Drug Delivery Aspects

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Drug Delivery Aspects

Ranjita Shegokar
Drug Delivery Aspects Book PDF

Author : Ranjita Shegokar
Publisher : Academic Press
Page : 268 pages
File Size : 43,6 Mb
Release : 2020-03-27
Category : Business & Economics
ISBN : 9780128218501

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Drug Delivery Aspects by Ranjita Shegokar Pdf

Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses engineering and large-scale manufacturing of nanocarriers Considers preclinical, regulatory and ethical guidelines on nanoparticles Contains in-depth discussions on delivery of biologics, vaccines and sterilisation Industrial view on solid dispersions, milling techniques

Delivery of Drugs

Ranjita Shegokar
Delivery of Drugs Book PDF

Author : Ranjita Shegokar
Publisher : Elsevier
Page : 242 pages
File Size : 44,5 Mb
Release : 2020-02-01
Category : Medical
ISBN : 9780128177778

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Delivery of Drugs by Ranjita Shegokar Pdf

Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems, Volume Two examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects. This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders. This level of discussion makes it a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about the status of drug delivery systems. Delivery of Drugs examines the fabrication, optimization, scale-up, biological aspects, regulatory and clinical success of various micro and nano drug delivery systems. The volume covers site and organ specific targeting approaches, technologies used in preparation of micro - nanoparticles, challenges of complex type of drug delivery forms and role of physical methods in achieving targeted drug effect. Written by a diverse range of international researchers the chapters examine the specific aspects of characterization and manufacturing of drug delivery system for pharmaceutical application and its regulatory aspects. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

Handbook of Non-Invasive Drug Delivery Systems

Vitthal S. Kulkarni
Handbook of Non Invasive Drug Delivery Systems Book PDF

Author : Vitthal S. Kulkarni
Publisher : Elsevier
Page : 328 pages
File Size : 44,5 Mb
Release : 2009-12-31
Category : Medical
ISBN : 0815520263

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Handbook of Non-Invasive Drug Delivery Systems by Vitthal S. Kulkarni Pdf

With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery. The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.

Drug Delivery Trends

Ranjita Shegokar
Drug Delivery Trends Book PDF

Author : Ranjita Shegokar
Publisher : Elsevier
Page : 248 pages
File Size : 48,8 Mb
Release : 2020-03-01
Category : Medical
ISBN : 9780128178713

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Drug Delivery Trends by Ranjita Shegokar Pdf

Drug Delivery Trends examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This volume additionally covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses trends in drug delivery systems and selected dosage forms Illustrates regulatory, preclinical and quality principles Contains in-depth investigation of upcoming types of drug delivery systems

Chemical Aspects of Drug Delivery Systems

D R Karsa,R A Stephenson
Chemical Aspects of Drug Delivery Systems Book PDF

Author : D R Karsa,R A Stephenson
Publisher : Royal Society of Chemistry
Page : 172 pages
File Size : 45,7 Mb
Release : 2007-10-31
Category : Medical
ISBN : 9781847550378

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Chemical Aspects of Drug Delivery Systems by D R Karsa,R A Stephenson Pdf

Despite advances in the development of new drugs, a drug may never reach the target organ, or it may be difficult to achieve the necessary level of drug in the body. Large doses can result in serious side effects and can harm normal, as well as diseased, cells and organs, and for this reason it is vital that controlled release and the targeting of delivery systems must evolve in parallel to drug research. Chemical Aspects of Drug Delivery Systems reflects the modern challenge to devise effective drug delivery and targeting systems, giving particular emphasis to recent innovations in the field. Delivery systems described include carbohydrate derivatives, novel nonionic surfactant vesicles and various polymers, including polyacrylates and aqueous shellac solutions, as well as hydrogels. In addition, many of the key issues, such as the understanding of biosystems and targets and the development of materials to provide the deserved carrier and excipient properties for controlled, targeted drug delivery, are considered in depth. This book will be of equal interest to undergraduate, graduate, researcher and those in the pharmaceutical industries, and it complements two previous RSC Special Publications, Encapsulation and Controlled Release and Excipients and Delivery Systems for Pharmaceutical Formulations.

