Drug Discovery From African Medicinal Plants

Author : Kelly Chibale,Mike Davies-Coleman,Collen Masimirembwa
Publisher : Springer Science & Business Media
Page : 453 pages
File Size : 46,7 Mb
Release : 2012-08-09
Category : Science
ISBN : 9783642281754

Get Book

Drug Discovery in Africa by Kelly Chibale,Mike Davies-Coleman,Collen Masimirembwa Pdf

Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied; from African medicinal plants to marine bioprospecting, pharmacogenetics and the use of nanotechnology. This book brings together for the first time a collection of strategies and techniques that need to be considered when developing drugs in an African setting. It is an unprecedented and truly international effort, highlighting the remarkable effort made so far in the area of drug discovery research by African scientists, and scientists from other parts of the world working on African health problems.

Author : Fidele Ntie-Kang
Publisher : Unknown
Page : 0 pages
File Size : 52,8 Mb
Release : 2021*
Category : Electronic
ISBN : OCLC:1241683743

Get Book

Drug Discovery from African Medicinal Plants by Fidele Ntie-Kang Pdf

African flora, compound libraries, docking, in silico, lead compounds, natural product database, pharmacophore, QSAR, virtual screening.

Author : Victor Kuete
Publisher : Newnes
Page : 916 pages
File Size : 46,9 Mb
Release : 2013-06-19
Category : Science
ISBN : 9780124059368

Get Book

Medicinal Plant Research in Africa by Victor Kuete Pdf

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential The authors are world reknowned African Scientists.

Author : Michael Heinrich,Anna K. Jäger
Publisher : John Wiley & Sons
Page : 462 pages
File Size : 54,9 Mb
Release : 2015-10-12
Category : Medical
ISBN : 9781118930748

Get Book

Ethnopharmacology by Michael Heinrich,Anna K. Jäger Pdf

Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protection, key analytical approaches, the role of ethnopharmacology in primary/secondary education and links to biodiversity and ecological research. Part two looks at ethnopharmacological contributions to modern therapeutics across a range of conditions including CNS disorders, cancer, bone and joint health and parasitic diseases. The final part is devoted to regional perspectives covering all continents, providing a state-of-the –art assessment of the status of ethnopharmacological research globally. A comprehensive, critical synthesis of the latest developments in ethnopharmacology. Includes a section devoted to ethnopharmacological contributions to modern therapeutics across a range of conditions. Contributions are from leading international experts in the field. This timely book will prove invaluable for researchers and students across a range of subjects including ethnopharmacology, ethnobotany, medicinal plant research and natural products research. Ethnopharmacology- A Reader is part of the ULLA Series in Pharmaceutical Sciences www.ullapharmsci.org

Author : Mohamed Neffati,Hanen Najjaa,Ákos Máthé
Publisher : Springer
Page : 411 pages
File Size : 40,9 Mb
Release : 2017-09-07
Category : Technology & Engineering
ISBN : 9789402411201

Get Book

Medicinal and Aromatic Plants of the World - Africa Volume 3 by Mohamed Neffati,Hanen Najjaa,Ákos Máthé Pdf

This volume in the series is devoted to Africa, a continent that possesses a vast treasure of medicinal plants and has produced some exclusive materials for the world market. This volume is expected to strengthen the medicinal plant sector in African countries by making comprehensive information on medicinal and aromatic plants available to policy-makers and entrepreneurs. It can be used to frame effective policies and create an environment conducive to the growth of the plant-based medicine industry, bringing economic benefit to African nations. It will help health organizations to improve the health of their people by using their own resources and a less expensive system of medicine, which is accepted by African society. It could also lead scientific communities to increase R&D activities in the field.

Author : M.M. Iwu,J. Wootton
Publisher : Elsevier
Page : 344 pages
File Size : 55,9 Mb
Release : 2002-03-01
Category : Medical
ISBN : 0080531253

Get Book

Ethnomedicine and Drug Discovery by M.M. Iwu,J. Wootton Pdf

The emergence of new infectious, chronic and drug resistant diseases have prompted scientists to look towards medicinal plants as agents for treatment and prevention. This book provides an interphase between ethnomedical and ethnobotanical approaches to new drug discovery and advances in biotechnology and molecular science that has made it increasingly feasible to transform traditional medicines into modern drugs. These novel approaches also raise new issues and the volume explores economic, ethical and policy considerations of drug development based on indigenous knowledge or traditional medicine. This work also features standardization and development of phytomedicines for major therapeutic indications, including emerging infectious diseases affecting developing and developed countries. The publication provides state-of-the-art information on the most innovative science, the research, the industry, the market, and the future of ethnomedicine and drug discovery.

Author : Victor Kuete
Publisher : Elsevier
Page : 744 pages
File Size : 42,5 Mb
Release : 2014-05-30
Category : Medical
ISBN : 9780128004753

Get Book

Toxicological Survey of African Medicinal Plants by Victor Kuete Pdf

Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems. Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Author : Abayomi Sofowora
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 40,9 Mb
Release : 1982
Category : Medical
ISBN : STANFORD:36105039469932

Get Book

Medicinal Plants and Traditional Medicine in Africa by Abayomi Sofowora Pdf

Author : Victor Kuete
Publisher : Elsevier
Page : 918 pages
File Size : 47,9 Mb
Release : 2013-07-15
Category : Health & Fitness
ISBN : 0323282911

Get Book

Medicinal Plant Research in Africa: Pharmacology and Chemistry by Victor Kuete Pdf

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites.This book explores the essence of natural substances from African medicinal plants and their pharmacological potentialThe authors are world reknowned African Scientists.

Author : Maurice M. Iwu
Publisher : CRC Press
Page : 508 pages
File Size : 49,8 Mb
Release : 2014-02-04
Category : Health & Fitness
ISBN : 9781466571976

Get Book

Handbook of African Medicinal Plants, Second Edition by Maurice M. Iwu Pdf

With over 50,000 distinct species in sub-Saharan Africa alone, the African continent is endowed with an enormous wealth of plant resources. While more than 25 percent of known species have been used for several centuries in traditional African medicine for the prevention and treatment of diseases, Africa remains a minor player in the global natural products market largely due to lack of practical information. This updated and expanded second edition of the Handbook of African Medicinal Plants provides a comprehensive review of more than 2,000 species of plants employed in indigenous African medicine, with full-color photographs and references from over 1,100 publications. The first part of the book contains a catalog of the plants used as ingredients for the preparation of traditional remedies, including their medicinal uses and the parts of the plant used. This is followed by a pharmacognostical profile of 170 of the major herbs, with a brief description of the diagnostic features of the leaves, flowers, and fruits and monographs with botanical names, common names, synonyms, African names, habitat and distribution, ethnomedicinal uses, chemical constituents, and reported pharmacological activity. The second part of the book provides an introduction to African traditional medicine, outlining African cosmology and beliefs as they relate to healing and the use of herbs, health foods, and medicinal plants. This book presents scientific documentation of the correlation between the observed folk use and demonstrable biological activity, as well as the characterized constituents of the plants.

Author : Maurice M. Iwu
Publisher : CRC Press
Page : 458 pages
File Size : 42,9 Mb
Release : 1993-02-18
Category : Science
ISBN : 084934266X

Get Book

Handbook of African Medicinal Plants, Second Edition by Maurice M. Iwu Pdf

Handbook of African Medicinal Plants provides a comprehensive review of over 1,000 species of plants employed in indigenous African medicine. It gives a concise description of the materia medica of an enormous and extensively varied continent, with well over 2,000 distinct tribes and several distinct floras. A detailed pharmacognostical profile of the major herbs is presented, including the common name, synonyms, African names, habitat and distribution, medicinal uses, chemical constituents, and published pharmacologic activity. This extensive catalog of plants is presented both in alphabetic order and according to family. References are cited from over 600 publications, and photographs and sketches illustrate many of the plants. The book also provides an introduction to African cosmology and beliefs as they relate to healing and the use of herbs. Handbook of African Medicinal Plants is an invaluable, practical desk reference that should be on the bookshelf of every pharmacognosist, ethnobiologist, botanist, ecologist, phytochemist, pharmacologist, and scientist interested in tropical plant utilization as a tool for the conservation of biodiversity and as a source of new drug leads.

Author : Abayomi Sofowora
Publisher : Unknown
Page : 234 pages
File Size : 47,7 Mb
Release : 1979
Category : Botany, Medical
ISBN : STANFORD:36105038892944

Get Book

African Medicinal Plants by Abayomi Sofowora Pdf

Author : J. O. Kokwaro
Publisher : University of Nairobi Press
Page : 22 pages
File Size : 41,6 Mb
Release : 2009
Category : Health & Fitness
ISBN : 9789966846846

Get Book

Medicinal Plants of East Africa by J. O. Kokwaro Pdf

Medicinal Plants of East Africa is a revised edition of the book first published in 1976 on herbal remedies and he traditional medical practice of East Africa. The book covers the rich diversity of plants found in Kenya, Tanzania and Uganda, from sea to alpine plants. East Africa also has a rich ethnic diversity and a large number of herbalists whose traditional knowledge and practices are also covered in the book. Over 1500 species are described and for the first time over 200 of these herbs have been illustrated. Also included are maps detailing where the herbs were collected and an ethnographic map detailing the tribes of each herbalist whose knowledge is contained in the book. John Kokwaro is an Eminent Professor of Botany and a research specialist on herbal remedies at the University of Nairobi.

Author : Shagufta Perveen,Areej Al-Taweel
Publisher : BoD – Books on Demand
Page : 322 pages
File Size : 49,6 Mb
Release : 2019-06-19
Category : Medical
ISBN : 9781838806101

Get Book

Pharmacognosy by Shagufta Perveen,Areej Al-Taweel Pdf

Pharmacognosy is a term derived from the Greek words for drug (pharmakon) and knowledge (gnosis). It is a field of study within Chemistry focused on natural products isolated from different sources and their biological activities. Research on natural products began more than a hundred years ago and has continued up to now with a plethora of research groups discovering new ideas and novel active constituents. This book compiles the latest research in the field and will be of interest to scientists, researchers, and students.

Author : Chukwuebuka Egbuna,Muhammad Akram,Jonathan Chinenye Ifemeje
Publisher : John Wiley & Sons
Page : 628 pages
File Size : 46,8 Mb
Release : 2021-11-09
Category : Science
ISBN : 9781119616603

Get Book

Neglected Tropical Diseases and Phytochemicals in Drug Discovery by Chukwuebuka Egbuna,Muhammad Akram,Jonathan Chinenye Ifemeje Pdf

NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.