Size : 42,8 Mb
Release : 1984
Category : Oncogenic viruses
ISBN : UOM:39015013229722

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RNA Tumor Viruses: Supplements and appendixes by Anonim Pdf

Author : John Tooze
Publisher : Cold Spring Harbor Laboratory Press
Page : 988 pages
File Size : 50,8 Mb
Release : 1980
Category : Medical
ISBN : UOM:39015000318462

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DNA Tumor Viruses by John Tooze Pdf

Author : Moulay Mustapha Ennaji
Publisher : Academic Press
Page : 459 pages
File Size : 51,8 Mb
Release : 2022-09-14
Category : Science
ISBN : 9780323859134

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Oncogenic Viruses Volume 1 by Moulay Mustapha Ennaji Pdf

Oncogenic Viruses: Fundamentals of Oncoviruses provides an overview of the history of human oncoviruses, how to discover and define an oncovirus, how viruses cause cancer in general, their oncogenic mechanisms and epidemiology, and the cancer biology of oncoviruses. The book is organized into five main parts that include history and discovery of virus-tumor complications, taxonomy and classification of oncoviruses, oncoviruses around the world, including epidemiology statistics and current methods. Finally, the book looks at the molecular epidemiology of DNA and RNA viruses and their role in the pathogenesis of human cancers. Provides an overview of the history, discovery, taxonomy and biology of oncoviruses Offers the fundamentals of viral implications in human tumors Covers the molecular epidemiology and oncologic implications and associations of DNA and RNA oncoviruses

Author : Edouard Kurstak
Publisher : Elsevier
Page : 847 pages
File Size : 52,6 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323142298

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Viruses, Evolution and Cancer Basic Considerations by Edouard Kurstak Pdf

Viruses, Evolution and Cancer: Basic Considerations focuses on comparative biology and evolutionary aspects of DNA and RNA oncogenic viruses. Organized into seven parts, this book begins with a discussion on the host-cell-virus relationships. Some chapters follow that discuss the comparative aspects of DNA and RNA oncogenic viruses. This work also elucidates the effects of oncogenic viruses on cell surface metabolism. Other chapters explore the comparative viral oncology, comparative immunology of oncogenic viruses, and evolution of viruses. This book will be an invaluable material both to those concerned in the scientific and medical problems of cancer and will benefit all who are interested in virology and oncology.

Author : M. A. Epstein,B. G. Achong
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 48,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642672361

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The Epstein-Barr Virus by M. A. Epstein,B. G. Achong Pdf

The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.

Author : Joanna Parish
Publisher : MDPI
Page : 471 pages
File Size : 40,5 Mb
Release : 2018-10-02
Category : Electronic book
ISBN : 9783038421511

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Tumour Viruses by Joanna Parish Pdf

This book is a printed edition of the Special Issue "Tumour Viruses" that was published in Viruses