Nanoparticle Therapeutics

Prashant Kesharwani,Kamalinder K. Singh
Nanoparticle Therapeutics Book PDF

Author : Prashant Kesharwani,Kamalinder K. Singh
Publisher : Academic Press
Page : 674 pages
File Size : 50,5 Mb
Release : 2021-11-06
Category : Technology & Engineering
ISBN : 9780128209189

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Nanoparticle Therapeutics by Prashant Kesharwani,Kamalinder K. Singh Pdf

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

Nanotechnology for Oral Drug Delivery

João Pedro Martins, MSc Biom. Eng.,Hélder A. Santos
Nanotechnology for Oral Drug Delivery Book PDF

Author : João Pedro Martins, MSc Biom. Eng.,Hélder A. Santos
Publisher : Academic Press
Page : 534 pages
File Size : 45,5 Mb
Release : 2020-08-17
Category : Business & Economics
ISBN : 9780128180389

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Nanotechnology for Oral Drug Delivery by João Pedro Martins, MSc Biom. Eng.,Hélder A. Santos Pdf

Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies. Highlights the relevance of oral drug delivery in the clinical setting Covers the most recent advances in the field of nanotechnology for oral drug delivery Provides the scientific community with data that can facilitate and guide their research

Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology

Alexandru Mihai Grumezescu
Nanoscale Fabrication Optimization Scale up and Biological Aspects of Pharmaceutical Nanotechnology Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 696 pages
File Size : 50,9 Mb
Release : 2017-12-11
Category : Science
ISBN : 9780128136300

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Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology by Alexandru Mihai Grumezescu Pdf

Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Design of Controlled Release Drug Delivery Systems

Xiaoling Li
Design of Controlled Release Drug Delivery Systems Book PDF

Author : Xiaoling Li
Publisher : McGraw Hill Professional
Page : 453 pages
File Size : 55,7 Mb
Release : 2005-11-24
Category : Technology & Engineering
ISBN : 9780071588836

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Design of Controlled Release Drug Delivery Systems by Xiaoling Li Pdf

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Drug Delivery Approaches and Nanosystems

Rajesh Kumar Kesharwani,Anil K. Sharma
Drug Delivery Approaches and Nanosystems Book PDF

Author : Rajesh Kumar Kesharwani,Anil K. Sharma
Publisher : Unknown
Page : 0 pages
File Size : 42,9 Mb
Release : 2017-06-16
Category : Drug delivery systems
ISBN : 1771885858

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Drug Delivery Approaches and Nanosystems by Rajesh Kumar Kesharwani,Anil K. Sharma Pdf

V.1. Novel drug carriers -- v.2. Drug targeting aspects of nanotechnology

Nanocarriers for Drug Delivery

Josimar O. Eloy,Juliana Palma Abriata,Juliana Maldonado Marchetti,Juliana Maldonado Marchetti Hernandes
Nanocarriers for Drug Delivery Book PDF

Author : Josimar O. Eloy,Juliana Palma Abriata,Juliana Maldonado Marchetti,Juliana Maldonado Marchetti Hernandes
Publisher : Springer Nature
Page : 347 pages
File Size : 49,6 Mb
Release : 2021
Category : Biomedical materials
ISBN : 9783030633899

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Nanocarriers for Drug Delivery by Josimar O. Eloy,Juliana Palma Abriata,Juliana Maldonado Marchetti,Juliana Maldonado Marchetti Hernandes Pdf

This book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.

Drug Delivery Aspects

Ranjita Shegokar
Drug Delivery Aspects Book PDF

Author : Ranjita Shegokar
Publisher : Elsevier
Page : 266 pages
File Size : 46,8 Mb
Release : 2020-04-13
Category : Business & Economics
ISBN : 9780128212226

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Drug Delivery Aspects by Ranjita Shegokar Pdf

Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses engineering and large-scale manufacturing of nanocarriers Considers preclinical, regulatory and ethical guidelines on nanoparticles Contains in-depth discussions on delivery of biologics, vaccines and sterilisation Industrial view on solid dispersions, milling techniques

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes Book PDF

Author : Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
Publisher : Academic Press
Page : 552 pages
File Size : 45,6 Mb
Release : 2017-05-23
Category : Medical
ISBN : 9780128097182

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Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes by Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer Pdf

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Nano- and Microscale Drug Delivery Systems

Alexandru Mihai Grumezescu
Nano and Microscale Drug Delivery Systems Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 514 pages
File Size : 47,6 Mb
Release : 2017-03-27
Category : Medical
ISBN : 9780323527286

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Nano- and Microscale Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems. Shows how micro- and nanomaterials can be engineered to create more effective drug delivery systems Summarizes current nanotechnology research in the field of drug delivery systems Explores the pros and cons of using particular nanomaterials as therapeutic agents Serves as a valuable reference for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems

Modeling and Control of Drug Delivery Systems

Ahmad Taher Azar
Modeling and Control of Drug Delivery Systems Book PDF

Author : Ahmad Taher Azar
Publisher : Academic Press
Page : 410 pages
File Size : 52,9 Mb
Release : 2021-02-06
Category : Technology & Engineering
ISBN : 9780128211953

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Modeling and Control of Drug Delivery Systems by Ahmad Taher Azar Pdf

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS